Refined structure (7XTC) of Gs - 5-HT7 receptor

GPCR CLASS (FAMILY)

A (Rhodopsin)

SPECIES

Homo sapiens

G PROTEIN FAMILY

Gs

DATE

2024-02-01

3D VIEW

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Structure
GPCR
Gα
Gβ
Gγ
Model
AlphaFold2-Multimer

REFINED G PROTEIN RESIDUES

Residue backbones - 240 from structure (60.9%), 154 from model (39.1%)
Residue sidechains - 232 from structure (58.9%), 162 from model (41.1%)
Segment Seq.num. AA CGN# Backbone from Sidechain from
G.HN 1 M G.HN.01 AF2 AF2
G.HN 2 G G.HN.02 AF2 AF2
G.HN 3 C G.HN.09 AF2 AF2
G.HN 4 L G.HN.10 AF2 AF2
G.HN 5 G G.HN.11 AF2 AF2
G.HN 6 N G.HN.22 AF2 AF2
G.HN 7 S G.HN.23 AF2 AF2
G.HN 8 K G.HN.24 AF2 AF2
G.HN 9 T G.HN.26 Structure Structure
G.HN 10 E G.HN.27 Structure Structure
G.HN 11 D G.HN.28 Structure Structure
G.HN 12 Q G.HN.29 Structure Structure
G.HN 13 R G.HN.30 Structure Structure
G.HN 14 N G.HN.31 Structure Structure
G.HN 15 E G.HN.32 Structure Structure
G.HN 16 E G.HN.33 Structure Structure
G.HN 17 K G.HN.34 Structure Structure
G.HN 18 A G.HN.35 Structure Structure
G.HN 19 Q G.HN.36 Structure Structure
G.HN 20 R G.HN.37 Structure Structure
G.HN 21 E G.HN.38 Structure Structure
G.HN 22 A G.HN.39 Structure Structure
G.HN 23 N G.HN.40 Structure Structure
G.HN 24 K G.HN.41 Structure Structure
G.HN 25 K G.HN.42 Structure Structure
G.HN 26 I G.HN.43 Structure Structure
G.HN 27 E G.HN.44 Structure Structure
G.HN 28 K G.HN.45 Structure Structure
G.HN 29 Q G.HN.46 Structure Structure
G.HN 30 L G.HN.47 Structure Structure
G.HN 31 Q G.HN.48 Structure Structure
G.HN 32 K G.HN.49 Structure Structure
G.HN 33 D G.HN.50 Structure Structure
G.HN 34 K G.HN.51 Structure Structure
G.HN 35 Q G.HN.52 Structure Structure
G.HN 36 V G.HN.53 Structure Structure
G.hns1 37 Y G.hns1.01 Structure Structure
G.hns1 38 R G.hns1.02 Structure Structure
G.hns1 39 A G.hns1.03 Structure Structure
G.S1 40 T G.S1.01 Structure Structure
G.S1 41 H G.S1.02 Structure Structure
G.S1 42 R G.S1.03 Structure Structure
G.S1 43 L G.S1.04 Structure Structure
G.S1 44 L G.S1.05 Structure Structure
G.S1 45 L G.S1.06 Structure Structure
G.S1 46 L G.S1.07 Structure Structure
G.s1h1 47 G G.s1h1.01 Structure Structure
G.s1h1 48 A G.s1h1.02 Structure Structure
G.s1h1 49 G G.s1h1.03 Structure Structure
G.s1h1 50 E G.s1h1.04 Structure Structure
G.s1h1 51 S G.s1h1.05 Structure Structure
G.s1h1 52 G G.s1h1.06 Structure Structure
G.H1 53 K G.H1.01 Structure Structure
G.H1 54 S G.H1.02 Structure AF2
G.H1 55 T G.H1.03 Structure Structure
G.H1 56 I G.H1.04 Structure Structure
G.H1 57 V G.H1.05 Structure Structure
G.H1 58 K G.H1.06 Structure Structure
G.H1 59 Q G.H1.07 Structure Structure
G.H1 60 M G.H1.08 Structure Structure
G.H1 61 R G.H1.09 Structure Structure
G.H1 62 I G.H1.10 Structure Structure
G.H1 63 L G.H1.11 AF2 AF2
G.H1 64 H G.H1.12 AF2 AF2
G.h1ha 65 V G.h1ha.01 AF2 AF2
G.h1ha 66 N G.h1ha.02 AF2 AF2
G.h1ha 67 G G.h1ha.03 AF2 AF2
G.h1ha 68 F G.h1ha.04 AF2 AF2
G.h1ha 69 N G.h1ha.05 AF2 AF2
G.h1ha 70 G G.h1ha.06 AF2 AF2
G.h1ha 71 E G.h1ha.07 AF2 AF2
G.h1ha 72 G G.h1ha.08 AF2 AF2
G.h1ha 73 G G.h1ha.09 AF2 AF2
G.h1ha 74 E G.h1ha.10 AF2 AF2
G.h1ha 75 E G.h1ha.11 AF2 AF2
G.h1ha 76 D G.h1ha.12 AF2 AF2
G.h1ha 77 P G.h1ha.13 AF2 AF2
G.h1ha 78 Q G.h1ha.14 AF2 AF2
G.h1ha 79 A G.h1ha.15 AF2 AF2
G.h1ha 80 A G.h1ha.16 AF2 AF2
G.h1ha 81 R G.h1ha.17 AF2 AF2
G.h1ha 82 S G.h1ha.18 AF2 AF2
G.h1ha 83 N G.h1ha.19 AF2 AF2
G.h1ha 84 S G.h1ha.20 AF2 AF2
H.HA 85 D H.HA.01 AF2 AF2
H.HA 86 G H.HA.02 AF2 AF2
H.HA 87 E H.HA.03 AF2 AF2
H.HA 88 K H.HA.04 AF2 AF2
H.HA 89 A H.HA.05 AF2 AF2
H.HA 90 T H.HA.06 AF2 AF2
H.HA 91 K H.HA.07 AF2 AF2
H.HA 92 V H.HA.08 AF2 AF2
H.HA 93 Q H.HA.09 AF2 AF2
H.HA 94 D H.HA.10 AF2 AF2
H.HA 95 I H.HA.11 AF2 AF2
H.HA 96 K H.HA.12 AF2 AF2
H.HA 97 N H.HA.13 AF2 AF2
H.HA 98 N H.HA.14 AF2 AF2
H.HA 99 L H.HA.15 AF2 AF2
H.HA 100 K H.HA.16 AF2 AF2
H.HA 101 E H.HA.17 AF2 AF2
H.HA 102 A H.HA.18 AF2 AF2
H.HA 103 I H.HA.19 AF2 AF2
H.HA 104 E H.HA.20 AF2 AF2
H.HA 105 T H.HA.21 AF2 AF2
H.HA 106 I H.HA.22 AF2 AF2
H.HA 107 V H.HA.23 AF2 AF2
H.HA 108 A H.HA.24 AF2 AF2
H.HA 109 A H.HA.25 AF2 AF2
H.HA 110 M H.HA.26 AF2 AF2
H.HA 111 S H.HA.27 AF2 AF2
H.HA 112 N H.HA.28 AF2 AF2
H.HA 113 L H.HA.29 AF2 AF2
H.hahb 114 V H.hahb.01 AF2 AF2
H.hahb 115 P H.hahb.02 AF2 AF2
H.hahb 116 P H.hahb.03 AF2 AF2
H.hahb 117 V H.hahb.04 AF2 AF2
H.hahb 118 E H.hahb.05 AF2 AF2
H.hahb 119 L H.hahb.06 AF2 AF2
H.hahb 120 A H.hahb.07 AF2 AF2
H.hahb 121 N H.hahb.08 AF2 AF2
H.hahb 122 P H.hahb.09 AF2 AF2
H.HB 123 E H.HB.01 AF2 AF2
H.HB 124 N H.HB.02 AF2 AF2
H.HB 125 Q H.HB.03 AF2 AF2
H.HB 126 F H.HB.04 AF2 AF2
H.HB 127 R H.HB.05 AF2 AF2
H.HB 128 V H.HB.06 AF2 AF2
H.HB 129 D H.HB.07 AF2 AF2
H.HB 130 Y H.HB.08 AF2 AF2
H.HB 131 I H.HB.09 AF2 AF2
H.HB 132 L H.HB.10 AF2 AF2
H.HB 133 S H.HB.11 AF2 AF2
H.HB 134 V H.HB.12 AF2 AF2
H.HB 135 M H.HB.13 AF2 AF2
H.HB 136 N H.HB.14 AF2 AF2
H.hbhc 137 V H.hbhc.01 AF2 AF2
H.hbhc 138 P H.hbhc.02 AF2 AF2
H.hbhc 139 D H.hbhc.03 AF2 AF2
H.hbhc 140 F H.hbhc.04 AF2 AF2
H.hbhc 141 D H.hbhc.13 AF2 AF2
H.hbhc 142 F H.hbhc.14 AF2 AF2
H.hbhc 143 P H.hbhc.15 AF2 AF2
H.HC 144 P H.HC.01 AF2 AF2
H.HC 145 E H.HC.02 AF2 AF2
H.HC 146 F H.HC.03 AF2 AF2
H.HC 147 Y H.HC.04 AF2 AF2
H.HC 148 E H.HC.05 AF2 AF2
H.HC 149 H H.HC.06 AF2 AF2
H.HC 150 A H.HC.07 AF2 AF2
H.HC 151 K H.HC.08 AF2 AF2
H.HC 152 A H.HC.09 AF2 AF2
H.HC 153 L H.HC.10 AF2 AF2
H.HC 154 W H.HC.11 AF2 AF2
H.HC 155 E H.HC.12 AF2 AF2
H.hchd 156 D H.hchd.01 AF2 AF2
H.HD 157 E H.HD.01 AF2 AF2
H.HD 158 G H.HD.02 AF2 AF2
H.HD 159 V H.HD.03 AF2 AF2
H.HD 160 R H.HD.04 AF2 AF2
H.HD 161 A H.HD.05 AF2 AF2
H.HD 162 C H.HD.06 AF2 AF2
H.HD 163 Y H.HD.07 AF2 AF2
H.HD 164 E H.HD.08 AF2 AF2
H.HD 165 R H.HD.09 AF2 AF2
H.HD 166 S H.HD.10 AF2 AF2
H.HD 167 N H.HD.11 AF2 AF2
H.HD 168 E H.HD.12 AF2 AF2
H.hdhe 169 Y H.hdhe.01 AF2 AF2
H.hdhe 170 Q H.hdhe.02 AF2 AF2
H.hdhe 171 L H.hdhe.03 AF2 AF2
H.hdhe 172 I H.hdhe.04 AF2 AF2
H.hdhe 173 D H.hdhe.05 AF2 AF2
H.HE 174 C H.HE.01 AF2 AF2
H.HE 175 A H.HE.02 AF2 AF2
H.HE 176 Q H.HE.03 AF2 AF2
H.HE 177 Y H.HE.04 AF2 AF2
H.HE 178 F H.HE.05 AF2 AF2
H.HE 179 L H.HE.06 AF2 AF2
H.HE 180 D H.HE.07 AF2 AF2
H.HE 181 K H.HE.08 AF2 AF2
H.HE 182 I H.HE.09 AF2 AF2
H.HE 183 D H.HE.10 AF2 AF2
H.HE 184 V H.HE.11 AF2 AF2
H.HE 185 I H.HE.12 AF2 AF2
H.HE 186 K H.HE.13 AF2 AF2
H.hehf 187 Q H.hehf.01 AF2 AF2
H.hehf 188 A H.hehf.02 AF2 AF2
H.hehf 189 D H.hehf.03 AF2 AF2
H.hehf 190 Y H.hehf.04 AF2 AF2
H.hehf 191 V H.hehf.05 AF2 AF2
H.hehf 192 P H.hehf.06 AF2 AF2
H.hehf 193 S H.hehf.07 AF2 AF2
H.HF 194 D H.HF.01 AF2 AF2
H.HF 195 Q H.HF.02 AF2 AF2
H.HF 196 D H.HF.03 AF2 AF2
H.HF 197 L H.HF.04 AF2 AF2
H.HF 198 L H.HF.05 AF2 AF2
H.HF 199 R H.HF.06 AF2 AF2
G.hfs2 200 C G.hfs2.01 AF2 AF2
G.hfs2 201 R G.hfs2.02 AF2 AF2
G.hfs2 202 V G.hfs2.03 AF2 AF2
G.hfs2 203 L G.hfs2.04 AF2 AF2
G.hfs2 204 T G.hfs2.05 Structure Structure
G.hfs2 205 S G.hfs2.06 Structure Structure
G.hfs2 206 G G.hfs2.07 Structure Structure
G.S2 207 I G.S2.01 Structure Structure
G.S2 208 F G.S2.02 Structure Structure
G.S2 209 E G.S2.03 Structure Structure
G.S2 210 T G.S2.04 Structure Structure
G.S2 211 K G.S2.05 Structure Structure
G.S2 212 F G.S2.06 Structure Structure
G.S2 213 Q G.S2.07 Structure Structure
G.S2 214 V G.S2.08 Structure Structure
G.s2s3 215 D G.s2s3.01 Structure Structure
G.s2s3 216 K G.s2s3.02 Structure Structure
G.S3 217 V G.S3.01 Structure Structure
G.S3 218 N G.S3.02 Structure Structure
G.S3 219 F G.S3.03 Structure Structure
G.S3 220 H G.S3.04 Structure Structure
G.S3 221 M G.S3.05 Structure Structure
G.S3 222 F G.S3.06 Structure Structure
G.S3 223 D G.S3.07 Structure Structure
G.S3 224 V G.S3.08 Structure Structure
G.s3h2 225 G G.s3h2.01 Structure Structure
G.s3h2 226 G G.s3h2.02 Structure AF2
G.s3h2 227 Q G.s3h2.03 Structure Structure
G.H2 228 R G.H2.01 Structure Structure
G.H2 229 D G.H2.02 Structure Structure
G.H2 230 E G.H2.03 Structure Structure
G.H2 231 R G.H2.04 Structure Structure
G.H2 232 R G.H2.05 Structure Structure
G.H2 233 K G.H2.06 Structure Structure
G.H2 234 W G.H2.07 Structure Structure
G.H2 235 I G.H2.08 Structure Structure
G.H2 236 Q G.H2.09 Structure Structure
G.H2 237 C G.H2.10 Structure Structure
G.h2s4 238 F G.h2s4.01 Structure Structure
G.h2s4 239 N G.h2s4.02 Structure Structure
G.h2s4 240 D G.h2s4.03 Structure Structure
G.h2s4 241 V G.h2s4.04 Structure Structure
G.h2s4 242 T G.h2s4.05 Structure Structure
G.S4 243 A G.S4.01 Structure Structure
G.S4 244 I G.S4.02 Structure Structure
G.S4 245 I G.S4.03 Structure Structure
G.S4 246 F G.S4.04 Structure Structure
G.S4 247 V G.S4.05 Structure Structure
G.S4 248 V G.S4.06 Structure Structure
G.S4 249 A G.S4.07 Structure Structure
G.s4h3 250 S G.s4h3.01 Structure Structure
G.s4h3 251 S G.s4h3.02 Structure Structure
G.s4h3 252 S G.s4h3.03 Structure Structure
G.s4h3 253 Y G.s4h3.04 Structure Structure
G.s4h3 254 N G.s4h3.05 AF2 AF2
G.s4h3 255 M G.s4h3.06 AF2 AF2
G.s4h3 256 V G.s4h3.07 AF2 AF2
G.s4h3 257 I G.s4h3.08 AF2 AF2
G.s4h3 258 R G.s4h3.09 AF2 AF2
G.s4h3 259 E G.s4h3.10 Structure Structure
G.s4h3 260 D G.s4h3.11 Structure Structure
G.s4h3 261 N G.s4h3.12 Structure Structure
G.s4h3 262 Q G.s4h3.13 Structure Structure
G.s4h3 263 T G.s4h3.14 Structure Structure
G.s4h3 264 N G.s4h3.15 Structure Structure
G.H3 265 R G.H3.01 Structure Structure
G.H3 266 L G.H3.02 Structure Structure
G.H3 267 Q G.H3.03 Structure Structure
G.H3 268 E G.H3.04 Structure AF2
G.H3 269 A G.H3.05 Structure Structure
G.H3 270 L G.H3.06 Structure Structure
G.H3 271 N G.H3.07 Structure AF2
G.H3 272 L G.H3.08 Structure Structure
G.H3 273 F G.H3.09 Structure Structure
G.H3 274 K G.H3.10 Structure AF2
G.H3 275 S G.H3.11 Structure Structure
G.H3 276 I G.H3.12 Structure Structure
G.H3 277 W G.H3.13 Structure Structure
G.H3 278 N G.H3.14 Structure Structure
G.H3 279 N G.H3.15 Structure Structure
G.H3 280 R G.H3.16 Structure AF2
G.H3 281 W G.H3.17 Structure Structure
G.H3 282 L G.H3.18 Structure Structure
G.h3s5 283 R G.h3s5.01 Structure Structure
G.h3s5 284 T G.h3s5.02 Structure AF2
G.h3s5 285 I G.h3s5.03 Structure AF2
G.S5 286 S G.S5.01 Structure Structure
G.S5 287 V G.S5.02 Structure Structure
G.S5 288 I G.S5.03 Structure Structure
G.S5 289 L G.S5.04 Structure Structure
G.S5 290 F G.S5.05 Structure Structure
G.S5 291 L G.S5.06 Structure Structure
G.S5 292 N G.S5.07 Structure Structure
G.s5hg 293 K G.s5hg.01 Structure Structure
G.HG 294 Q G.HG.01 Structure Structure
G.HG 295 D G.HG.02 Structure Structure
G.HG 296 L G.HG.03 Structure Structure
G.HG 297 L G.HG.04 Structure Structure
G.HG 298 A G.HG.05 Structure Structure
G.HG 299 E G.HG.06 Structure Structure
G.HG 300 K G.HG.07 Structure Structure
G.HG 301 V G.HG.08 Structure Structure
G.HG 302 L G.HG.09 Structure Structure
G.HG 303 A G.HG.10 Structure Structure
G.HG 304 G G.HG.11 Structure Structure
G.HG 305 K G.HG.12 Structure Structure
G.HG 306 S G.HG.13 Structure Structure
G.HG 307 K G.HG.14 Structure Structure
G.HG 308 I G.HG.15 Structure Structure
G.HG 309 E G.HG.16 Structure Structure
G.HG 310 D G.HG.17 Structure Structure
G.hgh4 311 Y G.hgh4.01 Structure Structure
G.hgh4 312 F G.hgh4.02 Structure Structure
G.hgh4 313 P G.hgh4.03 Structure Structure
G.hgh4 314 E G.hgh4.04 Structure Structure
G.hgh4 315 F G.hgh4.05 Structure Structure
G.hgh4 316 A G.hgh4.06 Structure Structure
G.hgh4 317 R G.hgh4.07 Structure Structure
G.hgh4 318 Y G.hgh4.08 Structure Structure
G.hgh4 319 T G.hgh4.09 Structure Structure
G.hgh4 320 T G.hgh4.10 Structure Structure
G.hgh4 321 P G.hgh4.11 Structure Structure
G.hgh4 322 E G.hgh4.12 Structure Structure
G.hgh4 323 D G.hgh4.13 Structure Structure
G.hgh4 324 A G.hgh4.14 Structure Structure
G.hgh4 325 T G.hgh4.15 Structure Structure
G.hgh4 326 P G.hgh4.16 Structure Structure
G.hgh4 327 E G.hgh4.17 Structure Structure
G.hgh4 328 P G.hgh4.18 Structure Structure
G.hgh4 329 G G.hgh4.19 Structure Structure
G.hgh4 330 E G.hgh4.20 Structure Structure
G.hgh4 331 D G.hgh4.21 Structure Structure
G.H4 332 P G.H4.01 Structure Structure
G.H4 333 R G.H4.02 Structure Structure
G.H4 334 V G.H4.03 Structure Structure
G.H4 335 T G.H4.04 Structure Structure
G.H4 336 R G.H4.05 Structure Structure
G.H4 337 A G.H4.06 Structure Structure
G.H4 338 K G.H4.07 Structure Structure
G.H4 339 Y G.H4.08 Structure Structure
G.H4 340 F G.H4.10 Structure Structure
G.H4 341 I G.H4.11 Structure Structure
G.H4 342 R G.H4.12 Structure Structure
G.H4 343 D G.H4.13 Structure Structure
G.H4 344 E G.H4.14 Structure Structure
G.H4 345 F G.H4.15 Structure Structure
G.H4 346 L G.H4.16 Structure Structure
G.H4 347 R G.H4.17 Structure Structure
G.h4s6 348 I G.h4s6.01 Structure Structure
G.h4s6 349 S G.h4s6.02 Structure Structure
G.h4s6 350 T G.h4s6.03 Structure Structure
G.h4s6 351 A G.h4s6.04 Structure Structure
G.h4s6 352 S G.h4s6.08 Structure Structure
G.h4s6 353 G G.h4s6.09 Structure Structure
G.h4s6 354 D G.h4s6.10 Structure Structure
G.h4s6 355 G G.h4s6.11 Structure Structure
G.h4s6 356 R G.h4s6.12 Structure Structure
G.h4s6 357 H G.h4s6.13 Structure Structure
G.h4s6 358 Y G.h4s6.20 Structure Structure
G.S6 359 C G.S6.01 Structure Structure
G.S6 360 Y G.S6.02 Structure Structure
G.S6 361 P G.S6.03 Structure Structure
G.S6 362 H G.S6.04 Structure Structure
G.S6 363 F G.S6.05 Structure Structure
G.s6h5 364 T G.s6h5.01 Structure Structure
G.s6h5 365 C G.s6h5.02 Structure Structure
G.s6h5 366 A G.s6h5.03 Structure Structure
G.s6h5 367 V G.s6h5.04 Structure Structure
G.s6h5 368 D G.s6h5.05 Structure Structure
G.H5 369 T G.H5.01 Structure Structure
G.H5 370 E G.H5.02 Structure Structure
G.H5 371 N G.H5.03 Structure Structure
G.H5 372 I G.H5.04 Structure Structure
G.H5 373 R G.H5.05 Structure Structure
G.H5 374 R G.H5.06 Structure Structure
G.H5 375 V G.H5.07 Structure Structure
G.H5 376 F G.H5.08 Structure Structure
G.H5 377 N G.H5.09 Structure Structure
G.H5 378 D G.H5.10 Structure Structure
G.H5 379 C G.H5.11 Structure Structure
G.H5 380 R G.H5.12 Structure Structure
G.H5 381 D G.H5.13 Structure Structure
G.H5 382 I G.H5.14 Structure Structure
G.H5 383 I G.H5.15 Structure Structure
G.H5 384 Q G.H5.16 Structure Structure
G.H5 385 R G.H5.17 Structure Structure
G.H5 386 M G.H5.18 Structure Structure
G.H5 387 H G.H5.19 Structure Structure
G.H5 388 L G.H5.20 Structure Structure
G.H5 389 R G.H5.21 Structure Structure
G.H5 390 Q G.H5.22 Structure Structure
G.H5 391 Y G.H5.23 Structure Structure
G.H5 392 E G.H5.24 Structure Structure
G.H5 393 L G.H5.25 Structure Structure
G.H5 394 L G.H5.26 Structure Structure

REFINED GPCR RESIDUES

Residue backbones - 272 from structure (69.9%), 117 from model (30.1%)
Residue sidechains - 272 from structure (69.9%), 117 from model (30.1%)
Segment Seq.num. AA GPCRdb# Backbone from Sidechain from
N-term 1 M - AF2 AF2
N-term 2 M - AF2 AF2
N-term 3 D - AF2 AF2
N-term 4 V - AF2 AF2
N-term 5 N - AF2 AF2
N-term 6 S - AF2 AF2
N-term 7 S - AF2 AF2
N-term 8 G - AF2 AF2
N-term 9 R - AF2 AF2
N-term 10 P - AF2 AF2
N-term 11 D - AF2 AF2
N-term 12 L - AF2 AF2
N-term 13 Y - AF2 AF2
N-term 14 G - AF2 AF2
N-term 15 H - AF2 AF2
N-term 16 L - AF2 AF2
N-term 17 R - AF2 AF2
N-term 18 S - AF2 AF2
N-term 19 F - AF2 AF2
N-term 20 L - AF2 AF2
N-term 21 L - AF2 AF2
N-term 22 P - AF2 AF2
N-term 23 E - AF2 AF2
N-term 24 V - AF2 AF2
N-term 25 G - AF2 AF2
N-term 26 R - AF2 AF2
N-term 27 G - AF2 AF2
N-term 28 L - AF2 AF2
N-term 29 P - AF2 AF2
N-term 30 D - AF2 AF2
N-term 31 L - AF2 AF2
N-term 32 S - AF2 AF2
N-term 33 P - AF2 AF2
N-term 34 D - AF2 AF2
N-term 35 G - AF2 AF2
N-term 36 G - AF2 AF2
N-term 37 A - AF2 AF2
N-term 38 D - AF2 AF2
N-term 39 P - AF2 AF2
N-term 40 V - AF2 AF2
N-term 41 A - AF2 AF2
N-term 42 G - AF2 AF2
N-term 43 S - AF2 AF2
N-term 44 W - AF2 AF2
N-term 45 A - AF2 AF2
N-term 46 P - AF2 AF2
N-term 47 H - AF2 AF2
N-term 48 L - AF2 AF2
N-term 49 L - AF2 AF2
N-term 50 S - AF2 AF2
N-term 51 E - AF2 AF2
N-term 52 V - AF2 AF2
N-term 53 T - AF2 AF2
N-term 54 A - AF2 AF2
N-term 55 S - AF2 AF2
N-term 56 P - AF2 AF2
N-term 57 A - AF2 AF2
N-term 58 P - AF2 AF2
N-term 59 T - AF2 AF2
N-term 60 W - AF2 AF2
N-term 61 D - AF2 AF2
N-term 62 A - AF2 AF2
N-term 63 P - AF2 AF2
N-term 64 P - AF2 AF2
N-term 65 D - AF2 AF2
N-term 66 N - AF2 AF2
N-term 67 A - AF2 AF2
N-term 68 S - AF2 AF2
N-term 69 G - AF2 AF2
N-term 70 C - AF2 AF2
N-term 71 G - AF2 AF2
N-term 72 E - AF2 AF2
N-term 73 Q - AF2 AF2
N-term 74 I - AF2 AF2
N-term 75 N - AF2 AF2
N-term 76 Y - AF2 AF2
TM1 77 G 1.28x28 AF2 AF2
TM1 78 R 1.29x29 AF2 AF2
TM1 79 V 1.30x30 AF2 AF2
TM1 80 E 1.31x31 AF2 AF2
TM1 81 K 1.32x32 AF2 AF2
TM1 82 V 1.33x33 AF2 AF2
TM1 83 V 1.34x34 Structure Structure
TM1 84 I 1.35x35 Structure Structure
TM1 85 G 1.36x36 Structure Structure
TM1 86 S 1.37x37 Structure Structure
TM1 87 I 1.38x38 Structure Structure
TM1 88 L 1.39x39 Structure Structure
TM1 89 T 1.40x40 Structure Structure
TM1 90 L 1.41x41 Structure Structure
TM1 91 I 1.42x42 Structure Structure
TM1 92 T 1.43x43 Structure Structure
TM1 93 L 1.44x44 Structure Structure
TM1 94 L 1.45x45 Structure Structure
TM1 95 T 1.46x46 Structure Structure
TM1 96 I 1.47x47 Structure Structure
TM1 97 A 1.48x48 Structure Structure
TM1 98 G 1.49x49 Structure Structure
TM1 99 N 1.50x50 Structure Structure
TM1 100 C 1.51x51 Structure Structure
TM1 101 L 1.52x52 Structure Structure
TM1 102 V 1.53x53 Structure Structure
TM1 103 V 1.54x54 Structure Structure
TM1 104 I 1.55x55 Structure Structure
TM1 105 S 1.56x56 Structure Structure
TM1 106 V 1.57x57 Structure Structure
TM1 107 C 1.58x58 Structure Structure
TM1 108 F 1.59x59 Structure Structure
TM1 109 V 1.60x60 Structure Structure
ICL1 110 K 12.48x48 Structure Structure
ICL1 111 K 12.49x49 Structure Structure
ICL1 112 L 12.50x50 Structure Structure
ICL1 113 R 12.51x51 Structure Structure
TM2 114 Q 2.37x37 Structure Structure
TM2 115 P 2.38x38 Structure Structure
TM2 116 S 2.39x39 Structure Structure
TM2 117 N 2.40x40 Structure Structure
TM2 118 Y 2.41x41 Structure Structure
TM2 119 L 2.42x42 Structure Structure
TM2 120 I 2.43x43 Structure Structure
TM2 121 V 2.44x44 Structure Structure
TM2 122 S 2.45x45 Structure Structure
TM2 123 L 2.46x46 Structure Structure
TM2 124 A 2.47x47 Structure Structure
TM2 125 L 2.48x48 Structure Structure
TM2 126 A 2.49x49 Structure Structure
TM2 127 D 2.50x50 Structure Structure
TM2 128 L 2.51x51 Structure Structure
TM2 129 S 2.52x52 Structure Structure
TM2 130 V 2.53x53 Structure Structure
TM2 131 A 2.54x54 Structure Structure
TM2 132 V 2.55x55 Structure Structure
TM2 133 A 2.56x551 Structure Structure
TM2 134 V 2.57x56 Structure Structure
TM2 135 M 2.58x57 Structure Structure
TM2 136 P 2.59x58 Structure Structure
TM2 137 F 2.60x59 Structure Structure
TM2 138 V 2.61x60 Structure Structure
TM2 139 S 2.62x61 Structure Structure
TM2 140 V 2.63x62 Structure Structure
TM2 141 T 2.64x63 Structure Structure
TM2 142 D 2.65x64 Structure Structure
TM2 143 L 2.66x65 Structure Structure
TM2 144 I 2.67x66 Structure Structure
TM2 145 G 2.68x67 Structure Structure
TM2 146 G 2.69x68 Structure Structure
ECL1 147 K 23.49x49 Structure Structure
ECL1 148 W 23.50x50 Structure Structure
ECL1 149 I 23.51x51 Structure Structure
ECL1 150 F 23.52x52 Structure Structure
TM3 151 G 3.21x21 Structure Structure
TM3 152 H 3.22x22 Structure Structure
TM3 153 F 3.23x23 Structure Structure
TM3 154 F 3.24x24 Structure Structure
TM3 155 C 3.25x25 Structure Structure
TM3 156 N 3.26x26 Structure Structure
TM3 157 V 3.27x27 Structure Structure
TM3 158 F 3.28x28 Structure Structure
TM3 159 I 3.29x29 Structure Structure
TM3 160 A 3.30x30 Structure Structure
TM3 161 M 3.31x31 Structure Structure
TM3 162 D 3.32x32 Structure Structure
TM3 163 V 3.33x33 Structure Structure
TM3 164 M 3.34x34 Structure Structure
TM3 165 C 3.35x35 Structure Structure
TM3 166 C 3.36x36 Structure Structure
TM3 167 T 3.37x37 Structure Structure
TM3 168 A 3.38x38 Structure Structure
TM3 169 S 3.39x39 Structure Structure
TM3 170 I 3.40x40 Structure Structure
TM3 171 M 3.41x41 Structure Structure
TM3 172 T 3.42x42 Structure Structure
TM3 173 L 3.43x43 Structure Structure
TM3 174 C 3.44x44 Structure Structure
TM3 175 V 3.45x45 Structure Structure
TM3 176 I 3.46x46 Structure Structure
TM3 177 S 3.47x47 Structure Structure
TM3 178 I 3.48x48 Structure Structure
TM3 179 D 3.49x49 Structure Structure
TM3 180 R 3.50x50 Structure Structure
TM3 181 Y 3.51x51 Structure Structure
TM3 182 L 3.52x52 Structure Structure
TM3 183 G 3.53x53 Structure Structure
TM3 184 I 3.54x54 Structure Structure
TM3 185 T 3.55x55 Structure Structure
TM3 186 R 3.56x56 Structure Structure
ICL2 187 P 34.50x50 Structure Structure
ICL2 188 L 34.51x51 Structure Structure
ICL2 189 T 34.52x52 Structure Structure
ICL2 190 Y 34.53x53 Structure Structure
ICL2 191 P 34.54x54 Structure Structure
ICL2 192 V 34.55x55 Structure Structure
ICL2 193 R 34.56x56 Structure Structure
ICL2 194 Q 34.57x57 Structure Structure
TM4 195 N 4.38x38 Structure Structure
TM4 196 G 4.39x39 Structure Structure
TM4 197 K 4.40x40 Structure Structure
TM4 198 C 4.41x41 Structure Structure
TM4 199 M 4.42x42 Structure Structure
TM4 200 A 4.43x43 Structure Structure
TM4 201 K 4.44x44 Structure Structure
TM4 202 M 4.45x45 Structure Structure
TM4 203 I 4.46x46 Structure Structure
TM4 204 L 4.47x47 Structure Structure
TM4 205 S 4.48x48 Structure Structure
TM4 206 V 4.49x49 Structure Structure
TM4 207 W 4.50x50 Structure Structure
TM4 208 L 4.51x51 Structure Structure
TM4 209 L 4.52x52 Structure Structure
TM4 210 S 4.53x53 Structure Structure
TM4 211 A 4.54x54 Structure Structure
TM4 212 S 4.55x55 Structure Structure
TM4 213 I 4.56x56 Structure Structure
TM4 214 T 4.57x57 Structure Structure
TM4 215 L 4.58x58 Structure Structure
TM4 216 P 4.59x59 Structure Structure
TM4 217 P 4.60x60 Structure Structure
TM4 218 L 4.61x61 Structure Structure
TM4 219 F 4.62x62 Structure Structure
TM4 220 G 4.63x63 Structure Structure
ECL2 221 W - Structure Structure
ECL2 222 A - Structure Structure
ECL2 223 Q - Structure Structure
ECL2 224 N - Structure Structure
ECL2 225 V - Structure Structure
ECL2 226 N - Structure Structure
ECL2 227 D - Structure Structure
ECL2 228 D - Structure Structure
ECL2 229 K - Structure Structure
ECL2 230 V - Structure Structure
ECL2 231 C 45.50x50 Structure Structure
ECL2 232 L 45.51x51 Structure Structure
ECL2 233 I 45.52x52 Structure Structure
ECL2 234 S - Structure Structure
ECL2 235 Q - Structure Structure
TM5 236 D 5.35x36 Structure Structure
TM5 237 F 5.36x37 Structure Structure
TM5 238 G 5.37x38 Structure Structure
TM5 239 Y 5.38x39 Structure Structure
TM5 240 T 5.39x40 Structure Structure
TM5 241 I 5.40x41 Structure Structure
TM5 242 Y 5.41x42 Structure Structure
TM5 243 S 5.42x43 Structure Structure
TM5 244 T 5.43x44 Structure Structure
TM5 245 A 5.44x45 Structure Structure
TM5 246 V 5.45x46 Structure Structure
TM5 247 A 5.46x461 Structure Structure
TM5 248 F 5.47x47 Structure Structure
TM5 249 Y 5.48x48 Structure Structure
TM5 250 I 5.49x49 Structure Structure
TM5 251 P 5.50x50 Structure Structure
TM5 252 M 5.51x51 Structure Structure
TM5 253 S 5.52x52 Structure Structure
TM5 254 V 5.53x53 Structure Structure
TM5 255 M 5.54x54 Structure Structure
TM5 256 L 5.55x55 Structure Structure
TM5 257 F 5.56x56 Structure Structure
TM5 258 M 5.57x57 Structure Structure
TM5 259 Y 5.58x58 Structure Structure
TM5 260 Y 5.59x59 Structure Structure
TM5 261 Q 5.60x60 Structure Structure
TM5 262 I 5.61x61 Structure Structure
TM5 263 Y 5.62x62 Structure Structure
TM5 264 K 5.63x63 Structure Structure
TM5 265 A 5.64x64 Structure Structure
TM5 266 A 5.65x65 Structure Structure
TM5 267 R 5.66x66 Structure Structure
TM5 268 K 5.67x67 Structure Structure
TM5 269 S 5.68x68 Structure Structure
TM5 270 A 5.69x69 Structure Structure
TM5 271 A 5.70x70 Structure Structure
TM5 272 K 5.71x71 Structure Structure
TM5 273 H 5.72x72 Structure Structure
TM5 274 K 5.73x73 Structure Structure
TM5 275 F 5.74x74 Structure Structure
TM5 276 P 5.75x75 Structure Structure
TM5 277 G 5.76x76 Structure Structure
ICL3 278 F - Structure Structure
ICL3 279 P - Structure Structure
ICL3 280 R - AF2 AF2
ICL3 281 V - AF2 AF2
ICL3 282 E - AF2 AF2
ICL3 283 P - AF2 AF2
ICL3 284 D - AF2 AF2
ICL3 309 L - AF2 AF2
ICL3 310 K - AF2 AF2
ICL3 311 H - AF2 AF2
ICL3 312 E - AF2 AF2
ICL3 313 R - AF2 AF2
ICL3 314 K - AF2 AF2
ICL3 315 N - AF2 AF2
TM6 316 I 6.24x24 AF2 AF2
TM6 317 S 6.25x25 AF2 AF2
TM6 318 I 6.26x26 AF2 AF2
TM6 319 F 6.27x27 AF2 AF2
TM6 320 K 6.28x28 AF2 AF2
TM6 321 R 6.29x29 AF2 AF2
TM6 322 E 6.30x30 AF2 AF2
TM6 323 Q 6.31x31 AF2 AF2
TM6 324 K 6.32x32 Structure Structure
TM6 325 A 6.33x33 Structure Structure
TM6 326 A 6.34x34 Structure Structure
TM6 327 T 6.35x35 Structure Structure
TM6 328 T 6.36x36 Structure Structure
TM6 329 L 6.37x37 Structure Structure
TM6 330 G 6.38x38 Structure Structure
TM6 331 I 6.39x39 Structure Structure
TM6 332 I 6.40x40 Structure Structure
TM6 333 V 6.41x41 Structure Structure
TM6 334 G 6.42x42 Structure Structure
TM6 335 A 6.43x43 Structure Structure
TM6 336 F 6.44x44 Structure Structure
TM6 337 T 6.45x45 Structure Structure
TM6 338 V 6.46x46 Structure Structure
TM6 339 C 6.47x47 Structure Structure
TM6 340 W 6.48x48 Structure Structure
TM6 341 L 6.49x49 Structure Structure
TM6 342 P 6.50x50 Structure Structure
TM6 343 F 6.51x51 Structure Structure
TM6 344 F 6.52x52 Structure Structure
TM6 345 L 6.53x53 Structure Structure
TM6 346 L 6.54x54 Structure Structure
TM6 347 S 6.55x55 Structure Structure
TM6 348 T 6.56x56 Structure Structure
TM6 349 A 6.57x57 Structure Structure
TM6 350 R 6.58x58 Structure Structure
TM6 351 P 6.59x59 Structure Structure
TM6 352 F 6.60x60 Structure Structure
TM6 353 I 6.61x61 Structure Structure
ECL3 354 C - Structure Structure
ECL3 355 G - AF2 AF2
ECL3 356 T - AF2 AF2
ECL3 357 S - AF2 AF2
ECL3 358 C - AF2 AF2
ECL3 359 S - AF2 AF2
ECL3 360 C - Structure Structure
ECL3 361 I - Structure Structure
TM7 362 P 7.31x30 Structure Structure
TM7 363 L 7.32x31 Structure Structure
TM7 364 W 7.33x32 Structure Structure
TM7 365 V 7.34x33 Structure Structure
TM7 366 E 7.35x34 Structure Structure
TM7 367 R 7.36x35 Structure Structure
TM7 368 T 7.37x36 Structure Structure
TM7 369 F 7.38x37 Structure Structure
TM7 370 L 7.39x38 Structure Structure
TM7 371 W 7.40x39 Structure Structure
TM7 372 L 7.41x40 Structure Structure
TM7 373 G 7.42x41 Structure Structure
TM7 374 Y 7.43x42 Structure Structure
TM7 375 A 7.44x43 Structure Structure
TM7 376 N 7.45x45 Structure Structure
TM7 377 S 7.46x46 Structure Structure
TM7 378 L 7.47x47 Structure Structure
TM7 379 I 7.48x48 Structure Structure
TM7 380 N 7.49x49 Structure Structure
TM7 381 P 7.50x50 Structure Structure
TM7 382 F 7.51x51 Structure Structure
TM7 383 I 7.52x52 Structure Structure
TM7 384 Y 7.53x53 Structure Structure
TM7 385 A 7.54x54 Structure Structure
TM7 386 F 7.55x55 Structure Structure
TM7 387 F 7.56x56 Structure Structure
H8 388 N 8.47x47 Structure Structure
H8 389 R 8.48x48 Structure Structure
H8 390 D 8.49x49 Structure Structure
H8 391 L 8.50x50 Structure Structure
H8 392 R 8.51x51 Structure Structure
H8 393 T 8.52x52 Structure Structure
H8 394 T 8.53x53 Structure Structure
H8 395 Y 8.54x54 Structure Structure
H8 396 R 8.55x55 Structure Structure
H8 397 S 8.56x56 Structure Structure
H8 398 L 8.57x57 Structure Structure
H8 399 L 8.58x58 Structure Structure
H8 400 Q 8.59x59 Structure Structure
H8 401 C 8.60x60 Structure Structure
H8 402 Q 8.61x61 Structure Structure
H8 403 Y 8.62x62 Structure Structure
C-term 404 R - AF2 AF2
C-term 405 N - AF2 AF2
C-term 406 I - AF2 AF2
C-term 407 N - AF2 AF2
C-term 408 R - AF2 AF2
C-term 409 K - AF2 AF2
C-term 410 L - AF2 AF2
C-term 411 S - AF2 AF2
C-term 412 A - AF2 AF2
C-term 413 A - AF2 AF2



GPCR - G protein interface interactions



The biflare plot is a modified version of a flareplot, where lines are drawn between an inner concentric circle (Gα residues) and an outer concentric circle (GPCR residues) depicting the interface interactions.
Different interaction types are shown with different line types (aromatic - solid, hydrophobic - dashed, ionic - long dashed, polar - dotted, Van der Waals - dash-dot).
The interactive features include filtering on interaction type, segments, residues and backbone or sidechain interactions.


Interaction cut-off:

Residue numbering:

GPCR-G protein backbone (bb) or sidechain (sc):





Structures

Sequence Color

Gα, Gβ, Gγ, GPCR
Interaction cut-off: strict (stick), loose (line)

NGL is a WebGL based 3D viewer powered by MMTF.

Interaction
type		 GPCR
Segment
AA
Number		 Generic
number		 Gα
segment
AA
Number		 Generic
number
Hydrophobic ICL2 P 187 34x50 G.H5 R 380 G.H5.12
Van-der-waals ICL2 P 187 34x50 G.H5 R 380 G.H5.12
Hydrophobic TM5 A 266 5x65 G.H5 L 388 G.H5.20
Van-der-waals TM5 A 266 5x65 G.H5 L 388 G.H5.20
Polar TM3 T 185 3x55 G.H5 R 380 G.H5.12
Hydrophobic ICL2 L 188 34x51 G.H5 C 379 G.H5.11
Polar TM6 A 325 6x33 G.H5 L 393 G.H5.25
Hydrophobic TM6 A 325 6x33 G.H5 L 393 G.H5.25
Van-der-waals TM6 A 325 6x33 G.H5 L 393 G.H5.25
Aromatic TM3 R 180 3x50 G.H5 Y 391 G.H5.23
Hydrophobic TM3 R 180 3x50 G.H5 Y 391 G.H5.23
Polar ICL2 P 191 34x54 G.hns1 R 38 G.hns1.02
Van-der-waals ICL2 P 191 34x54 G.hns1 R 38 G.hns1.02
Van-der-waals TM6 R 321 6x29 G.H5 R 385 G.H5.17
Polar TM5 K 272 5x71 G.h4s6 Y 358 G.h4s6.20
Hydrophobic ICL2 L 188 34x51 G.S1 H 41 G.S1.02
Ionic TM5 K 272 5x71 G.H5 D 381 G.H5.13
Polar TM5 K 272 5x71 G.H5 D 381 G.H5.13
Hydrophobic TM5 K 272 5x71 G.H5 D 381 G.H5.13
Van-der-waals TM5 K 272 5x71 G.H5 D 381 G.H5.13
Polar TM5 H 273 5x72 G.h4s6 Y 358 G.h4s6.20
Aromatic TM5 H 273 5x72 G.h4s6 Y 358 G.h4s6.20
Hydrophobic TM5 H 273 5x72 G.h4s6 Y 358 G.h4s6.20
Van-der-waals TM5 H 273 5x72 G.h4s6 Y 358 G.h4s6.20
Ionic TM5 H 273 5x72 G.H5 D 381 G.H5.13
Polar TM5 H 273 5x72 G.H5 D 381 G.H5.13
Hydrophobic TM5 H 273 5x72 G.H5 D 381 G.H5.13
Van-der-waals TM5 H 273 5x72 G.H5 D 381 G.H5.13
Hydrophobic TM5 H 273 5x72 G.S6 Y 360 G.S6.02
Hydrophobic ICL2 L 188 34x51 G.H5 R 380 G.H5.12
Van-der-waals ICL2 L 188 34x51 G.H5 R 380 G.H5.12
Polar TM3 G 183 3x53 G.H5 H 387 G.H5.19
Hydrophobic TM3 I 184 3x54 G.H5 L 388 G.H5.20
Hydrophobic ICL2 L 188 34x51 G.H5 I 383 G.H5.15
Van-der-waals ICL2 L 188 34x51 G.H5 I 383 G.H5.15
Ionic TM6 K 324 6x32 G.H5 E 392 G.H5.24
Polar TM6 K 324 6x32 G.H5 E 392 G.H5.24
Van-der-waals TM6 K 324 6x32 G.H5 E 392 G.H5.24
Polar ICL2 V 192 34x55 G.hns1 R 38 G.hns1.02
Hydrophobic TM3 I 184 3x54 G.H5 H 387 G.H5.19
Hydrophobic TM5 I 262 5x61 G.H5 L 393 G.H5.25
Van-der-waals TM5 I 262 5x61 G.H5 L 393 G.H5.25
Hydrophobic ICL2 L 188 34x51 G.S3 F 219 G.S3.03
Hydrophobic TM5 P 276 5x75 G.hgh4 D 323 G.hgh4.13
Van-der-waals TM5 P 276 5x75 G.hgh4 D 323 G.hgh4.13
Hydrophobic ICL3 V 281 - G.hgh4 R 317 G.hgh4.07
Van-der-waals ICL3 V 281 - G.hgh4 R 317 G.hgh4.07
Hydrophobic TM6 K 324 6x32 G.H5 L 393 G.H5.25
Hydrophobic TM3 I 184 3x54 G.H5 Y 391 G.H5.23
Hydrophobic ICL2 L 188 34x51 G.H5 F 376 G.H5.08
Van-der-waals ICL2 L 188 34x51 G.H5 F 376 G.H5.08
Hydrophobic ICL2 P 187 34x50 G.H5 H 387 G.H5.19
Hydrophobic ICL2 P 187 34x50 G.H5 Q 384 G.H5.16
Hydrophobic ICL3 F 278 - G.H4 L 346 G.H4.16
Van-der-waals ICL3 F 278 - G.H4 L 346 G.H4.16
Polar H8 R 389 8x48 G.H5 R 389 G.H5.21
Hydrophobic H8 R 389 8x48 G.H5 R 389 G.H5.21
Van-der-waals H8 R 389 8x48 G.H5 R 389 G.H5.21
Ionic H8 R 392 8x51 G.H5 E 392 G.H5.24
Hydrophobic ICL3 P 279 - G.hgh4 P 321 G.hgh4.11
Van-der-waals ICL3 P 279 - G.hgh4 P 321 G.hgh4.11
Hydrophobic ICL3 P 279 - G.hgh4 T 319 G.hgh4.09
Van-der-waals ICL3 P 279 - G.hgh4 T 319 G.hgh4.09
Ionic H8 R 389 8x48 G.H5 E 392 G.H5.24
Polar H8 R 389 8x48 G.H5 E 392 G.H5.24
Hydrophobic H8 R 389 8x48 G.H5 E 392 G.H5.24
Van-der-waals H8 R 389 8x48 G.H5 E 392 G.H5.24
Hydrophobic ICL3 F 278 - G.H4 D 343 G.H4.13
Van-der-waals ICL3 F 278 - G.H4 D 343 G.H4.13
Hydrophobic TM5 S 269 5x68 G.H5 L 388 G.H5.20
Hydrophobic TM5 A 266 5x65 G.H5 L 393 G.H5.25
Hydrophobic TM5 F 275 5x74 G.H4 L 346 G.H4.16
Van-der-waals TM5 F 275 5x74 G.H4 L 346 G.H4.16
Hydrophobic ICL3 P 279 - G.hgh4 Y 318 G.hgh4.08
Polar H8 R 389 8x48 G.H5 Q 390 G.H5.22
Van-der-waals H8 R 389 8x48 G.H5 Q 390 G.H5.22
Hydrophobic TM5 F 275 5x74 G.h4s6 T 350 G.h4s6.03
Hydrophobic ICL2 V 192 34x55 G.hns1 A 39 G.hns1.03
Van-der-waals ICL2 V 192 34x55 G.hns1 A 39 G.hns1.03
Hydrophobic ICL3 F 278 - G.h4s6 T 350 G.h4s6.03
Van-der-waals ICL3 F 278 - G.h4s6 T 350 G.h4s6.03
Hydrophobic ICL3 R 280 - G.H4 R 347 G.H4.17
Van-der-waals ICL3 R 280 - G.H4 R 347 G.H4.17
Hydrophobic TM3 I 184 3x54 G.H5 L 393 G.H5.25
Polar TM3 I 184 3x54 G.H5 Q 384 G.H5.16
Hydrophobic TM3 I 184 3x54 G.H5 Q 384 G.H5.16
Van-der-waals TM3 I 184 3x54 G.H5 Q 384 G.H5.16
Polar H8 R 389 8x48 G.H5 L 394 G.H5.26
Van-der-waals H8 R 389 8x48 G.H5 L 394 G.H5.26
Hydrophobic ICL3 P 279 - G.H4 D 343 G.H4.13
Hydrophobic ICL3 F 278 - G.H4 R 347 G.H4.17
Van-der-waals ICL3 F 278 - G.H4 R 347 G.H4.17
Polar ICL2 Q 194 34x57 G.hns1 R 38 G.hns1.02
Van-der-waals ICL2 Q 194 34x57 G.hns1 R 38 G.hns1.02
Aromatic TM5 F 275 5x74 G.h4s6 Y 358 G.h4s6.20
Hydrophobic TM5 F 275 5x74 G.h4s6 Y 358 G.h4s6.20
Van-der-waals TM5 F 275 5x74 G.h4s6 Y 358 G.h4s6.20
Hydrophobic TM6 R 321 6x29 G.H5 L 394 G.H5.26
Hydrophobic TM5 F 275 5x74 G.S6 P 361 G.S6.03
Polar TM5 S 269 5x68 G.H5 Q 384 G.H5.16
Hydrophobic ICL2 P 187 34x50 G.H5 I 383 G.H5.15
Van-der-waals ICL2 P 187 34x50 G.H5 I 383 G.H5.15
Hydrophobic ICL2 P 191 34x54 G.H5 H 387 G.H5.19
Hydrophobic TM5 F 275 5x74 G.S6 C 359 G.S6.01
Van-der-waals TM5 F 275 5x74 G.S6 C 359 G.S6.01
Hydrophobic TM7 F 387 7x56 G.H5 E 392 G.H5.24
Polar TM6 T 328 6x36 G.H5 E 392 G.H5.24
Polar TM5 H 273 5x72 G.H5 R 385 G.H5.17
Aromatic TM5 H 273 5x72 G.H5 R 385 G.H5.17
Hydrophobic TM5 H 273 5x72 G.H5 R 385 G.H5.17
Van-der-waals TM5 H 273 5x72 G.H5 R 385 G.H5.17