Chembl254754


SMILES COc1cc(CC(=O)N(C)[C@H](CN2CC[C@H](O)C2)c2ccccc2)c(S(=O)(=O)N2CCN(C)CC2)cc1OC
InChIKey HYJLRKAZCMRYMO-BJKOFHAPSA-N

Chemical properties

Hydrogen bond acceptors 8
Hydrogen bond donors 1
Rotatable bonds 10
Molecular weight (Da) 560.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections


Bioactivity

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 8.36 8.36 8.36 ChEMBL
κ OPRK Human Opioid A pKi 8.42 8.42 8.42 ChEMBL
κ OPRK Human Opioid A pEC50 9.15 9.15 9.15 ChEMBL
μ OPRM Human Opioid A pKi 7.57 7.57 7.57 ChEMBL