CHEMBL2437063


SMILES CN1CC[C@]23c4c5ccc(O)c4O[C@H]2[C@H](NC(=O)/C=C/c2ccccc2)C=C[C@H]3[C@H]1C5
InChIKey HBGUKHSNIWDVFP-XUZRCCIISA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 3
Molecular weight (Da) 414.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Mouse Opioid A pKi 8.54 8.54 8.54 ChEMBL
μ OPRM Mouse Opioid A pKi 10.0 10.0 10.0 ChEMBL
δ OPRD Mouse Opioid A pKi 7.99 7.99 7.99 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Mouse Opioid A pEC50 7.44 7.44 7.44 ChEMBL
μ OPRM Mouse Opioid A pEC50 8.86 8.86 8.86 ChEMBL
δ OPRD Mouse Opioid A pEC50 8.04 8.04 8.04 ChEMBL