CHEMBL259476


SMILES Cc1c(C(=O)NN2CCCCC2)nn(-c2ccc(Cl)cc2Cl)c1-n1c(C)ccc1C
InChIKey PLPHADTYPPFRRC-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 445.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CB2 CNR2 Human Cannabinoid A pKi 6.01 6.01 6.01 ChEMBL
CB1 CNR1 Human Cannabinoid A pKi 7.42 7.42 7.42 ChEMBL
CB1 CNR1 Human Cannabinoid A pKi 7.42 7.42 7.42 PDSP Ki database
CB2 CNR2 Human Cannabinoid A pKi 6.01 6.01 6.01 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CB2 CNR2 Human Cannabinoid A pIC50 5.91 5.91 5.91 ChEMBL
CB1 CNR1 Human Cannabinoid A pIC50 7.17 7.17 7.17 ChEMBL