Chembl282495

Chemical Properties

SMILES Cc1nnc2n1-c1sc(C#CCn3c(=O)c4ccccc4c4ccccc43)cc1C(c1ccccc1Cl)=NC2O
Hydrogen bond acceptors 8
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight 561.1

Drug Properties

Type Small molecule
Endogenous No
Approved No
InChIKey GTTQCZXVNFENHV-UHFFFAOYSA-N

Database Connections

External Links


Bioactivity

Receptor Experimental Data Source
GTP Uniprot Species Family Class Type Min Avg Max Database
PAF PTAFR Human Platelet-activating factor A pIC50 7.6 7.6 7.6 ChEMBL