CHEMBL2414355


SMILES Clc1ccc(-n2cc(COCCCN3CCN(c4ccccc4)CC3)cn2)cc1
InChIKey STBLFBLDGSWOEM-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 8
Molecular weight (Da) 410.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Rat Adrenoceptors A pKi 6.4 6.4 6.4 ChEMBL
D2 DRD2 Rat Dopamine A pKi 6.1 6.1 6.1 ChEMBL
D4 DRD4 Human Dopamine A pKi 5.82 5.82 5.82 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 6.51 6.51 6.51 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.55 5.55 5.55 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database