CHEMBL273671


SMILES CCCn1c(=O)c2nc(-c3ccc(Cl)cc3N)[nH]c2n(CCC)c1=O
InChIKey SENJBFBVCXOUFE-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 5
Molecular weight (Da) 361.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
A2A AA2AR Guinea pig Adenosine A pKi 6.0 6.0 6.0 ChEMBL
A1 AA1R Bovine Adenosine A pKi 10.66 10.66 10.66 ChEMBL
A1 AA1R Rat Adenosine A pKi 8.32 8.53 8.6 ChEMBL
A1 AA1R Rat Adenosine A pKi 8.17 8.17 8.17 PDSP Ki database
A1 AA1R Bovine Adenosine A pKi 9.52 9.52 9.52 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
A1 AA1R Bovine Adenosine A pIC50 10.3 10.3 10.3 ChEMBL