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Construct Crystallization Sequence modifications
PDB UniProt Receptor Rec. Family Class Species Method Mutations Deletions Modifications Insertions PDB Resolution Reference Date
3VW7 PAR1 PAR1 Proteinase-activated A (Rhodopsin) Human in meso/LCP 2 3 0 5 3VW7 2.2 10.1038/NATURE11701 2012-12-12
4ZJC OX1R OX1 Orexin A (Rhodopsin) Human in meso/LCP 1 2 0 4 4ZJC 2.8 10.1038/NSMB.3183 2016-03-09
2J4Y OPSD Rhodopsin Opsins A (Rhodopsin) Bovine vapour diffusion 2 0 0 0 2J4Y 3.4 10.1016/J.JMB.2007.03.007 2007-09-25
2Y02 ADRB1 β1 Adrenoceptors A (Rhodopsin) Common turkey vapour diffusion 8 3 0 1 2Y02 2.6 10.1038/NATURE09746 2011-01-12
3OE8 CXCR4 CXCR4 Chemokine A (Rhodopsin) Human in meso/LCP 1 2 0 7 3OE8 3.1 10.1126/SCIENCE.1194396 2010-10-27
3SN6 ADRB2 β2 Adrenoceptors A (Rhodopsin) Human sponge mesophase 3 2 0 4 3SN6 3.2 10.1038/NATURE10361 2011-07-20
4JKV SMO SMO Frizzled F (Frizzled) Human in meso/LCP 0 2 0 5 4JKV 2.5 10.1038/NATURE12167 2013-04-24
4PHU FFAR1 FFA1 Free fatty acid A (Rhodopsin) Human in meso/LCP 4 1 0 6 4PHU 2.3 10.1038/NATURE13494 2014-07-16
4U15 ACM3 M3 Acetylcholine (muscarinic) A (Rhodopsin) Rat in meso/LCP 0 3 0 4 4U15 2.8 10.1016/J.STR.2014.08.022 2014-11-26
4Z35 LPAR1 LPA1 Lysophospholipid (LPA) A (Rhodopsin) Human in meso/LCP 0 3 0 5 4Z35 2.9 10.1016/J.CELL.2015.06.002 2015-06-03
5L7I SMO SMO Frizzled F (Frizzled) Human in meso/LCP 1 3 0 2 5L7I 3.3 10.1038/NATURE18934 2016-07-20
5NM2 AA2AR A2A Adenosine A (Rhodopsin) Human in meso/LCP 9 3 0 4 5NM2 2.0 10.1038/S41467-017-00630-4 2017-09-27
5UIW CCR5 CCR5 Chemokine A (Rhodopsin) Human in meso/LCP 4 3 0 5 5UIW 2.2 10.1016/J.IMMUNI.2017.05.002 2017-06-28
5XF1 GLR glucagon Glucagon B1 (Secretin) Human in meso/LCP 0 3 0 5 5XF1 3.2 10.1038/NATURE22363 2017-05-24
6D35 Q98SW5 SMO Frizzled F (Frizzled) African clawed frog in meso/LCP 0 3 0 0 6D35 3.9 10.1016/J.CELL.2018.04.029 2018-05-23
5TGZ CNR1 CB1 Cannabinoid A (Rhodopsin) Human in meso/LCP 4 3 0 5 5TGZ 2.8 10.1016/J.CELL.2016.10.004 2016-11-02
3NY9 ADRB2 β2 Adrenoceptors A (Rhodopsin) Human in meso/LCP 4 2 0 3 3NY9 2.8 10.1021/JA105108Q 2010-08-11
5YQZ GLR glucagon Glucagon B1 (Secretin) Human in meso/LCP 1 3 0 5 5YQZ 3.0 10.1038/NATURE25153 2018-01-17
5WF6 AA2AR A2A Adenosine A (Rhodopsin) Human in meso/LCP 1 3 0 4 5WF6 2.9 10.1016/J.STR.2017.12.013 2018-02-21
1GZM OPSD Rhodopsin Opsins A (Rhodopsin) Bovine vapour diffusion 0 0 0 0 1GZM 2.7 10.1016/J.JMB.2004.08.090 2003-11-20
6D32 Q98SW5 SMO Frizzled F (Frizzled) African clawed frog in meso/LCP 0 3 0 0 6D32 3.8 10.1016/J.CELL.2018.04.029 2018-05-23
6D9H AA1R A1 Adenosine A (Rhodopsin) Human Cryo-EM 0 1 0 6 6D9H 3.6 10.1038/S41586-018-0236-6 2018-06-20
5LWE CCR9 CCR9 Chemokine A (Rhodopsin) Human in meso/LCP 10 2 0 2 5LWE 2.8 10.1038/NATURE20606 2016-12-07
6E3Y CALRL calcitonin-like Calcitonin B1 (Secretin) Human N/A 0 1 0 0 6E3Y 3.3 10.1038/S41586-018-0535-Y 2018-09-19
5UVI AA2AR A2A Adenosine A (Rhodopsin) Human in meso/LCP 0 3 0 4 5UVI 3.2 10.1107/S205225251700570X 2017-05-24
4MQT ACM2 M2 Acetylcholine (muscarinic) A (Rhodopsin) Human in meso/LCP 6 1 0 3 4MQT 3.7 10.1038/NATURE12735 2013-11-27
4ZWJ OPSD Rhodopsin Opsins A (Rhodopsin) Human in meso/LCP 4 0 0 7 4ZWJ 3.3 10.1038/NATURE14656 2015-07-29
5UZ7 CALCR CT Calcitonin B1 (Secretin) Human Cryo-EM 0 1 0 5 5UZ7 4.1 10.1038/NATURE22327 2017-05-03
5TZR FFAR1 FFA1 Free fatty acid A (Rhodopsin) Human in meso/LCP 4 1 0 6 5TZR 2.2 10.1038/NSMB.3417 2017-06-07
4BEY OPSD Rhodopsin Opsins A (Rhodopsin) Bovine vapour diffusion 3 0 0 0 4BEY 2.9 10.1038/EMBOR.2013.44 2013-05-08
4X1H OPSD Rhodopsin Opsins A (Rhodopsin) Bovine vapour diffusion 0 0 0 0 4X1H 2.3 10.1016/J.STR.2015.09.015 2015-11-04
5L7D SMO SMO Frizzled F (Frizzled) Human in meso/LCP 1 3 0 2 5L7D 3.2 10.1038/NATURE18934 2016-07-20
3UZA AA2AR A2A Adenosine A (Rhodopsin) Human vapour diffusion 8 1 0 2 3UZA 3.3 10.1021/JM201376W 2012-03-21
4GRV NTR1 NTS1 Neurotensin A (Rhodopsin) Rat in meso/LCP 6 3 0 5 4GRV 2.8 10.1038/NATURE11558 2012-10-17
4UHR AA2AR A2A Adenosine A (Rhodopsin) Human in meso/LCP 5 1 0 2 4UHR 2.6 10.1124/MOL.114.097360 2015-04-08
4IAQ 5HT1B 5-HT1B 5-Hydroxytryptamine A (Rhodopsin) Human in meso/LCP 1 2 0 5 4IAQ 2.8 10.1126/SCIENCE.1232807 2013-03-13
5OM1 AA2AR A2A Adenosine A (Rhodopsin) Human in meso/LCP 9 3 0 3 5OM1 2.1 10.1038/S41598-017-18570-W 2018-01-17
2Z73 OPSD Rhodopsin Opsins A (Rhodopsin) Japanese flying squid vapour diffusion 0 0 0 0 2Z73 2.5 10.1038/NATURE06925 2008-05-13
5DYS OPSD Rhodopsin Opsins A (Rhodopsin) Bovine vapour diffusion 3 0 0 0 5DYS 2.3 10.15252/EMBR.201642671 2016-08-10
4NTJ P2Y12 P2Y12 P2Y A (Rhodopsin) Human in meso/LCP 1 1 0 5 4NTJ 2.6 10.1038/NATURE13083 2014-03-26
6FFH GRM5 mGlu5 Metabotropic glutamate C (Glutamate) Human in meso/LCP 6 2 0 3 6FFH 2.7 10.1021/ACS.JMEDCHEM.7B01722 2018-03-07
3OE0 CXCR4 CXCR4 Chemokine A (Rhodopsin) Human in meso/LCP 2 3 0 6 3OE0 2.9 10.1126/SCIENCE.1194396 2010-10-27
4MBS CCR5 CCR5 Chemokine A (Rhodopsin) Human in meso/LCP 4 2 0 5 4MBS 2.7 10.1126/SCIENCE.1241475 2013-09-11
4DKL OPRM μ Opioid A (Rhodopsin) Mouse in meso/LCP 0 3 0 5 4DKL 2.8 10.1038/NATURE10954 2012-03-21
5VAI G1SGD4 GLP-1 Glucagon B1 (Secretin) Rabbit Cryo-EM 3 2 0 5 5VAI 4.1 10.1038/NATURE22394 2017-05-24
5XRA CNR1 CB1 Cannabinoid A (Rhodopsin) Human in meso/LCP 4 3 0 5 5XRA 2.8 10.1038/NATURE23272 2017-07-12
5IUB AA2AR A2A Adenosine A (Rhodopsin) Human in meso/LCP 9 3 0 4 5IUB 2.1 2016-06-29
4BWB NTR1 NTS1 Neurotensin A (Rhodopsin) Rat vapour diffusion 26 3 0 8 4BWB 3.6 10.1073/PNAS.1317903111 2014-01-29
6C1R C5AR1 C5a1 Complement peptide A (Rhodopsin) Human in meso/LCP 1 2 0 0 6C1R 2.2 10.1038/S41594-018-0067-Z 2018-05-30
5VRA AA2AR A2A Adenosine A (Rhodopsin) Human in meso/LCP 0 3 0 4 5VRA 2.4 10.1038/NPROT.2017.135 2017-12-13
5WB1 Q80KM9 US28 Unclassified A (Rhodopsin) strain AD169 in meso/LCP 0 1 0 9 5WB1 3.5 10.7554/ELIFE.35850 2018-06-13
5D5B ADRB2 β2 Adrenoceptors A (Rhodopsin) Human in meso/LCP 3 2 0 2 5D5B 3.8 10.1107/S2059798315021683 2016-01-13
5X93 EDNRB ETB Endothelin A (Rhodopsin) Human in meso/LCP 8 3 0 7 5X93 2.2 10.1038/NSMB.3450 2017-08-16
4OO9 GRM5 mGlu5 Metabotropic glutamate C (Glutamate) Human in meso/LCP 6 3 0 3 4OO9 2.6 10.1038/NATURE13396 2014-07-02
4EJ4 OPRD δ Opioid A (Rhodopsin) Mouse in meso/LCP 0 3 0 4 4EJ4 3.4 10.1038/NATURE11111 2012-05-16
5WS3 OX2R OX2 Orexin A (Rhodopsin) Human in meso/LCP 1 3 0 4 5WS3 2.3 10.1016/J.STR.2017.11.005 2017-12-13
6CMO OPSD Rhodopsin Opsins A (Rhodopsin) Human Cryo-EM 3 2 0 5 6CMO 4.5 2018-06-20
2RH1 ADRB2 β2 Adrenoceptors A (Rhodopsin) Human in meso/LCP 3 2 0 2 2RH1 2.4 10.1126/SCIENCE.1150577 2007-10-30
5UEN AA1R A1 Adenosine A (Rhodopsin) Human in meso/LCP 1 3 0 8 5UEN 3.2 10.1016/J.CELL.2017.01.042 2017-03-01
3KJ6 ADRB2 β2 Adrenoceptors A (Rhodopsin) Human vapour diffusion 3 2 0 3 3KJ6 3.4 10.1038/NATURE08650 2010-02-16
6M9T PE2R3 EP3 Prostanoid A (Rhodopsin) Human N/A 0 3 0 0 6M9T 2.5 2018-12-05
5DSG ACM4 M4 Acetylcholine (muscarinic) A (Rhodopsin) Human in meso/LCP 0 3 0 3 5DSG 2.6 10.1038/NATURE17188 2016-03-16
4AMJ ADRB1 β1 Adrenoceptors A (Rhodopsin) Common turkey vapour diffusion 8 3 0 1 4AMJ 2.3 10.1016/J.STR.2012.03.014 2012-05-23
4OR2 GRM1 mGlu1 Metabotropic glutamate C (Glutamate) Human in meso/LCP 0 2 0 5 4OR2 2.8 10.1126/SCIENCE.1249489 2014-03-19
5V57 SMO SMO Frizzled F (Frizzled) Human in meso/LCP 0 3 0 6 5V57 3.0 10.1038/NCOMMS15383 2017-05-24
5TE5 OPSD Rhodopsin Opsins A (Rhodopsin) Bovine vapour diffusion 0 0 0 0 5TE5 4.0 10.1073/PNAS.1617446114 2017-03-15
5OLZ AA2AR A2A Adenosine A (Rhodopsin) Human in meso/LCP 9 3 0 3 5OLZ 1.9 10.1038/S41598-017-18570-W 2018-01-17
4BVN ADRB1 β1 Adrenoceptors A (Rhodopsin) Common turkey in meso/LCP 11 3 0 1 4BVN 2.1 10.1371/JOURNAL.PONE.0092727 2014-04-02
5JQH ADRB2 β2 Adrenoceptors A (Rhodopsin) Human in meso/LCP 4 3 0 4 5JQH 3.2 10.1038/NATURE18636 2016-07-13
5VBL APJ apelin Apelin A (Rhodopsin) Human in meso/LCP 5 3 0 5 5VBL 2.6 10.1016/J.STR.2017.04.008 2017-05-31
3RZE HRH1 H1 Histamine A (Rhodopsin) Human in meso/LCP 0 2 0 4 3RZE 3.1 10.1038/NATURE10236 2011-06-15
2R4S ADRB2 β2 Adrenoceptors A (Rhodopsin) Human vapour diffusion 1 2 0 3 2R4S 3.4 10.1038/NATURE06325 2007-11-06
5OLO AA2AR A2A Adenosine A (Rhodopsin) Human in meso/LCP 9 3 0 4 5OLO 3.1 10.1038/S41598-017-18570-W 2018-01-17
5IU8 AA2AR A2A Adenosine A (Rhodopsin) Human in meso/LCP 9 3 0 4 5IU8 2.0 10.1021/ACS.JMEDCHEM.6B00653 2016-06-29
6C1Q C5AR1 C5a1 Complement peptide A (Rhodopsin) Human in meso/LCP 1 2 0 0 6C1Q 2.9 10.1038/S41594-018-0067-Z 2018-05-30
5N2S AA1R A1 Adenosine A (Rhodopsin) Human in meso/LCP 8 2 0 3 5N2S 3.3 10.1016/J.STR.2017.06.012 2017-07-26
5WF5 AA2AR A2A Adenosine A (Rhodopsin) Human in meso/LCP 1 3 0 4 5WF5 2.6 10.1016/J.STR.2017.12.013 2018-02-21
3OE9 CXCR4 CXCR4 Chemokine A (Rhodopsin) Human in meso/LCP 2 3 0 6 3OE9 3.1 10.1126/SCIENCE.1194396 2010-10-27
3P0G ADRB2 β2 Adrenoceptors A (Rhodopsin) Human in meso/LCP 3 2 0 3 3P0G 3.5 10.1038/NATURE09648 2011-01-19
3PBL DRD3 D3 Dopamine A (Rhodopsin) Human in meso/LCP 1 2 0 5 3PBL 2.9 10.1126/SCIENCE.1197410 2010-11-03
3V2Y S1PR1 S1P1 Lysophospholipid (S1P) A (Rhodopsin) Human in meso/LCP 2 4 0 5 3V2Y 2.8 10.1126/SCIENCE.1215904 2012-02-15
5DHG OPRX NOP Opioid A (Rhodopsin) Human in meso/LCP 0 2 0 5 5DHG 3.0 10.1016/J.STR.2015.07.024 2015-10-21
5MZP AA2AR A2A Adenosine A (Rhodopsin) Human in meso/LCP 9 3 0 4 5MZP 2.1 10.1016/J.STR.2017.06.012 2017-07-26
5OLH AA2AR A2A Adenosine A (Rhodopsin) Human in meso/LCP 9 3 0 3 5OLH 2.6 10.1038/S41598-017-18570-W 2018-01-17
5T04 NTR1 NTS1 Neurotensin A (Rhodopsin) Rat in meso/LCP 4 3 0 5 5T04 3.3 10.1038/SREP38564 2016-12-21
5ZKC ACM2 M2 Acetylcholine (muscarinic) A (Rhodopsin) Human N/A 0 2 0 0 5ZKC 2.3 10.1038/S41589-018-0152-Y 2018-11-21
6B3J GLP1R GLP-1 Glucagon B1 (Secretin) Human Cryo-EM 0 1 0 5 6B3J 3.3 10.1038/NATURE25773 2018-02-21
6CM4 DRD2 D2 Dopamine A (Rhodopsin) Human in meso/LCP 3 2 0 5 6CM4 2.9 10.1038/NATURE25758 2018-03-14
6DRX 5HT2B 5-HT2B 5-Hydroxytryptamine A (Rhodopsin) Human N/A 1 3 0 0 6DRX 3.1 10.1038/S41594-018-0116-7 2018-08-29
4BEZ OPSD Rhodopsin Opsins A (Rhodopsin) Bovine vapour diffusion 3 0 0 0 4BEZ 3.3 10.1038/EMBOR.2013.44 2013-04-24
3NY8 ADRB2 β2 Adrenoceptors A (Rhodopsin) Human in meso/LCP 4 2 0 3 3NY8 2.8 10.1021/JA105108Q 2010-08-11
5YWY PE2R4 EP4 Prostanoid A (Rhodopsin) Human N/A 0 3 0 0 5YWY 3.2 10.1038/S41589-018-0131-3 2018-12-05
6FK6 OPSD Rhodopsin Opsins A (Rhodopsin) Bovine vapour diffusion 2 1 0 0 6FK6 2.4 10.1073/PNAS.1718084115 2018-04-04
4LDE ADRB2 β2 Adrenoceptors A (Rhodopsin) Human in meso/LCP 4 3 0 3 4LDE 2.8 10.1038/NATURE12572 2013-09-25
5WB2 Q80KM9 US28 Unclassified A (Rhodopsin) strain AD169 in meso/LCP 0 1 0 9 5WB2 3.5 2018-06-13
5XEZ GLR glucagon Glucagon B1 (Secretin) Human in meso/LCP 0 3 0 5 5XEZ 3.0 10.1038/NATURE22363 2017-05-24
6H7J ADRB1 β1 Adrenoceptors A (Rhodopsin) Common turkey N/A 6 3 0 0 6H7J 2.8 10.1101/436212 2018-10-17
5YC8 ACM2 M2 Acetylcholine (muscarinic) A (Rhodopsin) Human N/A 0 2 0 0 5YC8 2.5 10.1038/S41589-018-0152-Y 2018-11-21
5ZKP PTAFR PAF Platelet-activating factor A (Rhodopsin) Human N/A 5 3 0 0 5ZKP 2.8 10.1038/S41594-018-0068-Y 2018-06-20
4ZJ8 OX1R OX1 Orexin A (Rhodopsin) Human in meso/LCP 1 2 0 4 4ZJ8 2.8 10.1038/NSMB.3183 2016-03-09
4MQS ACM2 M2 Acetylcholine (muscarinic) A (Rhodopsin) Human in meso/LCP 6 1 0 3 4MQS 3.5 10.1038/NATURE12735 2013-11-27
4RWD OPRD δ Opioid A (Rhodopsin) Human in meso/LCP 0 2 0 5 4RWD 2.7 10.1038/NSMB.2965 2015-01-14
4K5Y CRFR1 CRF1 Corticotropin-releasing factor B1 (Secretin) Human in meso/LCP 11 3 0 3 4K5Y 3.0 10.1038/NATURE12357 2013-07-17
2Y04 ADRB1 β1 Adrenoceptors A (Rhodopsin) Common turkey vapour diffusion 8 3 0 1 2Y04 3.1 10.1038/NATURE09746 2011-01-12
3VGA AA2AR A2A Adenosine A (Rhodopsin) Human vapour diffusion 1 1 0 3 3VGA 3.1 10.1038/NATURE10750 2012-02-01
1L9H OPSD Rhodopsin Opsins A (Rhodopsin) Bovine vapour diffusion 0 0 0 0 1L9H 2.6 10.1073/PNAS.082666399 2002-05-15
5IU4 AA2AR A2A Adenosine A (Rhodopsin) Human in meso/LCP 9 3 0 4 5IU4 1.7 10.1021/ACS.JMEDCHEM.6B00653 2016-06-29
6HLO NK1R NK1 Tachykinin A (Rhodopsin) Human N/A 0 2 0 0 6HLO 2.4 10.1038/S41467-018-07939-8 2019-01-16
6D26 PD2R2 DP2 Prostanoid A (Rhodopsin) Human N/A 0 2 0 0 6D26 2.8 2018-10-03
1HZX OPSD Rhodopsin Opsins A (Rhodopsin) Bovine vapour diffusion 0 0 0 0 1HZX 2.8 10.1021/BI0155091 2001-07-04
6GPX CCR2 CCR2 Chemokine A (Rhodopsin) Human N/A 0 3 0 0 6GPX 2.7 10.1016/J.STR.2018.10.027 2019-01-02
5N2R AA2AR A2A Adenosine A (Rhodopsin) Human in meso/LCP 9 3 0 4 5N2R 2.8 10.1016/J.STR.2017.06.012 2017-07-26
6IGL EDNRB ETB Endothelin A (Rhodopsin) Human N/A 0 3 0 0 6IGL 2.7 10.1038/S41467-018-07094-0 2018-11-21
5ZKQ PTAFR PAF Platelet-activating factor A (Rhodopsin) Human N/A 5 3 0 0 5ZKQ 2.9 10.1038/S41594-018-0068-Y 2018-06-20
6H7N ADRB1 β1 Adrenoceptors A (Rhodopsin) Common turkey N/A 6 3 0 0 6H7N 2.5 10.1101/436212 2018-10-17
5WIU DRD4 D4 Dopamine A (Rhodopsin) Human in meso/LCP 0 1 0 5 5WIU 2.0 10.1126/SCIENCE.AAN5468 2017-10-18
3EML AA2AR A2A Adenosine A (Rhodopsin) Human in meso/LCP 0 3 0 5 3EML 2.6 10.1126/SCIENCE.1164772 2008-10-14
2G87 OPSD Rhodopsin Opsins A (Rhodopsin) Bovine vapour diffusion 0 0 0 0 2G87 2.6 10.1002/ANIE.200600595 2006-09-02
3REY AA2AR A2A Adenosine A (Rhodopsin) Human vapour diffusion 8 1 0 1 3REY 3.3 10.1016/J.STR.2011.06.014 2011-09-07
6IIV TA2R TP Prostanoid A (Rhodopsin) Human N/A 0 3 0 0 6IIV 3.0 10.1038/S41589-018-0170-9 2018-12-19
5CGD GRM5 mGlu5 Metabotropic glutamate C (Glutamate) Human in meso/LCP 6 2 0 3 5CGD 2.6 10.1021/ACS.JMEDCHEM.5B00892 2015-08-12
6MXT ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 1 3 0 0 6MXT 3.0 10.1038/S41589-018-0145-X 2018-11-14
3UON ACM2 M2 Acetylcholine (muscarinic) A (Rhodopsin) Human in meso/LCP 4 1 0 1 3UON 3.0 10.1038/NATURE10753 2012-02-01
4WW3 OPSD Rhodopsin Opsins A (Rhodopsin) Japanese flying squid vapour diffusion 0 2 0 1 4WW3 2.8 10.1371/JOURNAL.PONE.0126970 2015-06-17
5MZJ AA2AR A2A Adenosine A (Rhodopsin) Human in meso/LCP 9 3 0 4 5MZJ 2.0 10.1016/J.STR.2017.06.012 2017-07-26
4J4Q OPSD Rhodopsin Opsins A (Rhodopsin) Bovine vapour diffusion 0 0 0 0 4J4Q 2.7 10.1002/ANIE.201302374 2013-10-30
4ZUD AGTR1 AT1 Angiotensin A (Rhodopsin) Human in meso/LCP 0 3 0 5 4ZUD 2.8 10.1074/JBC.M115.689000 2015-10-07
5TZY FFAR1 FFA1 Free fatty acid A (Rhodopsin) Human in meso/LCP 3 1 0 6 5TZY 3.2 10.1038/NSMB.3417 2017-06-07
4EIY AA2AR A2A Adenosine A (Rhodopsin) Human in meso/LCP 0 3 0 4 4EIY 1.8 10.1126/SCIENCE.1219218 2012-07-25
6FK7 OPSD Rhodopsin Opsins A (Rhodopsin) Bovine vapour diffusion 2 0 0 0 6FK7 2.6 10.1073/PNAS.1718084115 2018-04-04
4XES NTR1 NTS1 Neurotensin A (Rhodopsin) Rat in meso/LCP 4 3 0 5 4XES 2.6 10.1038/NCOMMS8895 2015-07-29
3UZC AA2AR A2A Adenosine A (Rhodopsin) Human vapour diffusion 8 1 0 2 3UZC 3.3 10.1021/JM201376W 2012-03-21
6DDF OPRM μ Opioid A (Rhodopsin) Mouse Cryo-EM 0 2 0 4 6DDF 3.5 10.1038/S41586-018-0219-7 2018-06-13
5V56 SMO SMO Frizzled F (Frizzled) Human in meso/LCP 1 3 0 6 5V56 2.9 10.1038/NCOMMS15383 2017-05-24
5CXV ACM1 M1 Acetylcholine (muscarinic) A (Rhodopsin) Human in meso/LCP 3 2 0 4 5CXV 2.7 10.1038/NATURE17188 2016-03-09
4AMI ADRB1 β1 Adrenoceptors A (Rhodopsin) Common turkey vapour diffusion 8 3 0 1 4AMI 3.2 10.1016/J.STR.2012.03.014 2012-05-23
4N6H OPRD δ Opioid A (Rhodopsin) Human in meso/LCP 1 2 0 5 4N6H 1.8 10.1038/NATURE12944 2013-12-25
5F8U ADRB1 β1 Adrenoceptors A (Rhodopsin) Common turkey vapour diffusion 8 4 0 2 5F8U 3.4 10.1038/NSMB.3130 2015-12-23
4PY0 P2Y12 P2Y12 P2Y A (Rhodopsin) Human in meso/LCP 1 1 0 5 4PY0 3.1 10.1038/NATURE13288 2014-04-30
5O9H C5AR1 C5a1 Complement peptide A (Rhodopsin) Human in meso/LCP 11 2 0 1 5O9H 2.7 10.1038/NATURE25025 2018-01-10
3PQR OPSD Rhodopsin Opsins A (Rhodopsin) Bovine vapour diffusion 0 0 0 0 3PQR 2.9 10.1038/NATURE09789 2011-03-09
5ZBH NPY1R Y1 Neuropeptide Y A (Rhodopsin) Human N/A 1 3 0 0 5ZBH 3.0 10.1038/S41586-018-0046-X 2018-04-25
5C1M OPRM μ Opioid A (Rhodopsin) Mouse in meso/LCP 0 2 0 4 5C1M 2.1 10.1038/NATURE14886 2015-08-05
3OAX OPSD Rhodopsin Opsins A (Rhodopsin) Bovine vapour diffusion 0 0 0 0 3OAX 2.6 10.1016/J.BPJ.2010.08.003 2011-01-19
6AKX CCR5 CCR5 Chemokine A (Rhodopsin) Human N/A 4 3 0 0 6AKX 2.8 10.1021/ACS.JMEDCHEM.8B01077 2018-10-24
2VT4 ADRB1 β1 Adrenoceptors A (Rhodopsin) Common turkey vapour diffusion 8 4 0 1 2VT4 2.7 10.1038/NATURE07101 2008-06-24
5X33 Q9WTK1 BLT1 Leukotriene A (Rhodopsin) Guinea pig in meso/LCP 4 1 0 5 5X33 3.7 10.1038/NCHEMBIO.2547 2018-01-03
6FJ3 PTH1R PTH1 Parathyroid hormone B1 (Secretin) Human N/A 0 4 0 0 6FJ3 2.5 10.1038/S41594-018-0151-4 2018-11-21
6B73 OPRK κ Opioid A (Rhodopsin) Human in meso/LCP 1 2 0 6 6B73 3.1 10.1016/J.CELL.2017.12.011 2018-01-17
5G53 AA2AR A2A Adenosine A (Rhodopsin) Human vapour diffusion 1 1 0 2 5G53 3.4 10.1038/NATURE18966 2016-08-03
6HLP NK1R NK1 Tachykinin A (Rhodopsin) Human N/A 0 2 0 0 6HLP 2.2 10.1038/S41467-018-07939-8 2019-01-16
2YCX ADRB1 β1 Adrenoceptors A (Rhodopsin) Common turkey vapour diffusion 8 4 0 1 2YCX 3.3 10.1073/PNAS.1100185108 2011-06-01
3PDS ADRB2 β2 Adrenoceptors A (Rhodopsin) Human in meso/LCP 3 3 0 3 3PDS 3.5 10.1038/NATURE09665 2011-01-12
6HLL NK1R NK1 Tachykinin A (Rhodopsin) Human N/A 0 2 0 0 6HLL 3.3 10.1038/S41467-018-07939-8 2019-01-16
2PED OPSD Rhodopsin Opsins A (Rhodopsin) Bovine vapour diffusion 0 0 0 0 2PED 3.0 10.1529/BIOPHYSJ.107.108225 2007-10-30
5JTB AA2AR A2A Adenosine A (Rhodopsin) Human in meso/LCP 0 3 0 4 5JTB 2.8 10.1126/SCIADV.1602952 2017-05-31
6AK3 PE2R3 EP3 Prostanoid A (Rhodopsin) Human N/A 0 2 0 0 6AK3 2.9 10.1038/S41589-018-0131-3 2018-12-05
5NJ6 PAR2 PAR2 Proteinase-activated A (Rhodopsin) Human in meso/LCP 10 3 0 2 5NJ6 4.0 10.1038/NATURE22309 2017-05-03
3C9M OPSD Rhodopsin Opsins A (Rhodopsin) Bovine NA 2 0 0 0 3C9M 3.4 10.1107/S0907444908017162 2008-08-05
3PWH AA2AR A2A Adenosine A (Rhodopsin) Human vapour diffusion 8 1 0 2 3PWH 3.3 10.1016/J.STR.2011.06.014 2011-09-07
4LDO ADRB2 β2 Adrenoceptors A (Rhodopsin) Human in meso/LCP 4 3 0 3 4LDO 3.2 10.1038/NATURE12572 2013-09-25
4QIN SMO SMO Frizzled F (Frizzled) Human in meso/LCP 0 3 0 5 4QIN 2.6 10.1038/NCOMMS5355 2014-07-23
4U16 ACM3 M3 Acetylcholine (muscarinic) A (Rhodopsin) Rat sponge mesophase 0 3 0 4 4U16 3.7 10.1016/J.STR.2014.08.022 2014-11-26
4XNV P2RY1 P2Y1 P2Y A (Rhodopsin) Human in meso/LCP 1 2 0 5 4XNV 2.2 10.1038/NATURE14287 2015-04-01
4XT1 US28 US28 Unclassified A (Rhodopsin) strain AD169 in meso/LCP 0 2 0 1 4XT1 2.9 10.1126/SCIENCE.AAA5026 2015-03-04
5IU7 AA2AR A2A Adenosine A (Rhodopsin) Human in meso/LCP 9 3 0 4 5IU7 1.9 10.1021/ACS.JMEDCHEM.6B00653 2016-06-29
5OM4 AA2AR A2A Adenosine A (Rhodopsin) Human in meso/LCP 9 3 0 3 5OM4 2.0 10.1038/S41598-017-18570-W 2018-01-17
5UNH AGTR2 AT2 Angiotensin A (Rhodopsin) Human in meso/LCP 0 2 0 6 5UNH 2.9 10.1038/NATURE22035 2017-04-05
5WIV DRD4 D4 Dopamine A (Rhodopsin) Human in meso/LCP 0 1 0 5 5WIV 2.1 10.1126/SCIENCE.AAN5468 2017-10-18
5WKT OPSD Rhodopsin Opsins A (Rhodopsin) Bovine vapour diffusion 0 0 0 0 5WKT 3.2 10.1038/NPROT.2017.135 2017-12-13
6H7L ADRB1 β1 Adrenoceptors A (Rhodopsin) Common turkey N/A 6 3 0 0 6H7L 2.7 10.1101/436212 2018-10-17
6H7M ADRB1 β1 Adrenoceptors A (Rhodopsin) Common turkey N/A 6 3 0 0 6H7M 2.8 10.1101/436212 2018-10-17
6MET CCR5 CCR5 Chemokine A (Rhodopsin) Human N/A 0 1 0 0 6MET 4.5 10.1038/S41586-018-0804-9 2018-12-12
4IAR 5HT1B 5-HT1B 5-Hydroxytryptamine A (Rhodopsin) Human in meso/LCP 1 2 0 5 4IAR 2.7 10.1126/SCIENCE.1232807 2013-03-13
6FKA OPSD Rhodopsin Opsins A (Rhodopsin) Bovine vapour diffusion 2 0 0 0 6FKA 2.7 10.1073/PNAS.1718084115 2018-04-04
6MEO CCR5 CCR5 Chemokine A (Rhodopsin) Human N/A 0 1 0 0 6MEO 3.9 10.1038/S41586-018-0804-9 2018-12-12
6FK8 OPSD Rhodopsin Opsins A (Rhodopsin) Bovine vapour diffusion 2 0 0 0 6FK8 2.9 10.1073/PNAS.1718084115 2018-04-04
3ZPR ADRB1 β1 Adrenoceptors A (Rhodopsin) Common turkey vapour diffusion 8 3 0 1 3ZPR 2.7 10.1021/JM400140Q 2013-04-03
6FUF OPSD Rhodopsin Opsins A (Rhodopsin) Bovine N/A 0 2 0 0 6FUF 3.1 10.1126/SCIADV.AAT7052 2018-10-03
5XPR EDNRB ETB Endothelin A (Rhodopsin) Human in meso/LCP 7 3 0 7 5XPR 3.6 10.1038/NSMB.3450 2017-08-16
6BQG 5HT2C 5-HT2C 5-Hydroxytryptamine A (Rhodopsin) Human in meso/LCP 1 3 0 5 6BQG 3.0 10.1016/J.CELL.2018.01.001 2018-02-14
2YDV AA2AR A2A Adenosine A (Rhodopsin) Human vapour diffusion 5 1 0 2 2YDV 2.6 10.1038/NATURE10136 2011-05-18
5ZK8 ACM2 M2 Acetylcholine (muscarinic) A (Rhodopsin) Human N/A 0 2 0 0 5ZK8 3.0 10.1038/S41589-018-0152-Y 2018-11-21
5A8E ADRB1 β1 Adrenoceptors A (Rhodopsin) Common turkey in meso/LCP 11 3 0 1 5A8E 2.4 10.1124/MOL.115.101030 2015-09-30
6FFI GRM5 mGlu5 Metabotropic glutamate C (Glutamate) Human in meso/LCP 6 3 0 3 6FFI 2.2 10.1021/ACS.JMEDCHEM.7B01722 2018-03-07
6IGK EDNRB ETB Endothelin A (Rhodopsin) Human N/A 0 3 0 0 6IGK 2.0 10.1038/S41467-018-07094-0 2018-11-21
5DGY OPSD Rhodopsin Opsins A (Rhodopsin) Human in meso/LCP 4 0 0 7 5DGY 7.7 10.1038/SDATA.2016.21 2016-03-23
5DHH OPRX NOP Opioid A (Rhodopsin) Human in meso/LCP 0 2 0 5 5DHH 3.0 10.1016/J.STR.2015.07.024 2015-10-21
2YCW ADRB1 β1 Adrenoceptors A (Rhodopsin) Common turkey vapour diffusion 8 4 0 1 2YCW 3.0 10.1073/PNAS.1100185108 2011-06-01
2YCZ ADRB1 β1 Adrenoceptors A (Rhodopsin) Common turkey vapour diffusion 8 4 0 1 2YCZ 3.7 10.1073/PNAS.1100185108 2011-06-01
4QIM SMO SMO Frizzled F (Frizzled) Human in meso/LCP 0 3 0 5 4QIM 2.6 10.1038/NCOMMS5355 2014-07-23
6GPS CCR2 CCR2 Chemokine A (Rhodopsin) Human N/A 0 2 0 0 6GPS 3.3 10.1016/J.STR.2018.10.027 2019-01-02
4EA3 OPRX NOP Opioid A (Rhodopsin) Human in meso/LCP 0 2 0 5 4EA3 3.0 10.1038/NATURE11085 2012-04-25
5CGC GRM5 mGlu5 Metabotropic glutamate C (Glutamate) Human in meso/LCP 6 2 0 3 5CGC 3.1 10.1021/ACS.JMEDCHEM.5B00892 2015-08-12
6DRY 5HT2B 5-HT2B 5-Hydroxytryptamine A (Rhodopsin) Human N/A 1 3 0 0 6DRY 2.9 10.1038/S41594-018-0116-7 2018-08-29
1F88 OPSD Rhodopsin Opsins A (Rhodopsin) Bovine vapour diffusion 0 0 0 0 1F88 2.8 10.1126/SCIENCE.289.5480.739 2000-08-04
6D27 PD2R2 DP2 Prostanoid A (Rhodopsin) Human N/A 0 2 0 0 6D27 2.7 2018-10-03
5ZKB ACM2 M2 Acetylcholine (muscarinic) A (Rhodopsin) Human N/A 0 2 0 0 5ZKB 3.0 10.1038/S41589-018-0152-Y 2018-11-21
5X7D ADRB2 β2 Adrenoceptors A (Rhodopsin) Human in meso/LCP 3 2 0 2 5X7D 2.7 10.1038/NATURE23652 2017-08-16
5W0P OPSD Rhodopsin Opsins A (Rhodopsin) Human in meso/LCP 6 0 0 7 5W0P 3.0 10.1016/J.CELL.2017.07.002 2017-08-09
4DAJ ACM3 M3 Acetylcholine (muscarinic) A (Rhodopsin) Rat in meso/LCP 0 2 0 4 4DAJ 3.4 10.1038/NATURE10867 2012-02-22
5TVN 5HT2B 5-HT2B 5-Hydroxytryptamine A (Rhodopsin) Human in meso/LCP 1 3 0 5 5TVN 2.9 10.1016/J.CELL.2016.12.033 2017-02-01
4A4M OPSD Rhodopsin Opsins A (Rhodopsin) Bovine vapour diffusion 3 0 0 0 4A4M 3.3 10.1073/PNAS.1114089108 2012-01-25
6FKB OPSD Rhodopsin Opsins A (Rhodopsin) Bovine vapour diffusion 2 1 0 0 6FKB 3.0 10.1073/PNAS.1718084115 2018-04-04
3D4S ADRB2 β2 Adrenoceptors A (Rhodopsin) Human in meso/LCP 4 2 0 3 3D4S 2.8 10.1016/J.STR.2008.05.001 2008-06-17
4XEE NTR1 NTS1 Neurotensin A (Rhodopsin) Rat in meso/LCP 3 3 0 5 4XEE 2.9 10.1038/NCOMMS8895 2015-07-29
5UNF AGTR2 AT2 Angiotensin A (Rhodopsin) Human in meso/LCP 0 2 0 6 5UNF 2.8 10.1038/NATURE22035 2017-04-05
3CAP OPSD Rhodopsin Opsins A (Rhodopsin) Bovine vapour diffusion 0 0 0 0 3CAP 2.9 10.1038/NATURE07063 2008-06-24
4O9R SMO SMO Frizzled F (Frizzled) Human in meso/LCP 0 3 0 1 4O9R 3.2 10.1038/NCOMMS4309 2014-03-05
4UG2 AA2AR A2A Adenosine A (Rhodopsin) Human in meso/LCP 5 1 0 3 4UG2 2.6 10.1124/MOL.114.097360 2015-04-08
6IIU TA2R TP Prostanoid A (Rhodopsin) Human N/A 0 3 0 0 6IIU 2.5 10.1038/S41589-018-0170-9 2018-12-19
5ZBQ NPY1R Y1 Neuropeptide Y A (Rhodopsin) Human in meso/LCP 1 2 0 5 5ZBQ 2.7 10.1038/S41586-018-0046-X 2018-04-25
6DRZ 5HT2B 5-HT2B 5-Hydroxytryptamine A (Rhodopsin) Human N/A 1 3 0 0 6DRZ 3.1 10.1038/S41594-018-0116-7 2018-08-29
5K2B AA2AR A2A Adenosine A (Rhodopsin) Human in meso/LCP 0 3 0 4 5K2B 2.5 10.1126/SCIADV.1600292 2016-09-21
5NLX AA2AR A2A Adenosine A (Rhodopsin) Human in meso/LCP 9 3 0 4 5NLX 2.1 10.1038/S41467-017-00630-4 2017-09-27
2ZIY OPSD Rhodopsin Opsins A (Rhodopsin) Japanese flying squid vapour diffusion 1 2 0 0 2ZIY 3.7 10.1074/JBC.C800040200 2008-05-06
4YAY AGTR1 AT1 Angiotensin A (Rhodopsin) Human in meso/LCP 0 3 0 5 4YAY 2.9 10.1016/J.CELL.2015.04.011 2015-04-22
5KW2 FFAR1 FFA1 Free fatty acid A (Rhodopsin) Human in meso/LCP 4 1 0 3 5KW2 2.8 10.1038/S41467-017-01240-W 2018-05-02
5GLI EDNRB ETB Endothelin A (Rhodopsin) Human in meso/LCP 0 3 0 7 5GLI 2.5 10.1038/NATURE19319 2016-09-07
4GPO ADRB1 β1 Adrenoceptors A (Rhodopsin) Common turkey vapour diffusion 8 4 0 2 4GPO 3.5 10.1038/NSMB.2504 2013-02-27
6AKY CCR5 CCR5 Chemokine A (Rhodopsin) Human N/A 4 3 0 0 6AKY 2.8 10.1021/ACS.JMEDCHEM.8B01077 2018-10-24
4XT3 US28 US28 Unclassified A (Rhodopsin) strain AD169 in meso/LCP 0 2 0 1 4XT3 3.8 10.1126/SCIENCE.AAA5026 2015-03-04
6E59 NK1R NK1 Tachykinin A (Rhodopsin) Human N/A 0 2 0 0 6E59 3.4 10.1073/PNAS.1812717115 2018-12-12
4GBR ADRB2 β2 Adrenoceptors A (Rhodopsin) Human in meso/LCP 3 3 0 5 4GBR 4.0 10.1371/JOURNAL.PONE.0046039 2012-10-24
6H7O ADRB1 β1 Adrenoceptors A (Rhodopsin) Common turkey N/A 6 3 0 0 6H7O 2.8 10.1101/436212 2018-10-17
2X72 OPSD Rhodopsin Opsins A (Rhodopsin) Bovine vapour diffusion 3 0 0 0 2X72 3.0 10.1038/NATURE09795 2011-03-16
5XJM AGTR2 AT2 Angiotensin A (Rhodopsin) Human N/A 0 3 0 0 5XJM 3.2 10.1038/S41594-018-0079-8 2018-07-11
6GDG AA2AR A2A Adenosine A (Rhodopsin) Human Cryo-EM 1 2 0 5 6GDG 4.1 10.7554/ELIFE.35946 2018-05-16
6DS0 5HT2B 5-HT2B 5-Hydroxytryptamine A (Rhodopsin) Human N/A 1 3 0 0 6DS0 3.2 10.1038/S41594-018-0116-7 2018-08-29
3RFM AA2AR A2A Adenosine A (Rhodopsin) Human vapour diffusion 8 1 0 2 3RFM 3.6 10.1016/J.STR.2011.06.014 2011-09-07
5ZK3 ACM2 M2 Acetylcholine (muscarinic) A (Rhodopsin) Human N/A 0 2 0 0 5ZK3 2.6 10.1038/S41589-018-0152-Y 2018-11-21
6DDE OPRM μ Opioid A (Rhodopsin) Mouse Cryo-EM 0 2 0 4 6DDE 3.5 10.1038/S41586-018-0219-7 2018-06-13
5OLV AA2AR A2A Adenosine A (Rhodopsin) Human in meso/LCP 9 3 0 3 5OLV 2.0 10.1038/S41598-017-18570-W 2018-01-17
5V54 5HT1B 5-HT1B 5-Hydroxytryptamine A (Rhodopsin) Human in meso/LCP 1 2 0 5 5V54 3.9 2018-02-07
5GLH EDNRB ETB Endothelin A (Rhodopsin) Human in meso/LCP 0 3 0 7 5GLH 2.8 10.1038/NATURE19319 2016-09-07
5D6L ADRB2 β2 Adrenoceptors A (Rhodopsin) Human in meso/LCP 3 2 0 2 5D6L 3.2 10.1038/NPROT.2017.057 2016-08-17
2I35 OPSD Rhodopsin Opsins A (Rhodopsin) Bovine vapour diffusion 0 0 0 0 2I35 3.8 10.1073/PNAS.0608022103 2006-10-17
5NDD PAR2 PAR2 Proteinase-activated A (Rhodopsin) Human in meso/LCP 10 3 0 4 5NDD 2.8 10.1038/NATURE22309 2017-05-03
5NDZ PAR2 PAR2 Proteinase-activated A (Rhodopsin) Human in meso/LCP 10 3 0 4 5NDZ 3.6 10.1038/NATURE22309 2017-05-03
4IB4 5HT2B 5-HT2B 5-Hydroxytryptamine A (Rhodopsin) Human in meso/LCP 1 3 0 5 4IB4 2.7 10.1126/SCIENCE.1232808 2013-03-13
1U19 OPSD Rhodopsin Opsins A (Rhodopsin) Bovine vapour diffusion 0 0 0 0 1U19 2.2 10.1016/J.JMB.2004.07.044 2004-10-12
2Y00 ADRB1 β1 Adrenoceptors A (Rhodopsin) Common turkey vapour diffusion 8 3 0 1 2Y00 2.5 10.1038/NATURE09746 2011-01-12
3C9L OPSD Rhodopsin Opsins A (Rhodopsin) Bovine NA 0 0 0 0 3C9L 2.7 10.1107/S0907444908017162 2008-08-05
3PXO OPSD Rhodopsin Opsins A (Rhodopsin) Bovine vapour diffusion 0 0 0 0 3PXO 3.0 10.1038/NATURE09789 2011-03-09
3VG9 AA2AR A2A Adenosine A (Rhodopsin) Human vapour diffusion 1 1 0 3 3VG9 2.7 10.1038/NATURE10750 2012-02-01
4L6R GLR glucagon Glucagon B1 (Secretin) Human in meso/LCP 0 2 0 5 4L6R 3.3 10.1038/NATURE12393 2013-07-24
4RWS CXCR4 CXCR4 Chemokine A (Rhodopsin) Human in meso/LCP 3 3 0 5 4RWS 3.1 10.1126/SCIENCE.1261064 2015-02-11
4Z36 LPAR1 LPA1 Lysophospholipid (LPA) A (Rhodopsin) Human in meso/LCP 2 3 0 5 4Z36 2.9 10.1016/J.CELL.2015.06.002 2015-06-03
5K2A AA2AR A2A Adenosine A (Rhodopsin) Human in meso/LCP 0 3 0 4 5K2A 2.5 10.1126/SCIADV.1600292 2016-09-21
5TUD 5HT2B 5-HT2B 5-Hydroxytryptamine A (Rhodopsin) Human in meso/LCP 1 3 0 5 5TUD 3.0 10.1073/PNAS.1700891114 2017-07-26
6AQF AA2AR A2A Adenosine A (Rhodopsin) Human in meso/LCP 0 3 0 3 6AQF 2.5 10.1016/J.CELL.2017.12.004 2018-01-10
6FKC OPSD Rhodopsin Opsins A (Rhodopsin) Bovine vapour diffusion 2 0 0 0 6FKC 2.5 10.1073/PNAS.1718084115 2018-04-04
6G79 5HT1B 5-HT1B 5-Hydroxytryptamine A (Rhodopsin) Human Cryo-EM 1 1 0 2 6G79 3.8 10.1038/S41586-018-0241-9 2018-06-20
3ZPQ ADRB1 β1 Adrenoceptors A (Rhodopsin) Common turkey vapour diffusion 8 3 0 1 3ZPQ 2.8 10.1021/JM400140Q 2013-04-03
3AYN OPSD Rhodopsin Opsins A (Rhodopsin) Japanese flying squid vapour diffusion 0 0 0 0 3AYN 2.7 10.1016/J.JMB.2011.08.044 2011-08-17
3ODU CXCR4 CXCR4 Chemokine A (Rhodopsin) Human in meso/LCP 1 2 0 7 3ODU 2.5 10.1126/SCIENCE.1194396 2010-10-27
5U09 CNR1 CB1 Cannabinoid A (Rhodopsin) Human in meso/LCP 1 3 0 5 5U09 2.6 10.1038/NATURE20613 2016-12-07
6BQH 5HT2C 5-HT2C 5-Hydroxytryptamine A (Rhodopsin) Human in meso/LCP 1 3 0 5 6BQH 2.7 10.1016/J.CELL.2018.01.001 2018-02-14
5YHL PE2R4 EP4 Prostanoid A (Rhodopsin) Human N/A 0 3 0 0 5YHL 4.2 10.1038/S41589-018-0131-3 2018-12-05
3NYA ADRB2 β2 Adrenoceptors A (Rhodopsin) Human in meso/LCP 4 2 0 3 3NYA 3.2 10.1021/JA105108Q 2010-08-11
2I36 OPSD Rhodopsin Opsins A (Rhodopsin) Bovine vapour diffusion 0 0 0 0 2I36 4.1 10.1073/PNAS.0608022103 2006-10-17
4Z34 LPAR1 LPA1 Lysophospholipid (LPA) A (Rhodopsin) Human in meso/LCP 0 3 0 5 4Z34 3.0 10.1016/J.CELL.2015.06.002 2015-06-03
6IBL ADRB1 β1 Adrenoceptors A (Rhodopsin) Common turkey N/A 6 3 0 0 6IBL 2.7 2019-01-09
5EE7 GLR glucagon Glucagon B1 (Secretin) Human in meso/LCP 11 3 0 2 5EE7 2.5 10.1038/NATURE17414 2016-04-20
2YDO AA2AR A2A Adenosine A (Rhodopsin) Human vapour diffusion 5 1 0 2 2YDO 3.0 10.1038/NATURE10136 2011-05-18
2HPY OPSD Rhodopsin Opsins A (Rhodopsin) Bovine vapour diffusion 0 0 0 0 2HPY 2.8 10.1073/PNAS.0601765103 2006-08-22
4RWA OPRD δ Opioid A (Rhodopsin) Human in meso/LCP 0 2 0 5 4RWA 3.3 10.1038/NSMB.2965 2015-01-14
5WQC OX2R OX2 Orexin A (Rhodopsin) Human in meso/LCP 1 3 0 4 5WQC 2.0 10.1016/J.STR.2017.11.005 2017-11-29
4PXZ P2Y12 P2Y12 P2Y A (Rhodopsin) Human in meso/LCP 1 1 0 5 4PXZ 2.5 10.1038/NATURE13288 2014-04-30
5K2C AA2AR A2A Adenosine A (Rhodopsin) Human in meso/LCP 0 3 0 4 5K2C 1.9 10.1126/SCIADV.1600292 2016-09-21
4BUO NTR1 NTS1 Neurotensin A (Rhodopsin) Rat vapour diffusion 11 3 0 8 4BUO 2.8 10.1073/PNAS.1317903111 2014-01-29
2Y01 ADRB1 β1 Adrenoceptors A (Rhodopsin) Common turkey vapour diffusion 8 3 0 1 2Y01 2.6 10.1038/NATURE09746 2011-03-30
5UIG AA2AR A2A Adenosine A (Rhodopsin) Human vapour diffusion 0 2 0 5 5UIG 3.5 10.1073/PNAS.1621423114 2017-02-08
4BV0 NTR1 NTS1 Neurotensin A (Rhodopsin) Rat vapour diffusion 29 3 0 8 4BV0 3.1 10.1073/PNAS.1317903111 2014-01-29
3AYM OPSD Rhodopsin Opsins A (Rhodopsin) Japanese flying squid vapour diffusion 0 0 0 0 3AYM 2.8 10.1016/J.JMB.2011.08.044 2011-08-17
4PXF OPSD Rhodopsin Opsins A (Rhodopsin) Bovine vapour diffusion 0 0 0 0 4PXF 2.8 10.1038/NCOMMS5801 2014-09-17
4LDL ADRB2 β2 Adrenoceptors A (Rhodopsin) Human in meso/LCP 4 3 0 3 4LDL 3.1 10.1038/NATURE12572 2013-09-25
2R4R ADRB2 β2 Adrenoceptors A (Rhodopsin) Human vapour diffusion 2 1 0 4 2R4R 3.4 10.1038/NATURE06325 2007-11-06
5VEX GLP1R GLP-1 Glucagon B1 (Secretin) Human in meso/LCP 10 4 0 5 5VEX 3.0 10.1038/NATURE22378 2017-05-17
4Z9G CRFR1 CRF1 Corticotropin-releasing factor B1 (Secretin) Human in meso/LCP 11 3 0 3 4Z9G 3.2 10.2174/1874467210666170110114727 2016-06-29
5OLG AA2AR A2A Adenosine A (Rhodopsin) Human in meso/LCP 9 3 0 4 5OLG 1.9 10.1038/S41598-017-18570-W 2018-01-17
5XR8 CNR1 CB1 Cannabinoid A (Rhodopsin) Human in meso/LCP 4 3 0 5 5XR8 3.0 10.1038/NATURE23272 2017-07-12
5XSZ Q08BG4 LPA6 Lysophospholipid (LPA) A (Rhodopsin) Zebrafish in meso/LCP 0 2 0 6 5XSZ 3.2 10.1038/NATURE23448 2017-08-16
3QAK AA2AR A2A Adenosine A (Rhodopsin) Human in meso/LCP 0 3 0 5 3QAK 2.7 10.1126/SCIENCE.1202793 2011-03-09
2YCY ADRB1 β1 Adrenoceptors A (Rhodopsin) Common turkey vapour diffusion 8 4 0 1 2YCY 3.2 10.1073/PNAS.1100185108 2011-06-08
5IUA AA2AR A2A Adenosine A (Rhodopsin) Human in meso/LCP 9 3 0 4 5IUA 2.2 10.1021/ACS.JMEDCHEM.6B00653 2016-06-29
4QKX ADRB2 β2 Adrenoceptors A (Rhodopsin) Human in meso/LCP 5 3 0 5 4QKX 3.3 10.1073/PNAS.1410415111 2014-07-23
5TE3 OPSD Rhodopsin Opsins A (Rhodopsin) Bovine vapour diffusion 0 0 0 0 5TE3 2.7 10.1073/PNAS.1617446114 2017-03-15
5VEW GLP1R GLP-1 Glucagon B1 (Secretin) Human in meso/LCP 10 4 0 5 5VEW 2.7 10.1038/NATURE22378 2017-05-24
2Y03 ADRB1 β1 Adrenoceptors A (Rhodopsin) Common turkey vapour diffusion 8 3 0 1 2Y03 2.9 10.1038/NATURE09746 2011-01-12
4S0V OX2R OX2 Orexin A (Rhodopsin) Human in meso/LCP 1 3 0 4 4S0V 2.5 10.1038/NATURE14035 2015-01-14
5K2D AA2AR A2A Adenosine A (Rhodopsin) Human in meso/LCP 0 3 0 4 5K2D 1.9 10.1126/SCIADV.1600292 2016-09-21
4XNW P2RY1 P2Y1 P2Y A (Rhodopsin) Human in meso/LCP 1 2 0 5 4XNW 2.7 10.1038/NATURE14287 2015-04-01
3DQB OPSD Rhodopsin Opsins A (Rhodopsin) Bovine vapour diffusion 0 0 0 0 3DQB 3.2 10.1038/NATURE07330 2008-09-23
2I37 OPSD Rhodopsin Opsins A (Rhodopsin) Bovine vapour diffusion 0 0 0 0 2I37 4.2 10.1073/PNAS.0608022103 2006-10-17
5D5A ADRB2 β2 Adrenoceptors A (Rhodopsin) Human in meso/LCP 3 2 0 2 5D5A 2.5 10.1107/S2059798315021683 2016-01-13
5NM4 AA2AR A2A Adenosine A (Rhodopsin) Human in meso/LCP 9 3 0 4 5NM4 1.7 10.1038/S41467-017-00630-4 2017-09-27
4NC3 5HT2B 5-HT2B 5-Hydroxytryptamine A (Rhodopsin) Human in meso/LCP 1 3 0 5 4NC3 2.8 10.1126/SCIENCE.1244142 2013-12-18
3OE6 CXCR4 CXCR4 Chemokine A (Rhodopsin) Human in meso/LCP 1 2 0 7 3OE6 3.2 10.1126/SCIENCE.1194396 2010-10-27
6FK9 OPSD Rhodopsin Opsins A (Rhodopsin) Bovine vapour diffusion 2 0 0 0 6FK9 2.6 10.1073/PNAS.1718084115 2018-04-04
5UNG AGTR2 AT2 Angiotensin A (Rhodopsin) Human in meso/LCP 0 2 0 6 5UNG 2.8 10.1038/NATURE22035 2017-04-05
5T1A CCR2 CCR2 Chemokine A (Rhodopsin) Human in meso/LCP 0 3 0 6 5T1A 2.8 10.1038/NATURE20605 2016-12-14
4U14 ACM3 M3 Acetylcholine (muscarinic) A (Rhodopsin) Rat sponge mesophase 0 3 0 4 4U14 3.6 10.1016/J.STR.2014.08.022 2014-11-26
6FKD OPSD Rhodopsin Opsins A (Rhodopsin) Bovine vapour diffusion 2 0 0 0 6FKD 2.5 10.1073/PNAS.1718084115 2018-04-04
5NX2 GLP1R GLP-1 Glucagon B1 (Secretin) Human vapour diffusion 12 2 0 5 5NX2 3.7 10.1038/NATURE22800 2017-06-14
5EN0 OPSD Rhodopsin Opsins A (Rhodopsin) Bovine vapour diffusion 3 0 0 0 5EN0 2.8 10.15252/EMBR.201642671 2016-08-10
3ZEV NTR1 NTS1 Neurotensin A (Rhodopsin) Rat vapour diffusion 11 3 0 8 3ZEV 3.0 10.1073/PNAS.1317903111 2014-01-29
3V2W S1PR1 S1P1 Lysophospholipid (S1P) A (Rhodopsin) Human in meso/LCP 2 4 0 5 3V2W 3.4 10.1126/SCIENCE.1215904 2012-02-15
4DJH OPRK κ Opioid A (Rhodopsin) Human in meso/LCP 1 3 0 5 4DJH 2.9 10.1038/NATURE10939 2012-03-21
4N4W SMO SMO Frizzled F (Frizzled) Human in meso/LCP 0 2 0 5 4N4W 2.8 10.1038/NCOMMS5355 2014-01-22
PDB UniProt Receptor
3VW7 PAR1 PAR1
4ZJC OX1R OX1
2J4Y OPSD Rhodopsin
2Y02 ADRB1 β1
3OE8 CXCR4 CXCR4
3SN6 ADRB2 β2
4JKV SMO SMO
4PHU FFAR1 FFA1
4U15 ACM3 M3
4Z35 LPAR1 LPA1
5L7I SMO SMO
5NM2 AA2AR A2A
5UIW CCR5 CCR5
5XF1 GLR glucagon
6D35 Q98SW5 SMO
5TGZ CNR1 CB1
3NY9 ADRB2 β2
5YQZ GLR glucagon
5WF6 AA2AR A2A
1GZM OPSD Rhodopsin
6D32 Q98SW5 SMO
6D9H AA1R A1
5LWE CCR9 CCR9
6E3Y CALRL calcitonin-like
5UVI AA2AR A2A
4MQT ACM2 M2
4ZWJ OPSD Rhodopsin
5UZ7 CALCR CT
5TZR FFAR1 FFA1
4BEY OPSD Rhodopsin
4X1H OPSD Rhodopsin
5L7D SMO SMO
3UZA AA2AR A2A
4GRV NTR1 NTS1
4UHR AA2AR A2A
4IAQ 5HT1B 5-HT1B
5OM1 AA2AR A2A
2Z73 OPSD Rhodopsin
5DYS OPSD Rhodopsin
4NTJ P2Y12 P2Y12
6FFH GRM5 mGlu5
3OE0 CXCR4 CXCR4
4MBS CCR5 CCR5
4DKL OPRM μ
5VAI G1SGD4 GLP-1
5XRA CNR1 CB1
5IUB AA2AR A2A
4BWB NTR1 NTS1
6C1R C5AR1 C5a1
5VRA AA2AR A2A
5WB1 Q80KM9 US28
5D5B ADRB2 β2
5X93 EDNRB ETB
4OO9 GRM5 mGlu5
4EJ4 OPRD δ
5WS3 OX2R OX2
6CMO OPSD Rhodopsin
2RH1 ADRB2 β2
5UEN AA1R A1
3KJ6 ADRB2 β2
6M9T PE2R3 EP3
5DSG ACM4 M4
4AMJ ADRB1 β1
4OR2 GRM1 mGlu1
5V57 SMO SMO
5TE5 OPSD Rhodopsin
5OLZ AA2AR A2A
4BVN ADRB1 β1
5JQH ADRB2 β2
5VBL APJ apelin
3RZE HRH1 H1
2R4S ADRB2 β2
5OLO AA2AR A2A
5IU8 AA2AR A2A
6C1Q C5AR1 C5a1
5N2S AA1R A1
5WF5 AA2AR A2A
3OE9 CXCR4 CXCR4
3P0G ADRB2 β2
3PBL DRD3 D3
3V2Y S1PR1 S1P1
5DHG OPRX NOP
5MZP AA2AR A2A
5OLH AA2AR A2A
5T04 NTR1 NTS1
5ZKC ACM2 M2
6B3J GLP1R GLP-1
6CM4 DRD2 D2
6DRX 5HT2B 5-HT2B
4BEZ OPSD Rhodopsin
3NY8 ADRB2 β2
5YWY PE2R4 EP4
6FK6 OPSD Rhodopsin
4LDE ADRB2 β2
5WB2 Q80KM9 US28
5XEZ GLR glucagon
6H7J ADRB1 β1
5YC8 ACM2 M2
5ZKP PTAFR PAF
4ZJ8 OX1R OX1
4MQS ACM2 M2
4RWD OPRD δ
4K5Y CRFR1 CRF1
2Y04 ADRB1 β1
3VGA AA2AR A2A
1L9H OPSD Rhodopsin
5IU4 AA2AR A2A
6HLO NK1R NK1
6D26 PD2R2 DP2
1HZX OPSD Rhodopsin
6GPX CCR2 CCR2
5N2R AA2AR A2A
6IGL EDNRB ETB
5ZKQ PTAFR PAF
6H7N ADRB1 β1
5WIU DRD4 D4
3EML AA2AR A2A
2G87 OPSD Rhodopsin
3REY AA2AR A2A
6IIV TA2R TP
5CGD GRM5 mGlu5
6MXT ADRB2 β2
3UON ACM2 M2
4WW3 OPSD Rhodopsin
5MZJ AA2AR A2A
4J4Q OPSD Rhodopsin
4ZUD AGTR1 AT1
5TZY FFAR1 FFA1
4EIY AA2AR A2A
6FK7 OPSD Rhodopsin
4XES NTR1 NTS1
3UZC AA2AR A2A
6DDF OPRM μ
5V56 SMO SMO
5CXV ACM1 M1
4AMI ADRB1 β1
4N6H OPRD δ
5F8U ADRB1 β1
4PY0 P2Y12 P2Y12
5O9H C5AR1 C5a1
3PQR OPSD Rhodopsin
5ZBH NPY1R Y1
5C1M OPRM μ
3OAX OPSD Rhodopsin
6AKX CCR5 CCR5
2VT4 ADRB1 β1
5X33 Q9WTK1 BLT1
6FJ3 PTH1R PTH1
6B73 OPRK κ
5G53 AA2AR A2A
6HLP NK1R NK1
2YCX ADRB1 β1
3PDS ADRB2 β2
6HLL NK1R NK1
2PED OPSD Rhodopsin
5JTB AA2AR A2A
6AK3 PE2R3 EP3
5NJ6 PAR2 PAR2
3C9M OPSD Rhodopsin
3PWH AA2AR A2A
4LDO ADRB2 β2
4QIN SMO SMO
4U16 ACM3 M3
4XNV P2RY1 P2Y1
4XT1 US28 US28
5IU7 AA2AR A2A
5OM4 AA2AR A2A
5UNH AGTR2 AT2
5WIV DRD4 D4
5WKT OPSD Rhodopsin
6H7L ADRB1 β1
6H7M ADRB1 β1
6MET CCR5 CCR5
4IAR 5HT1B 5-HT1B
6FKA OPSD Rhodopsin
6MEO CCR5 CCR5
6FK8 OPSD Rhodopsin
3ZPR ADRB1 β1
6FUF OPSD Rhodopsin
5XPR EDNRB ETB
6BQG 5HT2C 5-HT2C
2YDV AA2AR A2A
5ZK8 ACM2 M2
5A8E ADRB1 β1
6FFI GRM5 mGlu5
6IGK EDNRB ETB
5DGY OPSD Rhodopsin
5DHH OPRX NOP
2YCW ADRB1 β1
2YCZ ADRB1 β1
4QIM SMO SMO
6GPS CCR2 CCR2
4EA3 OPRX NOP
5CGC GRM5 mGlu5
6DRY 5HT2B 5-HT2B
1F88 OPSD Rhodopsin
6D27 PD2R2 DP2
5ZKB ACM2 M2
5X7D ADRB2 β2
5W0P OPSD Rhodopsin
4DAJ ACM3 M3
5TVN 5HT2B 5-HT2B
4A4M OPSD Rhodopsin
6FKB OPSD Rhodopsin
3D4S ADRB2 β2
4XEE NTR1 NTS1
5UNF AGTR2 AT2
3CAP OPSD Rhodopsin
4O9R SMO SMO
4UG2 AA2AR A2A
6IIU TA2R TP
5ZBQ NPY1R Y1
6DRZ 5HT2B 5-HT2B
5K2B AA2AR A2A
5NLX AA2AR A2A
2ZIY OPSD Rhodopsin
4YAY AGTR1 AT1
5KW2 FFAR1 FFA1
5GLI EDNRB ETB
4GPO ADRB1 β1
6AKY CCR5 CCR5
4XT3 US28 US28
6E59 NK1R NK1
4GBR ADRB2 β2
6H7O ADRB1 β1
2X72 OPSD Rhodopsin
5XJM AGTR2 AT2
6GDG AA2AR A2A
6DS0 5HT2B 5-HT2B
3RFM AA2AR A2A
5ZK3 ACM2 M2
6DDE OPRM μ
5OLV AA2AR A2A
5V54 5HT1B 5-HT1B
5GLH EDNRB ETB
5D6L ADRB2 β2
2I35 OPSD Rhodopsin
5NDD PAR2 PAR2
5NDZ PAR2 PAR2
4IB4 5HT2B 5-HT2B
1U19 OPSD Rhodopsin
2Y00 ADRB1 β1
3C9L OPSD Rhodopsin
3PXO OPSD Rhodopsin
3VG9 AA2AR A2A
4L6R GLR glucagon
4RWS CXCR4 CXCR4
4Z36 LPAR1 LPA1
5K2A AA2AR A2A
5TUD 5HT2B 5-HT2B
6AQF AA2AR A2A
6FKC OPSD Rhodopsin
6G79 5HT1B 5-HT1B
3ZPQ ADRB1 β1
3AYN OPSD Rhodopsin
3ODU CXCR4 CXCR4
5U09 CNR1 CB1
6BQH 5HT2C 5-HT2C
5YHL PE2R4 EP4
3NYA ADRB2 β2
2I36 OPSD Rhodopsin
4Z34 LPAR1 LPA1
6IBL ADRB1 β1
5EE7 GLR glucagon
2YDO AA2AR A2A
2HPY OPSD Rhodopsin
4RWA OPRD δ
5WQC OX2R OX2
4PXZ P2Y12 P2Y12
5K2C AA2AR A2A
4BUO NTR1 NTS1
2Y01 ADRB1 β1
5UIG AA2AR A2A
4BV0 NTR1 NTS1
3AYM OPSD Rhodopsin
4PXF OPSD Rhodopsin
4LDL ADRB2 β2
2R4R ADRB2 β2
5VEX GLP1R GLP-1
4Z9G CRFR1 CRF1
5OLG AA2AR A2A
5XR8 CNR1 CB1
5XSZ Q08BG4 LPA6
3QAK AA2AR A2A
2YCY ADRB1 β1
5IUA AA2AR A2A
4QKX ADRB2 β2
5TE3 OPSD Rhodopsin
5VEW GLP1R GLP-1
2Y03 ADRB1 β1
4S0V OX2R OX2
5K2D AA2AR A2A
4XNW P2RY1 P2Y1
3DQB OPSD Rhodopsin
2I37 OPSD Rhodopsin
5D5A ADRB2 β2
5NM4 AA2AR A2A
4NC3 5HT2B 5-HT2B
3OE6 CXCR4 CXCR4
6FK9 OPSD Rhodopsin
5UNG AGTR2 AT2
5T1A CCR2 CCR2
4U14 ACM3 M3
6FKD OPSD Rhodopsin
5NX2 GLP1R GLP-1
5EN0 OPSD Rhodopsin
3ZEV NTR1 NTS1
3V2W S1PR1 S1P1
4DJH OPRK κ
4N4W SMO SMO
 
N-term
TM1
ICL1
TM2
ECL1
TM3
ICL2
TM4
ECL2
TM5
ICL3
TM6
ECL3
TM7
H8
C-term
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
 
 
 
 
ECL2
 
TM5
 
 
 
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
 
TM5
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
ICL3
 
 
 
 
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
 
 
ECL3
 
TM7
 
H8
 
C-term
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
N-term
 
 
 
TM1
 
ICL1
 
 
 
TM2
 
ECL1
 
 
 
TM3
 
ICL2
 
TM4
 
ECL2
 
 
 
 
TM5
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
ICL3
 
 
 
TM6
 
ECL3
 
 
 
 
 
TM7
 
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
 
 
TM3
 
ICL2
 
TM4
 
ECL2
 
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
N-term
 
 
 
TM1
 
ICL1
 
 
TM2
 
 
 
ECL1
 
TM3
 
ICL2
 
TM4
 
 
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
N-term
 
TM1
 
ICL1
 
 
 
TM2
 
ECL1
 
 
 
 
 
TM3
 
ICL2
 
TM4
 
ECL2
 
 
 
TM5
 
 
 
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
 
 
 
 
TM5
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
ICL3
 
 
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
 
 
 
 
 
TM5
 
 
 
 
ICL3
 
 
 
TM6
 
ECL3
 
TM7
 
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
 
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
 
 
TM3
 
ICL2
 
TM4
 
ECL2
 
 
 
 
TM5
 
 
 
 
 
 
 
 
ICL3
 
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
 
TM1
 
ICL1
 
 
 
TM2
 
ECL1
 
 
 
 
 
TM3
 
ICL2
 
 
 
TM4
 
 
 
ECL2
 
 
 
 
 
 
TM5
 
 
 
 
 
ICL3
 
 
 
 
 
TM6
 
ECL3
 
 
 
TM7
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
 
N-term
 
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
 
 
TM4
 
ECL2
 
 
TM5
 
 
 
ICL3
 
 
 
TM6
 
ECL3
 
TM7
 
 
 
H8
 
 
 
 
C-term
 
 
 
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
 
 
 
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
 
 
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
 
 
 
TM5
 
 
 
 
 
 
 
 
ICL3
 
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
 
 
TM3
 
ICL2
 
TM4
 
ECL2
 
 
 
 
 
 
 
TM5
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
ICL3
 
 
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
 
 
N-term
 
 
TM1
 
ICL1
 
TM2
 
ECL1
 
 
 
TM3
 
ICL2
 
TM4
 
 
 
ECL2
 
 
 
 
 
TM5
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
ICL3
 
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
 
 
 
 
N-term
 
TM1
 
ICL1
 
 
 
TM2
 
ECL1
 
TM3
 
 
 
 
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
 
TM1
 
ICL1
 
TM2
 
ECL1
 
 
 
TM3
 
ICL2
 
TM4
 
ECL2
 
 
 
 
TM5
 
 
 
 
 
ICL3
 
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
 
 
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
 
 
 
TM5
 
 
 
 
 
 
 
 
ICL3
 
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
 
 
 
 
 
 
 
 
 
 
 
 
 
N-term
 
TM1
 
 
 
 
ICL1
 
 
TM2
 
ECL1
 
 
 
TM3
 
ICL2
 
TM4
 
ECL2
 
 
 
TM5
 
ICL3
 
 
 
TM6
 
ECL3
 
 
 
 
 
TM7
 
 
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
 
 
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
 
 
 
TM5
 
 
 
 
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
 
 
 
 
 
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
 
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
 
 
TM6
 
 
 
ECL3
 
TM7
 
H8
 
C-term
 
 
 
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
N-term
 
TM1
 
ICL1
 
 
 
TM2
 
ECL1
 
 
 
 
 
TM3
 
ICL2
 
TM4
 
ECL2
 
 
 
TM5
 
 
 
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
 
N-term
 
TM1
 
ICL1
 
 
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
 
 
ECL3
 
TM7
 
H8
 
C-term
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
 
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
 
 
TM3
 
ICL2
 
TM4
 
ECL2
 
 
 
 
TM5
 
 
 
 
 
 
 
 
ICL3
 
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
TM1
 
ICL1
 
 
 
TM2
 
ECL1
 
 
 
 
 
TM3
 
ICL2
 
 
 
TM4
 
ECL2
 
 
 
TM5
 
ICL3
 
 
 
 
 
TM6
 
ECL3
 
 
 
TM7
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
N-term
 
 
 
TM1
 
ICL1
 
TM2
 
ECL1
 
 
 
TM3
 
ICL2
 
TM4
 
 
 
ECL2
 
 
 
 
 
TM5
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
ICL3
 
 
 
 
 
TM6
 
ECL3
 
 
 
 
 
TM7
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
TM1
 
ICL1
 
 
 
 
 
 
 
TM2
 
ECL1
 
 
 
TM3
 
ICL2
 
TM4
 
 
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
 
 
TM3
 
ICL2
 
TM4
 
ECL2
 
 
 
 
TM5
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
ICL3
 
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
 
TM1
 
ICL1
 
 
 
TM2
 
ECL1
 
 
 
 
 
TM3
 
ICL2
 
 
 
TM4
 
 
 
ECL2
 
 
 
 
 
 
TM5