haloperidol



haloperidol


SMILES O=C(CCCN1CCC(O)(c2ccc(Cl)cc2)CC1)c1ccc(F)cc1
InChIKey LNEPOXFFQSENCJ-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 375.1

Database connections

Structure pdb 6LUQ
Ligand site mutations 5-HT2A 5-HT2C D1 D2 D3 D5

Bioactivities

Receptor Activity Source
Protein Gene Species Family Class Type Min Avg Max Database
Receptor Activity Source
Protein Gene Species Family Class Type Min Avg Max Database

haloperidol


Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug Yes

Distribution across phases (no. indications)

Phase I 0
Phase II 5
Phase III 16
Phase IV 35

Database connections

Structure pdb 6LUQ
Ligand site mutations 5-HT2A 5-HT2C D1 D2 D3 D5

Sankey plot

Drug Information

Target Disease
Gene Protein Receptor family Ligand type Class Name Phase ICD11 ATC Association score