CHEMBL2392176


SMILES COc1ccccc1C(=O)Nc1cc(Br)cc2c(=O)cc(C(=O)O)oc12
InChIKey NFUILGBRJQDWLM-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 4
Molecular weight (Da) 417.0

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
GPR35 GPR35 Human A orphans A pKi 6.48 6.48 6.48 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
GPR35 GPR35 Mouse A orphans A pEC50 5.3 5.3 5.3 ChEMBL
GPR35 Q33BM1 Rat A orphans A pEC50 5.96 5.96 5.96 ChEMBL
GPR35 GPR35 Human A orphans A pEC50 5.78 5.78 5.78 ChEMBL