CHEMBL250699


SMILES COc1cc(NC(=O)c2ccc(-c3ccc(Cl)cc3)o2)cc(OC)c1
InChIKey VHKBTPQDHDSBSP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 357.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Human Dopamine A pIC50 5.16 5.16 5.16 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pIC50 5.0 5.0 5.0 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pIC50 5.52 5.52 5.52 ChEMBL
A3 AA3R Human Adenosine A pIC50 4.92 4.92 4.92 ChEMBL
A2A AA2AR Human Adenosine A pIC50 5.0 5.0 5.0 ChEMBL
μ OPRM Human Opioid A pIC50 5.0 5.0 5.0 ChEMBL
CB1 CNR1 Human Cannabinoid A pIC50 5.0 5.0 5.0 ChEMBL