GPCRdb

fenoldopam

SMILES	Oc1ccc(cc1)C1CNCCc2c1cc(O)c(c2Cl)O
InChIKey	TVURRHSHRRELCG-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors	4
Hydrogen bond donors	4
Rotatable bonds	1
Molecular weight (Da)	305.1

Drug properties

Molecular type	Small molecule
Endogenous/Surrogate	Surrogate
Approved drug	Yes

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids DrugBank Drug Central PubChem Guide To Pharmacology ChEMBL_compound_ids PubChem PubChem Guide To Pharmacology ChEMBL_compound_ids PubChem GPCRdb
Structure pdb	7CKW 7X2C
Ligand site mutations	D₂ D₅

Bioactivities

Affinity
Potency

Receptor					Activity				Source
GTP	Uniprot	Species	Family	Class	Type	Min	Avg	Max	Database
EP₄	PE2R4	Human	Prostanoid	A	pKi	8.51	8.51	8.51	Guide to Pharmacology
EP₄	PE2R4	Human	Prostanoid	A	pKd	8.75	8.75	8.75	ChEMBL

Receptor					Activity				Source
GTP	Uniprot	Species	Family	Class	Type	Min	Avg	Max	Database
EP₂	PE2R2	Human	Prostanoid	A	pIC50	6.15	6.15	6.15	ChEMBL
EP₄	PE2R4	Human	Prostanoid	A	pIC50	7.42	7.87	8.18	ChEMBL