CHEMBL2443005


SMILES COc1ccccc1N1CCN(Cc2cn(-c3ccc(OCCCF)cc3)nn2)CC1
InChIKey XUOARYPFOGJNNV-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 0
Rotatable bonds 9
Molecular weight (Da) 425.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
β1 ADRB1 Pig Adrenoceptors A pKi 6.89 6.89 6.89 ChEMBL
D1 DRD1 Pig Dopamine A pKi 4.42 4.42 4.42 ChEMBL
D4 DRD4 Human Dopamine A pKi 8.29 8.29 8.29 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.55 5.55 5.55 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.28 6.38 6.47 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database