Chembl114379

Chemical Properties

SMILES Oc1nc2ccccc2n1C1CCN(Cc2cc3c(cc2Cl)OCO3)CC1
Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight 385.1

Drug Properties

Type Small molecule
Endogenous No
Approved No
InChIKey QETCNYZNLBVXLI-UHFFFAOYSA-N

Database Connections

External Links


Bioactivity

Receptor Experimental Data Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pIC50 7.42 7.42 7.42 ChEMBL
M5 ACM5 Human Acetylcholine (muscarinic) A pIC50 5.72 5.72 5.72 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pIC50 6.12 6.12 6.12 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pIC50 6.29 6.29 6.29 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pIC50 6.2 6.2 6.2 ChEMBL
D3 DRD3 Human Dopamine A pIC50 5.72 5.72 5.72 ChEMBL
δ OPRD Human Opioid A pIC50 7.43 7.43 7.43 ChEMBL
κ OPRK Human Opioid A pIC50 8.77 8.77 8.77 ChEMBL
μ OPRM Human Opioid A pIC50 8.92 8.92 8.92 ChEMBL