CHEMBL228795


SMILES OC1(c2ccccc2)CCN(C(c2ccccc2)c2ccc(C(F)(F)F)cc2)CC1
InChIKey GTMJMDBNWVOYOR-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 411.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 6.65 6.65 6.65 ChEMBL
δ OPRD Human Opioid A pKi 5.0 5.0 5.0 ChEMBL
κ OPRK Human Opioid A pKi 5.37 5.37 5.37 ChEMBL
μ OPRM Human Opioid A pKi 5.92 5.92 5.92 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database