CHEMBL2392177


SMILES COc1ccc(C(=O)Nc2cc(Br)cc3c(=O)cc(C(=O)O)oc23)cc1OC
InChIKey YXPZMXSVNGLVQP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 5
Molecular weight (Da) 447.0

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
GPR35 GPR35 Human A orphans A pKi 6.64 6.64 6.64 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
GPR35 GPR35 Mouse A orphans A pEC50 5.19 5.19 5.19 ChEMBL
GPR35 Q33BM1 Rat A orphans A pEC50 5.89 5.89 5.89 ChEMBL
GPR35 GPR35 Human A orphans A pEC50 6.2 6.31 6.37 ChEMBL