Ligand Data

Ligand

id 99936
Name CHEMBL282679
SMILES COc1ccc(-c2sc3c(c2CN(C)Cc2ccccc2)c(=O)n(-c2cccc(OC)c2)c(=O)n3Cc2c(F)cccc2F)cc1
InChIKey VJKYDSYACPUUAN-UHFFFAOYSA-N
Type small-molecule
External Links

Structure

Properties

Hydrogen bond acceptors 8
Hydrogen bond donors 0
Rotatable bonds 10
Molecular weight 639.2


Bioactivity

Receptor Affinity (nM) Potency (nM)
GTP Uniprot Species Family Class Min Avg Max Min Avg Max
GnRH1 GNRHR Human Gonadotrophin-releasing hormone A (Rhodopsin) 20.0 20.0 20.0