SULTOPRIDE
SMILES | CCN1CCCC1CNC(=O)c1cc(S(=O)(=O)CC)ccc1OC |
InChIKey | UNRHXEPDKXPRTM-UHFFFAOYSA-N |
Chemical properties
Hydrogen bond acceptors | 5 |
Hydrogen bond donors | 1 |
Rotatable bonds | 7 |
Molecular weight (Da) | 354.2 |
Drug properties
Molecular type | Small molecule |
Endogenous/Surrogate | Surrogate |
Approved drug | No |
Database connections
Ligand site mutations | D2 |
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
D3 | DRD3 | Human | Dopamine | A | pKi | 8.2 | 8.2 | 8.2 | ChEMBL |
D2 | DRD2 | Human | Dopamine | A | pKi | 8.2 | 8.2 | 8.2 | ChEMBL |
D2 | DRD2 | Rat | Dopamine | A | pKi | 8.62 | 8.62 | 8.62 | PDSP Ki database |
D3 | DRD3 | Human | Dopamine | A | pKi | 8.42 | 8.42 | 8.42 | PDSP Ki database |
D2 | DRD2 | Human | Dopamine | A | pKi | 8.35 | 8.57 | 8.8 | PDSP Ki database |
D2 | DRD2 | Human | Dopamine | A | pKi | 8.07 | 8.07 | 8.07 | Drug Central |
D3 | DRD3 | Human | Dopamine | A | pKi | 8.07 | 8.07 | 8.07 | Drug Central |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |