Ethylketocyclazocine


SMILES CC[C@@]12CCN(CC3CC3)C(C(=O)c3ccc(O)cc31)[C@@H]2C
InChIKey SEJUQQOPVAUETF-BKBNBNODSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 299.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections


Bioactivity

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Guinea pig Opioid A pKi 7.14 9.05 9.77 ChEMBL
δ OPRD Human Opioid A pKi 5.89 8.21 8.96 ChEMBL
κ OPRK Human Opioid A pIC50 7.33 7.33 7.33 ChEMBL
κ OPRK Human Opioid A pEC50 8.96 8.96 8.96 ChEMBL
μ OPRM Human Opioid A pEC50 8.26 8.26 8.26 ChEMBL