Chembl247664

Chemical Properties

SMILES COc1cc2c(cc1OC)CN(Cc1ccc(OC)c3oc(C(=O)NCC(C)(C)N)cc13)CC2
Hydrogen bond acceptors 7
Hydrogen bond donors 2
Rotatable bonds 8
Molecular weight 467.2

Drug Properties

Type Small molecule
Endogenous No
Approved No
InChIKey JYEPTVGXWUQMKF-UHFFFAOYSA-N

Database Connections

External Links


Bioactivity

Receptor Experimental Data Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Human Adrenoceptors A pKi 5.81 5.81 5.81 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 8.38 8.38 8.38 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 6.85 6.85 6.85 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 5.85 5.85 5.85 PDSP KiDatabase
α2B ADA2B Human Adrenoceptors A pKi 4.81 4.81 4.81 PDSP KiDatabase
α2C ADA2C Human Adrenoceptors A pKi 7.38 7.38 7.38 PDSP KiDatabase