CHEMBL231184


SMILES Cc1ccc(-n2c(C)ccc2-c2cc(Cl)ccc2OCc2ccc(F)cc2)cc1C(=O)O
InChIKey YNGYDYOYWOAUDY-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 449.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP1 PE2R1 Human Prostanoid A pKi 9.0 9.0 9.0 ChEMBL
EP3 PE2R3 Human Prostanoid A pKi 6.3 6.3 6.3 ChEMBL
EP4 PE2R4 Human Prostanoid A pKi 5.1 5.15 5.2 ChEMBL
TP TA2R Human Prostanoid A pKi 7.8 7.8 7.8 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP1 PE2R1 Human Prostanoid A pIC50 8.3 8.3 8.3 ChEMBL
EP4 PE2R4 Human Prostanoid A pIC50 4.8 4.8 4.8 ChEMBL
TP TA2R Human Prostanoid A pIC50 7.4 7.4 7.4 ChEMBL