CHEMBL114484


SMILES Cc1ccc(CN2CCC(n3c(O)nc4ccccc43)CC2)c(Cl)c1
InChIKey KTQASNDGWLUTPN-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 355.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pIC50 5.72 5.72 5.72 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pIC50 6.07 6.07 6.07 ChEMBL
D4 DRD4 Human Dopamine A pIC50 5.77 5.77 5.77 ChEMBL
D1 DRD1 Human Dopamine A pIC50 5.56 5.56 5.56 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pIC50 5.8 5.8 5.8 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pIC50 5.75 5.75 5.75 ChEMBL
D3 DRD3 Human Dopamine A pIC50 6.81 6.81 6.81 ChEMBL
δ OPRD Human Opioid A pIC50 5.85 5.85 5.85 ChEMBL
κ OPRK Human Opioid A pIC50 6.57 6.57 6.57 ChEMBL
D2 DRD2 Human Dopamine A pIC50 6.32 6.32 6.32 ChEMBL
μ OPRM Human Opioid A pIC50 7.8 7.8 7.8 ChEMBL