CHEMBL232477


SMILES CNCc1ccccc1C1(O)CCN(C(c2ccccc2Cl)c2ccccc2Cl)CC1
InChIKey CIUZZWVDZRCBDX-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 6
Molecular weight (Da) 454.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 9.15 9.15 9.15 ChEMBL
δ OPRD Human Opioid A pKi 5.42 5.42 5.42 ChEMBL
κ OPRK Human Opioid A pKi 6.59 6.59 6.59 ChEMBL
μ OPRM Human Opioid A pKi 6.78 6.78 6.78 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database