spiperone


SMILES Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)C(=O)NCN2c1ccccc1
InChIKey DKGZKTPJOSAWFA-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 395.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug Yes

Database connections

Structure pdb 7DFP
Ligand site mutations α1A α1B 5-HT1A D1 D2 D3

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
ETB EDNRB Human Endothelin A pIC50 7.16 7.16 7.16 ChEMBL
ETA EDNRA Human Endothelin A pIC50 5.17 5.17 5.17 ChEMBL
ETB EDNRB Human Endothelin A pIC50 7.2 7.2 7.2 Guide to Pharmacology