peptide YY


SMILES None
InChIKey IXMRLEGHWROJAA-HDTKZREISA-N
Sequence YPAKPEAPGEDASPEELSRYYASLRHYLNLVTRQRY

Chemical properties

Hydrogen bond acceptors None
Hydrogen bond donors None
Rotatable bonds None
Molecular weight (Da)

Drug properties

Molecular type Peptide
Physiological/Surrogate Endogenous
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Y5 NPY5R Human Neuropeptide Y A pKi 8.9 8.9 8.9 Guide to Pharmacology
Y4 NPY4R Rat Neuropeptide Y A pKi 6.3 6.85 8.5 Guide to Pharmacology
Y5 NPY5R Rat Neuropeptide Y A pKi 9.0 9.0 9.0 Guide to Pharmacology
Y2 Q9ERC0 Rat Neuropeptide Y A pKi 10.0 10.0 10.0 Guide to Pharmacology
Y1 NPY1R Rat Neuropeptide Y A pKi 10.2 10.2 10.2 Guide to Pharmacology
Y2 NPY2R Human Neuropeptide Y A pKi 9.5 9.5 9.5 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Y4 NPY4R Mouse Neuropeptide Y A pIC50 6.3 7.4 8.5 Guide to Pharmacology
Y2 Q9ERC0 Rat Neuropeptide Y A pIC50 9.85 9.85 9.85 ChEMBL
Y2 NPY2R Human Neuropeptide Y A pIC50 10.15 10.15 10.15 ChEMBL
Y1 NPY1R Human Neuropeptide Y A pIC50 10.7 10.7 10.7 ChEMBL