neurokinin B


SMILES None
InChIKey NHXYSAFTNPANFK-HDMCBQFHSA-N
Sequence DMHDFFVGLM

Chemical properties

Hydrogen bond acceptors None
Hydrogen bond donors None
Rotatable bonds None
Molecular weight (Da)

Drug properties

Molecular type Peptide
Physiological/Surrogate Endogenous
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NK1 NK1R Human Tachykinin A pKi 6.1 6.25 6.4 Guide to Pharmacology
NK2 NK2R Human Tachykinin A pKi 5.0 6.35 7.7 Guide to Pharmacology
NK3 NK3R Human Tachykinin A pKi 7.7 8.45 9.2 Guide to Pharmacology
NK3 NK3R Mouse Tachykinin A pKi 8.6 8.65 8.7 Guide to Pharmacology
NK3 NK3R Human Tachykinin A pKi 9.1 9.1 9.1 ChEMBL
NK2 NK2R Human Tachykinin A pKi 7.38 7.59 7.8 ChEMBL
NK1 NK1R Human Tachykinin A pKi 6.3 6.3 6.3 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NK3 NK3R Human Tachykinin A pEC50 8.4 8.4 8.4 Guide to Pharmacology
NK3 NK3R Guinea pig Tachykinin A pIC50 8.0 8.35 8.7 ChEMBL
NK2 NK2R Golden hamster Tachykinin A pIC50 7.75 8.09 8.44 ChEMBL
NK1 NK1R Guinea pig Tachykinin A pEC50 7.17 7.17 7.17 ChEMBL
NK1 NK1R Guinea pig Tachykinin A pIC50 7.89 7.89 7.89 ChEMBL
NK3 NK3R Human Tachykinin A pIC50 7.12 7.93 8.52 ChEMBL
NK3 NK3R Human Tachykinin A pEC50 8.22 8.22 8.22 ChEMBL
NK2 NK2R Human Tachykinin A pIC50 6.99 6.99 6.99 ChEMBL
NK1 NK1R Human Tachykinin A pIC50 7.01 7.01 7.01 ChEMBL
NK2 NK2R Rat Tachykinin A pEC50 7.57 7.57 7.57 ChEMBL
NK3 NK3R Rat Tachykinin A pEC50 8.2 8.2 8.2 ChEMBL
NK1 NK1R Rat Tachykinin A pIC50 6.06 6.61 7.16 ChEMBL