CHEMBL112831


SMILES COc1cc(N)c(Cl)cc1C(=O)N[C@H]1CCCN(Cc2ccccc2)C1
InChIKey NKNTXYMZEFEUNK-HNNXBMFYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 5
Molecular weight (Da) 373.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Bovine Dopamine A pKi 4.77 4.83 4.89 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.28 6.49 6.7 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.06 5.3 5.54 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.1 5.56 5.96 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database