neurokinin A


SMILES None
InChIKey HEAUFJZALFKPBA-JPQUDPSNSA-N
Sequence HKTDSFVGLM

Chemical properties

Hydrogen bond acceptors None
Hydrogen bond donors None
Rotatable bonds None
Molecular weight (Da)

Drug properties

Molecular type Peptide
Physiological/Surrogate Endogenous
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NK1 NK1R Human Tachykinin A pKi 6.2 7.75 9.3 Guide to Pharmacology
NK3 NK3R Human Tachykinin A pKi 5.5 5.9 6.3 Guide to Pharmacology
NK3 NK3R Mouse Tachykinin A pKi 6.1 6.1 6.1 Guide to Pharmacology
NK2 NK2R Human Tachykinin A pKd 9.3 9.3 9.3 Guide to Pharmacology
NK2 NK2R Human Tachykinin A pKi 8.0 8.55 9.1 Guide to Pharmacology
NK2 NK2R Human Tachykinin A pKi 8.92 9.04 9.15 ChEMBL
NK1 NK1R Human Tachykinin A pKi 6.2 6.2 6.2 ChEMBL
NK2 NK2R Guinea pig Tachykinin A pKi 5.43 5.43 5.43 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NK3 NK3R Human Tachykinin A pEC50 7.4 7.4 7.4 Guide to Pharmacology
NK2 NK2R Guinea pig Tachykinin A pEC50 8.89 8.89 8.89 Guide to Pharmacology
NK3 NK3R Rat Tachykinin A pEC50 6.25 6.25 6.25 ChEMBL
NK2 NK2R Rat Tachykinin A pEC50 7.19 8.41 9.26 ChEMBL
NK2 NK2R Human Tachykinin A pIC50 8.11 8.44 8.77 ChEMBL
NK3 NK3R Human Tachykinin A pEC50 7.28 7.28 7.28 ChEMBL
NK3 NK3R Human Tachykinin A pIC50 7.35 7.35 7.35 ChEMBL
NK2 NK2R Golden hamster Tachykinin A pIC50 9.0 9.0 9.0 ChEMBL
NK1 NK1R Guinea pig Tachykinin A pIC50 8.46 8.46 8.46 ChEMBL
NK1 NK1R Guinea pig Tachykinin A pEC50 7.86 7.86 7.86 ChEMBL
NK1 NK1R Rat Tachykinin A pIC50 7.5 7.5 7.51 ChEMBL