GPCRdb

fenoldopam

SMILES	Oc1ccc(cc1)C1CNCCc2c1cc(O)c(c2Cl)O
InChIKey	TVURRHSHRRELCG-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors	4
Hydrogen bond donors	4
Rotatable bonds	1
Molecular weight (Da)	305.1

Drug properties

Molecular type	Small molecule
Endogenous/Surrogate	Surrogate
Approved drug	Yes

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids DrugBank Drug Central PubChem Guide To Pharmacology ChEMBL_compound_ids PubChem PubChem Guide To Pharmacology ChEMBL_compound_ids PubChem GPCRdb
Structure pdb	7CKW 7X2C
Ligand site mutations	D₂ D₅

Bioactivities

Affinity
Potency

Receptor					Activity				Source
GTP	Uniprot	Species	Family	Class	Type	Min	Avg	Max	Database
mGlu₁	GRM1	Rat	Metabotropic glutamate	C	pKi	8.82	8.82	8.82	Guide to Pharmacology
mGlu₁	GRM1	Rat	Metabotropic glutamate	C	pKi	9.4	9.4	9.4	ChEMBL

Receptor					Activity				Source
GTP	Uniprot	Species	Family	Class	Type	Min	Avg	Max	Database
mGlu₁	GRM1	Human	Metabotropic glutamate	C	pIC50	8.54	8.54	8.54	Guide to Pharmacology
mGlu₁	GRM1	Human	Metabotropic glutamate	C	pIC50	8.54	8.54	8.54	ChEMBL