AZ8838
SMILES | CCCc1cc(F)ccc1[C@@H](c1ncc[nH]1)O |
InChIKey | IDFPQEHZYBXIFO-LBPRGKRZSA-N |
Chemical properties
Hydrogen bond acceptors | 2 |
Hydrogen bond donors | 2 |
Rotatable bonds | 4 |
Molecular weight (Da) | 234.1 |
Drug properties
Molecular type | Small molecule |
Endogenous/Surrogate | Surrogate |
Approved drug | No |
Database connections
Structure pdb | 5NDD |
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
PAR2 | PAR2 | Human | Proteinase-activated | A | pKd | 6.46 | 6.46 | 6.46 | Guide to Pharmacology |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
PAR2 | PAR2 | Human | Proteinase-activated | A | pIC50 | 5.73 | 5.73 | 5.73 | Guide to Pharmacology |
PAR2 | PAR2 | Human | Proteinase-activated | A | pIC50 | 5.38 | 5.38 | 5.38 | ChEMBL |