Ligand source activities (1 row/activity)
| Ligands (move mouse cursor over ligand name to see structure) | Receptor | Activity | Chemical information | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Sel. page | Common name |
GPCRdb ID |
Reference ligand |
Vendors |
Species |
Assay Type |
Activity Type |
Activity Relation |
Activity Value |
p-value (-log) |
Fold selectivity |
Tested GPCRs |
Assay Description |
Source |
Mol weight |
Rot Bonds |
H don |
H acc |
LogP |
Smiles |
DOI |
|
| 6120 | 1741 | None | 0 | Rat | Functional | pEC50 | = | 7.5 | 7.5 | -15 | 2 | Guide to Pharmacology | None | None | None | None | 10601261 | |||||
| 16133243 | 1715 | None | 0 | Rat | Functional | pEC50 | = | 9.8 | 9.8 | -1 | 5 | Guide to Pharmacology | None | None | None | None | 10601261 | |||||
| 3593 | 1715 | None | 0 | Rat | Functional | pEC50 | = | 9.8 | 9.8 | -1 | 5 | Guide to Pharmacology | None | None | None | None | 10601261 | |||||
| 155817484 | 1714 | None | 0 | Rat | Functional | pIC50 | = | 10.2 | 10.2 | 2 | 5 | Guide to Pharmacology | None | None | None | None | 9108306 | |||||
| 155817484 | 1714 | None | 0 | Rat | Functional | pIC50 | = | 10.2 | 10.2 | 2 | 5 | Guide to Pharmacology | None | None | None | None | 9168941 | |||||
| 6117 | 1714 | None | 0 | Rat | Functional | pIC50 | = | 10.2 | 10.2 | 2 | 5 | Guide to Pharmacology | None | None | None | None | 9108306 | |||||
| 6117 | 1714 | None | 0 | Rat | Functional | pIC50 | = | 10.2 | 10.2 | 2 | 5 | Guide to Pharmacology | None | None | None | None | 9168941 | |||||
| 6129 | 1714 | None | 0 | Rat | Functional | pIC50 | = | 10.2 | 10.2 | 2 | 5 | Guide to Pharmacology | None | None | None | None | 9108306 | |||||
| 6129 | 1714 | None | 0 | Rat | Functional | pIC50 | = | 10.2 | 10.2 | 2 | 5 | Guide to Pharmacology | None | None | None | None | 9168941 | |||||
| 101927062 | 1716 | None | 20 | Rat | Functional | pIC50 | = | 10.2 | 10.2 | 1 | 5 | Guide to Pharmacology | None | None | None | None | 9108306 | |||||
| 101927062 | 1716 | None | 20 | Rat | Functional | pIC50 | = | 10.2 | 10.2 | 1 | 5 | Guide to Pharmacology | None | None | None | None | 9168941 | |||||
| 155817445 | 1716 | None | 20 | Rat | Functional | pIC50 | = | 10.2 | 10.2 | 1 | 5 | Guide to Pharmacology | None | None | None | None | 9108306 | |||||
| 155817445 | 1716 | None | 20 | Rat | Functional | pIC50 | = | 10.2 | 10.2 | 1 | 5 | Guide to Pharmacology | None | None | None | None | 9168941 | |||||
| 16133823 | 1716 | None | 20 | Rat | Functional | pIC50 | = | 10.2 | 10.2 | 1 | 5 | Guide to Pharmacology | None | None | None | None | 9108306 | |||||
| 16133823 | 1716 | None | 20 | Rat | Functional | pIC50 | = | 10.2 | 10.2 | 1 | 5 | Guide to Pharmacology | None | None | None | None | 9168941 | |||||
| 3592 | 1716 | None | 20 | Rat | Functional | pIC50 | = | 10.2 | 10.2 | 1 | 5 | Guide to Pharmacology | None | None | None | None | 9108306 | |||||
| 3592 | 1716 | None | 20 | Rat | Functional | pIC50 | = | 10.2 | 10.2 | 1 | 5 | Guide to Pharmacology | None | None | None | None | 9168941 | |||||
| 44584852 | 1716 | None | 20 | Rat | Functional | pIC50 | = | 10.2 | 10.2 | 1 | 5 | Guide to Pharmacology | None | None | None | None | 9108306 | |||||
| 44584852 | 1716 | None | 20 | Rat | Functional | pIC50 | = | 10.2 | 10.2 | 1 | 5 | Guide to Pharmacology | None | None | None | None | 9168941 | |||||
| 6090 | 1716 | None | 20 | Rat | Functional | pIC50 | = | 10.2 | 10.2 | 1 | 5 | Guide to Pharmacology | None | None | None | None | 9108306 | |||||
| 6090 | 1716 | None | 20 | Rat | Functional | pIC50 | = | 10.2 | 10.2 | 1 | 5 | Guide to Pharmacology | None | None | None | None | 9168941 | |||||
| 91898917 | 1716 | None | 20 | Rat | Functional | pIC50 | = | 10.2 | 10.2 | 1 | 5 | Guide to Pharmacology | None | None | None | None | 9108306 | |||||
| 91898917 | 1716 | None | 20 | Rat | Functional | pIC50 | = | 10.2 | 10.2 | 1 | 5 | Guide to Pharmacology | None | None | None | None | 9168941 | |||||
| CHEMBL506553 | 1716 | None | 20 | Rat | Functional | pIC50 | = | 10.2 | 10.2 | 1 | 5 | Guide to Pharmacology | None | None | None | None | 9108306 | |||||
| CHEMBL506553 | 1716 | None | 20 | Rat | Functional | pIC50 | = | 10.2 | 10.2 | 1 | 5 | Guide to Pharmacology | None | None | None | None | 9168941 | |||||
| 3898 | 2446 | None | 0 | Human | Functional | pIC50 | = | 10.4 | 10.4 | -3 | 4 | Guide to Pharmacology | None | None | None | None | 9168941 | |||||
| 3898 | 2446 | None | 0 | Rat | Functional | pIC50 | = | 11 | 11.0 | 3 | 4 | Guide to Pharmacology | None | None | None | None | 9108306 | |||||
| 3898 | 2446 | None | 0 | Rat | Functional | pIC50 | = | 11 | 11.0 | 3 | 4 | Guide to Pharmacology | None | None | None | None | 9168941 | |||||
| 20549618 | 48 | None | 0 | Human | Functional | pIC50 | = | 5.6 | 5.6 | - | 1 | Guide to Pharmacology | 182 | 0 | 0 | 4 | -0.7 | O=S1(=O)CCS(=O)(=O)C=C1 | 10896115 | |||
| 3486 | 48 | None | 0 | Human | Functional | pIC50 | = | 5.6 | 5.6 | - | 1 | Guide to Pharmacology | 182 | 0 | 0 | 4 | -0.7 | O=S1(=O)CCS(=O)(=O)C=C1 | 10896115 | |||
| 155817474 | 1728 | None | 0 | Human | Functional | pIC50 | = | 6.1 | 6.1 | -489 | 2 | Guide to Pharmacology | None | None | None | None | 11481429 | |||||
| 5357 | 1728 | None | 0 | Human | Functional | pIC50 | = | 6.1 | 6.1 | -489 | 2 | Guide to Pharmacology | None | None | None | None | 11481429 | |||||
| 6124 | 1439 | None | 0 | Human | Functional | pIC50 | = | 6.7 | 6.7 | 158 | 2 | Guide to Pharmacology | 286 | 1 | 0 | 4 | 1.5 | Cc1ccc(cc1)C1=CS(=O)(=O)CCCS1(=O)=O | 10896115 | |||
| 9947811 | 1439 | None | 0 | Human | Functional | pIC50 | = | 6.7 | 6.7 | 158 | 2 | Guide to Pharmacology | 286 | 1 | 0 | 4 | 1.5 | Cc1ccc(cc1)C1=CS(=O)(=O)CCCS1(=O)=O | 10896115 | |||
| CHEMBL3906195 | 1439 | None | 0 | Human | Functional | pIC50 | = | 6.7 | 6.7 | 158 | 2 | Guide to Pharmacology | 286 | 1 | 0 | 4 | 1.5 | Cc1ccc(cc1)C1=CS(=O)(=O)CCCS1(=O)=O | 10896115 | |||
| 155817485 | 1757 | None | 0 | Human | Functional | pIC50 | = | 6.9 | 6.9 | -1 | 2 | Guide to Pharmacology | None | None | None | None | 15944009 | |||||
| 6121 | 1757 | None | 0 | Human | Functional | pIC50 | = | 6.9 | 6.9 | -1 | 2 | Guide to Pharmacology | None | None | None | None | 15944009 | |||||
| 3594 | 1742 | None | 0 | Human | Functional | pIC50 | = | 7.1 | 7.1 | -7 | 3 | Guide to Pharmacology | None | None | None | None | 15944009 | |||||
| 3596 | 1740 | None | 0 | Rat | Functional | pIC50 | = | 7.4 | 7.4 | -29 | 2 | Guide to Pharmacology | None | None | None | None | 20880399 | |||||
| 134813891 | 1758 | None | 0 | Human | Functional | pIC50 | = | 7.5 | 7.5 | -2 | 2 | Guide to Pharmacology | None | None | None | None | 15944009 | |||||
| 6122 | 1758 | None | 0 | Human | Functional | pIC50 | = | 7.5 | 7.5 | -2 | 2 | Guide to Pharmacology | None | None | None | None | 15944009 | |||||
| 155817487 | 1729 | None | 0 | Human | Functional | pIC50 | = | 7.5 | 7.5 | -9 | 2 | Guide to Pharmacology | None | None | None | None | 9685625 | |||||
| 6130 | 1729 | None | 0 | Human | Functional | pIC50 | = | 7.5 | 7.5 | -9 | 2 | Guide to Pharmacology | None | None | None | None | 9685625 | |||||
| 155817465 | 1730 | None | 0 | Human | Functional | pIC50 | = | 8 | 8.0 | -3 | 3 | Guide to Pharmacology | None | None | None | None | 9168941 | |||||
| 3876 | 1730 | None | 0 | Human | Functional | pIC50 | = | 8 | 8.0 | -3 | 3 | Guide to Pharmacology | None | None | None | None | 9168941 | |||||
| 155817465 | 1730 | None | 0 | Rat | Functional | pIC50 | = | 8.1 | 8.1 | -2 | 3 | Guide to Pharmacology | None | None | None | None | 9108306 | |||||
| 155817465 | 1730 | None | 0 | Rat | Functional | pIC50 | = | 8.1 | 8.1 | -2 | 3 | Guide to Pharmacology | None | None | None | None | 9168941 | |||||
| 3876 | 1730 | None | 0 | Rat | Functional | pIC50 | = | 8.1 | 8.1 | -2 | 3 | Guide to Pharmacology | None | None | None | None | 9108306 | |||||
| 3876 | 1730 | None | 0 | Rat | Functional | pIC50 | = | 8.1 | 8.1 | -2 | 3 | Guide to Pharmacology | None | None | None | None | 9168941 | |||||
| 155817463 | 777 | None | 0 | Rat | Functional | pIC50 | = | 8.3 | 8.3 | -1 | 4 | Guide to Pharmacology | None | None | None | None | 9108306 | |||||
| 155817463 | 777 | None | 0 | Rat | Functional | pIC50 | = | 8.3 | 8.3 | -1 | 4 | Guide to Pharmacology | None | None | None | None | 9168941 | |||||
| 3861 | 777 | None | 0 | Rat | Functional | pIC50 | = | 8.3 | 8.3 | -1 | 4 | Guide to Pharmacology | None | None | None | None | 9108306 | |||||
| 3861 | 777 | None | 0 | Rat | Functional | pIC50 | = | 8.3 | 8.3 | -1 | 4 | Guide to Pharmacology | None | None | None | None | 9168941 | |||||
| 6120 | 1741 | None | 0 | Rat | Functional | pIC50 | = | 8.4 | 8.4 | -15 | 2 | Guide to Pharmacology | None | None | None | None | 10601261 | |||||
| 155817463 | 777 | None | 0 | Human | Functional | pIC50 | = | 8.6 | 8.6 | 1 | 4 | Guide to Pharmacology | None | None | None | None | 9168941 | |||||
| 155817463 | 777 | None | 0 | Human | Functional | pIC50 | = | 8.6 | 8.6 | 1 | 4 | Guide to Pharmacology | None | None | None | None | 9685625 | |||||
| 3861 | 777 | None | 0 | Human | Functional | pIC50 | = | 8.6 | 8.6 | 1 | 4 | Guide to Pharmacology | None | None | None | None | 9168941 | |||||
| 3861 | 777 | None | 0 | Human | Functional | pIC50 | = | 8.6 | 8.6 | 1 | 4 | Guide to Pharmacology | None | None | None | None | 9685625 | |||||
| 16131409 | 1723 | None | 0 | Human | Functional | pIC50 | = | 8.8 | 8.8 | -1 | 3 | Guide to Pharmacology | None | None | None | None | 9685625 | |||||
| 6086 | 1723 | None | 0 | Human | Functional | pIC50 | = | 8.8 | 8.8 | -1 | 3 | Guide to Pharmacology | None | None | None | None | 9685625 | |||||
| 3896 | 2443 | None | 0 | Human | Functional | pIC50 | = | 8.8 | 8.8 | -1 | 4 | Guide to Pharmacology | None | None | None | None | 9168941 | |||||
| 3896 | 2443 | None | 0 | Human | Functional | pIC50 | = | 8.8 | 8.8 | -1 | 4 | Guide to Pharmacology | None | None | None | None | 9685625 | |||||
| 155817473 | 1720 | None | 0 | Human | Functional | pIC50 | = | 9.0 | 9.0 | 1 | 2 | Guide to Pharmacology | None | None | None | None | 11481429 | |||||
| 5356 | 1720 | None | 0 | Human | Functional | pIC50 | = | 9.0 | 9.0 | 1 | 2 | Guide to Pharmacology | None | None | None | None | 11481429 | |||||
| 6084 | 1720 | None | 0 | Human | Functional | pIC50 | = | 9.0 | 9.0 | 1 | 2 | Guide to Pharmacology | None | None | None | None | 11481429 | |||||
| 3896 | 2443 | None | 0 | Rat | Functional | pIC50 | = | 9 | 9.0 | 1 | 4 | Guide to Pharmacology | None | None | None | None | 9108306 | |||||
| 3896 | 2443 | None | 0 | Rat | Functional | pIC50 | = | 9 | 9.0 | 1 | 4 | Guide to Pharmacology | None | None | None | None | 9168941 | |||||
| 3899 | 2447 | None | 0 | Rat | Functional | pIC50 | = | 9.1 | 9.1 | -1 | 4 | Guide to Pharmacology | None | None | None | None | 9108306 | |||||
| 3899 | 2447 | None | 0 | Rat | Functional | pIC50 | = | 9.1 | 9.1 | -1 | 4 | Guide to Pharmacology | None | None | None | None | 9168941 | |||||
| 16132180 | 1724 | None | 20 | Human | Functional | pIC50 | = | 9.1 | 9.1 | -2 | 4 | Guide to Pharmacology | None | None | None | None | 9168941 | |||||
| 16132180 | 1724 | None | 20 | Human | Functional | pIC50 | = | 9.1 | 9.1 | -2 | 4 | Guide to Pharmacology | None | None | None | None | 9685625 | |||||
| 16133822 | 1724 | None | 20 | Human | Functional | pIC50 | = | 9.1 | 9.1 | -2 | 4 | Guide to Pharmacology | None | None | None | None | 9168941 | |||||
| 16133822 | 1724 | None | 20 | Human | Functional | pIC50 | = | 9.1 | 9.1 | -2 | 4 | Guide to Pharmacology | None | None | None | None | 9685625 | |||||
| 6087 | 1724 | None | 20 | Human | Functional | pIC50 | = | 9.1 | 9.1 | -2 | 4 | Guide to Pharmacology | None | None | None | None | 9168941 | |||||
| 6087 | 1724 | None | 20 | Human | Functional | pIC50 | = | 9.1 | 9.1 | -2 | 4 | Guide to Pharmacology | None | None | None | None | 9685625 | |||||
| CHEMBL499980 | 1724 | None | 20 | Human | Functional | pIC50 | = | 9.1 | 9.1 | -2 | 4 | Guide to Pharmacology | None | None | None | None | 9168941 | |||||
| CHEMBL499980 | 1724 | None | 20 | Human | Functional | pIC50 | = | 9.1 | 9.1 | -2 | 4 | Guide to Pharmacology | None | None | None | None | 9685625 | |||||
| 3899 | 2447 | None | 0 | Human | Functional | pIC50 | = | 9.3 | 9.3 | 1 | 4 | Guide to Pharmacology | None | None | None | None | 9168941 | |||||
| 6082 | 3482 | None | 0 | Human | Functional | pIC50 | = | 9.4 | 9.4 | 4 | 2 | Guide to Pharmacology | None | None | None | None | 11491429 | |||||
| 16133243 | 1715 | None | 0 | Rat | Functional | pIC50 | = | 9.4 | 9.4 | -1 | 5 | Guide to Pharmacology | None | None | None | None | 10601261 | |||||
| 16133243 | 1715 | None | 0 | Rat | Functional | pIC50 | = | 9.4 | 9.4 | -1 | 5 | Guide to Pharmacology | None | None | None | None | 20880399 | |||||
| 3593 | 1715 | None | 0 | Rat | Functional | pIC50 | = | 9.4 | 9.4 | -1 | 5 | Guide to Pharmacology | None | None | None | None | 10601261 | |||||
| 3593 | 1715 | None | 0 | Rat | Functional | pIC50 | = | 9.4 | 9.4 | -1 | 5 | Guide to Pharmacology | None | None | None | None | 20880399 | |||||
| 6088 | 1725 | None | 0 | Human | Functional | pIC50 | = | 9.5 | 9.5 | -2 | 2 | Guide to Pharmacology | None | None | None | None | 9168941 | |||||
| 90469849 | 1725 | None | 0 | Human | Functional | pIC50 | = | 9.5 | 9.5 | -2 | 2 | Guide to Pharmacology | None | None | None | None | 9168941 | |||||
| 16132180 | 1724 | None | 20 | Rat | Functional | pIC50 | = | 9.6 | 9.6 | 2 | 4 | Guide to Pharmacology | None | None | None | None | 9108306 | |||||
| 16132180 | 1724 | None | 20 | Rat | Functional | pIC50 | = | 9.6 | 9.6 | 2 | 4 | Guide to Pharmacology | None | None | None | None | 9168941 | |||||
| 16133822 | 1724 | None | 20 | Rat | Functional | pIC50 | = | 9.6 | 9.6 | 2 | 4 | Guide to Pharmacology | None | None | None | None | 9108306 | |||||
| 16133822 | 1724 | None | 20 | Rat | Functional | pIC50 | = | 9.6 | 9.6 | 2 | 4 | Guide to Pharmacology | None | None | None | None | 9168941 | |||||
| 6087 | 1724 | None | 20 | Rat | Functional | pIC50 | = | 9.6 | 9.6 | 2 | 4 | Guide to Pharmacology | None | None | None | None | 9108306 | |||||
| 6087 | 1724 | None | 20 | Rat | Functional | pIC50 | = | 9.6 | 9.6 | 2 | 4 | Guide to Pharmacology | None | None | None | None | 9168941 | |||||
| CHEMBL499980 | 1724 | None | 20 | Rat | Functional | pIC50 | = | 9.6 | 9.6 | 2 | 4 | Guide to Pharmacology | None | None | None | None | 9108306 | |||||
| CHEMBL499980 | 1724 | None | 20 | Rat | Functional | pIC50 | = | 9.6 | 9.6 | 2 | 4 | Guide to Pharmacology | None | None | None | None | 9168941 | |||||
| 101927062 | 1716 | None | 20 | Human | Functional | pIC50 | = | 9.7 | 9.7 | -1 | 5 | Guide to Pharmacology | None | None | None | None | 11481429 | |||||
| 101927062 | 1716 | None | 20 | Human | Functional | pIC50 | = | 9.7 | 9.7 | -1 | 5 | Guide to Pharmacology | None | None | None | None | 9168941 | |||||
| 101927062 | 1716 | None | 20 | Human | Functional | pIC50 | = | 9.7 | 9.7 | -1 | 5 | Guide to Pharmacology | None | None | None | None | 9685625 | |||||
| 155817445 | 1716 | None | 20 | Human | Functional | pIC50 | = | 9.7 | 9.7 | -1 | 5 | Guide to Pharmacology | None | None | None | None | 11481429 | |||||
| 155817445 | 1716 | None | 20 | Human | Functional | pIC50 | = | 9.7 | 9.7 | -1 | 5 | Guide to Pharmacology | None | None | None | None | 9168941 | |||||
| 155817445 | 1716 | None | 20 | Human | Functional | pIC50 | = | 9.7 | 9.7 | -1 | 5 | Guide to Pharmacology | None | None | None | None | 9685625 | |||||
| 16133823 | 1716 | None | 20 | Human | Functional | pIC50 | = | 9.7 | 9.7 | -1 | 5 | Guide to Pharmacology | None | None | None | None | 11481429 | |||||
| 16133823 | 1716 | None | 20 | Human | Functional | pIC50 | = | 9.7 | 9.7 | -1 | 5 | Guide to Pharmacology | None | None | None | None | 9168941 | |||||
| 16133823 | 1716 | None | 20 | Human | Functional | pIC50 | = | 9.7 | 9.7 | -1 | 5 | Guide to Pharmacology | None | None | None | None | 9685625 | |||||
| 3592 | 1716 | None | 20 | Human | Functional | pIC50 | = | 9.7 | 9.7 | -1 | 5 | Guide to Pharmacology | None | None | None | None | 11481429 | |||||
| 3592 | 1716 | None | 20 | Human | Functional | pIC50 | = | 9.7 | 9.7 | -1 | 5 | Guide to Pharmacology | None | None | None | None | 9168941 | |||||
| 3592 | 1716 | None | 20 | Human | Functional | pIC50 | = | 9.7 | 9.7 | -1 | 5 | Guide to Pharmacology | None | None | None | None | 9685625 | |||||
| 44584852 | 1716 | None | 20 | Human | Functional | pIC50 | = | 9.7 | 9.7 | -1 | 5 | Guide to Pharmacology | None | None | None | None | 11481429 | |||||
| 44584852 | 1716 | None | 20 | Human | Functional | pIC50 | = | 9.7 | 9.7 | -1 | 5 | Guide to Pharmacology | None | None | None | None | 9168941 | |||||
| 44584852 | 1716 | None | 20 | Human | Functional | pIC50 | = | 9.7 | 9.7 | -1 | 5 | Guide to Pharmacology | None | None | None | None | 9685625 | |||||
| 6090 | 1716 | None | 20 | Human | Functional | pIC50 | = | 9.7 | 9.7 | -1 | 5 | Guide to Pharmacology | None | None | None | None | 11481429 | |||||
| 6090 | 1716 | None | 20 | Human | Functional | pIC50 | = | 9.7 | 9.7 | -1 | 5 | Guide to Pharmacology | None | None | None | None | 9168941 | |||||
| 6090 | 1716 | None | 20 | Human | Functional | pIC50 | = | 9.7 | 9.7 | -1 | 5 | Guide to Pharmacology | None | None | None | None | 9685625 | |||||
| 91898917 | 1716 | None | 20 | Human | Functional | pIC50 | = | 9.7 | 9.7 | -1 | 5 | Guide to Pharmacology | None | None | None | None | 11481429 | |||||
| 91898917 | 1716 | None | 20 | Human | Functional | pIC50 | = | 9.7 | 9.7 | -1 | 5 | Guide to Pharmacology | None | None | None | None | 9168941 | |||||
| 91898917 | 1716 | None | 20 | Human | Functional | pIC50 | = | 9.7 | 9.7 | -1 | 5 | Guide to Pharmacology | None | None | None | None | 9685625 | |||||
| CHEMBL506553 | 1716 | None | 20 | Human | Functional | pIC50 | = | 9.7 | 9.7 | -1 | 5 | Guide to Pharmacology | None | None | None | None | 11481429 | |||||
| CHEMBL506553 | 1716 | None | 20 | Human | Functional | pIC50 | = | 9.7 | 9.7 | -1 | 5 | Guide to Pharmacology | None | None | None | None | 9168941 | |||||
| CHEMBL506553 | 1716 | None | 20 | Human | Functional | pIC50 | = | 9.7 | 9.7 | -1 | 5 | Guide to Pharmacology | None | None | None | None | 9685625 | |||||
| 155817484 | 1714 | None | 0 | Human | Functional | pIC50 | = | 9.8 | 9.8 | -2 | 5 | Guide to Pharmacology | None | None | None | None | 9168941 | |||||
| 155817484 | 1714 | None | 0 | Human | Functional | pIC50 | = | 9.8 | 9.8 | -2 | 5 | Guide to Pharmacology | None | None | None | None | 9685625 | |||||
| 6117 | 1714 | None | 0 | Human | Functional | pIC50 | = | 9.8 | 9.8 | -2 | 5 | Guide to Pharmacology | None | None | None | None | 9168941 | |||||
| 6117 | 1714 | None | 0 | Human | Functional | pIC50 | = | 9.8 | 9.8 | -2 | 5 | Guide to Pharmacology | None | None | None | None | 9685625 | |||||
| 6129 | 1714 | None | 0 | Human | Functional | pIC50 | = | 9.8 | 9.8 | -2 | 5 | Guide to Pharmacology | None | None | None | None | 9168941 | |||||
| 6129 | 1714 | None | 0 | Human | Functional | pIC50 | = | 9.8 | 9.8 | -2 | 5 | Guide to Pharmacology | None | None | None | None | 9685625 | |||||
| 6088 | 1725 | None | 0 | Rat | Functional | pIC50 | = | 9.8 | 9.8 | 2 | 2 | Guide to Pharmacology | None | None | None | None | 9168941 | |||||
| 90469849 | 1725 | None | 0 | Rat | Functional | pIC50 | = | 9.8 | 9.8 | 2 | 2 | Guide to Pharmacology | None | None | None | None | 9168941 | |||||
| 16133243 | 1715 | None | 0 | Human | Functional | pIC50 | = | 9.9 | 9.9 | 1 | 5 | Guide to Pharmacology | None | None | None | None | 9685625 | |||||
| 3593 | 1715 | None | 0 | Human | Functional | pIC50 | = | 9.9 | 9.9 | 1 | 5 | Guide to Pharmacology | None | None | None | None | 9685625 | |||||
| 131863305 | 327 | None | 0 | Rat | Functional | pIC50 | > | 6 | 6.0 | -1 | 3 | Guide to Pharmacology | None | None | None | None | 20880399 | |||||
| 155817486 | 327 | None | 0 | Rat | Functional | pIC50 | > | 6 | 6.0 | -1 | 3 | Guide to Pharmacology | None | None | None | None | 20880399 | |||||
| 6123 | 327 | None | 0 | Rat | Functional | pIC50 | > | 6 | 6.0 | -1 | 3 | Guide to Pharmacology | None | None | None | None | 20880399 | |||||
| 155817480 | 1731 | None | 0 | Human | Functional | pIC50 | > | 6 | 6.0 | 1 | 3 | Guide to Pharmacology | None | None | None | None | 9685625 | |||||
| 6091 | 1731 | None | 0 | Human | Functional | pIC50 | > | 6 | 6.0 | 1 | 3 | Guide to Pharmacology | None | None | None | None | 9685625 | |||||
| 155817481 | 1732 | None | 0 | Human | Functional | pIC50 | > | 6 | 6.0 | 1 | 3 | Guide to Pharmacology | None | None | None | None | 9168941 | |||||
| 155817481 | 1732 | None | 0 | Rat | Functional | pIC50 | > | 6 | 6.0 | -1 | 3 | Guide to Pharmacology | None | None | None | None | 9108306 | |||||
| 155817481 | 1732 | None | 0 | Rat | Functional | pIC50 | > | 6 | 6.0 | -1 | 3 | Guide to Pharmacology | None | None | None | None | 9168941 | |||||
| 6092 | 1732 | None | 0 | Human | Functional | pIC50 | > | 6 | 6.0 | 1 | 3 | Guide to Pharmacology | None | None | None | None | 9168941 | |||||
| 6092 | 1732 | None | 0 | Rat | Functional | pIC50 | > | 6 | 6.0 | -1 | 3 | Guide to Pharmacology | None | None | None | None | 9108306 | |||||
| 6092 | 1732 | None | 0 | Rat | Functional | pIC50 | > | 6 | 6.0 | -1 | 3 | Guide to Pharmacology | None | None | None | None | 9168941 | |||||
| Ligands (move mouse cursor over ligand name to see structure) | Receptor | Activity | Chemical information | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Sel. page | Common name |
GPCRdb ID |
Reference ligand |
Vendors |
Species |
Assay Type |
Activity Type |
Activity Relation |
Activity Value |
p-value (-log) |
Fold selectivity |
Tested GPCRs |
Assay Description |
Source |
Mol weight |
Rot Bonds |
H don |
H acc |
LogP |
Smiles |
DOI |
|
| 101927062 | 1716 | None | 20 | Human | Binding | pIC50 | = | 10.1 | 10.1 | -10 | 6 | ChEMBL | None | None | None | None | 10.1016/j.bmc.2016.11.014 | |||||
| 155817445 | 1716 | None | 20 | Human | Binding | pIC50 | = | 10.1 | 10.1 | -10 | 6 | ChEMBL | None | None | None | None | 10.1016/j.bmc.2016.11.014 | |||||
| 16133823 | 1716 | None | 20 | Human | Binding | pIC50 | = | 10.1 | 10.1 | -10 | 6 | ChEMBL | None | None | None | None | 10.1016/j.bmc.2016.11.014 | |||||
| 3592 | 1716 | None | 20 | Human | Binding | pIC50 | = | 10.1 | 10.1 | -10 | 6 | ChEMBL | None | None | None | None | 10.1016/j.bmc.2016.11.014 | |||||
| 44584852 | 1716 | None | 20 | Human | Binding | pIC50 | = | 10.1 | 10.1 | -10 | 6 | ChEMBL | None | None | None | None | 10.1016/j.bmc.2016.11.014 | |||||
| 6090 | 1716 | None | 20 | Human | Binding | pIC50 | = | 10.1 | 10.1 | -10 | 6 | ChEMBL | None | None | None | None | 10.1016/j.bmc.2016.11.014 | |||||
| 91898917 | 1716 | None | 20 | Human | Binding | pIC50 | = | 10.1 | 10.1 | -10 | 6 | ChEMBL | None | None | None | None | 10.1016/j.bmc.2016.11.014 | |||||
| CHEMBL506553 | 1716 | None | 20 | Human | Binding | pIC50 | = | 10.1 | 10.1 | -10 | 6 | ChEMBL | None | None | None | None | 10.1016/j.bmc.2016.11.014 | |||||
| CHEMBL501079 | 216618 | None | 9 | Human | Binding | pIC50 | = | 9.8 | 9.8 | 11 | 2 | ChEMBL | None | None | None | CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CN)[C@@H](C)O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(N)=O | 10.1016/j.bmc.2013.03.016 | |||||
| CHEMBL501079 | 216618 | None | 9 | Human | Binding | pIC50 | = | 9.1 | 9.1 | 11 | 2 | ChEMBL | None | None | None | CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CN)[C@@H](C)O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(N)=O | 10.1016/j.ejmech.2013.01.044 | |||||
| CHEMBL501079 | 216618 | None | 9 | Human | Binding | pIC50 | = | 9.1 | 9.1 | 11 | 2 | ChEMBL | None | None | None | CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CN)[C@@H](C)O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(N)=O | 10.1021/jm8007618 | |||||
| CHEMBL473840 | 216514 | None | 0 | Rat | Binding | pIC50 | = | 8.0 | 8.0 | - | 0 | ChEMBL | None | None | None | CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@H](C)[C@@H](C)O)NC(=O)[C@H](C(C)C)NC1=O | 10.1016/j.bmcl.2008.10.104 | |||||
| 134142691 | 145784 | None | 0 | Human | Binding | pIC50 | = | 6 | 6.0 | - | 0 | ChEMBL | 344 | 3 | 0 | 6 | 1.4 | CCOC(=O)c1cccc(C2=CS(=O)(=O)CCCS2(=O)=O)c1 | nan | |||
| CHEMBL3916206 | 145784 | None | 0 | Human | Binding | pIC50 | = | 6 | 6.0 | - | 0 | ChEMBL | 344 | 3 | 0 | 6 | 1.4 | CCOC(=O)c1cccc(C2=CS(=O)(=O)CCCS2(=O)=O)c1 | nan | |||
| 101061658 | 148670 | None | 0 | Human | Binding | pIC50 | = | 6 | 6.0 | - | 0 | ChEMBL | 302 | 2 | 0 | 5 | 1.2 | COc1ccccc1C1=CS(=O)(=O)CCCS1(=O)=O | nan | |||
| CHEMBL3939021 | 148670 | None | 0 | Human | Binding | pIC50 | = | 6 | 6.0 | - | 0 | ChEMBL | 302 | 2 | 0 | 5 | 1.2 | COc1ccccc1C1=CS(=O)(=O)CCCS1(=O)=O | nan | |||
| 12043584 | 150886 | None | 0 | Human | Binding | pIC50 | = | 6 | 6.0 | - | 0 | ChEMBL | 336 | 1 | 0 | 4 | 1.6 | O=S1(=O)C=C(c2ccc(Br)cc2)S(=O)(=O)CC1 | nan | |||
| CHEMBL3956728 | 150886 | None | 0 | Human | Binding | pIC50 | = | 6 | 6.0 | - | 0 | ChEMBL | 336 | 1 | 0 | 4 | 1.6 | O=S1(=O)C=C(c2ccc(Br)cc2)S(=O)(=O)CC1 | nan | |||
| 134155181 | 151479 | None | 0 | Human | Binding | pIC50 | = | 6 | 6.0 | - | 0 | ChEMBL | 477 | 9 | 1 | 6 | 2.9 | CCCCOc1ccccc1C(=O)NC(Cc1ccccc1)C1=CS(=O)(=O)CCS1(=O)=O | nan | |||
| CHEMBL3961540 | 151479 | None | 0 | Human | Binding | pIC50 | = | 6 | 6.0 | - | 0 | ChEMBL | 477 | 9 | 1 | 6 | 2.9 | CCCCOc1ccccc1C(=O)NC(Cc1ccccc1)C1=CS(=O)(=O)CCS1(=O)=O | nan | |||
| 9861375 | 153346 | None | 0 | Human | Binding | pIC50 | = | 6 | 6.0 | - | 0 | ChEMBL | 306 | 1 | 0 | 4 | 1.9 | O=S1(=O)C=C(c2cccc(Cl)c2)S(=O)(=O)CCC1 | nan | |||
| CHEMBL3977579 | 153346 | None | 0 | Human | Binding | pIC50 | = | 6 | 6.0 | - | 0 | ChEMBL | 306 | 1 | 0 | 4 | 1.9 | O=S1(=O)C=C(c2cccc(Cl)c2)S(=O)(=O)CCC1 | nan | |||
| 90721869 | 150436 | None | 0 | Human | Binding | pIC50 | = | 6.0 | 6.0 | - | 0 | ChEMBL | 357 | 4 | 1 | 5 | 1.4 | CCCNC(=O)c1ccc(C2=CS(=O)(=O)CCCS2(=O)=O)cc1 | nan | |||
| CHEMBL3953131 | 150436 | None | 0 | Human | Binding | pIC50 | = | 6.0 | 6.0 | - | 0 | ChEMBL | 357 | 4 | 1 | 5 | 1.4 | CCCNC(=O)c1ccc(C2=CS(=O)(=O)CCCS2(=O)=O)cc1 | nan | |||
| 134142161 | 145671 | None | 0 | Human | Binding | pIC50 | = | 6.0 | 6.0 | - | 0 | ChEMBL | 419 | 5 | 1 | 5 | 2.2 | O=C(NCCc1ccccc1)c1ccc(C2=CS(=O)(=O)CCCS2(=O)=O)cc1 | nan | |||
| CHEMBL3915361 | 145671 | None | 0 | Human | Binding | pIC50 | = | 6.0 | 6.0 | - | 0 | ChEMBL | 419 | 5 | 1 | 5 | 2.2 | O=C(NCCc1ccccc1)c1ccc(C2=CS(=O)(=O)CCCS2(=O)=O)cc1 | nan | |||
| CHEMBL474038 | 216516 | None | 0 | Rat | Binding | pIC50 | = | 8.0 | 8.0 | - | 0 | ChEMBL | None | None | None | CC(C)[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@H](C)[C@@H](C)O)NC(=O)[C@H](C(C)C)NC1=O | 10.1016/j.bmcl.2008.10.104 | |||||
| CHEMBL474037 | 216515 | None | 0 | Rat | Binding | pIC50 | = | 7.9 | 7.9 | - | 0 | ChEMBL | None | None | None | CC[C@H](C)[C@@H]1NC(=O)[C@H](C(C)C)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@H](C)[C@@H](C)O)NC1=O | 10.1016/j.bmcl.2008.10.104 | |||||
| 91480105 | 153622 | None | 0 | Human | Binding | pIC50 | = | 6.0 | 6.0 | - | 0 | ChEMBL | 354 | 2 | 0 | 4 | 3.3 | O=S1(=O)C=C(c2ccc(C3CCCCC3)cc2)S(=O)(=O)CCC1 | nan | |||
| CHEMBL3980007 | 153622 | None | 0 | Human | Binding | pIC50 | = | 6.0 | 6.0 | - | 0 | ChEMBL | 354 | 2 | 0 | 4 | 3.3 | O=S1(=O)C=C(c2ccc(C3CCCCC3)cc2)S(=O)(=O)CCC1 | nan | |||
| 57399456 | 68821 | None | 0 | Human | Binding | pIC50 | = | 4.9 | 4.9 | - | 0 | ChEMBL | 430 | 6 | 1 | 7 | 4.2 | COc1ccc(Nc2cc(N3CCN(c4ccccc4)CC3)nc(N3CCCC3)n2)cc1 | 10.1016/j.bmcl.2011.09.033 | |||
| CHEMBL1921992 | 68821 | None | 0 | Human | Binding | pIC50 | = | 4.9 | 4.9 | - | 0 | ChEMBL | 430 | 6 | 1 | 7 | 4.2 | COc1ccc(Nc2cc(N3CCN(c4ccccc4)CC3)nc(N3CCCC3)n2)cc1 | 10.1016/j.bmcl.2011.09.033 | |||
| 57394238 | 68833 | None | 0 | Human | Binding | pIC50 | = | 5.9 | 5.9 | - | 0 | ChEMBL | 529 | 5 | 1 | 7 | 5.8 | Cc1c(F)cccc1Nc1cc(N2CCCCC2)nc(N2CCCN(c3ncccc3C(F)(F)F)CC2)n1 | 10.1016/j.bmcl.2011.09.033 | |||
| CHEMBL1922003 | 68833 | None | 0 | Human | Binding | pIC50 | = | 5.9 | 5.9 | - | 0 | ChEMBL | 529 | 5 | 1 | 7 | 5.8 | Cc1c(F)cccc1Nc1cc(N2CCCCC2)nc(N2CCCN(c3ncccc3C(F)(F)F)CC2)n1 | 10.1016/j.bmcl.2011.09.033 | |||
| 9925905 | 145035 | None | 0 | Human | Binding | pIC50 | = | 5.9 | 5.9 | - | 0 | ChEMBL | 286 | 1 | 0 | 4 | 1.5 | Cc1cccc(C2=CS(=O)(=O)CCCS2(=O)=O)c1 | nan | |||
| CHEMBL3910434 | 145035 | None | 0 | Human | Binding | pIC50 | = | 5.9 | 5.9 | - | 0 | ChEMBL | 286 | 1 | 0 | 4 | 1.5 | Cc1cccc(C2=CS(=O)(=O)CCCS2(=O)=O)c1 | nan | |||
| 9796013 | 146050 | None | 0 | Human | Binding | pIC50 | = | 5.9 | 5.9 | - | 0 | ChEMBL | 290 | 1 | 0 | 4 | 1.4 | O=S1(=O)C=C(c2cccc(F)c2)S(=O)(=O)CCC1 | nan | |||
| CHEMBL3918185 | 146050 | None | 0 | Human | Binding | pIC50 | = | 5.9 | 5.9 | - | 0 | ChEMBL | 290 | 1 | 0 | 4 | 1.4 | O=S1(=O)C=C(c2cccc(F)c2)S(=O)(=O)CCC1 | nan | |||
| 57008825 | 152917 | None | 0 | Human | Binding | pIC50 | = | 5.9 | 5.9 | - | 0 | ChEMBL | 278 | 1 | 0 | 5 | 1.3 | O=S1(=O)C=C(c2cccs2)S(=O)(=O)CCC1 | nan | |||
| CHEMBL3973948 | 152917 | None | 0 | Human | Binding | pIC50 | = | 5.9 | 5.9 | - | 0 | ChEMBL | 278 | 1 | 0 | 5 | 1.3 | O=S1(=O)C=C(c2cccs2)S(=O)(=O)CCC1 | nan | |||
| 101061657 | 153207 | None | 0 | Human | Binding | pIC50 | = | 5.9 | 5.9 | - | 0 | ChEMBL | 278 | 1 | 0 | 5 | 1.3 | O=S1(=O)C=C(c2ccsc2)S(=O)(=O)CCC1 | nan | |||
| CHEMBL3976401 | 153207 | None | 0 | Human | Binding | pIC50 | = | 5.9 | 5.9 | - | 0 | ChEMBL | 278 | 1 | 0 | 5 | 1.3 | O=S1(=O)C=C(c2ccsc2)S(=O)(=O)CCC1 | nan | |||
| 91376438 | 144206 | None | 0 | Human | Binding | pIC50 | = | 5.8 | 5.8 | - | 0 | ChEMBL | 412 | 3 | 0 | 6 | 2.1 | O=S1(=O)C=C(c2ccc(S(=O)(=O)c3ccccc3)cc2)S(=O)(=O)CCC1 | nan | |||
| CHEMBL3903668 | 144206 | None | 0 | Human | Binding | pIC50 | = | 5.8 | 5.8 | - | 0 | ChEMBL | 412 | 3 | 0 | 6 | 2.1 | O=S1(=O)C=C(c2ccc(S(=O)(=O)c3ccccc3)cc2)S(=O)(=O)CCC1 | nan | |||
| 91000662 | 150767 | None | 0 | Human | Binding | pIC50 | = | 5.8 | 5.8 | - | 0 | ChEMBL | 286 | 1 | 0 | 4 | 1.5 | Cc1ccccc1C1=CS(=O)(=O)CCCS1(=O)=O | nan | |||
| CHEMBL3955804 | 150767 | None | 0 | Human | Binding | pIC50 | = | 5.8 | 5.8 | - | 0 | ChEMBL | 286 | 1 | 0 | 4 | 1.5 | Cc1ccccc1C1=CS(=O)(=O)CCCS1(=O)=O | nan | |||
| 57401227 | 68851 | None | 0 | Human | Binding | pIC50 | = | 4.8 | 4.8 | - | 0 | ChEMBL | 506 | 8 | 2 | 8 | 5.6 | COc1ccc(Nc2nc(Nc3ccc(OC)c(F)c3)cc(N3CCC(N4CCCCC4)CC3)n2)cc1 | 10.1016/j.bmcl.2011.09.033 | |||
| CHEMBL1922024 | 68851 | None | 0 | Human | Binding | pIC50 | = | 4.8 | 4.8 | - | 0 | ChEMBL | 506 | 8 | 2 | 8 | 5.6 | COc1ccc(Nc2nc(Nc3ccc(OC)c(F)c3)cc(N3CCC(N4CCCCC4)CC3)n2)cc1 | 10.1016/j.bmcl.2011.09.033 | |||
| 6124 | 1439 | None | 0 | Human | Binding | pIC50 | = | 6.7 | 6.7 | - | 0 | ChEMBL | 286 | 1 | 0 | 4 | 1.5 | Cc1ccc(cc1)C1=CS(=O)(=O)CCCS1(=O)=O | nan | |||
| 9947811 | 1439 | None | 0 | Human | Binding | pIC50 | = | 6.7 | 6.7 | - | 0 | ChEMBL | 286 | 1 | 0 | 4 | 1.5 | Cc1ccc(cc1)C1=CS(=O)(=O)CCCS1(=O)=O | nan | |||
| CHEMBL3906195 | 1439 | None | 0 | Human | Binding | pIC50 | = | 6.7 | 6.7 | - | 0 | ChEMBL | 286 | 1 | 0 | 4 | 1.5 | Cc1ccc(cc1)C1=CS(=O)(=O)CCCS1(=O)=O | nan | |||
| 91273519 | 143576 | None | 0 | Human | Binding | pIC50 | = | 5.7 | 5.7 | - | 0 | ChEMBL | 306 | 1 | 0 | 4 | 1.9 | O=S1(=O)C=C(c2ccc(Cl)cc2)S(=O)(=O)CCC1 | nan | |||
| CHEMBL3898656 | 143576 | None | 0 | Human | Binding | pIC50 | = | 5.7 | 5.7 | - | 0 | ChEMBL | 306 | 1 | 0 | 4 | 1.9 | O=S1(=O)C=C(c2ccc(Cl)cc2)S(=O)(=O)CCC1 | nan | |||
| CHEMBL475845 | 216528 | None | 0 | Rat | Binding | pIC50 | = | 7.7 | 7.7 | - | 0 | ChEMBL | None | None | None | CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@H](CS(=O)(=O)O)C(C)=O)NC(=O)[C@H]([C@@H](C)CC)NC1=O | 10.1016/j.bmcl.2008.10.104 | |||||
| 9862765 | 147457 | None | 0 | Human | Binding | pIC50 | = | 5.7 | 5.7 | - | 0 | ChEMBL | 340 | 1 | 0 | 4 | 2.2 | O=S1(=O)C=C(c2ccc(C(F)(F)F)cc2)S(=O)(=O)CCC1 | nan | |||
| CHEMBL3929524 | 147457 | None | 0 | Human | Binding | pIC50 | = | 5.7 | 5.7 | - | 0 | ChEMBL | 340 | 1 | 0 | 4 | 2.2 | O=S1(=O)C=C(c2ccc(C(F)(F)F)cc2)S(=O)(=O)CCC1 | nan | |||
| 9884806 | 149002 | None | 0 | Human | Binding | pIC50 | = | 6.6 | 6.6 | - | 0 | ChEMBL | 350 | 1 | 0 | 4 | 2.0 | O=S1(=O)C=C(c2ccc(Br)cc2)S(=O)(=O)CCC1 | nan | |||
| CHEMBL3941767 | 149002 | None | 0 | Human | Binding | pIC50 | = | 6.6 | 6.6 | - | 0 | ChEMBL | 350 | 1 | 0 | 4 | 2.0 | O=S1(=O)C=C(c2ccc(Br)cc2)S(=O)(=O)CCC1 | nan | |||
| 9795483 | 145384 | None | 0 | Human | Binding | pIC50 | = | 5.6 | 5.6 | - | 0 | ChEMBL | 272 | 1 | 0 | 4 | 1.2 | O=S1(=O)C=C(c2ccccc2)S(=O)(=O)CCC1 | nan | |||
| CHEMBL3913089 | 145384 | None | 0 | Human | Binding | pIC50 | = | 5.6 | 5.6 | - | 0 | ChEMBL | 272 | 1 | 0 | 4 | 1.2 | O=S1(=O)C=C(c2ccccc2)S(=O)(=O)CCC1 | nan | |||
| 13651848 | 147121 | None | 2 | Human | Binding | pIC50 | = | 5.6 | 5.6 | - | 0 | ChEMBL | 258 | 1 | 0 | 4 | 0.8 | O=S1(=O)C=C(c2ccccc2)S(=O)(=O)CC1 | nan | |||
| CHEMBL3926775 | 147121 | None | 2 | Human | Binding | pIC50 | = | 5.6 | 5.6 | - | 0 | ChEMBL | 258 | 1 | 0 | 4 | 0.8 | O=S1(=O)C=C(c2ccccc2)S(=O)(=O)CC1 | nan | |||
| 9798779 | 152757 | None | 0 | Human | Binding | pIC50 | = | 5.6 | 5.6 | - | 0 | ChEMBL | 356 | 2 | 0 | 5 | 2.1 | O=S1(=O)C=C(c2cccc(OC(F)(F)F)c2)S(=O)(=O)CCC1 | nan | |||
| CHEMBL3972601 | 152757 | None | 0 | Human | Binding | pIC50 | = | 5.6 | 5.6 | - | 0 | ChEMBL | 356 | 2 | 0 | 5 | 2.1 | O=S1(=O)C=C(c2cccc(OC(F)(F)F)c2)S(=O)(=O)CCC1 | nan | |||
| 57395993 | 68824 | None | 0 | Human | Binding | pIC50 | = | 4.6 | 4.6 | - | 0 | ChEMBL | 455 | 9 | 3 | 7 | 6.3 | COc1ccc(Nc2cc(Nc3ccc(OC(F)F)cc3)nc(NC3CCCCC3)n2)cc1 | 10.1016/j.bmcl.2011.09.033 | |||
| CHEMBL1921995 | 68824 | None | 0 | Human | Binding | pIC50 | = | 4.6 | 4.6 | - | 0 | ChEMBL | 455 | 9 | 3 | 7 | 6.3 | COc1ccc(Nc2cc(Nc3ccc(OC(F)F)cc3)nc(NC3CCCCC3)n2)cc1 | 10.1016/j.bmcl.2011.09.033 | |||
| 57401228 | 68852 | None | 0 | Human | Binding | pIC50 | = | 5.6 | 5.6 | - | 0 | ChEMBL | 538 | 7 | 2 | 9 | 5.6 | COc1ccc(Nc2nc(Nc3ccc(OC)c(F)c3)cc(N3CCCN(C(=O)OC(C)(C)C)CC3)n2)cc1 | 10.1016/j.bmcl.2011.09.033 | |||
| CHEMBL1922025 | 68852 | None | 0 | Human | Binding | pIC50 | = | 5.6 | 5.6 | - | 0 | ChEMBL | 538 | 7 | 2 | 9 | 5.6 | COc1ccc(Nc2nc(Nc3ccc(OC)c(F)c3)cc(N3CCCN(C(=O)OC(C)(C)C)CC3)n2)cc1 | 10.1016/j.bmcl.2011.09.033 | |||
| CHEMBL514318 | 218085 | None | 0 | Rat | Binding | pIC50 | = | 7.5 | 7.5 | - | 0 | ChEMBL | None | None | None | CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H]([C@@H](C)CC)NC1=O | 10.1016/j.bmcl.2008.10.104 | |||||
| 6604909 | 64303 | None | 12 | Rat | Binding | pIC50 | = | 8.5 | 8.5 | - | 0 | ChEMBL | 393 | 9 | 1 | 3 | 5.0 | CN(CC[C@@H](Oc1ccc(-c2ccccc2)cc1)c1ccc(F)cc1)CC(=O)O | 10.1016/j.bmcl.2008.10.104 | |||
| 86306255 | 64303 | None | 12 | Rat | Binding | pIC50 | = | 8.5 | 8.5 | - | 0 | ChEMBL | 393 | 9 | 1 | 3 | 5.0 | CN(CC[C@@H](Oc1ccc(-c2ccccc2)cc1)c1ccc(F)cc1)CC(=O)O | 10.1016/j.bmcl.2008.10.104 | |||
| CHEMBL180966 | 64303 | None | 12 | Rat | Binding | pIC50 | = | 8.5 | 8.5 | - | 0 | ChEMBL | 393 | 9 | 1 | 3 | 5.0 | CN(CC[C@@H](Oc1ccc(-c2ccccc2)cc1)c1ccc(F)cc1)CC(=O)O | 10.1016/j.bmcl.2008.10.104 | |||
| CHEMBL515145 | 218087 | None | 0 | Rat | Binding | pIC50 | = | 8.5 | 8.5 | - | 0 | ChEMBL | None | None | None | CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H]([C@H](C)[C@@H](C)O)NC(=O)[C@H]([C@@H](C)CC)NC1=O | 10.1016/j.bmcl.2008.10.104 | |||||
| 57397798 | 68830 | None | 0 | Human | Binding | pIC50 | = | 5.5 | 5.5 | - | 0 | ChEMBL | 527 | 6 | 1 | 8 | 5.4 | COc1ccc(Nc2cc(N3CCCCC3)nc(N3CCCN(c4ncccc4C(F)(F)F)CC3)n2)cc1 | 10.1016/j.bmcl.2011.09.033 | |||
| CHEMBL1922000 | 68830 | None | 0 | Human | Binding | pIC50 | = | 5.5 | 5.5 | - | 0 | ChEMBL | 527 | 6 | 1 | 8 | 5.4 | COc1ccc(Nc2cc(N3CCCCC3)nc(N3CCCN(c4ncccc4C(F)(F)F)CC3)n2)cc1 | 10.1016/j.bmcl.2011.09.033 | |||
| 57394304 | 68766 | None | 0 | Human | Binding | pIC50 | = | 4.5 | 4.5 | - | 0 | ChEMBL | 429 | 6 | 2 | 6 | 5.9 | FC(F)(F)Oc1cccc(Nc2cc(Nc3ccccc3)nc(N3CCCCC3)n2)c1 | 10.1016/j.bmcl.2011.09.033 | |||
| CHEMBL1921903 | 68766 | None | 0 | Human | Binding | pIC50 | = | 4.5 | 4.5 | - | 0 | ChEMBL | 429 | 6 | 2 | 6 | 5.9 | FC(F)(F)Oc1cccc(Nc2cc(Nc3ccccc3)nc(N3CCCCC3)n2)c1 | 10.1016/j.bmcl.2011.09.033 | |||
| 91167010 | 150763 | None | 0 | Human | Binding | pIC50 | = | 6.4 | 6.4 | - | 0 | ChEMBL | 322 | 1 | 0 | 4 | 2.4 | O=S1(=O)C=C(c2cccc3ccccc23)S(=O)(=O)CCC1 | nan | |||
| CHEMBL3955764 | 150763 | None | 0 | Human | Binding | pIC50 | = | 6.4 | 6.4 | - | 0 | ChEMBL | 322 | 1 | 0 | 4 | 2.4 | O=S1(=O)C=C(c2cccc3ccccc23)S(=O)(=O)CCC1 | nan | |||
| 57401226 | 68848 | None | 0 | Human | Binding | pIC50 | = | 5.4 | 5.4 | - | 0 | ChEMBL | 451 | 9 | 3 | 7 | 6.1 | COc1ccc(Nc2nc(NCC3CCCCC3)cc(Nc3ccc(OC)c(F)c3)n2)cc1 | 10.1016/j.bmcl.2011.09.033 | |||
| CHEMBL1922021 | 68848 | None | 0 | Human | Binding | pIC50 | = | 5.4 | 5.4 | - | 0 | ChEMBL | 451 | 9 | 3 | 7 | 6.1 | COc1ccc(Nc2nc(NCC3CCCCC3)cc(Nc3ccc(OC)c(F)c3)n2)cc1 | 10.1016/j.bmcl.2011.09.033 | |||
| 57395996 | 68849 | None | 0 | Human | Binding | pIC50 | = | 5.4 | 5.4 | - | 0 | ChEMBL | 502 | 8 | 2 | 10 | 4.2 | COc1ccc(Nc2nc(Nc3ccc(OC)c(F)c3)cc(N3CCN(c4ncccn4)CC3)n2)cc1 | 10.1016/j.bmcl.2011.09.033 | |||
| CHEMBL1922022 | 68849 | None | 0 | Human | Binding | pIC50 | = | 5.4 | 5.4 | - | 0 | ChEMBL | 502 | 8 | 2 | 10 | 4.2 | COc1ccc(Nc2nc(Nc3ccc(OC)c(F)c3)cc(N3CCN(c4ncccn4)CC3)n2)cc1 | 10.1016/j.bmcl.2011.09.033 | |||
| 57395994 | 68831 | None | 0 | Human | Binding | pIC50 | = | 5.4 | 5.4 | - | 0 | ChEMBL | 525 | 5 | 1 | 7 | 6.0 | Cc1ccc(C)c(Nc2cc(N3CCCCC3)nc(N3CCCN(c4ncccc4C(F)(F)F)CC3)n2)c1 | 10.1016/j.bmcl.2011.09.033 | |||
| CHEMBL1922001 | 68831 | None | 0 | Human | Binding | pIC50 | = | 5.4 | 5.4 | - | 0 | ChEMBL | 525 | 5 | 1 | 7 | 6.0 | Cc1ccc(C)c(Nc2cc(N3CCCCC3)nc(N3CCCN(c4ncccc4C(F)(F)F)CC3)n2)c1 | 10.1016/j.bmcl.2011.09.033 | |||
| 9860799 | 149353 | None | 0 | Human | Binding | pIC50 | = | 6.4 | 6.4 | - | 0 | ChEMBL | 290 | 1 | 0 | 4 | 1.4 | O=S1(=O)C=C(c2ccc(F)cc2)S(=O)(=O)CCC1 | nan | |||
| CHEMBL3944461 | 149353 | None | 0 | Human | Binding | pIC50 | = | 6.4 | 6.4 | - | 0 | ChEMBL | 290 | 1 | 0 | 4 | 1.4 | O=S1(=O)C=C(c2ccc(F)cc2)S(=O)(=O)CCC1 | nan | |||
| 9799171 | 151100 | None | 0 | Human | Binding | pIC50 | = | 6.4 | 6.4 | - | 0 | ChEMBL | 364 | 3 | 0 | 5 | 3.0 | O=S1(=O)C=C(c2ccc(Oc3ccccc3)cc2)S(=O)(=O)CCC1 | nan | |||
| CHEMBL3958445 | 151100 | None | 0 | Human | Binding | pIC50 | = | 6.4 | 6.4 | - | 0 | ChEMBL | 364 | 3 | 0 | 5 | 3.0 | O=S1(=O)C=C(c2ccc(Oc3ccccc3)cc2)S(=O)(=O)CCC1 | nan | |||
| 91591245 | 144153 | None | 0 | Human | Binding | pIC50 | = | 6.4 | 6.4 | - | 0 | ChEMBL | 290 | 1 | 0 | 4 | 1.4 | O=S1(=O)C=C(c2ccccc2F)S(=O)(=O)CCC1 | nan | |||
| CHEMBL3903219 | 144153 | None | 0 | Human | Binding | pIC50 | = | 6.4 | 6.4 | - | 0 | ChEMBL | 290 | 1 | 0 | 4 | 1.4 | O=S1(=O)C=C(c2ccccc2F)S(=O)(=O)CCC1 | nan | |||
| 9861140 | 149289 | None | 0 | Human | Binding | pIC50 | = | 6.4 | 6.4 | - | 0 | ChEMBL | 300 | 2 | 0 | 4 | 1.8 | CCc1ccc(C2=CS(=O)(=O)CCCS2(=O)=O)cc1 | nan | |||
| CHEMBL3943955 | 149289 | None | 0 | Human | Binding | pIC50 | = | 6.4 | 6.4 | - | 0 | ChEMBL | 300 | 2 | 0 | 4 | 1.8 | CCc1ccc(C2=CS(=O)(=O)CCCS2(=O)=O)cc1 | nan | |||
| 101061653 | 148993 | None | 0 | Human | Binding | pIC50 | = | 6.4 | 6.4 | - | 0 | ChEMBL | 392 | 3 | 0 | 6 | 2.4 | O=C(Oc1ccccc1)c1cccc(C2=CS(=O)(=O)CCCS2(=O)=O)c1 | nan | |||
| CHEMBL3941717 | 148993 | None | 0 | Human | Binding | pIC50 | = | 6.4 | 6.4 | - | 0 | ChEMBL | 392 | 3 | 0 | 6 | 2.4 | O=C(Oc1ccccc1)c1cccc(C2=CS(=O)(=O)CCCS2(=O)=O)c1 | nan | |||
| 57394236 | 68822 | None | 0 | Human | Binding | pIC50 | = | 5.3 | 5.3 | - | 0 | ChEMBL | 391 | 7 | 2 | 7 | 4.6 | COc1ccc(Nc2cc(Nc3cccc(OC)c3)nc(N3CCCC3)n2)cc1 | 10.1016/j.bmcl.2011.09.033 | |||
| CHEMBL1921993 | 68822 | None | 0 | Human | Binding | pIC50 | = | 5.3 | 5.3 | - | 0 | ChEMBL | 391 | 7 | 2 | 7 | 4.6 | COc1ccc(Nc2cc(Nc3cccc(OC)c3)nc(N3CCCC3)n2)cc1 | 10.1016/j.bmcl.2011.09.033 | |||
| 90940684 | 146106 | None | 0 | Human | Binding | pIC50 | = | 6.3 | 6.3 | - | 0 | ChEMBL | 356 | 2 | 0 | 5 | 2.1 | O=S1(=O)C=C(c2ccc(OC(F)(F)F)cc2)S(=O)(=O)CCC1 | nan | |||
| CHEMBL3918646 | 146106 | None | 0 | Human | Binding | pIC50 | = | 6.3 | 6.3 | - | 0 | ChEMBL | 356 | 2 | 0 | 5 | 2.1 | O=S1(=O)C=C(c2ccc(OC(F)(F)F)cc2)S(=O)(=O)CCC1 | nan | |||
| 57401221 | 68825 | None | 0 | Human | Binding | pIC50 | = | 5.3 | 5.3 | - | 0 | ChEMBL | 455 | 9 | 3 | 7 | 6.3 | COc1ccc(Nc2cc(Nc3cccc(OC(F)F)c3)nc(NC3CCCCC3)n2)cc1 | 10.1016/j.bmcl.2011.09.033 | |||
| CHEMBL1921996 | 68825 | None | 0 | Human | Binding | pIC50 | = | 5.3 | 5.3 | - | 0 | ChEMBL | 455 | 9 | 3 | 7 | 6.3 | COc1ccc(Nc2cc(Nc3cccc(OC(F)F)c3)nc(NC3CCCCC3)n2)cc1 | 10.1016/j.bmcl.2011.09.033 | |||
| 57390716 | 68845 | None | 0 | Human | Binding | pIC50 | = | 5.3 | 5.3 | - | 0 | ChEMBL | 437 | 7 | 2 | 7 | 5.5 | COc1ccc(Nc2nc(Nc3ccc(OC)c(F)c3)cc(N3CCCCCC3)n2)cc1 | 10.1016/j.bmcl.2011.09.033 | |||
| CHEMBL1922016 | 68845 | None | 0 | Human | Binding | pIC50 | = | 5.3 | 5.3 | - | 0 | ChEMBL | 437 | 7 | 2 | 7 | 5.5 | COc1ccc(Nc2nc(Nc3ccc(OC)c(F)c3)cc(N3CCCCCC3)n2)cc1 | 10.1016/j.bmcl.2011.09.033 | |||
| 57394237 | 68827 | None | 0 | Human | Binding | pIC50 | = | 5.3 | 5.3 | - | 0 | ChEMBL | 419 | 8 | 3 | 7 | 5.7 | COc1ccc(Nc2cc(Nc3cccc(OC)c3)nc(NC3CCCCC3)n2)cc1 | 10.1016/j.bmcl.2011.09.033 | |||
| CHEMBL1921998 | 68827 | None | 0 | Human | Binding | pIC50 | = | 5.3 | 5.3 | - | 0 | ChEMBL | 419 | 8 | 3 | 7 | 5.7 | COc1ccc(Nc2cc(Nc3cccc(OC)c3)nc(NC3CCCCC3)n2)cc1 | 10.1016/j.bmcl.2011.09.033 | |||
| 91414022 | 146507 | None | 0 | Human | Binding | pIC50 | = | 6.2 | 6.2 | - | 0 | ChEMBL | 350 | 1 | 0 | 4 | 2.0 | O=S1(=O)C=C(c2ccccc2Br)S(=O)(=O)CCC1 | nan | |||
| CHEMBL3921852 | 146507 | None | 0 | Human | Binding | pIC50 | = | 6.2 | 6.2 | - | 0 | ChEMBL | 350 | 1 | 0 | 4 | 2.0 | O=S1(=O)C=C(c2ccccc2Br)S(=O)(=O)CCC1 | nan | |||
| 91016278 | 146160 | None | 0 | Human | Binding | pIC50 | = | 6.2 | 6.2 | - | 0 | ChEMBL | 340 | 1 | 0 | 4 | 2.2 | O=S1(=O)C=C(c2ccccc2C(F)(F)F)S(=O)(=O)CCC1 | nan | |||
| CHEMBL3919125 | 146160 | None | 0 | Human | Binding | pIC50 | = | 6.2 | 6.2 | - | 0 | ChEMBL | 340 | 1 | 0 | 4 | 2.2 | O=S1(=O)C=C(c2ccccc2C(F)(F)F)S(=O)(=O)CCC1 | nan | |||
| 9861729 | 144471 | None | 0 | Human | Binding | pIC50 | = | 6.2 | 6.2 | - | 0 | ChEMBL | 316 | 3 | 0 | 5 | 1.6 | CCOc1ccc(C2=CS(=O)(=O)CCCS2(=O)=O)cc1 | nan | |||
| CHEMBL3905888 | 144471 | None | 0 | Human | Binding | pIC50 | = | 6.2 | 6.2 | - | 0 | ChEMBL | 316 | 3 | 0 | 5 | 1.6 | CCOc1ccc(C2=CS(=O)(=O)CCCS2(=O)=O)cc1 | nan | |||
| 57392517 | 68826 | None | 0 | Human | Binding | pIC50 | = | 5.2 | 5.2 | - | 0 | ChEMBL | 473 | 8 | 3 | 7 | 6.6 | COc1ccc(Nc2cc(Nc3ccc(OC(F)(F)F)cc3)nc(NC3CCCCC3)n2)cc1 | 10.1016/j.bmcl.2011.09.033 | |||
| CHEMBL1921997 | 68826 | None | 0 | Human | Binding | pIC50 | = | 5.2 | 5.2 | - | 0 | ChEMBL | 473 | 8 | 3 | 7 | 6.6 | COc1ccc(Nc2cc(Nc3ccc(OC(F)(F)F)cc3)nc(NC3CCCCC3)n2)cc1 | 10.1016/j.bmcl.2011.09.033 | |||
| 9884699 | 142703 | None | 0 | Human | Binding | pIC50 | = | 6.2 | 6.2 | - | 0 | ChEMBL | 348 | 2 | 0 | 4 | 2.9 | O=S1(=O)C=C(c2ccc(-c3ccccc3)cc2)S(=O)(=O)CCC1 | nan | |||
| CHEMBL3891488 | 142703 | None | 0 | Human | Binding | pIC50 | = | 6.2 | 6.2 | - | 0 | ChEMBL | 348 | 2 | 0 | 4 | 2.9 | O=S1(=O)C=C(c2ccc(-c3ccccc3)cc2)S(=O)(=O)CCC1 | nan | |||
| 91055417 | 147901 | None | 0 | Human | Binding | pIC50 | = | 6.2 | 6.2 | - | 0 | ChEMBL | 340 | 1 | 0 | 4 | 2.2 | O=S1(=O)C=C(c2cccc(C(F)(F)F)c2)S(=O)(=O)CCC1 | nan | |||
| CHEMBL3932833 | 147901 | None | 0 | Human | Binding | pIC50 | = | 6.2 | 6.2 | - | 0 | ChEMBL | 340 | 1 | 0 | 4 | 2.2 | O=S1(=O)C=C(c2cccc(C(F)(F)F)c2)S(=O)(=O)CCC1 | nan | |||
| 57399458 | 68832 | None | 0 | Human | Binding | pIC50 | = | 5.2 | 5.2 | - | 0 | ChEMBL | 545 | 6 | 1 | 8 | 5.5 | COc1ccc(Nc2cc(N3CCCCC3)nc(N3CCCN(c4ncccc4C(F)(F)F)CC3)n2)cc1F | 10.1016/j.bmcl.2011.09.033 | |||
| CHEMBL1922002 | 68832 | None | 0 | Human | Binding | pIC50 | = | 5.2 | 5.2 | - | 0 | ChEMBL | 545 | 6 | 1 | 8 | 5.5 | COc1ccc(Nc2cc(N3CCCCC3)nc(N3CCCN(c4ncccc4C(F)(F)F)CC3)n2)cc1F | 10.1016/j.bmcl.2011.09.033 | |||
| 9948494 | 144529 | None | 0 | Human | Binding | pIC50 | = | 6.2 | 6.2 | - | 0 | ChEMBL | 306 | 1 | 0 | 4 | 1.9 | O=S1(=O)C=C(c2ccccc2Cl)S(=O)(=O)CCC1 | nan | |||
| CHEMBL3906449 | 144529 | None | 0 | Human | Binding | pIC50 | = | 6.2 | 6.2 | - | 0 | ChEMBL | 306 | 1 | 0 | 4 | 1.9 | O=S1(=O)C=C(c2ccccc2Cl)S(=O)(=O)CCC1 | nan | |||
| 57395992 | 68820 | None | 0 | Human | Binding | pIC50 | = | 5.2 | 5.2 | - | 0 | ChEMBL | 393 | 6 | 2 | 6 | 5.1 | COc1ccc(Nc2cc(Nc3ccccc3)nc(N3CCCCC3)n2)cc1F | 10.1016/j.bmcl.2011.09.033 | |||
| CHEMBL1921991 | 68820 | None | 0 | Human | Binding | pIC50 | = | 5.2 | 5.2 | - | 0 | ChEMBL | 393 | 6 | 2 | 6 | 5.1 | COc1ccc(Nc2cc(Nc3ccccc3)nc(N3CCCCC3)n2)cc1F | 10.1016/j.bmcl.2011.09.033 | |||
| 57401225 | 68847 | None | 0 | Human | Binding | pIC50 | = | 5.2 | 5.2 | - | 0 | ChEMBL | 437 | 7 | 2 | 7 | 5.4 | COc1ccc(Nc2nc(Nc3ccc(OC)c(F)c3)cc(N3CCCC(C)C3)n2)cc1 | 10.1016/j.bmcl.2011.09.033 | |||
| CHEMBL1922019 | 68847 | None | 0 | Human | Binding | pIC50 | = | 5.2 | 5.2 | - | 0 | ChEMBL | 437 | 7 | 2 | 7 | 5.4 | COc1ccc(Nc2nc(Nc3ccc(OC)c(F)c3)cc(N3CCCC(C)C3)n2)cc1 | 10.1016/j.bmcl.2011.09.033 | |||
| 57399457 | 68828 | None | 0 | Human | Binding | pIC50 | = | 5.2 | 5.2 | - | 0 | ChEMBL | 473 | 8 | 3 | 7 | 6.6 | COc1ccc(Nc2cc(Nc3cccc(OC(F)(F)F)c3)nc(NC3CCCCC3)n2)cc1 | 10.1016/j.bmcl.2011.09.033 | |||
| CHEMBL1921999 | 68828 | None | 0 | Human | Binding | pIC50 | = | 5.2 | 5.2 | - | 0 | ChEMBL | 473 | 8 | 3 | 7 | 6.6 | COc1ccc(Nc2cc(Nc3cccc(OC(F)(F)F)c3)nc(NC3CCCCC3)n2)cc1 | 10.1016/j.bmcl.2011.09.033 | |||
| 57390718 | 68850 | None | 0 | Human | Binding | pIC50 | = | 5.2 | 5.2 | - | 0 | ChEMBL | 500 | 8 | 2 | 8 | 5.4 | COc1ccc(Nc2nc(Nc3ccc(OC)c(F)c3)cc(N3CCN(c4ccccc4)CC3)n2)cc1 | 10.1016/j.bmcl.2011.09.033 | |||
| CHEMBL1922023 | 68850 | None | 0 | Human | Binding | pIC50 | = | 5.2 | 5.2 | - | 0 | ChEMBL | 500 | 8 | 2 | 8 | 5.4 | COc1ccc(Nc2nc(Nc3ccc(OC)c(F)c3)cc(N3CCN(c4ccccc4)CC3)n2)cc1 | 10.1016/j.bmcl.2011.09.033 | |||
| 57401220 | 68818 | None | 0 | Human | Binding | pIC50 | = | 5.2 | 5.2 | - | 0 | ChEMBL | 411 | 7 | 2 | 6 | 5.6 | FC(F)Oc1cccc(Nc2cc(Nc3ccccc3)nc(N3CCCCC3)n2)c1 | 10.1016/j.bmcl.2011.09.033 | |||
| CHEMBL1921989 | 68818 | None | 0 | Human | Binding | pIC50 | = | 5.2 | 5.2 | - | 0 | ChEMBL | 411 | 7 | 2 | 6 | 5.6 | FC(F)Oc1cccc(Nc2cc(Nc3ccccc3)nc(N3CCCCC3)n2)c1 | 10.1016/j.bmcl.2011.09.033 | |||
| 9843783 | 146386 | None | 0 | Human | Binding | pIC50 | = | 6.2 | 6.2 | - | 0 | ChEMBL | 398 | 1 | 0 | 4 | 1.8 | O=S1(=O)C=C(c2ccc(I)cc2)S(=O)(=O)CCC1 | nan | |||
| CHEMBL3920910 | 146386 | None | 0 | Human | Binding | pIC50 | = | 6.2 | 6.2 | - | 0 | ChEMBL | 398 | 1 | 0 | 4 | 1.8 | O=S1(=O)C=C(c2ccc(I)cc2)S(=O)(=O)CCC1 | nan | |||
| 134151208 | 152052 | None | 0 | Human | Binding | pIC50 | = | 5.1 | 5.1 | - | 0 | ChEMBL | 301 | 3 | 1 | 5 | 0.2 | NC(Cc1ccccc1)C1=CS(=O)(=O)CCS1(=O)=O | nan | |||
| CHEMBL3966583 | 152052 | None | 0 | Human | Binding | pIC50 | = | 5.1 | 5.1 | - | 0 | ChEMBL | 301 | 3 | 1 | 5 | 0.2 | NC(Cc1ccccc1)C1=CS(=O)(=O)CCS1(=O)=O | nan | |||
| 90761518 | 148939 | None | 0 | Human | Binding | pIC50 | = | 6.1 | 6.1 | - | 0 | ChEMBL | 398 | 1 | 0 | 4 | 1.8 | O=S1(=O)C=C(c2cccc(I)c2)S(=O)(=O)CCC1 | nan | |||
| CHEMBL3941261 | 148939 | None | 0 | Human | Binding | pIC50 | = | 6.1 | 6.1 | - | 0 | ChEMBL | 398 | 1 | 0 | 4 | 1.8 | O=S1(=O)C=C(c2cccc(I)c2)S(=O)(=O)CCC1 | nan | |||
| 57396058 | 68765 | None | 0 | Human | Binding | pIC50 | = | 5.1 | 5.1 | - | 0 | ChEMBL | 375 | 6 | 2 | 6 | 5.0 | COc1ccc(Nc2cc(Nc3ccccc3)nc(N3CCCCC3)n2)cc1 | 10.1016/j.bmcl.2011.09.033 | |||
| CHEMBL1921902 | 68765 | None | 0 | Human | Binding | pIC50 | = | 5.1 | 5.1 | - | 0 | ChEMBL | 375 | 6 | 2 | 6 | 5.0 | COc1ccc(Nc2cc(Nc3ccccc3)nc(N3CCCCC3)n2)cc1 | 10.1016/j.bmcl.2011.09.033 | |||
| 9798525 | 148110 | None | 0 | Human | Binding | pIC50 | = | 6.1 | 6.1 | - | 0 | ChEMBL | 350 | 1 | 0 | 4 | 2.0 | O=S1(=O)C=C(c2cccc(Br)c2)S(=O)(=O)CCC1 | nan | |||
| CHEMBL3934499 | 148110 | None | 0 | Human | Binding | pIC50 | = | 6.1 | 6.1 | - | 0 | ChEMBL | 350 | 1 | 0 | 4 | 2.0 | O=S1(=O)C=C(c2cccc(Br)c2)S(=O)(=O)CCC1 | nan | |||
| 9904495 | 153616 | None | 0 | Human | Binding | pIC50 | = | 6.0 | 6.0 | - | 0 | ChEMBL | 302 | 2 | 0 | 5 | 1.2 | COc1cccc(C2=CS(=O)(=O)CCCS2(=O)=O)c1 | nan | |||
| CHEMBL3979946 | 153616 | None | 0 | Human | Binding | pIC50 | = | 6.0 | 6.0 | - | 0 | ChEMBL | 302 | 2 | 0 | 5 | 1.2 | COc1cccc(C2=CS(=O)(=O)CCCS2(=O)=O)c1 | nan | |||
| CHEMBL451169 | 216428 | None | 0 | Rat | Binding | pIC50 | = | 7.0 | 7.0 | - | 0 | ChEMBL | None | None | None | CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2cn(OC)c3ccccc23)NC(=O)[C@H](CCCCC(C)=O)NC(=O)[C@H]2CCCCN2C1=O | 10.1016/j.bmcl.2008.10.104 | |||||
| CHEMBL503473 | 216655 | None | 15 | Human | Binding | pKd | = | 10 | 10.0 | 60 | 3 | ChEMBL | None | None | None | CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CN)[C@@H](C)O)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(N)=O | 10.1021/jm801088x | |||||
| CHEMBL526003 | 218159 | None | 24 | Human | Binding | pKd | = | 9.5 | 9.5 | 10 | 3 | ChEMBL | None | None | None | CSCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CN)[C@@H](C)O)C(N)=O | 10.1021/jm801088x | |||||
| 155817464 | 1499 | None | 0 | Human | Binding | pKd | = | 9.4 | 9.4 | 5 | 4 | ChEMBL | None | None | None | None | 10.1021/jm801088x | |||||
| 3866 | 1499 | None | 0 | Human | Binding | pKd | = | 9.4 | 9.4 | 5 | 4 | ChEMBL | None | None | None | None | 10.1021/jm801088x | |||||
| 44587986 | 1499 | None | 0 | Human | Binding | pKd | = | 9.4 | 9.4 | 5 | 4 | ChEMBL | None | None | None | None | 10.1021/jm801088x | |||||
| 91934870 | 1499 | None | 0 | Human | Binding | pKd | = | 9.4 | 9.4 | 5 | 4 | ChEMBL | None | None | None | None | 10.1021/jm801088x | |||||
| CHEMBL499179 | 1499 | None | 0 | Human | Binding | pKd | = | 9.4 | 9.4 | 5 | 4 | ChEMBL | None | None | None | None | 10.1021/jm801088x | |||||
| 71717271 | 86124 | None | 0 | Human | Binding | pKd | = | 4.9 | 4.9 | 1 | 3 | ChEMBL | 678 | 13 | 4 | 7 | 6.5 | Cc1cc(=O)oc2cc(NC(=O)[C@@H](CCCCN)NC(=O)[C@H](CC3CCCCC3)NC(=O)OCC3c4ccccc4-c4ccccc43)ccc12 | 10.1021/jm801088x | |||
| CHEMBL2309599 | 86124 | None | 0 | Human | Binding | pKd | = | 4.9 | 4.9 | 1 | 3 | ChEMBL | 678 | 13 | 4 | 7 | 6.5 | Cc1cc(=O)oc2cc(NC(=O)[C@@H](CCCCN)NC(=O)[C@H](CC3CCCCC3)NC(=O)OCC3c4ccccc4-c4ccccc43)ccc12 | 10.1021/jm801088x | |||
| 16132180 | 1724 | None | 20 | Human | Binding | pKd | = | 8.5 | 8.5 | -1 | 8 | ChEMBL | None | None | None | None | 10.1021/jm801088x | |||||
| 16133822 | 1724 | None | 20 | Human | Binding | pKd | = | 8.5 | 8.5 | -1 | 8 | ChEMBL | None | None | None | None | 10.1021/jm801088x | |||||
| 6087 | 1724 | None | 20 | Human | Binding | pKd | = | 8.5 | 8.5 | -1 | 8 | ChEMBL | None | None | None | None | 10.1021/jm801088x | |||||
| CHEMBL499980 | 1724 | None | 20 | Human | Binding | pKd | = | 8.5 | 8.5 | -1 | 8 | ChEMBL | None | None | None | None | 10.1021/jm801088x | |||||
| 24748735 | 1755 | None | 2 | Human | Binding | pKd | = | 4.5 | 4.5 | -3 | 2 | ChEMBL | 988 | 12 | 7 | 15 | 4.2 | NCCCC[C@@H](C(=O)OC)NC(=O)[C@]1(C)NC(=O)c2nc(oc2C)[C@@](C)(NC(=O)c2nc([C@](NC(=O)c3nc1oc3C)(C)C(=O)NCC1CCCCC1)oc2C)C(=O)NC1c2ccccc2c2c1cccc2 | 10.1021/jm801088x | |||
| 6119 | 1755 | None | 2 | Human | Binding | pKd | = | 4.5 | 4.5 | -3 | 2 | ChEMBL | 988 | 12 | 7 | 15 | 4.2 | NCCCC[C@@H](C(=O)OC)NC(=O)[C@]1(C)NC(=O)c2nc(oc2C)[C@@](C)(NC(=O)c2nc([C@](NC(=O)c3nc1oc3C)(C)C(=O)NCC1CCCCC1)oc2C)C(=O)NC1c2ccccc2c2c1cccc2 | 10.1021/jm801088x | |||
| CHEMBL1187471 | 1755 | None | 2 | Human | Binding | pKd | = | 4.5 | 4.5 | -3 | 2 | ChEMBL | 988 | 12 | 7 | 15 | 4.2 | NCCCC[C@@H](C(=O)OC)NC(=O)[C@]1(C)NC(=O)c2nc(oc2C)[C@@](C)(NC(=O)c2nc([C@](NC(=O)c3nc1oc3C)(C)C(=O)NCC1CCCCC1)oc2C)C(=O)NC1c2ccccc2c2c1cccc2 | 10.1021/jm801088x | |||
| CHEMBL506210 | 216693 | None | 0 | Human | Binding | pKd | = | 6.1 | 6.1 | -478 | 2 | ChEMBL | None | None | None | None | 10.1021/jm801088x | |||||
| CHEMBL503473 | 216655 | None | 15 | Human | Binding | pKi | = | 11 | 11.0 | 60 | 3 | ChEMBL | None | None | None | CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CN)[C@@H](C)O)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(N)=O | 10.1021/jm9018349 | |||||
| CHEMBL501079 | 216618 | None | 9 | Human | Binding | pKi | = | 10.5 | 10.5 | 11 | 2 | ChEMBL | None | None | None | CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CN)[C@@H](C)O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(N)=O | 10.1021/jm9018349 | |||||
| CHEMBL526003 | 218159 | None | 24 | Human | Binding | pKi | = | 10.5 | 10.5 | 10 | 3 | ChEMBL | None | None | None | CSCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CN)[C@@H](C)O)C(N)=O | 10.1021/jm9018349 | |||||
| CHEMBL604373 | 218312 | None | 5 | Human | Binding | pKi | = | 10.1 | 10.1 | 7 | 2 | ChEMBL | None | None | None | CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](CCCNC(=N)N)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CN)[C@@H](C)O)C(N)=O | 10.1021/jm9018349 | |||||
| CHEMBL604990 | 218314 | None | 22 | Human | Binding | pKi | = | 10 | 10.0 | 15 | 2 | ChEMBL | None | None | None | CC(C)C[C@H](NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CN)[C@@H](C)O)C(=O)N[C@@H](C)C(N)=O | 10.1021/jm9018349 | |||||
| CHEMBL592413 | 218299 | None | 0 | Human | Binding | pKi | = | 9.5 | 9.5 | 4 | 2 | ChEMBL | None | None | None | CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CN)[C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O)[C@@H](C)O | 10.1021/jm9018349 | |||||
| CHEMBL501079 | 216618 | None | 9 | Human | Binding | pKi | = | 9.5 | 9.5 | 11 | 2 | ChEMBL | None | None | None | CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CN)[C@@H](C)O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(N)=O | 10.1021/jm8007618 | |||||
| 44563951 | 189045 | None | 0 | Human | Binding | pKi | = | 9.4 | 9.4 | 60 | 2 | ChEMBL | 1874 | 63 | 25 | 27 | -5.8 | CNCC(=O)O[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O | 10.1021/jm801397w | |||
| CHEMBL508036 | 189045 | None | 0 | Human | Binding | pKi | = | 9.4 | 9.4 | 60 | 2 | ChEMBL | 1874 | 63 | 25 | 27 | -5.8 | CNCC(=O)O[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O | 10.1021/jm801397w | |||
| CHEMBL525055 | 218124 | None | 0 | Human | Binding | pKi | = | 9.4 | 9.4 | 60 | 2 | ChEMBL | None | None | None | CNCC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O | 10.1021/jm801088x | |||||
| CHEMBL501079 | 216618 | None | 9 | Human | Binding | pKi | = | 9.3 | 9.3 | 11 | 2 | ChEMBL | None | None | None | CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CN)[C@@H](C)O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(N)=O | 10.1016/j.ejmech.2013.01.044 | |||||
| 44563958 | 188861 | None | 0 | Human | Binding | pKi | = | 9.3 | 9.3 | 40 | 2 | ChEMBL | 2122 | 78 | 25 | 32 | -5.9 | CNCC(=O)O[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCNC(=O)COCCOCCOCCOCCOC)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O | 10.1021/jm801397w | |||
| CHEMBL505299 | 188861 | None | 0 | Human | Binding | pKi | = | 9.3 | 9.3 | 40 | 2 | ChEMBL | 2122 | 78 | 25 | 32 | -5.9 | CNCC(=O)O[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCNC(=O)COCCOCCOCCOCCOC)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O | 10.1021/jm801397w | |||
| CHEMBL508083 | 217196 | None | 0 | Human | Binding | pKi | = | 9.3 | 9.3 | 25 | 2 | ChEMBL | None | None | None | CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CN)[C@@H](C)O)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](C)C(=O)N[C@H](C(N)=O)C(C)C | 10.1021/jm801088x | |||||
| 44563952 | 188785 | None | 0 | Human | Binding | pKi | = | 9.2 | 9.2 | 20 | 2 | ChEMBL | 2000 | 70 | 25 | 27 | -3.2 | CCCCCCCC(=O)NCCCC[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)OC(=O)CNC)[C@@H](C)O)C(=O)N[C@@H](CCCCN)C(N)=O | 10.1021/jm801397w | |||
| CHEMBL503900 | 188785 | None | 0 | Human | Binding | pKi | = | 9.2 | 9.2 | 20 | 2 | ChEMBL | 2000 | 70 | 25 | 27 | -3.2 | CCCCCCCC(=O)NCCCC[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)OC(=O)CNC)[C@@H](C)O)C(=O)N[C@@H](CCCCN)C(N)=O | 10.1021/jm801397w | |||
| 25180491 | 193560 | None | 0 | Human | Binding | pKi | = | 9.1 | 9.1 | 16 | 2 | ChEMBL | 2111 | 78 | 26 | 26 | -0.5 | CCCCCCCCCCCCCCCC(=O)NCCCC[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H](CCCCN)NC(=O)[C@H]1CCCN1C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CNC)[C@@H](C)O)C(=O)N[C@@H](CCCCN)C(N)=O | 10.1021/jm801088x | |||
| CHEMBL526500 | 193560 | None | 0 | Human | Binding | pKi | = | 9.1 | 9.1 | 16 | 2 | ChEMBL | 2111 | 78 | 26 | 26 | -0.5 | CCCCCCCCCCCCCCCC(=O)NCCCC[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H](CCCCN)NC(=O)[C@H]1CCCN1C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CNC)[C@@H](C)O)C(=O)N[C@@H](CCCCN)C(N)=O | 10.1021/jm801088x | |||
| 44563953 | 176905 | None | 0 | Human | Binding | pKi | = | 8.9 | 8.9 | 11 | 2 | ChEMBL | 2028 | 72 | 25 | 27 | -2.5 | CCCCCCCCCC(=O)NCCCC[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)OC(=O)CNC)[C@@H](C)O)C(=O)N[C@@H](CCCCN)C(N)=O | 10.1021/jm801397w | |||
| CHEMBL460706 | 176905 | None | 0 | Human | Binding | pKi | = | 8.9 | 8.9 | 11 | 2 | ChEMBL | 2028 | 72 | 25 | 27 | -2.5 | CCCCCCCCCC(=O)NCCCC[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)OC(=O)CNC)[C@@H](C)O)C(=O)N[C@@H](CCCCN)C(N)=O | 10.1021/jm801397w | |||
| 44563954 | 189020 | None | 0 | Human | Binding | pKi | = | 8.9 | 8.9 | 11 | 2 | ChEMBL | 2056 | 74 | 25 | 27 | -1.7 | CCCCCCCCCCCC(=O)NCCCC[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)OC(=O)CNC)[C@@H](C)O)C(=O)N[C@@H](CCCCN)C(N)=O | 10.1021/jm801397w | |||
| CHEMBL507733 | 189020 | None | 0 | Human | Binding | pKi | = | 8.9 | 8.9 | 11 | 2 | ChEMBL | 2056 | 74 | 25 | 27 | -1.7 | CCCCCCCCCCCC(=O)NCCCC[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)OC(=O)CNC)[C@@H](C)O)C(=O)N[C@@H](CCCCN)C(N)=O | 10.1021/jm801397w | |||
| 45104656 | 201028 | None | 0 | Human | Binding | pKi | = | 8.8 | 8.8 | 9 | 2 | ChEMBL | 2082 | 76 | 25 | 25 | 0.3 | CCCCCCCCCCCCCCCC(=O)NCCCC[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(C)=O)[C@@H](C)O)C(=O)N[C@@H](CCCCN)C(N)=O | 10.1021/jm9018349 | |||
| CHEMBL578317 | 201028 | None | 0 | Human | Binding | pKi | = | 8.8 | 8.8 | 9 | 2 | ChEMBL | 2082 | 76 | 25 | 25 | 0.3 | CCCCCCCCCCCCCCCC(=O)NCCCC[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(C)=O)[C@@H](C)O)C(=O)N[C@@H](CCCCN)C(N)=O | 10.1021/jm9018349 | |||
| 25180487 | 193511 | None | 0 | Human | Binding | pKi | = | 8.7 | 8.7 | 11 | 2 | ChEMBL | 2111 | 78 | 26 | 26 | -0.5 | CCCCCCCCCCCCCCCC(=O)NCCCC[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CNC)[C@@H](C)O)C(N)=O | 10.1021/jm801088x | |||
| CHEMBL525755 | 193511 | None | 0 | Human | Binding | pKi | = | 8.7 | 8.7 | 11 | 2 | ChEMBL | 2111 | 78 | 26 | 26 | -0.5 | CCCCCCCCCCCCCCCC(=O)NCCCC[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CNC)[C@@H](C)O)C(N)=O | 10.1021/jm801088x | |||
| 45104655 | 201083 | None | 0 | Human | Binding | pKi | = | 8.0 | 8.0 | 3 | 2 | ChEMBL | 2111 | 77 | 26 | 26 | -0.4 | CCCCCCCCCCCCCCCC(=O)NCCCC[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](C)N)[C@@H](C)O)C(=O)N[C@@H](CCCCN)C(N)=O | 10.1021/jm9018349 | |||
| CHEMBL578910 | 201083 | None | 0 | Human | Binding | pKi | = | 8.0 | 8.0 | 3 | 2 | ChEMBL | 2111 | 77 | 26 | 26 | -0.4 | CCCCCCCCCCCCCCCC(=O)NCCCC[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](C)N)[C@@H](C)O)C(=O)N[C@@H](CCCCN)C(N)=O | 10.1021/jm9018349 | |||
| 71717271 | 86124 | None | 0 | Human | Binding | pKi | = | 4.9 | 4.9 | 1 | 3 | ChEMBL | 678 | 13 | 4 | 7 | 6.5 | Cc1cc(=O)oc2cc(NC(=O)[C@@H](CCCCN)NC(=O)[C@H](CC3CCCCC3)NC(=O)OCC3c4ccccc4-c4ccccc43)ccc12 | 10.1021/jm9018349 | |||
| CHEMBL2309599 | 86124 | None | 0 | Human | Binding | pKi | = | 4.9 | 4.9 | 1 | 3 | ChEMBL | 678 | 13 | 4 | 7 | 6.5 | Cc1cc(=O)oc2cc(NC(=O)[C@@H](CCCCN)NC(=O)[C@H](CC3CCCCC3)NC(=O)OCC3c4ccccc4-c4ccccc43)ccc12 | 10.1021/jm9018349 | |||
| 44563955 | 193451 | None | 0 | Human | Binding | pKi | = | 8.6 | 8.6 | 7 | 2 | ChEMBL | 2084 | 76 | 25 | 27 | -0.9 | CCCCCCCCCCCCCC(=O)NCCCC[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)OC(=O)CNC)[C@@H](C)O)C(=O)N[C@@H](CCCCN)C(N)=O | 10.1021/jm801397w | |||
| CHEMBL524678 | 193451 | None | 0 | Human | Binding | pKi | = | 8.6 | 8.6 | 7 | 2 | ChEMBL | 2084 | 76 | 25 | 27 | -0.9 | CCCCCCCCCCCCCC(=O)NCCCC[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)OC(=O)CNC)[C@@H](C)O)C(=O)N[C@@H](CCCCN)C(N)=O | 10.1021/jm801397w | |||
| 25180489 | 188367 | None | 0 | Human | Binding | pKi | = | 8.6 | 8.6 | 5 | 2 | ChEMBL | 2097 | 77 | 26 | 26 | -0.8 | CCCCCCCCCCCCCCCC(=O)NCCCC[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CN)[C@@H](C)O)C(=O)N[C@@H](CCCCN)C(N)=O | 10.1021/jm9018349 | |||
| CHEMBL499807 | 188367 | None | 0 | Human | Binding | pKi | = | 8.6 | 8.6 | 5 | 2 | ChEMBL | 2097 | 77 | 26 | 26 | -0.8 | CCCCCCCCCCCCCCCC(=O)NCCCC[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CN)[C@@H](C)O)C(=O)N[C@@H](CCCCN)C(N)=O | 10.1021/jm9018349 | |||
| 25180496 | 188828 | None | 0 | Human | Binding | pKi | = | 7.7 | 7.7 | 2 | 2 | ChEMBL | 2153 | 81 | 26 | 26 | 0.8 | CCCCCCCCCCCCCCCC(=O)NCCCC[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CCCCCN)[C@@H](C)O)C(=O)N[C@@H](CCCCN)C(N)=O | 10.1021/jm801088x | |||
| CHEMBL504758 | 188828 | None | 0 | Human | Binding | pKi | = | 7.7 | 7.7 | 2 | 2 | ChEMBL | 2153 | 81 | 26 | 26 | 0.8 | CCCCCCCCCCCCCCCC(=O)NCCCC[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CCCCCN)[C@@H](C)O)C(=O)N[C@@H](CCCCN)C(N)=O | 10.1021/jm801088x | |||
| 25180488 | 188473 | None | 0 | Human | Binding | pKi | = | 7.6 | 7.6 | 4 | 2 | ChEMBL | 2111 | 78 | 26 | 26 | -0.5 | CCCCCCCCCCCCCCCC(=O)NCCCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CNC)[C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O | 10.1021/jm801088x | |||
| CHEMBL501306 | 188473 | None | 0 | Human | Binding | pKi | = | 7.6 | 7.6 | 4 | 2 | ChEMBL | 2111 | 78 | 26 | 26 | -0.5 | CCCCCCCCCCCCCCCC(=O)NCCCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CNC)[C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O | 10.1021/jm801088x | |||
| 25180492 | 188999 | None | 0 | Human | Binding | pKi | = | 7.6 | 7.6 | 2 | 2 | ChEMBL | 2014 | 77 | 26 | 25 | -0.5 | CCCCCCCCCCCCCCCC(=O)NCCCC[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CNC)[C@@H](C)O)C(=O)N[C@@H](CCCCN)C(N)=O | 10.1021/jm801088x | |||
| CHEMBL507373 | 188999 | None | 0 | Human | Binding | pKi | = | 7.6 | 7.6 | 2 | 2 | ChEMBL | 2014 | 77 | 26 | 25 | -0.5 | CCCCCCCCCCCCCCCC(=O)NCCCC[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CNC)[C@@H](C)O)C(=O)N[C@@H](CCCCN)C(N)=O | 10.1021/jm801088x | |||
| 25180490 | 63205 | None | 0 | Human | Binding | pKi | = | 8.5 | 8.5 | 19 | 2 | ChEMBL | 2195 | 78 | 32 | 26 | -3.1 | CCCCCCCCCCCCCCCC(=O)NCCCC[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CNC)[C@@H](C)O)C(=O)N[C@@H](CCCNC(=N)N)C(N)=O | 10.1021/jm801088x | |||
| 91934869 | 63205 | None | 0 | Human | Binding | pKi | = | 8.5 | 8.5 | 19 | 2 | ChEMBL | 2195 | 78 | 32 | 26 | -3.1 | CCCCCCCCCCCCCCCC(=O)NCCCC[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CNC)[C@@H](C)O)C(=O)N[C@@H](CCCNC(=N)N)C(N)=O | 10.1021/jm801088x | |||
| CHEMBL1790054 | 63205 | None | 0 | Human | Binding | pKi | = | 8.5 | 8.5 | 19 | 2 | ChEMBL | 2195 | 78 | 32 | 26 | -3.1 | CCCCCCCCCCCCCCCC(=O)NCCCC[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CNC)[C@@H](C)O)C(=O)N[C@@H](CCCNC(=N)N)C(N)=O | 10.1021/jm801088x | |||
| 24760995 | 201043 | None | 0 | Human | Binding | pKi | = | 8.5 | 8.5 | 14 | 2 | ChEMBL | 2112 | 78 | 26 | 26 | 0.1 | CCCCCCCCCCCCCCCC(=O)NCCCC[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CNC)[C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)O | 10.1021/jm9018349 | |||
| CHEMBL578514 | 201043 | None | 0 | Human | Binding | pKi | = | 8.5 | 8.5 | 14 | 2 | ChEMBL | 2112 | 78 | 26 | 26 | 0.1 | CCCCCCCCCCCCCCCC(=O)NCCCC[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CNC)[C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)O | 10.1021/jm9018349 | |||
| 24760995 | 201043 | None | 0 | Human | Binding | pKi | = | 8.5 | 8.5 | 14 | 2 | ChEMBL | 2112 | 78 | 26 | 26 | 0.1 | CCCCCCCCCCCCCCCC(=O)NCCCC[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CNC)[C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)O | 10.1021/jm9018349 | |||
| CHEMBL578514 | 201043 | None | 0 | Human | Binding | pKi | = | 8.5 | 8.5 | 14 | 2 | ChEMBL | 2112 | 78 | 26 | 26 | 0.1 | CCCCCCCCCCCCCCCC(=O)NCCCC[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CNC)[C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)O | 10.1021/jm9018349 | |||
| 44563956 | 188997 | None | 0 | Human | Binding | pKi | = | 8.5 | 8.5 | 14 | 2 | ChEMBL | 2112 | 78 | 25 | 27 | -0.1 | CCCCCCCCCCCCCCCC(=O)NCCCC[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)OC(=O)CNC)[C@@H](C)O)C(=O)N[C@@H](CCCCN)C(N)=O | 10.1021/jm801397w | |||
| CHEMBL507353 | 188997 | None | 0 | Human | Binding | pKi | = | 8.5 | 8.5 | 14 | 2 | ChEMBL | 2112 | 78 | 25 | 27 | -0.1 | CCCCCCCCCCCCCCCC(=O)NCCCC[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)OC(=O)CNC)[C@@H](C)O)C(=O)N[C@@H](CCCCN)C(N)=O | 10.1021/jm801397w | |||
| 44587984 | 193473 | None | 4 | Human | Binding | pKi | = | 8.5 | 8.5 | 14 | 2 | ChEMBL | 2111 | 78 | 26 | 26 | -0.5 | CCCCCCCCCCCCCCCC(=O)NCCCC[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CNC)[C@@H](C)O)C(=O)N[C@@H](CCCCN)C(N)=O | 10.1021/jm801088x | |||
| CHEMBL525023 | 193473 | None | 4 | Human | Binding | pKi | = | 8.5 | 8.5 | 14 | 2 | ChEMBL | 2111 | 78 | 26 | 26 | -0.5 | CCCCCCCCCCCCCCCC(=O)NCCCC[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CNC)[C@@H](C)O)C(=O)N[C@@H](CCCCN)C(N)=O | 10.1021/jm801088x | |||
| CHEMBL2324950 | 211987 | None | 0 | Human | Binding | pKi | = | 8.4 | 8.4 | 4 | 2 | ChEMBL | None | None | None | CNCC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@]1(C)CCC/C=C\CCC[C@@](C)(C(=O)N[C@@H](CCCCN)C(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC1=O)[C@@H](C)O | 10.1016/j.bmc.2012.10.026 | |||||
| 25180498 | 193465 | None | 0 | Human | Binding | pKi | = | 6.5 | 6.5 | 4 | 2 | ChEMBL | 1957 | 75 | 25 | 24 | 0.3 | CCCCCCCCCCCCCCCC(=O)NCCCC[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CNC)[C@@H](C)O)C(=O)N[C@@H](CCCCN)C(N)=O | 10.1021/jm801088x | |||
| CHEMBL524892 | 193465 | None | 0 | Human | Binding | pKi | = | 6.5 | 6.5 | 4 | 2 | ChEMBL | 1957 | 75 | 25 | 24 | 0.3 | CCCCCCCCCCCCCCCC(=O)NCCCC[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CNC)[C@@H](C)O)C(=O)N[C@@H](CCCCN)C(N)=O | 10.1021/jm801088x | |||
| 24748735 | 1755 | None | 2 | Human | Binding | pKi | = | 4.5 | 4.5 | -3 | 2 | ChEMBL | 988 | 12 | 7 | 15 | 4.2 | NCCCC[C@@H](C(=O)OC)NC(=O)[C@]1(C)NC(=O)c2nc(oc2C)[C@@](C)(NC(=O)c2nc([C@](NC(=O)c3nc1oc3C)(C)C(=O)NCC1CCCCC1)oc2C)C(=O)NC1c2ccccc2c2c1cccc2 | 10.1021/jm9018349 | |||
| 6119 | 1755 | None | 2 | Human | Binding | pKi | = | 4.5 | 4.5 | -3 | 2 | ChEMBL | 988 | 12 | 7 | 15 | 4.2 | NCCCC[C@@H](C(=O)OC)NC(=O)[C@]1(C)NC(=O)c2nc(oc2C)[C@@](C)(NC(=O)c2nc([C@](NC(=O)c3nc1oc3C)(C)C(=O)NCC1CCCCC1)oc2C)C(=O)NC1c2ccccc2c2c1cccc2 | 10.1021/jm9018349 | |||
| CHEMBL1187471 | 1755 | None | 2 | Human | Binding | pKi | = | 4.5 | 4.5 | -3 | 2 | ChEMBL | 988 | 12 | 7 | 15 | 4.2 | NCCCC[C@@H](C(=O)OC)NC(=O)[C@]1(C)NC(=O)c2nc(oc2C)[C@@](C)(NC(=O)c2nc([C@](NC(=O)c3nc1oc3C)(C)C(=O)NCC1CCCCC1)oc2C)C(=O)NC1c2ccccc2c2c1cccc2 | 10.1021/jm9018349 | |||
| 45104657 | 203918 | None | 0 | Human | Binding | pKi | = | 6.4 | 6.4 | -18 | 2 | ChEMBL | 2054 | 76 | 25 | 25 | 0.3 | CCCCCCCCCCCCCCCC(=O)NCCCC[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC)[C@@H](C)O)C(=O)N[C@@H](CCCCN)C(N)=O | 10.1021/jm9018349 | |||
| CHEMBL604991 | 203918 | None | 0 | Human | Binding | pKi | = | 6.4 | 6.4 | -18 | 2 | ChEMBL | 2054 | 76 | 25 | 25 | 0.3 | CCCCCCCCCCCCCCCC(=O)NCCCC[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC)[C@@H](C)O)C(=O)N[C@@H](CCCCN)C(N)=O | 10.1021/jm9018349 | |||
| CHEMBL2324949 | 211986 | None | 0 | Human | Binding | pKi | = | 7.4 | 7.4 | 3 | 2 | ChEMBL | None | None | None | CNCC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@]1(C)CCC/C=C/CCC[C@@](C)(C(=O)NCC(=O)N2CCC[C@H]2C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)CNC1=O)[C@@H](C)O | 10.1016/j.bmc.2012.10.026 | |||||
| 25180495 | 188940 | None | 0 | Human | Binding | pKi | = | 6.4 | 6.4 | -8 | 2 | ChEMBL | 2040 | 75 | 25 | 25 | 0.1 | CCCCCCCCCCCCCCCC(=O)NCCCC[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)[C@@H](C)O)C(=O)N[C@@H](CCCCN)C(N)=O | 10.1021/jm9018349 | |||
| CHEMBL506495 | 188940 | None | 0 | Human | Binding | pKi | = | 6.4 | 6.4 | -8 | 2 | ChEMBL | 2040 | 75 | 25 | 25 | 0.1 | CCCCCCCCCCCCCCCC(=O)NCCCC[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)[C@@H](C)O)C(=O)N[C@@H](CCCCN)C(N)=O | 10.1021/jm9018349 | |||
| 25180495 | 188940 | None | 0 | Human | Binding | pKi | = | 6.4 | 6.4 | -8 | 2 | ChEMBL | 2040 | 75 | 25 | 25 | 0.1 | CCCCCCCCCCCCCCCC(=O)NCCCC[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)[C@@H](C)O)C(=O)N[C@@H](CCCCN)C(N)=O | 10.1021/jm801088x | |||
| CHEMBL506495 | 188940 | None | 0 | Human | Binding | pKi | = | 6.4 | 6.4 | -8 | 2 | ChEMBL | 2040 | 75 | 25 | 25 | 0.1 | CCCCCCCCCCCCCCCC(=O)NCCCC[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)[C@@H](C)O)C(=O)N[C@@H](CCCCN)C(N)=O | 10.1021/jm801088x | |||
| 44563957 | 172845 | None | 0 | Human | Binding | pKi | = | 8.4 | 8.4 | 3 | 2 | ChEMBL | 2140 | 80 | 25 | 27 | 0.7 | CCCCCCCCCCCCCCCCCC(=O)NCCCC[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)OC(=O)CNC)[C@@H](C)O)C(=O)N[C@@H](CCCCN)C(N)=O | 10.1021/jm801397w | |||
| CHEMBL450827 | 172845 | None | 0 | Human | Binding | pKi | = | 8.4 | 8.4 | 3 | 2 | ChEMBL | 2140 | 80 | 25 | 27 | 0.7 | CCCCCCCCCCCCCCCCCC(=O)NCCCC[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)OC(=O)CNC)[C@@H](C)O)C(=O)N[C@@H](CCCCN)C(N)=O | 10.1021/jm801397w | |||
| 25180497 | 193693 | None | 0 | Human | Binding | pKi | = | 7.4 | 7.4 | 5 | 2 | ChEMBL | 2213 | 87 | 29 | 28 | -0.4 | CCCCCCCCCCCCCCCC(=O)NCCCC[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CNC)[C@@H](C)O)C(=O)N[C@@H](CCCCN)C(N)=O | 10.1021/jm801088x | |||
| CHEMBL526889 | 193693 | None | 0 | Human | Binding | pKi | = | 7.4 | 7.4 | 5 | 2 | ChEMBL | 2213 | 87 | 29 | 28 | -0.4 | CCCCCCCCCCCCCCCC(=O)NCCCC[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CNC)[C@@H](C)O)C(=O)N[C@@H](CCCCN)C(N)=O | 10.1021/jm801088x | |||
| 25180489 | 188367 | None | 0 | Human | Binding | pKi | = | 8.3 | 8.3 | 5 | 2 | ChEMBL | 2097 | 77 | 26 | 26 | -0.8 | CCCCCCCCCCCCCCCC(=O)NCCCC[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CN)[C@@H](C)O)C(=O)N[C@@H](CCCCN)C(N)=O | 10.1021/jm801088x | |||
| CHEMBL499807 | 188367 | None | 0 | Human | Binding | pKi | = | 8.3 | 8.3 | 5 | 2 | ChEMBL | 2097 | 77 | 26 | 26 | -0.8 | CCCCCCCCCCCCCCCC(=O)NCCCC[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CN)[C@@H](C)O)C(=O)N[C@@H](CCCCN)C(N)=O | 10.1021/jm801088x | |||
| CHEMBL592415 | 218300 | None | 0 | Human | Binding | pKi | = | 7.3 | 7.3 | -5 | 2 | ChEMBL | None | None | None | None | 10.1021/jm9018349 | |||||
| CHEMBL592170 | 218298 | None | 0 | Human | Binding | pKi | = | 6.3 | 6.3 | -2 | 2 | ChEMBL | None | None | None | CC(C)C[C@H](NC(=O)CNC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CC(N)=O)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CN)[C@@H](C)O)C(C)C)C(=O)N[C@H](C(=O)N[C@@H](CO)C(N)=O)[C@@H](C)O | 10.1021/jm9018349 | |||||
| 25180494 | 188837 | None | 0 | Human | Binding | pKi | = | 8.2 | 8.2 | 4 | 2 | ChEMBL | 2111 | 78 | 26 | 26 | -0.5 | CCCCCCCCCCCCCCCC(=O)NCCCC[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CNC)[C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O | 10.1021/jm801088x | |||
| CHEMBL504914 | 188837 | None | 0 | Human | Binding | pKi | = | 8.2 | 8.2 | 4 | 2 | ChEMBL | 2111 | 78 | 26 | 26 | -0.5 | CCCCCCCCCCCCCCCC(=O)NCCCC[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CNC)[C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O | 10.1021/jm801088x | |||
| 25180486 | 193684 | None | 0 | Human | Binding | pKi | = | 7.1 | 7.1 | 1 | 2 | ChEMBL | 1935 | 66 | 23 | 23 | -0.4 | CCCCCCCCCCCCCCCC(=O)NCCCC[C@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CNC)[C@@H](C)O)C(N)=O | 10.1021/jm801088x | |||
| 44587983 | 193684 | None | 0 | Human | Binding | pKi | = | 7.1 | 7.1 | 1 | 2 | ChEMBL | 1935 | 66 | 23 | 23 | -0.4 | CCCCCCCCCCCCCCCC(=O)NCCCC[C@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CNC)[C@@H](C)O)C(N)=O | 10.1021/jm801088x | |||
| CHEMBL526862 | 193684 | None | 0 | Human | Binding | pKi | = | 7.1 | 7.1 | 1 | 2 | ChEMBL | 1935 | 66 | 23 | 23 | -0.4 | CCCCCCCCCCCCCCCC(=O)NCCCC[C@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CNC)[C@@H](C)O)C(N)=O | 10.1021/jm801088x | |||
| CHEMBL578710 | 218268 | None | 22 | Human | Binding | pKi | = | 6.1 | 6.1 | -501 | 2 | ChEMBL | None | None | None | CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)[C@@H](C)O)C(N)=O | 10.1021/jm9018349 | |||||
| 155817484 | 1714 | None | 0 | Rat | Binding | pKd | = | 10.1 | 10.1 | -1 | 6 | Guide to Pharmacology | None | None | None | None | 8562318 | |||||
| 155817484 | 1714 | None | 0 | Rat | Binding | pKd | = | 10.1 | 10.1 | -1 | 6 | Guide to Pharmacology | None | None | None | None | 8750821 | |||||
| 155817484 | 1714 | None | 0 | Rat | Binding | pKd | = | 10.1 | 10.1 | -1 | 6 | Guide to Pharmacology | None | None | None | None | 9305929 | |||||
| 155817484 | 1714 | None | 0 | Rat | Binding | pKd | = | 10.1 | 10.1 | -1 | 6 | Guide to Pharmacology | None | None | None | None | 9578584 | |||||
| 155817484 | 1714 | None | 0 | Rat | Binding | pKd | = | 10.1 | 10.1 | -1 | 6 | Guide to Pharmacology | None | None | None | None | 9685625 | |||||
| 155817484 | 1714 | None | 0 | Rat | Binding | pKd | = | 10.1 | 10.1 | -1 | 6 | Guide to Pharmacology | None | None | None | None | 9722565 | |||||
| 6117 | 1714 | None | 0 | Rat | Binding | pKd | = | 10.1 | 10.1 | -1 | 6 | Guide to Pharmacology | None | None | None | None | 8562318 | |||||
| 6117 | 1714 | None | 0 | Rat | Binding | pKd | = | 10.1 | 10.1 | -1 | 6 | Guide to Pharmacology | None | None | None | None | 8750821 | |||||
| 6117 | 1714 | None | 0 | Rat | Binding | pKd | = | 10.1 | 10.1 | -1 | 6 | Guide to Pharmacology | None | None | None | None | 9305929 | |||||
| 6117 | 1714 | None | 0 | Rat | Binding | pKd | = | 10.1 | 10.1 | -1 | 6 | Guide to Pharmacology | None | None | None | None | 9578584 | |||||
| 6117 | 1714 | None | 0 | Rat | Binding | pKd | = | 10.1 | 10.1 | -1 | 6 | Guide to Pharmacology | None | None | None | None | 9685625 | |||||
| 6117 | 1714 | None | 0 | Rat | Binding | pKd | = | 10.1 | 10.1 | -1 | 6 | Guide to Pharmacology | None | None | None | None | 9722565 | |||||
| 6129 | 1714 | None | 0 | Rat | Binding | pKd | = | 10.1 | 10.1 | -1 | 6 | Guide to Pharmacology | None | None | None | None | 8562318 | |||||
| 6129 | 1714 | None | 0 | Rat | Binding | pKd | = | 10.1 | 10.1 | -1 | 6 | Guide to Pharmacology | None | None | None | None | 8750821 | |||||
| 6129 | 1714 | None | 0 | Rat | Binding | pKd | = | 10.1 | 10.1 | -1 | 6 | Guide to Pharmacology | None | None | None | None | 9305929 | |||||
| 6129 | 1714 | None | 0 | Rat | Binding | pKd | = | 10.1 | 10.1 | -1 | 6 | Guide to Pharmacology | None | None | None | None | 9578584 | |||||
| 6129 | 1714 | None | 0 | Rat | Binding | pKd | = | 10.1 | 10.1 | -1 | 6 | Guide to Pharmacology | None | None | None | None | 9685625 | |||||
| 6129 | 1714 | None | 0 | Rat | Binding | pKd | = | 10.1 | 10.1 | -1 | 6 | Guide to Pharmacology | None | None | None | None | 9722565 | |||||
| 6098 | 3709 | None | 0 | Rat | Binding | pKd | = | 5.8 | 5.8 | - | 1 | Guide to Pharmacology | None | None | None | None | 8738882 | |||||
| 6085 | 1722 | None | 0 | Rat | Binding | pKd | = | 6.9 | 6.9 | - | 1 | Guide to Pharmacology | None | None | None | None | 8738882 | |||||
| 6096 | 1759 | None | 0 | Rat | Binding | pKd | = | 8.2 | 8.2 | - | 1 | Guide to Pharmacology | None | None | None | None | 8738882 | |||||
| 155817484 | 1714 | None | 0 | Human | Binding | pKd | = | 9.1 | 9.1 | 1 | 6 | Guide to Pharmacology | None | None | None | None | 7524088 | |||||
| 6117 | 1714 | None | 0 | Human | Binding | pKd | = | 9.1 | 9.1 | 1 | 6 | Guide to Pharmacology | None | None | None | None | 7524088 | |||||
| 6129 | 1714 | None | 0 | Human | Binding | pKd | = | 9.1 | 9.1 | 1 | 6 | Guide to Pharmacology | None | None | None | None | 7524088 | |||||
| 155817484 | 1714 | None | 0 | Rat | Binding | pKd | = | 9.1 | 9.1 | -1 | 6 | Guide to Pharmacology | None | None | None | None | 8738882 | |||||
| 6117 | 1714 | None | 0 | Rat | Binding | pKd | = | 9.1 | 9.1 | -1 | 6 | Guide to Pharmacology | None | None | None | None | 8738882 | |||||
| 6129 | 1714 | None | 0 | Rat | Binding | pKd | = | 9.1 | 9.1 | -1 | 6 | Guide to Pharmacology | None | None | None | None | 8738882 | |||||
| 6097 | 3708 | None | 0 | Rat | Binding | pKd | = | 9.2 | 9.2 | - | 1 | Guide to Pharmacology | None | None | None | None | 8738882 | |||||
| 155817484 | 1714 | None | 0 | Human | Binding | pKd | = | 9.8 | 9.8 | 1 | 6 | Guide to Pharmacology | None | None | None | None | 9880084 | |||||
| 6117 | 1714 | None | 0 | Human | Binding | pKd | = | 9.8 | 9.8 | 1 | 6 | Guide to Pharmacology | None | None | None | None | 9880084 | |||||
| 6129 | 1714 | None | 0 | Human | Binding | pKd | = | 9.8 | 9.8 | 1 | 6 | Guide to Pharmacology | None | None | None | None | 9880084 | |||||
| None | 218550 | 125I-GALANIN | 0 | Human | Binding | pKi | = | 9.6 | 9.6 | -11 | 6 | PDSP KiDatabase | 418 | 8 | 0 | 4 | 4.3 | CC1=CC=C(C=C1)OCCN(C2=CC=CC=C2OC)C(=O)CN3CCCCC3.Cl | None | |||
| None | 218550 | 125I-GALANIN | 0 | Rat | Binding | pKi | = | 9.2 | 9.2 | -1 | 6 | PDSP KiDatabase | 418 | 8 | 0 | 4 | 4.3 | CC1=CC=C(C=C1)OCCN(C2=CC=CC=C2OC)C(=O)CN3CCCCC3.Cl | None | |||
| None | 218550 | 125I-GALANIN | 0 | Rat | Binding | pKi | = | 9 | 9.0 | -1 | 6 | PDSP KiDatabase | 418 | 8 | 0 | 4 | 4.3 | CC1=CC=C(C=C1)OCCN(C2=CC=CC=C2OC)C(=O)CN3CCCCC3.Cl | None | |||
| None | 218550 | 125I-GALANIN | 0 | Rat | Binding | pKi | = | 8 | 8.0 | -1 | 6 | PDSP KiDatabase | 418 | 8 | 0 | 4 | 4.3 | CC1=CC=C(C=C1)OCCN(C2=CC=CC=C2OC)C(=O)CN3CCCCC3.Cl | None | |||
| None | 218550 | 125I-h Galanin | 0 | Human | Binding | pKi | = | 6.6 | 6.6 | -11 | 6 | PDSP KiDatabase | 418 | 8 | 0 | 4 | 4.3 | CC1=CC=C(C=C1)OCCN(C2=CC=CC=C2OC)C(=O)CN3CCCCC3.Cl | None | |||
| None | 218550 | 125I-h Galanin | 0 | Human | Binding | pKi | = | 7.6 | 7.6 | -11 | 6 | PDSP KiDatabase | 418 | 8 | 0 | 4 | 4.3 | CC1=CC=C(C=C1)OCCN(C2=CC=CC=C2OC)C(=O)CN3CCCCC3.Cl | None | |||
| 16131409 | 1723 | 125I-GALANIN | 0 | Rat | Binding | pKi | = | 8.5 | 8.5 | -5 | 3 | PDSP KiDatabase | None | None | None | None | None | |||||
| 6086 | 1723 | 125I-GALANIN | 0 | Rat | Binding | pKi | = | 8.5 | 8.5 | -5 | 3 | PDSP KiDatabase | None | None | None | None | None | |||||
| 155817484 | 1714 | None | 0 | Human | Binding | pKi | = | 10.1 | 10.1 | 1 | 6 | Guide to Pharmacology | None | None | None | None | 7524088 | |||||
| 155817484 | 1714 | None | 0 | Human | Binding | pKi | = | 10.1 | 10.1 | 1 | 6 | Guide to Pharmacology | None | None | None | None | 9808667 | |||||
| 155817484 | 1714 | None | 0 | Human | Binding | pKi | = | 10.1 | 10.1 | 1 | 6 | Guide to Pharmacology | None | None | None | None | 9880084 | |||||
| 6117 | 1714 | None | 0 | Human | Binding | pKi | = | 10.1 | 10.1 | 1 | 6 | Guide to Pharmacology | None | None | None | None | 7524088 | |||||
| 6117 | 1714 | None | 0 | Human | Binding | pKi | = | 10.1 | 10.1 | 1 | 6 | Guide to Pharmacology | None | None | None | None | 9808667 | |||||
| 6117 | 1714 | None | 0 | Human | Binding | pKi | = | 10.1 | 10.1 | 1 | 6 | Guide to Pharmacology | None | None | None | None | 9880084 | |||||
| 6129 | 1714 | None | 0 | Human | Binding | pKi | = | 10.1 | 10.1 | 1 | 6 | Guide to Pharmacology | None | None | None | None | 7524088 | |||||
| 6129 | 1714 | None | 0 | Human | Binding | pKi | = | 10.1 | 10.1 | 1 | 6 | Guide to Pharmacology | None | None | None | None | 9808667 | |||||
| 6129 | 1714 | None | 0 | Human | Binding | pKi | = | 10.1 | 10.1 | 1 | 6 | Guide to Pharmacology | None | None | None | None | 9880084 | |||||
| 24748735 | 1755 | None | 2 | Human | Binding | pKi | = | 4.5 | 4.5 | -3 | 2 | Guide to Pharmacology | 988 | 12 | 7 | 15 | 4.2 | NCCCC[C@@H](C(=O)OC)NC(=O)[C@]1(C)NC(=O)c2nc(oc2C)[C@@](C)(NC(=O)c2nc([C@](NC(=O)c3nc1oc3C)(C)C(=O)NCC1CCCCC1)oc2C)C(=O)NC1c2ccccc2c2c1cccc2 | 15240875 | |||
| 24748735 | 1755 | None | 2 | Human | Binding | pKi | = | 4.5 | 4.5 | -3 | 2 | Guide to Pharmacology | 988 | 12 | 7 | 15 | 4.2 | NCCCC[C@@H](C(=O)OC)NC(=O)[C@]1(C)NC(=O)c2nc(oc2C)[C@@](C)(NC(=O)c2nc([C@](NC(=O)c3nc1oc3C)(C)C(=O)NCC1CCCCC1)oc2C)C(=O)NC1c2ccccc2c2c1cccc2 | 15944006 | |||
| 6119 | 1755 | None | 2 | Human | Binding | pKi | = | 4.5 | 4.5 | -3 | 2 | Guide to Pharmacology | 988 | 12 | 7 | 15 | 4.2 | NCCCC[C@@H](C(=O)OC)NC(=O)[C@]1(C)NC(=O)c2nc(oc2C)[C@@](C)(NC(=O)c2nc([C@](NC(=O)c3nc1oc3C)(C)C(=O)NCC1CCCCC1)oc2C)C(=O)NC1c2ccccc2c2c1cccc2 | 15240875 | |||
| 6119 | 1755 | None | 2 | Human | Binding | pKi | = | 4.5 | 4.5 | -3 | 2 | Guide to Pharmacology | 988 | 12 | 7 | 15 | 4.2 | NCCCC[C@@H](C(=O)OC)NC(=O)[C@]1(C)NC(=O)c2nc(oc2C)[C@@](C)(NC(=O)c2nc([C@](NC(=O)c3nc1oc3C)(C)C(=O)NCC1CCCCC1)oc2C)C(=O)NC1c2ccccc2c2c1cccc2 | 15944006 | |||
| CHEMBL1187471 | 1755 | None | 2 | Human | Binding | pKi | = | 4.5 | 4.5 | -3 | 2 | Guide to Pharmacology | 988 | 12 | 7 | 15 | 4.2 | NCCCC[C@@H](C(=O)OC)NC(=O)[C@]1(C)NC(=O)c2nc(oc2C)[C@@](C)(NC(=O)c2nc([C@](NC(=O)c3nc1oc3C)(C)C(=O)NCC1CCCCC1)oc2C)C(=O)NC1c2ccccc2c2c1cccc2 | 15240875 | |||
| CHEMBL1187471 | 1755 | None | 2 | Human | Binding | pKi | = | 4.5 | 4.5 | -3 | 2 | Guide to Pharmacology | 988 | 12 | 7 | 15 | 4.2 | NCCCC[C@@H](C(=O)OC)NC(=O)[C@]1(C)NC(=O)c2nc(oc2C)[C@@](C)(NC(=O)c2nc([C@](NC(=O)c3nc1oc3C)(C)C(=O)NCC1CCCCC1)oc2C)C(=O)NC1c2ccccc2c2c1cccc2 | 15944006 | |||
| 6074 | 2442 | None | 0 | Human | Binding | pKi | = | 4.8 | 4.8 | -467 | 3 | Guide to Pharmacology | None | None | None | None | 23192661 | |||||
| 5311268 | 1756 | None | 0 | Human | Binding | pKi | = | 4.9 | 4.9 | 2 | 2 | Guide to Pharmacology | 678 | 13 | 4 | 7 | 6.5 | NCCCC[C@@H](C(=O)Nc1ccc2c(c1)oc(=O)cc2C)NC(=O)[C@@H](NC(=O)OCC1c2ccccc2c2c1cccc2)CC1CCCCC1 | 15240875 | |||
| 5311268 | 1756 | None | 0 | Human | Binding | pKi | = | 4.9 | 4.9 | 2 | 2 | Guide to Pharmacology | 678 | 13 | 4 | 7 | 6.5 | NCCCC[C@@H](C(=O)Nc1ccc2c(c1)oc(=O)cc2C)NC(=O)[C@@H](NC(=O)OCC1c2ccccc2c2c1cccc2)CC1CCCCC1 | 15944006 | |||
| 6118 | 1756 | None | 0 | Human | Binding | pKi | = | 4.9 | 4.9 | 2 | 2 | Guide to Pharmacology | 678 | 13 | 4 | 7 | 6.5 | NCCCC[C@@H](C(=O)Nc1ccc2c(c1)oc(=O)cc2C)NC(=O)[C@@H](NC(=O)OCC1c2ccccc2c2c1cccc2)CC1CCCCC1 | 15240875 | |||
| 6118 | 1756 | None | 0 | Human | Binding | pKi | = | 4.9 | 4.9 | 2 | 2 | Guide to Pharmacology | 678 | 13 | 4 | 7 | 6.5 | NCCCC[C@@H](C(=O)Nc1ccc2c(c1)oc(=O)cc2C)NC(=O)[C@@H](NC(=O)OCC1c2ccccc2c2c1cccc2)CC1CCCCC1 | 15944006 | |||
| CHEMBL592414 | 1756 | None | 0 | Human | Binding | pKi | = | 4.9 | 4.9 | 2 | 2 | Guide to Pharmacology | 678 | 13 | 4 | 7 | 6.5 | NCCCC[C@@H](C(=O)Nc1ccc2c(c1)oc(=O)cc2C)NC(=O)[C@@H](NC(=O)OCC1c2ccccc2c2c1cccc2)CC1CCCCC1 | 15240875 | |||
| CHEMBL592414 | 1756 | None | 0 | Human | Binding | pKi | = | 4.9 | 4.9 | 2 | 2 | Guide to Pharmacology | 678 | 13 | 4 | 7 | 6.5 | NCCCC[C@@H](C(=O)Nc1ccc2c(c1)oc(=O)cc2C)NC(=O)[C@@H](NC(=O)OCC1c2ccccc2c2c1cccc2)CC1CCCCC1 | 15944006 | |||
| 6103 | 2440 | None | 0 | Human | Binding | pKi | = | 5.6 | 5.6 | -64 | 3 | Guide to Pharmacology | None | None | None | None | 21333705 | |||||
| 6104 | 2441 | None | 0 | Human | Binding | pKi | = | 5.7 | 5.7 | -380 | 3 | Guide to Pharmacology | None | None | None | None | 21333705 | |||||
| 11758032 | 3545 | None | 0 | Human | Binding | pKi | = | 5.8 | 5.8 | - | 1 | Guide to Pharmacology | 584 | 5 | 3 | 12 | 0.8 | COC(=O)C1=C[C@@H](O)[C@H]([C@@H]([C@@H]1Oc1c(Cl)c(C)c(c2c1C(=O)[C@@]1(O2)C(=CC(=O)C=C1C(=O)OC)OC)Cl)O)O | None | |||
| 6128 | 3545 | None | 0 | Human | Binding | pKi | = | 5.8 | 5.8 | - | 1 | Guide to Pharmacology | 584 | 5 | 3 | 12 | 0.8 | COC(=O)C1=C[C@@H](O)[C@H]([C@@H]([C@@H]1Oc1c(Cl)c(C)c(c2c1C(=O)[C@@]1(O2)C(=CC(=O)C=C1C(=O)OC)OC)Cl)O)O | None | |||
| 6095 | 1739 | None | 0 | Rat | Binding | pKi | = | 6.2 | 6.2 | -45 | 6 | Guide to Pharmacology | None | None | None | None | 9305929 | |||||
| 6095 | 1739 | None | 0 | Rat | Binding | pKi | = | 6.2 | 6.2 | -45 | 6 | Guide to Pharmacology | None | None | None | None | 9722565 | |||||
| 6095 | 1739 | None | 0 | Human | Binding | pKi | = | 6.2 | 6.2 | -45 | 6 | Guide to Pharmacology | None | None | None | None | 9880084 | |||||
| 6101 | 2438 | None | 0 | Human | Binding | pKi | = | 6.2 | 6.2 | -89 | 3 | Guide to Pharmacology | None | None | None | None | 19467704 | |||||
| 3900 | 2451 | None | 0 | Human | Binding | pKi | = | 6.4 | 6.4 | -31 | 3 | Guide to Pharmacology | None | None | None | None | None | |||||
| 6107 | 1752 | None | 0 | Human | Binding | pKi | = | 6.4 | 6.4 | -8 | 2 | Guide to Pharmacology | None | None | None | None | 19053761 | |||||
| 6109 | 2832 | None | 0 | Human | Binding | pKi | = | 6.4 | 6.4 | -17 | 2 | Guide to Pharmacology | None | None | None | None | 20121116 | |||||
| 155817465 | 1730 | None | 0 | Rat | Binding | pKi | = | 6.5 | 6.5 | -331 | 6 | Guide to Pharmacology | None | None | None | None | 9281594 | |||||
| 155817465 | 1730 | None | 0 | Rat | Binding | pKi | = | 6.5 | 6.5 | -331 | 6 | Guide to Pharmacology | None | None | None | None | 9405385 | |||||
| 155817465 | 1730 | None | 0 | Rat | Binding | pKi | = | 6.5 | 6.5 | -331 | 6 | Guide to Pharmacology | None | None | None | None | 9742938 | |||||
| 3876 | 1730 | None | 0 | Rat | Binding | pKi | = | 6.5 | 6.5 | -331 | 6 | Guide to Pharmacology | None | None | None | None | 9281594 | |||||
| 3876 | 1730 | None | 0 | Rat | Binding | pKi | = | 6.5 | 6.5 | -331 | 6 | Guide to Pharmacology | None | None | None | None | 9405385 | |||||
| 3876 | 1730 | None | 0 | Rat | Binding | pKi | = | 6.5 | 6.5 | -331 | 6 | Guide to Pharmacology | None | None | None | None | 9742938 | |||||
| 6075 | 2108 | None | 0 | Human | Binding | pKi | = | 6.9 | 6.9 | -6 | 3 | Guide to Pharmacology | None | None | None | None | 23600864 | |||||
| 6102 | 2439 | None | 0 | Human | Binding | pKi | = | 7.0 | 7.0 | -3 | 3 | Guide to Pharmacology | None | None | None | None | 21333705 | |||||
| 101927062 | 1716 | None | 20 | Human | Binding | pKi | = | 7.3 | 7.3 | -10 | 6 | Guide to Pharmacology | None | None | None | None | 11983932 | |||||
| 155817445 | 1716 | None | 20 | Human | Binding | pKi | = | 7.3 | 7.3 | -10 | 6 | Guide to Pharmacology | None | None | None | None | 11983932 | |||||
| 16133823 | 1716 | None | 20 | Human | Binding | pKi | = | 7.3 | 7.3 | -10 | 6 | Guide to Pharmacology | None | None | None | None | 11983932 | |||||
| 3592 | 1716 | None | 20 | Human | Binding | pKi | = | 7.3 | 7.3 | -10 | 6 | Guide to Pharmacology | None | None | None | None | 11983932 | |||||
| 44584852 | 1716 | None | 20 | Human | Binding | pKi | = | 7.3 | 7.3 | -10 | 6 | Guide to Pharmacology | None | None | None | None | 11983932 | |||||
| 6090 | 1716 | None | 20 | Human | Binding | pKi | = | 7.3 | 7.3 | -10 | 6 | Guide to Pharmacology | None | None | None | None | 11983932 | |||||
| 91898917 | 1716 | None | 20 | Human | Binding | pKi | = | 7.3 | 7.3 | -10 | 6 | Guide to Pharmacology | None | None | None | None | 11983932 | |||||
| CHEMBL506553 | 1716 | None | 20 | Human | Binding | pKi | = | 7.3 | 7.3 | -10 | 6 | Guide to Pharmacology | None | None | None | None | 11983932 | |||||
| 155817465 | 1730 | None | 0 | Mouse | Binding | pKi | = | 7.5 | 7.5 | -33 | 6 | Guide to Pharmacology | None | None | None | None | 9271210 | |||||
| 155817465 | 1730 | None | 0 | Mouse | Binding | pKi | = | 7.5 | 7.5 | -33 | 6 | Guide to Pharmacology | None | None | None | None | 9832122 | |||||
| 3876 | 1730 | None | 0 | Mouse | Binding | pKi | = | 7.5 | 7.5 | -33 | 6 | Guide to Pharmacology | None | None | None | None | 9271210 | |||||
| 3876 | 1730 | None | 0 | Mouse | Binding | pKi | = | 7.5 | 7.5 | -33 | 6 | Guide to Pharmacology | None | None | None | None | 9832122 | |||||
| 155817487 | 1729 | None | 0 | Human | Binding | pKi | = | 7.6 | 7.6 | -9 | 4 | Guide to Pharmacology | None | None | None | None | 9880084 | |||||
| 6130 | 1729 | None | 0 | Human | Binding | pKi | = | 7.6 | 7.6 | -9 | 4 | Guide to Pharmacology | None | None | None | None | 9880084 | |||||
| 6076 | 2109 | None | 0 | Human | Binding | pKi | = | 7.6 | 7.6 | -5 | 3 | Guide to Pharmacology | None | None | None | None | 23600864 | |||||
| 155817479 | 1736 | None | 0 | Rat | Binding | pKi | = | 7.6 | 7.6 | -9 | 6 | Guide to Pharmacology | None | None | None | None | 9722565 | |||||
| 6083 | 1736 | None | 0 | Rat | Binding | pKi | = | 7.6 | 7.6 | -9 | 6 | Guide to Pharmacology | None | None | None | None | 9722565 | |||||
| 155817487 | 1729 | None | 0 | Rat | Binding | pKi | = | 7.6 | 7.6 | -8 | 4 | Guide to Pharmacology | None | None | None | None | 8562318 | |||||
| 155817487 | 1729 | None | 0 | Rat | Binding | pKi | = | 7.6 | 7.6 | -8 | 4 | Guide to Pharmacology | None | None | None | None | 8750821 | |||||
| 6130 | 1729 | None | 0 | Rat | Binding | pKi | = | 7.6 | 7.6 | -8 | 4 | Guide to Pharmacology | None | None | None | None | 8562318 | |||||
| 6130 | 1729 | None | 0 | Rat | Binding | pKi | = | 7.6 | 7.6 | -8 | 4 | Guide to Pharmacology | None | None | None | None | 8750821 | |||||
| 155817479 | 1736 | None | 0 | Human | Binding | pKi | = | 8.2 | 8.2 | -2 | 6 | Guide to Pharmacology | None | None | None | None | 9880084 | |||||
| 6083 | 1736 | None | 0 | Human | Binding | pKi | = | 8.2 | 8.2 | -2 | 6 | Guide to Pharmacology | None | None | None | None | 9880084 | |||||
| 3899 | 2447 | None | 0 | Rat | Binding | pKi | = | 8.2 | 8.2 | -50 | 8 | Guide to Pharmacology | None | None | None | None | 8750821 | |||||
| 3899 | 2447 | None | 0 | Rat | Binding | pKi | = | 8.2 | 8.2 | -50 | 8 | Guide to Pharmacology | None | None | None | None | 9305929 | |||||
| 3899 | 2447 | None | 0 | Rat | Binding | pKi | = | 8.2 | 8.2 | -50 | 8 | Guide to Pharmacology | None | None | None | None | 9722565 | |||||
| 16131409 | 1723 | None | 0 | Rat | Binding | pKi | = | 8.2 | 8.2 | -5 | 3 | Guide to Pharmacology | None | None | None | None | 8750821 | |||||
| 16131409 | 1723 | None | 0 | Rat | Binding | pKi | = | 8.2 | 8.2 | -5 | 3 | Guide to Pharmacology | None | None | None | None | 9305929 | |||||
| 6086 | 1723 | None | 0 | Rat | Binding | pKi | = | 8.2 | 8.2 | -5 | 3 | Guide to Pharmacology | None | None | None | None | 8750821 | |||||
| 6086 | 1723 | None | 0 | Rat | Binding | pKi | = | 8.2 | 8.2 | -5 | 3 | Guide to Pharmacology | None | None | None | None | 9305929 | |||||
| 6115 | 1748 | None | 0 | Human | Binding | pKi | = | 8.4 | 8.4 | 3 | 2 | Guide to Pharmacology | None | None | None | None | 19199479 | |||||
| 3896 | 2443 | None | 0 | Mouse | Binding | pKi | = | 8.4 | 8.4 | -35 | 7 | Guide to Pharmacology | None | None | None | None | 9271210 | |||||
| 3896 | 2443 | None | 0 | Mouse | Binding | pKi | = | 8.4 | 8.4 | -35 | 7 | Guide to Pharmacology | None | None | None | None | 9832122 | |||||
| 6105 | 1744 | None | 0 | Human | Binding | pKi | = | 8.5 | 8.5 | 14 | 2 | Guide to Pharmacology | None | None | None | None | 19053761 | |||||
| 16132180 | 1724 | None | 20 | Rat | Binding | pKi | = | 8.5 | 8.5 | -1 | 8 | Guide to Pharmacology | None | None | None | None | 8562318 | |||||
| 16132180 | 1724 | None | 20 | Rat | Binding | pKi | = | 8.5 | 8.5 | -1 | 8 | Guide to Pharmacology | None | None | None | None | 8750821 | |||||
| 16132180 | 1724 | None | 20 | Rat | Binding | pKi | = | 8.5 | 8.5 | -1 | 8 | Guide to Pharmacology | None | None | None | None | 9281594 | |||||
| 16132180 | 1724 | None | 20 | Rat | Binding | pKi | = | 8.5 | 8.5 | -1 | 8 | Guide to Pharmacology | None | None | None | None | 9305929 | |||||
| 16132180 | 1724 | None | 20 | Rat | Binding | pKi | = | 8.5 | 8.5 | -1 | 8 | Guide to Pharmacology | None | None | None | None | 9405385 | |||||
| 16132180 | 1724 | None | 20 | Rat | Binding | pKi | = | 8.5 | 8.5 | -1 | 8 | Guide to Pharmacology | None | None | None | None | 9722565 | |||||
| 16132180 | 1724 | None | 20 | Rat | Binding | pKi | = | 8.5 | 8.5 | -1 | 8 | Guide to Pharmacology | None | None | None | None | 9742938 | |||||
| 16133822 | 1724 | None | 20 | Rat | Binding | pKi | = | 8.5 | 8.5 | -1 | 8 | Guide to Pharmacology | None | None | None | None | 8562318 | |||||
| 16133822 | 1724 | None | 20 | Rat | Binding | pKi | = | 8.5 | 8.5 | -1 | 8 | Guide to Pharmacology | None | None | None | None | 8750821 | |||||
| 16133822 | 1724 | None | 20 | Rat | Binding | pKi | = | 8.5 | 8.5 | -1 | 8 | Guide to Pharmacology | None | None | None | None | 9281594 | |||||
| 16133822 | 1724 | None | 20 | Rat | Binding | pKi | = | 8.5 | 8.5 | -1 | 8 | Guide to Pharmacology | None | None | None | None | 9305929 | |||||
| 16133822 | 1724 | None | 20 | Rat | Binding | pKi | = | 8.5 | 8.5 | -1 | 8 | Guide to Pharmacology | None | None | None | None | 9405385 | |||||
| 16133822 | 1724 | None | 20 | Rat | Binding | pKi | = | 8.5 | 8.5 | -1 | 8 | Guide to Pharmacology | None | None | None | None | 9722565 | |||||
| 16133822 | 1724 | None | 20 | Rat | Binding | pKi | = | 8.5 | 8.5 | -1 | 8 | Guide to Pharmacology | None | None | None | None | 9742938 | |||||
| 6087 | 1724 | None | 20 | Rat | Binding | pKi | = | 8.5 | 8.5 | -1 | 8 | Guide to Pharmacology | None | None | None | None | 8562318 | |||||
| 6087 | 1724 | None | 20 | Rat | Binding | pKi | = | 8.5 | 8.5 | -1 | 8 | Guide to Pharmacology | None | None | None | None | 8750821 | |||||
| 6087 | 1724 | None | 20 | Rat | Binding | pKi | = | 8.5 | 8.5 | -1 | 8 | Guide to Pharmacology | None | None | None | None | 9281594 | |||||
| 6087 | 1724 | None | 20 | Rat | Binding | pKi | = | 8.5 | 8.5 | -1 | 8 | Guide to Pharmacology | None | None | None | None | 9305929 | |||||
| 6087 | 1724 | None | 20 | Rat | Binding | pKi | = | 8.5 | 8.5 | -1 | 8 | Guide to Pharmacology | None | None | None | None | 9405385 | |||||
| 6087 | 1724 | None | 20 | Rat | Binding | pKi | = | 8.5 | 8.5 | -1 | 8 | Guide to Pharmacology | None | None | None | None | 9722565 | |||||
| 6087 | 1724 | None | 20 | Rat | Binding | pKi | = | 8.5 | 8.5 | -1 | 8 | Guide to Pharmacology | None | None | None | None | 9742938 | |||||
| CHEMBL499980 | 1724 | None | 20 | Rat | Binding | pKi | = | 8.5 | 8.5 | -1 | 8 | Guide to Pharmacology | None | None | None | None | 8562318 | |||||
| CHEMBL499980 | 1724 | None | 20 | Rat | Binding | pKi | = | 8.5 | 8.5 | -1 | 8 | Guide to Pharmacology | None | None | None | None | 8750821 | |||||
| CHEMBL499980 | 1724 | None | 20 | Rat | Binding | pKi | = | 8.5 | 8.5 | -1 | 8 | Guide to Pharmacology | None | None | None | None | 9281594 | |||||
| CHEMBL499980 | 1724 | None | 20 | Rat | Binding | pKi | = | 8.5 | 8.5 | -1 | 8 | Guide to Pharmacology | None | None | None | None | 9305929 | |||||
| CHEMBL499980 | 1724 | None | 20 | Rat | Binding | pKi | = | 8.5 | 8.5 | -1 | 8 | Guide to Pharmacology | None | None | None | None | 9405385 | |||||
| CHEMBL499980 | 1724 | None | 20 | Rat | Binding | pKi | = | 8.5 | 8.5 | -1 | 8 | Guide to Pharmacology | None | None | None | None | 9722565 | |||||
| CHEMBL499980 | 1724 | None | 20 | Rat | Binding | pKi | = | 8.5 | 8.5 | -1 | 8 | Guide to Pharmacology | None | None | None | None | 9742938 | |||||
| 3896 | 2443 | None | 0 | Rat | Binding | pKi | = | 8.6 | 8.6 | -24 | 7 | Guide to Pharmacology | None | None | None | None | 8750821 | |||||
| 3896 | 2443 | None | 0 | Rat | Binding | pKi | = | 8.6 | 8.6 | -24 | 7 | Guide to Pharmacology | None | None | None | None | 9281594 | |||||
| 3896 | 2443 | None | 0 | Rat | Binding | pKi | = | 8.6 | 8.6 | -24 | 7 | Guide to Pharmacology | None | None | None | None | 9305929 | |||||
| 3896 | 2443 | None | 0 | Rat | Binding | pKi | = | 8.6 | 8.6 | -24 | 7 | Guide to Pharmacology | None | None | None | None | 9722565 | |||||
| 6114 | 1747 | None | 0 | Human | Binding | pKi | = | 8.6 | 8.6 | 7 | 2 | Guide to Pharmacology | None | None | None | None | 19199479 | |||||
| 155817463 | 777 | None | 0 | Rat | Binding | pKi | = | 8.7 | 8.7 | -8 | 8 | Guide to Pharmacology | None | None | None | None | 8750821 | |||||
| 155817463 | 777 | None | 0 | Rat | Binding | pKi | = | 8.7 | 8.7 | -8 | 8 | Guide to Pharmacology | None | None | None | None | 9305929 | |||||
| 155817463 | 777 | None | 0 | Rat | Binding | pKi | = | 8.7 | 8.7 | -8 | 8 | Guide to Pharmacology | None | None | None | None | 9722565 | |||||
| 3861 | 777 | None | 0 | Rat | Binding | pKi | = | 8.7 | 8.7 | -8 | 8 | Guide to Pharmacology | None | None | None | None | 8750821 | |||||
| 3861 | 777 | None | 0 | Rat | Binding | pKi | = | 8.7 | 8.7 | -8 | 8 | Guide to Pharmacology | None | None | None | None | 9305929 | |||||
| 3861 | 777 | None | 0 | Rat | Binding | pKi | = | 8.7 | 8.7 | -8 | 8 | Guide to Pharmacology | None | None | None | None | 9722565 | |||||
| 16132180 | 1724 | None | 20 | Human | Binding | pKi | = | 8.8 | 8.8 | -1 | 8 | Guide to Pharmacology | None | None | None | None | 19053761 | |||||
| 16132180 | 1724 | None | 20 | Human | Binding | pKi | = | 8.8 | 8.8 | -1 | 8 | Guide to Pharmacology | None | None | None | None | 7524088 | |||||
| 16132180 | 1724 | None | 20 | Human | Binding | pKi | = | 8.8 | 8.8 | -1 | 8 | Guide to Pharmacology | None | None | None | None | 9808667 | |||||
| 16132180 | 1724 | None | 20 | Human | Binding | pKi | = | 8.8 | 8.8 | -1 | 8 | Guide to Pharmacology | None | None | None | None | 9880084 | |||||
| 16133822 | 1724 | None | 20 | Human | Binding | pKi | = | 8.8 | 8.8 | -1 | 8 | Guide to Pharmacology | None | None | None | None | 19053761 | |||||
| 16133822 | 1724 | None | 20 | Human | Binding | pKi | = | 8.8 | 8.8 | -1 | 8 | Guide to Pharmacology | None | None | None | None | 7524088 | |||||
| 16133822 | 1724 | None | 20 | Human | Binding | pKi | = | 8.8 | 8.8 | -1 | 8 | Guide to Pharmacology | None | None | None | None | 9808667 | |||||
| 16133822 | 1724 | None | 20 | Human | Binding | pKi | = | 8.8 | 8.8 | -1 | 8 | Guide to Pharmacology | None | None | None | None | 9880084 | |||||
| 6087 | 1724 | None | 20 | Human | Binding | pKi | = | 8.8 | 8.8 | -1 | 8 | Guide to Pharmacology | None | None | None | None | 19053761 | |||||
| 6087 | 1724 | None | 20 | Human | Binding | pKi | = | 8.8 | 8.8 | -1 | 8 | Guide to Pharmacology | None | None | None | None | 7524088 | |||||
| 6087 | 1724 | None | 20 | Human | Binding | pKi | = | 8.8 | 8.8 | -1 | 8 | Guide to Pharmacology | None | None | None | None | 9808667 | |||||
| 6087 | 1724 | None | 20 | Human | Binding | pKi | = | 8.8 | 8.8 | -1 | 8 | Guide to Pharmacology | None | None | None | None | 9880084 | |||||
| CHEMBL499980 | 1724 | None | 20 | Human | Binding | pKi | = | 8.8 | 8.8 | -1 | 8 | Guide to Pharmacology | None | None | None | None | 19053761 | |||||
| CHEMBL499980 | 1724 | None | 20 | Human | Binding | pKi | = | 8.8 | 8.8 | -1 | 8 | Guide to Pharmacology | None | None | None | None | 7524088 | |||||
| CHEMBL499980 | 1724 | None | 20 | Human | Binding | pKi | = | 8.8 | 8.8 | -1 | 8 | Guide to Pharmacology | None | None | None | None | 9808667 | |||||
| CHEMBL499980 | 1724 | None | 20 | Human | Binding | pKi | = | 8.8 | 8.8 | -1 | 8 | Guide to Pharmacology | None | None | None | None | 9880084 | |||||
| 16132180 | 1724 | None | 20 | Mouse | Binding | pKi | = | 8.8 | 8.8 | 1 | 8 | Guide to Pharmacology | None | None | None | None | 9271210 | |||||
| 16132180 | 1724 | None | 20 | Mouse | Binding | pKi | = | 8.8 | 8.8 | 1 | 8 | Guide to Pharmacology | None | None | None | None | 9832122 | |||||
| 16133822 | 1724 | None | 20 | Mouse | Binding | pKi | = | 8.8 | 8.8 | 1 | 8 | Guide to Pharmacology | None | None | None | None | 9271210 | |||||
| 16133822 | 1724 | None | 20 | Mouse | Binding | pKi | = | 8.8 | 8.8 | 1 | 8 | Guide to Pharmacology | None | None | None | None | 9832122 | |||||
| 6087 | 1724 | None | 20 | Mouse | Binding | pKi | = | 8.8 | 8.8 | 1 | 8 | Guide to Pharmacology | None | None | None | None | 9271210 | |||||
| 6087 | 1724 | None | 20 | Mouse | Binding | pKi | = | 8.8 | 8.8 | 1 | 8 | Guide to Pharmacology | None | None | None | None | 9832122 | |||||
| CHEMBL499980 | 1724 | None | 20 | Mouse | Binding | pKi | = | 8.8 | 8.8 | 1 | 8 | Guide to Pharmacology | None | None | None | None | 9271210 | |||||
| CHEMBL499980 | 1724 | None | 20 | Mouse | Binding | pKi | = | 8.8 | 8.8 | 1 | 8 | Guide to Pharmacology | None | None | None | None | 9832122 | |||||
| 6113 | 1746 | None | 0 | Human | Binding | pKi | = | 8.9 | 8.9 | 11 | 2 | Guide to Pharmacology | None | None | None | None | 19199479 | |||||
| 155817463 | 777 | None | 0 | Mouse | Binding | pKi | = | 8.9 | 8.9 | -5 | 8 | Guide to Pharmacology | None | None | None | None | 9271210 | |||||
| 155817463 | 777 | None | 0 | Mouse | Binding | pKi | = | 8.9 | 8.9 | -5 | 8 | Guide to Pharmacology | None | None | None | None | 9832122 | |||||
| 3861 | 777 | None | 0 | Mouse | Binding | pKi | = | 8.9 | 8.9 | -5 | 8 | Guide to Pharmacology | None | None | None | None | 9271210 | |||||
| 3861 | 777 | None | 0 | Mouse | Binding | pKi | = | 8.9 | 8.9 | -5 | 8 | Guide to Pharmacology | None | None | None | None | 9832122 | |||||
| 6112 | 1745 | None | 0 | Human | Binding | pKi | = | 8.9 | 8.9 | 11 | 2 | Guide to Pharmacology | None | None | None | None | 19199479 | |||||
| 6106 | 1750 | None | 0 | Human | Binding | pKi | = | 8.9 | 8.9 | 10 | 2 | Guide to Pharmacology | None | None | None | None | 23259957 | |||||
| 6111 | 1749 | None | 0 | Human | Binding | pKi | = | 9.2 | 9.2 | 20 | 2 | Guide to Pharmacology | None | None | None | None | 19199479 | |||||
| 3897 | 2445 | None | 0 | Rat | Binding | pKi | = | 9.2 | 9.2 | -2 | 6 | Guide to Pharmacology | None | None | None | None | 9305929 | |||||
| 3897 | 2445 | None | 0 | Rat | Binding | pKi | = | 9.2 | 9.2 | -2 | 6 | Guide to Pharmacology | None | None | None | None | 9722565 | |||||
| 3899 | 2447 | None | 0 | Human | Binding | pKi | = | 9.3 | 9.3 | -3 | 8 | Guide to Pharmacology | None | None | None | None | 15944002 | |||||
| 3899 | 2447 | None | 0 | Human | Binding | pKi | = | 9.3 | 9.3 | -3 | 8 | Guide to Pharmacology | None | None | None | None | 9808667 | |||||
| 3899 | 2447 | None | 0 | Human | Binding | pKi | = | 9.3 | 9.3 | -3 | 8 | Guide to Pharmacology | None | None | None | None | 9880084 | |||||
| 6116 | 1751 | None | 0 | Human | Binding | pKi | = | 9.3 | 9.3 | 40 | 2 | Guide to Pharmacology | None | None | None | None | 19199479 | |||||
| 6110 | 1753 | None | 0 | Human | Binding | pKi | = | 9.4 | 9.4 | 60 | 2 | Guide to Pharmacology | None | None | None | None | 19199479 | |||||
| 16133243 | 1715 | None | 0 | Human | Binding | pKi | = | 9.4 | 9.4 | -2 | 8 | Guide to Pharmacology | None | None | None | None | 15944002 | |||||
| 16133243 | 1715 | None | 0 | Human | Binding | pKi | = | 9.4 | 9.4 | -2 | 8 | Guide to Pharmacology | None | None | None | None | 19467704 | |||||
| 16133243 | 1715 | None | 0 | Human | Binding | pKi | = | 9.4 | 9.4 | -2 | 8 | Guide to Pharmacology | None | None | None | None | 21333705 | |||||
| 16133243 | 1715 | None | 0 | Human | Binding | pKi | = | 9.4 | 9.4 | -2 | 8 | Guide to Pharmacology | None | None | None | None | 7524088 | |||||
| 16133243 | 1715 | None | 0 | Human | Binding | pKi | = | 9.4 | 9.4 | -2 | 8 | Guide to Pharmacology | None | None | None | None | 9880084 | |||||
| 3593 | 1715 | None | 0 | Human | Binding | pKi | = | 9.4 | 9.4 | -2 | 8 | Guide to Pharmacology | None | None | None | None | 15944002 | |||||
| 3593 | 1715 | None | 0 | Human | Binding | pKi | = | 9.4 | 9.4 | -2 | 8 | Guide to Pharmacology | None | None | None | None | 19467704 | |||||
| 3593 | 1715 | None | 0 | Human | Binding | pKi | = | 9.4 | 9.4 | -2 | 8 | Guide to Pharmacology | None | None | None | None | 21333705 | |||||
| 3593 | 1715 | None | 0 | Human | Binding | pKi | = | 9.4 | 9.4 | -2 | 8 | Guide to Pharmacology | None | None | None | None | 7524088 | |||||
| 3593 | 1715 | None | 0 | Human | Binding | pKi | = | 9.4 | 9.4 | -2 | 8 | Guide to Pharmacology | None | None | None | None | 9880084 | |||||
| 3898 | 2446 | None | 0 | Rat | Binding | pKi | = | 9.4 | 9.4 | -1 | 7 | Guide to Pharmacology | None | None | None | None | 8750821 | |||||
| 3898 | 2446 | None | 0 | Rat | Binding | pKi | = | 9.4 | 9.4 | -1 | 7 | Guide to Pharmacology | None | None | None | None | 9305929 | |||||
| 3898 | 2446 | None | 0 | Rat | Binding | pKi | = | 9.4 | 9.4 | -1 | 7 | Guide to Pharmacology | None | None | None | None | 9722565 | |||||
| 155817484 | 1714 | None | 0 | Rat | Binding | pKi | = | 9.5 | 9.5 | -1 | 6 | Guide to Pharmacology | None | None | None | None | 8562318 | |||||
| 155817484 | 1714 | None | 0 | Rat | Binding | pKi | = | 9.5 | 9.5 | -1 | 6 | Guide to Pharmacology | None | None | None | None | 8750821 | |||||
| 155817484 | 1714 | None | 0 | Rat | Binding | pKi | = | 9.5 | 9.5 | -1 | 6 | Guide to Pharmacology | None | None | None | None | 9305929 | |||||
| 155817484 | 1714 | None | 0 | Rat | Binding | pKi | = | 9.5 | 9.5 | -1 | 6 | Guide to Pharmacology | None | None | None | None | 9722565 | |||||
| 6117 | 1714 | None | 0 | Rat | Binding | pKi | = | 9.5 | 9.5 | -1 | 6 | Guide to Pharmacology | None | None | None | None | 8562318 | |||||
| 6117 | 1714 | None | 0 | Rat | Binding | pKi | = | 9.5 | 9.5 | -1 | 6 | Guide to Pharmacology | None | None | None | None | 8750821 | |||||
| 6117 | 1714 | None | 0 | Rat | Binding | pKi | = | 9.5 | 9.5 | -1 | 6 | Guide to Pharmacology | None | None | None | None | 9305929 | |||||
| 6117 | 1714 | None | 0 | Rat | Binding | pKi | = | 9.5 | 9.5 | -1 | 6 | Guide to Pharmacology | None | None | None | None | 9722565 | |||||
| 6129 | 1714 | None | 0 | Rat | Binding | pKi | = | 9.5 | 9.5 | -1 | 6 | Guide to Pharmacology | None | None | None | None | 8562318 | |||||
| 6129 | 1714 | None | 0 | Rat | Binding | pKi | = | 9.5 | 9.5 | -1 | 6 | Guide to Pharmacology | None | None | None | None | 8750821 | |||||
| 6129 | 1714 | None | 0 | Rat | Binding | pKi | = | 9.5 | 9.5 | -1 | 6 | Guide to Pharmacology | None | None | None | None | 9305929 | |||||
| 6129 | 1714 | None | 0 | Rat | Binding | pKi | = | 9.5 | 9.5 | -1 | 6 | Guide to Pharmacology | None | None | None | None | 9722565 | |||||
| 101927062 | 1716 | None | 20 | Rat | Binding | pKi | = | 9.5 | 9.5 | 8 | 6 | Guide to Pharmacology | None | None | None | None | 8562318 | |||||
| 101927062 | 1716 | None | 20 | Rat | Binding | pKi | = | 9.5 | 9.5 | 8 | 6 | Guide to Pharmacology | None | None | None | None | 9722565 | |||||
| 155817445 | 1716 | None | 20 | Rat | Binding | pKi | = | 9.5 | 9.5 | 8 | 6 | Guide to Pharmacology | None | None | None | None | 8562318 | |||||
| 155817445 | 1716 | None | 20 | Rat | Binding | pKi | = | 9.5 | 9.5 | 8 | 6 | Guide to Pharmacology | None | None | None | None | 9722565 | |||||
| 16133823 | 1716 | None | 20 | Rat | Binding | pKi | = | 9.5 | 9.5 | 8 | 6 | Guide to Pharmacology | None | None | None | None | 8562318 | |||||
| 16133823 | 1716 | None | 20 | Rat | Binding | pKi | = | 9.5 | 9.5 | 8 | 6 | Guide to Pharmacology | None | None | None | None | 9722565 | |||||
| 3592 | 1716 | None | 20 | Rat | Binding | pKi | = | 9.5 | 9.5 | 8 | 6 | Guide to Pharmacology | None | None | None | None | 8562318 | |||||
| 3592 | 1716 | None | 20 | Rat | Binding | pKi | = | 9.5 | 9.5 | 8 | 6 | Guide to Pharmacology | None | None | None | None | 9722565 | |||||
| 44584852 | 1716 | None | 20 | Rat | Binding | pKi | = | 9.5 | 9.5 | 8 | 6 | Guide to Pharmacology | None | None | None | None | 8562318 | |||||
| 44584852 | 1716 | None | 20 | Rat | Binding | pKi | = | 9.5 | 9.5 | 8 | 6 | Guide to Pharmacology | None | None | None | None | 9722565 | |||||
| 6090 | 1716 | None | 20 | Rat | Binding | pKi | = | 9.5 | 9.5 | 8 | 6 | Guide to Pharmacology | None | None | None | None | 8562318 | |||||
| 6090 | 1716 | None | 20 | Rat | Binding | pKi | = | 9.5 | 9.5 | 8 | 6 | Guide to Pharmacology | None | None | None | None | 9722565 | |||||
| 91898917 | 1716 | None | 20 | Rat | Binding | pKi | = | 9.5 | 9.5 | 8 | 6 | Guide to Pharmacology | None | None | None | None | 8562318 | |||||
| 91898917 | 1716 | None | 20 | Rat | Binding | pKi | = | 9.5 | 9.5 | 8 | 6 | Guide to Pharmacology | None | None | None | None | 9722565 | |||||
| CHEMBL506553 | 1716 | None | 20 | Rat | Binding | pKi | = | 9.5 | 9.5 | 8 | 6 | Guide to Pharmacology | None | None | None | None | 8562318 | |||||
| CHEMBL506553 | 1716 | None | 20 | Rat | Binding | pKi | = | 9.5 | 9.5 | 8 | 6 | Guide to Pharmacology | None | None | None | None | 9722565 | |||||
| 16133243 | 1715 | None | 0 | Rat | Binding | pKi | = | 9.6 | 9.6 | -1 | 8 | Guide to Pharmacology | None | None | None | None | 8562318 | |||||
| 16133243 | 1715 | None | 0 | Rat | Binding | pKi | = | 9.6 | 9.6 | -1 | 8 | Guide to Pharmacology | None | None | None | None | 9281594 | |||||
| 16133243 | 1715 | None | 0 | Rat | Binding | pKi | = | 9.6 | 9.6 | -1 | 8 | Guide to Pharmacology | None | None | None | None | 9405385 | |||||
| 16133243 | 1715 | None | 0 | Rat | Binding | pKi | = | 9.6 | 9.6 | -1 | 8 | Guide to Pharmacology | None | None | None | None | 9722565 | |||||
| 16133243 | 1715 | None | 0 | Rat | Binding | pKi | = | 9.6 | 9.6 | -1 | 8 | Guide to Pharmacology | None | None | None | None | 9742938 | |||||
| 3593 | 1715 | None | 0 | Rat | Binding | pKi | = | 9.6 | 9.6 | -1 | 8 | Guide to Pharmacology | None | None | None | None | 8562318 | |||||
| 3593 | 1715 | None | 0 | Rat | Binding | pKi | = | 9.6 | 9.6 | -1 | 8 | Guide to Pharmacology | None | None | None | None | 9281594 | |||||
| 3593 | 1715 | None | 0 | Rat | Binding | pKi | = | 9.6 | 9.6 | -1 | 8 | Guide to Pharmacology | None | None | None | None | 9405385 | |||||
| 3593 | 1715 | None | 0 | Rat | Binding | pKi | = | 9.6 | 9.6 | -1 | 8 | Guide to Pharmacology | None | None | None | None | 9722565 | |||||
| 3593 | 1715 | None | 0 | Rat | Binding | pKi | = | 9.6 | 9.6 | -1 | 8 | Guide to Pharmacology | None | None | None | None | 9742938 | |||||
| 6099 | 2444 | None | 0 | Human | Binding | pKi | = | 9.6 | 9.6 | 23 | 2 | Guide to Pharmacology | None | None | None | None | 11600206 | |||||
| 3898 | 2446 | None | 0 | Human | Binding | pKi | = | 9.6 | 9.6 | 1 | 7 | Guide to Pharmacology | None | None | None | None | 15944002 | |||||
| 3898 | 2446 | None | 0 | Human | Binding | pKi | = | 9.6 | 9.6 | 1 | 7 | Guide to Pharmacology | None | None | None | None | 9808667 | |||||
| 3898 | 2446 | None | 0 | Human | Binding | pKi | = | 9.6 | 9.6 | 1 | 7 | Guide to Pharmacology | None | None | None | None | 9880084 | |||||
| 155817463 | 777 | None | 0 | Human | Binding | pKi | = | 9.6 | 9.6 | 4 | 8 | Guide to Pharmacology | None | None | None | None | 9808667 | |||||
| 155817463 | 777 | None | 0 | Human | Binding | pKi | = | 9.6 | 9.6 | 4 | 8 | Guide to Pharmacology | None | None | None | None | 9880084 | |||||
| 3861 | 777 | None | 0 | Human | Binding | pKi | = | 9.6 | 9.6 | 4 | 8 | Guide to Pharmacology | None | None | None | None | 9808667 | |||||
| 3861 | 777 | None | 0 | Human | Binding | pKi | = | 9.6 | 9.6 | 4 | 8 | Guide to Pharmacology | None | None | None | None | 9880084 | |||||
| 6100 | 2449 | None | 0 | Human | Binding | pKi | = | 9.6 | 9.6 | 25 | 3 | Guide to Pharmacology | None | None | None | None | None | |||||
| 3897 | 2445 | None | 0 | Human | Binding | pKi | = | 9.7 | 9.7 | 2 | 6 | Guide to Pharmacology | None | None | None | None | 11600206 | |||||
| 3897 | 2445 | None | 0 | Human | Binding | pKi | = | 9.7 | 9.7 | 2 | 6 | Guide to Pharmacology | None | None | None | None | 9880084 | |||||
| 101927062 | 1716 | None | 20 | Human | Binding | pKi | = | 9.8 | 9.8 | -10 | 6 | Guide to Pharmacology | None | None | None | None | 11600206 | |||||
| 101927062 | 1716 | None | 20 | Human | Binding | pKi | = | 9.8 | 9.8 | -10 | 6 | Guide to Pharmacology | None | None | None | None | 7524088 | |||||
| 101927062 | 1716 | None | 20 | Human | Binding | pKi | = | 9.8 | 9.8 | -10 | 6 | Guide to Pharmacology | None | None | None | None | 9808667 | |||||
| 101927062 | 1716 | None | 20 | Human | Binding | pKi | = | 9.8 | 9.8 | -10 | 6 | Guide to Pharmacology | None | None | None | None | 9880084 | |||||
| 155817445 | 1716 | None | 20 | Human | Binding | pKi | = | 9.8 | 9.8 | -10 | 6 | Guide to Pharmacology | None | None | None | None | 11600206 | |||||
| 155817445 | 1716 | None | 20 | Human | Binding | pKi | = | 9.8 | 9.8 | -10 | 6 | Guide to Pharmacology | None | None | None | None | 7524088 | |||||
| 155817445 | 1716 | None | 20 | Human | Binding | pKi | = | 9.8 | 9.8 | -10 | 6 | Guide to Pharmacology | None | None | None | None | 9808667 | |||||
| 155817445 | 1716 | None | 20 | Human | Binding | pKi | = | 9.8 | 9.8 | -10 | 6 | Guide to Pharmacology | None | None | None | None | 9880084 | |||||
| 16133823 | 1716 | None | 20 | Human | Binding | pKi | = | 9.8 | 9.8 | -10 | 6 | Guide to Pharmacology | None | None | None | None | 11600206 | |||||
| 16133823 | 1716 | None | 20 | Human | Binding | pKi | = | 9.8 | 9.8 | -10 | 6 | Guide to Pharmacology | None | None | None | None | 7524088 | |||||
| 16133823 | 1716 | None | 20 | Human | Binding | pKi | = | 9.8 | 9.8 | -10 | 6 | Guide to Pharmacology | None | None | None | None | 9808667 | |||||
| 16133823 | 1716 | None | 20 | Human | Binding | pKi | = | 9.8 | 9.8 | -10 | 6 | Guide to Pharmacology | None | None | None | None | 9880084 | |||||
| 3592 | 1716 | None | 20 | Human | Binding | pKi | = | 9.8 | 9.8 | -10 | 6 | Guide to Pharmacology | None | None | None | None | 11600206 | |||||
| 3592 | 1716 | None | 20 | Human | Binding | pKi | = | 9.8 | 9.8 | -10 | 6 | Guide to Pharmacology | None | None | None | None | 7524088 | |||||
| 3592 | 1716 | None | 20 | Human | Binding | pKi | = | 9.8 | 9.8 | -10 | 6 | Guide to Pharmacology | None | None | None | None | 9808667 | |||||
| 3592 | 1716 | None | 20 | Human | Binding | pKi | = | 9.8 | 9.8 | -10 | 6 | Guide to Pharmacology | None | None | None | None | 9880084 | |||||
| 44584852 | 1716 | None | 20 | Human | Binding | pKi | = | 9.8 | 9.8 | -10 | 6 | Guide to Pharmacology | None | None | None | None | 11600206 | |||||
| 44584852 | 1716 | None | 20 | Human | Binding | pKi | = | 9.8 | 9.8 | -10 | 6 | Guide to Pharmacology | None | None | None | None | 7524088 | |||||
| 44584852 | 1716 | None | 20 | Human | Binding | pKi | = | 9.8 | 9.8 | -10 | 6 | Guide to Pharmacology | None | None | None | None | 9808667 | |||||
| 44584852 | 1716 | None | 20 | Human | Binding | pKi | = | 9.8 | 9.8 | -10 | 6 | Guide to Pharmacology | None | None | None | None | 9880084 | |||||
| 6090 | 1716 | None | 20 | Human | Binding | pKi | = | 9.8 | 9.8 | -10 | 6 | Guide to Pharmacology | None | None | None | None | 11600206 | |||||
| 6090 | 1716 | None | 20 | Human | Binding | pKi | = | 9.8 | 9.8 | -10 | 6 | Guide to Pharmacology | None | None | None | None | 7524088 | |||||
| 6090 | 1716 | None | 20 | Human | Binding | pKi | = | 9.8 | 9.8 | -10 | 6 | Guide to Pharmacology | None | None | None | None | 9808667 | |||||
| 6090 | 1716 | None | 20 | Human | Binding | pKi | = | 9.8 | 9.8 | -10 | 6 | Guide to Pharmacology | None | None | None | None | 9880084 | |||||
| 91898917 | 1716 | None | 20 | Human | Binding | pKi | = | 9.8 | 9.8 | -10 | 6 | Guide to Pharmacology | None | None | None | None | 11600206 | |||||
| 91898917 | 1716 | None | 20 | Human | Binding | pKi | = | 9.8 | 9.8 | -10 | 6 | Guide to Pharmacology | None | None | None | None | 7524088 | |||||
| 91898917 | 1716 | None | 20 | Human | Binding | pKi | = | 9.8 | 9.8 | -10 | 6 | Guide to Pharmacology | None | None | None | None | 9808667 | |||||
| 91898917 | 1716 | None | 20 | Human | Binding | pKi | = | 9.8 | 9.8 | -10 | 6 | Guide to Pharmacology | None | None | None | None | 9880084 | |||||
| CHEMBL506553 | 1716 | None | 20 | Human | Binding | pKi | = | 9.8 | 9.8 | -10 | 6 | Guide to Pharmacology | None | None | None | None | 11600206 | |||||
| CHEMBL506553 | 1716 | None | 20 | Human | Binding | pKi | = | 9.8 | 9.8 | -10 | 6 | Guide to Pharmacology | None | None | None | None | 7524088 | |||||
| CHEMBL506553 | 1716 | None | 20 | Human | Binding | pKi | = | 9.8 | 9.8 | -10 | 6 | Guide to Pharmacology | None | None | None | None | 9808667 | |||||
| CHEMBL506553 | 1716 | None | 20 | Human | Binding | pKi | = | 9.8 | 9.8 | -10 | 6 | Guide to Pharmacology | None | None | None | None | 9880084 | |||||
| 16133243 | 1715 | None | 0 | Mouse | Binding | pKi | = | 9.8 | 9.8 | 1 | 8 | Guide to Pharmacology | None | None | None | None | 9271210 | |||||
| 16133243 | 1715 | None | 0 | Mouse | Binding | pKi | = | 9.8 | 9.8 | 1 | 8 | Guide to Pharmacology | None | None | None | None | 9832122 | |||||
| 3593 | 1715 | None | 0 | Mouse | Binding | pKi | = | 9.8 | 9.8 | 1 | 8 | Guide to Pharmacology | None | None | None | None | 9271210 | |||||
| 3593 | 1715 | None | 0 | Mouse | Binding | pKi | = | 9.8 | 9.8 | 1 | 8 | Guide to Pharmacology | None | None | None | None | 9832122 | |||||
| 3899 | 2447 | None | 0 | Mouse | Binding | pKi | = | 9.9 | 9.9 | 3 | 8 | Guide to Pharmacology | None | None | None | None | 9271210 | |||||
| 3899 | 2447 | None | 0 | Mouse | Binding | pKi | = | 9.9 | 9.9 | 3 | 8 | Guide to Pharmacology | None | None | None | None | 9832122 | |||||
| 3896 | 2443 | None | 0 | Human | Binding | pKi | = | 10.0 | 10.0 | 13 | 7 | Guide to Pharmacology | None | None | None | None | 15944002 | |||||
| 3896 | 2443 | None | 0 | Human | Binding | pKi | = | 10.0 | 10.0 | 13 | 7 | Guide to Pharmacology | None | None | None | None | 9808667 | |||||
| 3896 | 2443 | None | 0 | Human | Binding | pKi | = | 10.0 | 10.0 | 13 | 7 | Guide to Pharmacology | None | None | None | None | 9880084 | |||||
| 6127 | 1761 | None | 0 | Human | Binding | pKi | > | 5 | 5.0 | -575 | 3 | Guide to Pharmacology | 397 | 3 | 0 | 4 | 5.2 | COc1ccc(cn1)N1C(=O)/C(=N/c2ccc(c(c2)Cl)Cl)/c2c1cccc2 | 15944007 | |||
| 9800980 | 1761 | None | 0 | Human | Binding | pKi | > | 5 | 5.0 | -575 | 3 | Guide to Pharmacology | 397 | 3 | 0 | 4 | 5.2 | COc1ccc(cn1)N1C(=O)/C(=N/c2ccc(c(c2)Cl)Cl)/c2c1cccc2 | 15944007 | |||
| 155817474 | 1728 | None | 0 | Human | Binding | pKi | > | 5.3 | 5.3 | -301 | 5 | Guide to Pharmacology | None | None | None | None | 15944002 | |||||
| 5357 | 1728 | None | 0 | Human | Binding | pKi | > | 5.3 | 5.3 | -301 | 5 | Guide to Pharmacology | None | None | None | None | 15944002 | |||||
| 155817480 | 1731 | None | 0 | Human | Binding | pKi | > | 5.5 | 5.5 | -3 | 6 | Guide to Pharmacology | None | None | None | None | 7524088 | |||||
| 155817480 | 1731 | None | 0 | Human | Binding | pKi | > | 5.5 | 5.5 | -3 | 6 | Guide to Pharmacology | None | None | None | None | 9880084 | |||||
| 6091 | 1731 | None | 0 | Human | Binding | pKi | > | 5.5 | 5.5 | -3 | 6 | Guide to Pharmacology | None | None | None | None | 7524088 | |||||
| 6091 | 1731 | None | 0 | Human | Binding | pKi | > | 5.5 | 5.5 | -3 | 6 | Guide to Pharmacology | None | None | None | None | 9880084 | |||||
| 155817482 | 1718 | None | 0 | Mouse | Binding | pKi | > | 5.8 | 5.8 | -2 | 3 | Guide to Pharmacology | None | None | None | None | 9832122 | |||||
| 6093 | 1718 | None | 0 | Mouse | Binding | pKi | > | 5.8 | 5.8 | -2 | 3 | Guide to Pharmacology | None | None | None | None | 9832122 | |||||
| 155817481 | 1732 | None | 0 | Mouse | Binding | pKi | > | 5.8 | 5.8 | -2 | 6 | Guide to Pharmacology | None | None | None | None | 9832122 | |||||
| 6092 | 1732 | None | 0 | Mouse | Binding | pKi | > | 5.8 | 5.8 | -2 | 6 | Guide to Pharmacology | None | None | None | None | 9832122 | |||||
| 155817483 | 1717 | None | 0 | Rat | Binding | pKi | > | 6 | 6.0 | -1 | 2 | Guide to Pharmacology | None | None | None | None | 8750821 | |||||
| 6094 | 1717 | None | 0 | Rat | Binding | pKi | > | 6 | 6.0 | -1 | 2 | Guide to Pharmacology | None | None | None | None | 8750821 | |||||
| 155817480 | 1731 | None | 0 | Rat | Binding | pKi | > | 6 | 6.0 | -1 | 6 | Guide to Pharmacology | None | None | None | None | 8562318 | |||||
| 155817480 | 1731 | None | 0 | Rat | Binding | pKi | > | 6 | 6.0 | -1 | 6 | Guide to Pharmacology | None | None | None | None | 8750821 | |||||
| 155817480 | 1731 | None | 0 | Rat | Binding | pKi | > | 6 | 6.0 | -1 | 6 | Guide to Pharmacology | None | None | None | None | 9305929 | |||||
| 155817480 | 1731 | None | 0 | Rat | Binding | pKi | > | 6 | 6.0 | -1 | 6 | Guide to Pharmacology | None | None | None | None | 9722565 | |||||
| 6091 | 1731 | None | 0 | Rat | Binding | pKi | > | 6 | 6.0 | -1 | 6 | Guide to Pharmacology | None | None | None | None | 8562318 | |||||
| 6091 | 1731 | None | 0 | Rat | Binding | pKi | > | 6 | 6.0 | -1 | 6 | Guide to Pharmacology | None | None | None | None | 8750821 | |||||
| 6091 | 1731 | None | 0 | Rat | Binding | pKi | > | 6 | 6.0 | -1 | 6 | Guide to Pharmacology | None | None | None | None | 9305929 | |||||
| 6091 | 1731 | None | 0 | Rat | Binding | pKi | > | 6 | 6.0 | -1 | 6 | Guide to Pharmacology | None | None | None | None | 9722565 | |||||
| 155817481 | 1732 | None | 0 | Rat | Binding | pKi | > | 6 | 6.0 | -1 | 6 | Guide to Pharmacology | None | None | None | None | 9405385 | |||||
| 155817481 | 1732 | None | 0 | Rat | Binding | pKi | > | 6 | 6.0 | -1 | 6 | Guide to Pharmacology | None | None | None | None | 9742938 | |||||
| 6092 | 1732 | None | 0 | Rat | Binding | pKi | > | 6 | 6.0 | -1 | 6 | Guide to Pharmacology | None | None | None | None | 9405385 | |||||
| 6092 | 1732 | None | 0 | Rat | Binding | pKi | > | 6 | 6.0 | -1 | 6 | Guide to Pharmacology | None | None | None | None | 9742938 | |||||