MTEB


SMILES N#Cc1cccc(c1)C#Cc1csc(n1)C
InChIKey GRUPMMBRLDBTDD-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 0
Molecular weight (Da) 224.0

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu5 GRM5 Rat Metabotropic glutamate C pKi 9.6 9.6 9.6 ChEMBL
mGlu5 GRM5 Human Metabotropic glutamate C pKi 9.43 9.43 9.43 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu5 GRM5 Human Metabotropic glutamate C pIC50 8.7 8.7 8.7 Guide to Pharmacology
mGlu5 GRM5 Human Metabotropic glutamate C pIC50 9.03 9.03 9.03 ChEMBL