CHEMBL272035


SMILES Cc1c(C(=O)NCc2ccc(Cl)c(Cl)c2)nn(-c2ccc(Cl)c(Cl)c2)c1-n1cccc1
InChIKey FJOMFDMZEGTXGE-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 492.0

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CB2 CNR2 Human Cannabinoid A pKi 6.82 6.82 6.82 ChEMBL
CB1 CNR1 Human Cannabinoid A pKi 7.46 7.46 7.46 ChEMBL
CB1 CNR1 Human Cannabinoid A pKi 7.46 7.46 7.46 PDSP Ki database
CB2 CNR2 Human Cannabinoid A pKi 6.82 6.82 6.82 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CB2 CNR2 Human Cannabinoid A pIC50 6.72 6.72 6.72 ChEMBL
CB1 CNR1 Human Cannabinoid A pIC50 7.21 7.21 7.21 ChEMBL