ZM-241385


SMILES Oc1ccc(cc1)CCNc1nc(N)n2c(n1)nc(n2)c1ccco1
InChIKey PWTBZOIUWZOPFT-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 9
Hydrogen bond donors 3
Rotatable bonds 5
Molecular weight (Da) 337.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug Yes

Database connections

Structure pdb 3EML 3PWH 3VG9 3VGA 4EIY 5IU4 5K2A 5K2B 5K2C 5K2D 5UVI 5JTB 5NLX 5NM2 5NM4 5VRA 6AQF 5OLG 6MH8 6JZH 6PS7 6S0Q 6S0L 6WQA 6LPJ 6LPK 6LPL 7RM5 7T32 8FYN
Ligand site mutations A2A A2B

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
SST2 SSR2 Human Somatostatin A pIC50 9.15 9.15 9.15 Guide to Pharmacology