CHEMBL271782


SMILES Cc1c(C(=O)NC2CCCCC2)nn(-c2c(Cl)cc(Cl)cc2Cl)c1-n1c(C)ccc1C
InChIKey LYXKAOOQSNYNDL-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 478.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CB2 CNR2 Human Cannabinoid A pKi 6.41 6.41 6.41 ChEMBL
CB1 CNR1 Human Cannabinoid A pKi 7.55 7.55 7.55 ChEMBL
CB1 CNR1 Human Cannabinoid A pKi 7.55 7.55 7.55 PDSP Ki database
CB2 CNR2 Human Cannabinoid A pKi 6.41 6.41 6.41 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CB2 CNR2 Human Cannabinoid A pIC50 6.3 6.3 6.3 ChEMBL
CB1 CNR1 Human Cannabinoid A pIC50 7.3 7.3 7.3 ChEMBL