Chembl26181


SMILES CCCN(CCC)[C@@H]1Cc2cccc3nc(O)n(c23)C1
InChIKey UCZYAFAFGFTZEW-CYBMUJFWSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 273.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Bioactivity

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Rat Dopamine A pKi 7.17 7.72 8.27 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.04 7.42 7.61 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.57 7.57 7.57 ChEMBL
D3 DRD3 Human Dopamine A pEC50 7.66 7.66 7.66 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.94 8.36 8.77 ChEMBL
D2 DRD2 Human Dopamine A pEC50 8.6 8.6 8.6 ChEMBL