CHEMBL240657


SMILES O=C1NCN(c2ccccc2)C12CCN(C(c1ccccc1)c1ccccc1)CC2
InChIKey MLVHNSLPGKIYBU-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 397.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 7.64 7.64 7.64 ChEMBL
δ OPRD Human Opioid A pKi 4.42 4.42 4.42 ChEMBL
κ OPRK Human Opioid A pKi 6.86 6.86 6.86 ChEMBL
μ OPRM Human Opioid A pKi 6.31 6.31 6.31 ChEMBL
NOP OPRX Human Opioid A pKi 7.64 7.64 7.64 PDSP Ki database
μ OPRM Human Opioid A pKi 6.31 6.31 6.31 PDSP Ki database
δ OPRD Human Opioid A pKi 5.0 5.0 5.0 PDSP Ki database
κ OPRK Human Opioid A pKi 6.86 6.86 6.86 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database