5-hydroxytryptamine


SMILES NCCc1c[nH]c2c1cc(O)cc2
InChIKey QZAYGJVTTNCVMB-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 3
Rotatable bonds 2
Molecular weight (Da) 176.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Endogenous
Approved drug Yes

Database connections

Structure pdb 7E32 7XT9 7YS6 7WC4 7E2Y 7XTB 7XT8 7XTA
Ligand site mutations 5-HT1A 5-HT1B 5-HT1D 5-HT2A 5-HT2B 5-HT2C 5-HT4 5-HT5A 5-HT6 5-HT7

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
PAF PTAFR Mouse Platelet-activating factor A pKi 5.8 5.8 5.8 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database