olorinab


SMILES OC[C@H](C(C)(C)C)NC(=O)c1nn(c2c1C[C@H]1[C@@H]2C1)c1ncc[n+](c1)[O-]
InChIKey ACSQLTBPYZSGBA-GMXVVIOVSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 4
Molecular weight (Da) 357.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug Yes

Database connections

Structure pdb 8GUQ

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CB1 CNR1 Human Cannabinoid A pEC50 5.0 5.0 5.0 Guide to Pharmacology
CB2 CNR2 Human Cannabinoid A pEC50 8.21 8.21 8.21 Guide to Pharmacology
CB1 CNR1 Rat Cannabinoid A pEC50 5.0 5.0 5.0 Guide to Pharmacology
CB2 CNR2 Rat Cannabinoid A pEC50 8.12 8.12 8.12 Guide to Pharmacology
CB2 CNR2 Rat Cannabinoid A pEC50 8.12 8.12 8.12 ChEMBL
CB2 CNR2 Human Cannabinoid A pEC50 8.21 8.21 8.21 ChEMBL