CHEMBL28178


SMILES FC(F)(F)c1ccc2c(c1)nc(N1CCNCC1)c1cccn12
InChIKey BLPNNGLJLMTUHN-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 1
Molecular weight (Da) 320.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 7.73 7.73 7.73 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1B 5HT1B Rat 5-Hydroxytryptamine A pIC50 7.68 7.68 7.68 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pIC50 6.72 6.72 6.72 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pIC50 7.43 7.43 7.43 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pIC50 5.0 5.0 5.0 ChEMBL