CHEMBL252956


SMILES O=C1CCCc2nc(C#Cc3ccccc3)ccc21
InChIKey XOUDFZJCSDKXLG-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 0
Molecular weight (Da) 247.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu5 GRM5 Rat Metabotropic glutamate C pKi 6.1 6.1 6.1 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu5 GRM5 Rat Metabotropic glutamate C pEC50 7.47 7.47 7.47 ChEMBL
mGlu5 GRM5 Human Metabotropic glutamate C pEC50 6.76 7.44 7.85 ChEMBL