CHEMBL269612


SMILES COc1ccc2c(c1)CCC=C2CCCN1CCN(c2ccccc2OC)CC1
InChIKey QSSXSMKCIZLOKB-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight (Da) 392.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Rat Dopamine A pKi 7.65 7.65 7.65 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 8.75 8.75 8.75 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Rat Dopamine A pIC50 7.04 7.04 7.04 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pIC50 8.7 8.7 8.7 ChEMBL