DAMGO


SMILES None
InChIKey HPZJMUBDEAMBFI-WTNAPCKOSA-N
Sequence YAGFG

Chemical properties

Hydrogen bond acceptors None
Hydrogen bond donors None
Rotatable bonds None
Molecular weight (Da)

Drug properties

Molecular type Peptide
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Structure pdb 6DDF 8EFQ 6DDE

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
β1 ADRB1 Human Adrenoceptors A pKi 5.7 6.23 6.5 ChEMBL
β2 ADRB2 Human Adrenoceptors A pKi 7.48 7.93 8.59 ChEMBL
β2 ADRB2 Human Adrenoceptors A pKd 8.6 8.6 8.6 ChEMBL
D2 DRD2 Human Dopamine A pKi 4.89 4.89 4.89 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.79 5.79 5.79 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
β2 ADRB2 Human Adrenoceptors A pEC50 10.08 10.08 10.08 Guide to Pharmacology
β1 B0FL73 Guinea pig Adrenoceptors A pEC50 9.5 9.5 9.5 ChEMBL
β1 ADRB1 Human Adrenoceptors A pEC50 7.07 7.4 7.9 ChEMBL
β3 ADRB3 Human Adrenoceptors A pEC50 7.6 7.6 7.6 ChEMBL
β2 ADRB2 Human Adrenoceptors A pEC50 8.1 9.13 9.72 ChEMBL
β2 ADRB2 Guinea pig Adrenoceptors A pIC50 9.4 9.4 9.4 ChEMBL
β2 ADRB2 Guinea pig Adrenoceptors A pEC50 8.8 9.15 9.5 ChEMBL