CHEMBL241436


SMILES O=C(NCCCCN1CCN(c2cccc(Cl)c2Cl)CC1)c1cccc(C#Cc2ccccc2)c1
InChIKey RFRIYEZLKPZDGU-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 505.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Pig Dopamine A pKi 5.75 5.75 5.75 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.72 6.72 6.72 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.12 8.12 8.12 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.62 6.65 6.68 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database