CHEMBL240584


SMILES COc1ccccc1N1CCN(CCCCCNC(=O)c2cccc(C#Cc3ccccc3)c2)CC1
InChIKey UBFCDXVLKFOOGL-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 9
Molecular weight (Da) 481.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Pig Dopamine A pKi 6.23 6.23 6.23 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.46 7.46 7.46 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.43 7.43 7.43 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.51 7.54 7.57 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database