CHEMBL222371


SMILES CC(Oc1ccccc1-c1cccc(N)c1)C1=NCCN1
InChIKey YVSAGYHRJDVYHG-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 4
Molecular weight (Da) 281.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Human Adrenoceptors A pKi 6.32 6.32 6.32 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 6.51 6.51 6.51 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 7.43 7.43 7.43 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2C ADA2C Human Adrenoceptors A pEC50 6.3 6.3 6.3 ChEMBL
α2A ADA2A Human Adrenoceptors A pEC50 6.59 6.59 6.59 ChEMBL