G Protein Couplings
| Source | Receptor | Ligand | Guide to Pharmacology | Log(Emax/EC50) | pEC50 | Emax | Standard Deviation | ||||||||||||||||||||||
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| Group | Biosensor | Cl | Receptor fam. |
Uniprot
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| GPCRdb | Mean | A | 5-Hydroxytryptamine | 5HT1A | 5-HT1A | - | - | 1' | - | - | 5.2 | 7.0 | 6.0 | 5.2 | 5.9 | 7.3 | 6.4 | 5.8 | 22 | 54 | 43 | 26 | 2.1 | 16.0 | 15.8 | 3.8 | 1 | ||
| Bouvier | GEMTA | A | 5-Hydroxytryptamine | 5HT1A | 5-HT1A | 5-hydroxytryptamine | Physiological | - | 1' | - | - | - | 8.0 | 6.1 | - | - | 8.2 | 6.5 | - | - | 61 | 46 | - | - | 26.8 | 26.8 | - | Bouvier | |
| Inoue | TGF | A | 5-Hydroxytryptamine | 5HT1A | 5-HT1A | 5-hydroxytryptamine | Physiological | - | 1' | - | - | 5.2 | 6.1 | 5.9 | 5.2 | 5.9 | 6.5 | 6.3 | 5.8 | 22 | 46 | 40 | 26 | 2.1 | 5.2 | 4.8 | 3.8 | Inoue | |
| GPCRdb | Mean | A | 5-Hydroxytryptamine | 5HT1A | 5-HT1A | - | - | 1' | - | - | - | 7.0 | 6.0 | - | - | 7.3 | 6.4 | - | - | 54 | 43 | - | - | 16.0 | 15.8 | - | 2 | ||
| GPCRdb | Mean | A | 5-Hydroxytryptamine | 5HT1A | 5-HT1A | - | - | 1' | - | - | - | 7.0 | - | - | - | 7.3 | - | - | - | 54 | - | - | - | 16.0 | - | - | 3 | ||
| GPCRdb | Mean | A | 5-Hydroxytryptamine | 5HT1A | 5-HT1A | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | 4 | ||
| GPCRdb | Mean | A | 5-Hydroxytryptamine | 5HT1B | 5-HT1B | - | - | 1' | - | - | - | 7.8 | 6.3 | 6.1 | - | 8.4 | 7.2 | 7.1 | - | 26 | 15 | 11 | - | 7.3 | 6.4 | 19.3 | 1 | ||
| Bouvier | GEMTA | A | 5-Hydroxytryptamine | 5HT1B | 5-HT1B | 5-hydroxytryptamine | Physiological | - | 1' | - | - | - | 8.7 | 6.2 | - | - | 9.4 | 7.2 | - | - | 26 | 12 | - | - | 8.2 | 9.1 | - | Bouvier | |
| Inoue | TGF | A | 5-Hydroxytryptamine | 5HT1B | 5-HT1B | 5-hydroxytryptamine | Physiological | - | 1' | - | - | - | 6.9 | 6.4 | 6.1 | - | 7.5 | 7.2 | 7.1 | - | 27 | 18 | 11 | - | 6.5 | 3.7 | 19.3 | Inoue | |
| GPCRdb | Mean | A | 5-Hydroxytryptamine | 5HT1B | 5-HT1B | - | - | 1' | - | - | - | 7.8 | 6.3 | - | - | 8.4 | 7.2 | - | - | 26 | 15 | - | - | 7.3 | 6.4 | - | 2 | ||
| GPCRdb | Mean | A | 5-Hydroxytryptamine | 5HT1B | 5-HT1B | - | - | 1' | - | - | - | 7.8 | - | - | - | 8.4 | - | - | - | 26 | - | - | - | 7.3 | - | - | 3 | ||
| GPCRdb | Mean | A | 5-Hydroxytryptamine | 5HT1B | 5-HT1B | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | 4 | ||
| GPCRdb | Mean | A | 5-Hydroxytryptamine | 5HT1D | 5-HT1D | - | - | 1' | - | - | - | 7.9 | 7.1 | 6.8 | - | 8.6 | 8.0 | 7.8 | - | 26 | 20 | 10 | - | 4.2 | 1.5 | 1.0 | 1 | ||
| Bouvier | GEMTA | A | 5-Hydroxytryptamine | 5HT1D | 5-HT1D | 5-hydroxytryptamine | Physiological | - | 1' | - | - | - | 7.7 | - | - | - | 8.4 | - | - | - | 21 | - | - | - | 5.4 | - | - | Bouvier | |
| Inoue | TGF | A | 5-Hydroxytryptamine | 5HT1D | 5-HT1D | 5-hydroxytryptamine | Physiological | - | 1' | - | - | - | 8.2 | 7.1 | 6.8 | - | 8.8 | 8.0 | 7.8 | - | 31 | 20 | 10 | - | 2.9 | 1.5 | 1.0 | Inoue | |
| GPCRdb | Mean | A | 5-Hydroxytryptamine | 5HT1D | 5-HT1D | - | - | 1' | - | - | - | 7.9 | - | - | - | 8.6 | - | - | - | 26 | - | - | - | 4.2 | - | - | 2 | ||
| GPCRdb | Mean | A | 5-Hydroxytryptamine | 5HT1D | 5-HT1D | - | - | 1' | - | - | - | 7.9 | - | - | - | 8.6 | - | - | - | 26 | - | - | - | 4.2 | - | - | 3 | ||
| GPCRdb | Mean | A | 5-Hydroxytryptamine | 5HT1D | 5-HT1D | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | 4 | ||
| GPCRdb | Mean | A | 5-Hydroxytryptamine | 5HT1E | 5-HT1E | - | - | 1' | - | - | - | 6.7 | - | - | - | 7.5 | - | - | - | 20 | - | - | - | 8.0 | - | - | 1 | ||
| Inoue | TGF | A | 5-Hydroxytryptamine | 5HT1E | 5-HT1E | 5-hydroxytryptamine | Physiological | - | 1' | - | - | - | 6.7 | - | - | - | 7.5 | - | - | - | 20 | - | - | - | 8.0 | - | - | Inoue | |
| GPCRdb | Mean | A | 5-Hydroxytryptamine | 5HT1E | 5-HT1E | - | - | 1' | - | - | - | 6.7 | - | - | - | 7.5 | - | - | - | 20 | - | - | - | 8.0 | - | - | 2 | ||
| GPCRdb | Mean | A | 5-Hydroxytryptamine | 5HT1E | 5-HT1E | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | 3 | ||
| GPCRdb | Mean | A | 5-Hydroxytryptamine | 5HT1E | 5-HT1E | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | 4 | ||
| GPCRdb | Mean | A | 5-Hydroxytryptamine | 5HT1F | 5-HT1F | - | - | 1' | - | - | - | 6.5 | - | - | - | 7.3 | - | - | - | 16 | - | - | - | 1.7 | - | - | 1 | ||
| Inoue | TGF | A | 5-Hydroxytryptamine | 5HT1F | 5-HT1F | 5-hydroxytryptamine | Physiological | - | 1' | - | - | - | 6.5 | - | - | - | 7.3 | - | - | - | 16 | - | - | - | 1.7 | - | - | Inoue | |
| GPCRdb | Mean | A | 5-Hydroxytryptamine | 5HT1F | 5-HT1F | - | - | 1' | - | - | - | 6.5 | - | - | - | 7.3 | - | - | - | 16 | - | - | - | 1.7 | - | - | 2 | ||
| GPCRdb | Mean | A | 5-Hydroxytryptamine | 5HT1F | 5-HT1F | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | 3 | ||
| GPCRdb | Mean | A | 5-Hydroxytryptamine | 5HT1F | 5-HT1F | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | 4 | ||
| GPCRdb | Mean | A | 5-Hydroxytryptamine | 5HT2A | 5-HT2A | - | - | 2' | 1' | - | 5.5 | 6.5 | 8.0 | 6.0 | 6.2 | 7.2 | 8.5 | 6.3 | 24 | 26 | 30 | 38 | 13.9 | 4.2 | 19.9 | 8.3 | 1 | ||
| Bouvier | GEMTA | A | 5-Hydroxytryptamine | 5HT2A | 5-HT2A | 5-hydroxytryptamine | Physiological | - | 2' | 1' | - | - | 6.1 | 8.5 | - | - | 7.0 | 9.0 | - | - | 16 | 34 | - | - | 2.5 | 32.6 | - | Bouvier | |
| Inoue | TGF | A | 5-Hydroxytryptamine | 5HT2A | 5-HT2A | 5-hydroxytryptamine | Physiological | - | 2' | 1' | - | 5.5 | 7.0 | 7.4 | 6.0 | 6.2 | 7.5 | 8.0 | 6.3 | 24 | 37 | 27 | 38 | 13.9 | 5.9 | 7.2 | 8.3 | Inoue | |
| GPCRdb | Mean | A | 5-Hydroxytryptamine | 5HT2A | 5-HT2A | - | - | 2' | 1' | - | - | 6.5 | 8.0 | - | - | 7.2 | 8.5 | - | - | 26 | 30 | - | - | 4.2 | 19.9 | - | 2 | ||
| GPCRdb | Mean | A | 5-Hydroxytryptamine | 5HT2A | 5-HT2A | - | - | 2' | 1' | - | - | 6.5 | 8.0 | - | - | 7.2 | 8.5 | - | - | 26 | 30 | - | - | 4.2 | 19.9 | - | 3 | ||
| GPCRdb | Mean | A | 5-Hydroxytryptamine | 5HT2A | 5-HT2A | - | - | 2' | 1' | - | - | 2' | 1' | - | - | 2' | 1' | - | - | 2' | 1' | - | - | 2' | 1' | - | 4 | ||
| GPCRdb | Mean | A | 5-Hydroxytryptamine | 5HT2B | 5-HT2B | - | - | - | 1' | - | 6.2 | 7.3 | 7.5 | 6.2 | 7.3 | 8.1 | 8.3 | 7.4 | 8 | 22 | 21 | 6 | 5.3 | 10.0 | 9.8 | 2.3 | 1 | ||
| Bouvier | GEMTA | A | 5-Hydroxytryptamine | 5HT2B | 5-HT2B | 5-hydroxytryptamine | Physiological | - | - | 1' | - | - | 7.5 | 7.6 | - | - | 8.3 | 8.3 | - | - | 18 | 22 | - | - | 6.7 | 9.3 | - | Bouvier | |
| Inoue | TGF | A | 5-Hydroxytryptamine | 5HT2B | 5-HT2B | 5-hydroxytryptamine | Physiological | - | - | 1' | - | 6.2 | 7.2 | 7.5 | 6.2 | 7.3 | 7.8 | 8.3 | 7.4 | 8 | 27 | 20 | 6 | 5.3 | 13.3 | 10.2 | 2.3 | Inoue | |
| GPCRdb | Mean | A | 5-Hydroxytryptamine | 5HT2B | 5-HT2B | - | - | - | 1' | - | - | 7.3 | 7.5 | - | - | 8.1 | 8.3 | - | - | 22 | 21 | - | - | 10.0 | 9.8 | - | 2 | ||
| GPCRdb | Mean | A | 5-Hydroxytryptamine | 5HT2B | 5-HT2B | - | - | - | 1' | - | - | - | 7.5 | - | - | - | 8.3 | - | - | - | 21 | - | - | - | 9.8 | - | 3 | ||
| GPCRdb | Mean | A | 5-Hydroxytryptamine | 5HT2B | 5-HT2B | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | 4 | ||
| GPCRdb | Mean | A | 5-Hydroxytryptamine | 5HT2C | 5-HT2C | - | - | 2' | 1' | - | 6.3 | 7.7 | 8.1 | 7.6 | 6.8 | 8.2 | 8.6 | 7.8 | 31 | 40 | 40 | 50 | 14.2 | 20.4 | 27.2 | 17.5 | 1 | ||
| Bouvier | GEMTA | A | 5-Hydroxytryptamine | 5HT2C | 5-HT2C | 5-hydroxytryptamine | Physiological | - | 2' | 1' | - | - | 7.5 | 8.4 | 7.7 | - | 7.7 | 8.6 | 7.8 | - | 62 | 62 | 64 | - | 36.4 | 50.0 | 21.4 | Bouvier | |
| Inoue | TGF | A | 5-Hydroxytryptamine | 5HT2C | 5-HT2C | 5-hydroxytryptamine | Physiological | - | 2' | 1' | - | 6.3 | 7.9 | 7.8 | 7.4 | 6.8 | 8.7 | 8.6 | 7.8 | 31 | 17 | 17 | 36 | 14.2 | 4.5 | 4.4 | 13.6 | Inoue | |
| GPCRdb | Mean | A | 5-Hydroxytryptamine | 5HT2C | 5-HT2C | - | - | 2' | 1' | - | - | 7.7 | 8.1 | 7.6 | - | 8.2 | 8.6 | 7.8 | - | 40 | 40 | 50 | - | 20.4 | 27.2 | 17.5 | 2 | ||
| GPCRdb | Mean | A | 5-Hydroxytryptamine | 5HT2C | 5-HT2C | - | - | 2' | 1' | - | - | 7.7 | 8.1 | - | - | 8.2 | 8.6 | - | - | 40 | 40 | - | - | 20.4 | 27.2 | - | 3 | ||
| GPCRdb | Mean | A | 5-Hydroxytryptamine | 5HT2C | 5-HT2C | - | - | 2' | 1' | - | - | 2' | 1' | - | - | 2' | 1' | - | - | 2' | 1' | - | - | 2' | 1' | - | 4 | ||
| GPCRdb | Mean | A | 5-Hydroxytryptamine | 5HT4R | 5-HT4 | - | 1' | - | - | 2' | 6.5 | 7.2 | 6.7 | 6.2 | 7.0 | 7.5 | 7.1 | 6.7 | 44 | 41 | 38 | 35 | 10.7 | 10.3 | 11.6 | 13.9 | 1 | ||
| Inoue | TGF | A | 5-Hydroxytryptamine | 5HT4R | 5-HT4 | 5-hydroxytryptamine | Physiological | 1' | - | - | 2' | 6.5 | 7.2 | 6.7 | 6.2 | 7.0 | 7.5 | 7.1 | 6.7 | 44 | 41 | 38 | 35 | 10.7 | 10.3 | 11.6 | 13.9 | Inoue | |
| GPCRdb | Mean | A | 5-Hydroxytryptamine | 5HT4R | 5-HT4 | - | 1' | - | - | 2' | 6.5 | - | - | 6.2 | 7.0 | - | - | 6.7 | 44 | - | - | 35 | 10.7 | - | - | 13.9 | 2 | ||
| GPCRdb | Mean | A | 5-Hydroxytryptamine | 5HT4R | 5-HT4 | - | 1' | - | - | 2' | 1' | - | - | 2' | 1' | - | - | 2' | 1' | - | - | 2' | 1' | - | - | 2' | 3 | ||
| GPCRdb | Mean | A | 5-Hydroxytryptamine | 5HT4R | 5-HT4 | - | 1' | - | - | 2' | 1' | - | - | 2' | 1' | - | - | 2' | 1' | - | - | 2' | 1' | - | - | 2' | 4 | ||
| GPCRdb | Mean | A | 5-Hydroxytryptamine | 5HT5A | 5-HT5A | - | - | 1' | 2' | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 1 | ||
| GPCRdb | Mean | A | 5-Hydroxytryptamine | 5HT5A | 5-HT5A | - | - | 1' | 2' | - | - | 1' | 2' | - | - | 1' | 2' | - | - | 1' | 2' | - | - | 1' | 2' | - | 2 | ||
| GPCRdb | Mean | A | 5-Hydroxytryptamine | 5HT5A | 5-HT5A | - | - | 1' | 2' | - | - | 1' | 2' | - | - | 1' | 2' | - | - | 1' | 2' | - | - | 1' | 2' | - | 3 | ||
| GPCRdb | Mean | A | 5-Hydroxytryptamine | 5HT5A | 5-HT5A | - | - | 1' | 2' | - | - | 1' | 2' | - | - | 1' | 2' | - | - | 1' | 2' | - | - | 1' | 2' | - | 4 | ||
| GPCRdb | Mean | A | 5-Hydroxytryptamine | 5HT6R | 5-HT6 | - | 1' | - | 2' | - | 6.4 | 6.2 | 5.8 | 5.5 | 6.8 | 6.6 | 6.7 | 6.2 | 43 | 40 | 17 | 23 | 7.9 | 4.3 | 1.0 | 2.5 | 1 | ||
| Inoue | TGF | A | 5-Hydroxytryptamine | 5HT6R | 5-HT6 | 5-hydroxytryptamine | Physiological | 1' | - | 2' | - | 6.4 | 6.2 | 5.8 | 5.5 | 6.8 | 6.6 | 6.7 | 6.2 | 43 | 40 | 17 | 23 | 7.9 | 4.3 | 1.0 | 2.5 | Inoue | |
| GPCRdb | Mean | A | 5-Hydroxytryptamine | 5HT6R | 5-HT6 | - | 1' | - | 2' | - | 6.4 | - | 5.8 | - | 6.8 | - | 6.7 | - | 43 | - | 17 | - | 7.9 | - | 1.0 | - | 2 | ||
| GPCRdb | Mean | A | 5-Hydroxytryptamine | 5HT6R | 5-HT6 | - | 1' | - | 2' | - | 1' | - | 2' | - | 1' | - | 2' | - | 1' | - | 2' | - | 1' | - | 2' | - | 3 | ||
| GPCRdb | Mean | A | 5-Hydroxytryptamine | 5HT6R | 5-HT6 | - | 1' | - | 2' | - | 1' | - | 2' | - | 1' | - | 2' | - | 1' | - | 2' | - | 1' | - | 2' | - | 4 | ||
| GPCRdb | Mean | A | 5-Hydroxytryptamine | 5HT7R | 5-HT7 | - | 1' | - | - | - | 8.1 | 8.2 | 8.2 | 8.2 | 8.5 | 8.9 | 8.8 | 8.9 | 40 | 18 | 24 | 18 | 9.2 | 4.4 | 3.9 | 4.3 | 1 | ||
| Inoue | TGF | A | 5-Hydroxytryptamine | 5HT7R | 5-HT7 | 5-hydroxytryptamine | Physiological | 1' | - | - | - | 8.3 | 8.2 | 8.2 | 8.2 | 8.8 | 8.9 | 8.8 | 8.9 | 34 | 18 | 24 | 18 | 9.2 | 4.4 | 3.9 | 4.3 | Inoue | |
| Roth | TGF | A | 5-Hydroxytryptamine | 5HT7R | 5-HT7 | 5-hydroxytryptamine | Physiological | 1' | - | - | - | 7.8 | - | - | - | 8.2 | - | - | - | 47 | - | - | - | - | - | - | - | Roth | |
| GPCRdb | Mean | A | 5-Hydroxytryptamine | 5HT7R | 5-HT7 | - | 1' | - | - | - | 8.1 | - | - | - | 8.5 | - | - | - | 40 | - | - | - | 9.2 | - | - | - | 2 | ||
| GPCRdb | Mean | A | 5-Hydroxytryptamine | 5HT7R | 5-HT7 | - | 1' | - | - | - | 8.1 | - | - | - | 8.5 | - | - | - | 40 | - | - | - | 1' | - | - | - | 3 | ||
| GPCRdb | Mean | A | 5-Hydroxytryptamine | 5HT7R | 5-HT7 | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 4 | ||
| GPCRdb | Mean | A | Acetylcholine (muscarinic) | ACM1 | M1 | - | - | - | 1' | - | 6.2 | 6.0 | 7.6 | 5.5 | 6.3 | 6.3 | 7.7 | 5.7 | 73 | 63 | 80 | 76 | 5.9 | 7.9 | 38.8 | 4.3 | 1 | ||
| Bouvier | GEMTA | A | Acetylcholine (muscarinic) | ACM1 | M1 | acetylcholine | Physiological | - | - | 1' | - | 5.8 | 5.0 | 7.7 | - | 6.1 | 5.5 | 7.8 | - | 52 | 38 | 78 | - | 5.1 | 11.1 | 73.5 | - | Bouvier | |
| Inoue | TGF | A | Acetylcholine (muscarinic) | ACM1 | M1 | acetylcholine | Physiological | - | - | 1' | - | 6.5 | 7.0 | 7.4 | 5.5 | 6.5 | 7.1 | 7.5 | 5.7 | 94 | 88 | 82 | 76 | 6.8 | 4.8 | 4.0 | 4.3 | Inoue | |
| GPCRdb | Mean | A | Acetylcholine (muscarinic) | ACM1 | M1 | - | - | - | 1' | - | 6.2 | 6.0 | 7.6 | - | 6.3 | 6.3 | 7.7 | - | 73 | 63 | 80 | - | 5.9 | 7.9 | 38.8 | - | 2 | ||
| GPCRdb | Mean | A | Acetylcholine (muscarinic) | ACM1 | M1 | - | - | - | 1' | - | - | - | 7.6 | - | - | - | 7.7 | - | - | - | 80 | - | - | - | 38.8 | - | 3 | ||
| GPCRdb | Mean | A | Acetylcholine (muscarinic) | ACM1 | M1 | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | 4 | ||
| GPCRdb | Mean | A | Acetylcholine (muscarinic) | ACM2 | M2 | - | 2' | 1' | 2' | - | 5.2 | 7.8 | 5.9 | 4.8 | 5.7 | 7.9 | 6.2 | 5.2 | 38 | 74 | 61 | 36 | 2.6 | 29.9 | 70.3 | 1.8 | 1 | ||
| Bouvier | GEMTA | A | Acetylcholine (muscarinic) | ACM2 | M2 | acetylcholine | Physiological | 2' | 1' | 2' | - | 5.6 | 8.3 | 6.0 | - | 6.1 | 8.4 | 6.5 | - | 34 | 68 | 52 | - | 2.9 | 56.1 | 137.2 | - | Bouvier | |
| Inoue | TGF | A | Acetylcholine (muscarinic) | ACM2 | M2 | acetylcholine | Physiological | 2' | 1' | 2' | - | 4.8 | 7.3 | 5.8 | 4.8 | 5.2 | 7.4 | 6.0 | 5.2 | 43 | 80 | 70 | 36 | 2.4 | 3.8 | 3.4 | 1.8 | Inoue | |
| GPCRdb | Mean | A | Acetylcholine (muscarinic) | ACM2 | M2 | - | 2' | 1' | 2' | - | 5.2 | 7.8 | 5.9 | - | 5.7 | 7.9 | 6.2 | - | 38 | 74 | 61 | - | 2.6 | 29.9 | 70.3 | - | 2 | ||
| GPCRdb | Mean | A | Acetylcholine (muscarinic) | ACM2 | M2 | - | 2' | 1' | 2' | - | 5.2 | 7.8 | 5.9 | - | 5.7 | 7.9 | 6.2 | - | 38 | 74 | 61 | - | 2.6 | 29.9 | 70.3 | - | 3 | ||
| GPCRdb | Mean | A | Acetylcholine (muscarinic) | ACM2 | M2 | - | 2' | 1' | 2' | - | 2' | 1' | 2' | - | 2' | 1' | 2' | - | 2' | 1' | 2' | - | 2' | 1' | 2' | - | 4 | ||
| GPCRdb | Mean | A | Dopamine | DRD2 | D2 | - | - | 1' | - | - | - | 7.9 | 5.3 | - | - | 8.2 | 7.0 | - | - | 62 | 2 | - | - | 50.0 | 1.1 | - | 1 | ||
| Bouvier | GEMTA | A | Dopamine | DRD2 | D2 | dopamine | Physiological | - | 1' | - | - | - | 8.2 | 5.3 | - | - | 8.4 | 7.0 | - | - | 61 | 2 | - | - | 58.7 | 1.1 | - | Bouvier | |
| Inoue | TGF | A | Dopamine | DRD2 | D2 | dopamine | Physiological | - | 1' | - | - | - | 7.7 | - | - | - | 7.9 | - | - | - | 64 | - | - | - | 41.3 | - | - | Inoue | |
| GPCRdb | Mean | A | Dopamine | DRD2 | D2 | - | - | 1' | - | - | - | 7.9 | - | - | - | 8.2 | - | - | - | 62 | - | - | - | 50.0 | - | - | 2 | ||
| GPCRdb | Mean | A | Dopamine | DRD2 | D2 | - | - | 1' | - | - | - | 7.9 | - | - | - | 8.2 | - | - | - | 62 | - | - | - | 50.0 | - | - | 3 | ||
| GPCRdb | Mean | A | Dopamine | DRD2 | D2 | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | 4 | ||
| GPCRdb | Mean | A | Acetylcholine (muscarinic) | ACM3 | M3 | - | - | - | 1' | - | 7.0 | 6.6 | 7.8 | 6.7 | 7.0 | 6.8 | 8.0 | 6.8 | 88 | 56 | 80 | 82 | 18.8 | 15.8 | 40.7 | 15.8 | 1 | ||
| Bouvier | GEMTA | A | Acetylcholine (muscarinic) | ACM3 | M3 | acetylcholine | Physiological | - | - | 1' | - | - | 5.4 | 7.4 | - | - | 5.9 | 7.5 | - | - | 30 | 93 | - | - | 21.0 | 71.4 | - | Bouvier | |
| Inoue | TGF | A | Acetylcholine (muscarinic) | ACM3 | M3 | acetylcholine | Physiological | - | - | 1' | - | 7.0 | 7.7 | 8.2 | 6.7 | 7.0 | 7.8 | 8.4 | 6.8 | 88 | 83 | 68 | 82 | 18.8 | 10.5 | 10.0 | 15.8 | Inoue | |
| GPCRdb | Mean | A | Acetylcholine (muscarinic) | ACM3 | M3 | - | - | - | 1' | - | - | 6.6 | 7.8 | - | - | 6.8 | 8.0 | - | - | 56 | 80 | - | - | 15.8 | 40.7 | - | 2 | ||
| GPCRdb | Mean | A | Acetylcholine (muscarinic) | ACM3 | M3 | - | - | - | 1' | - | - | - | 7.8 | - | - | - | 8.0 | - | - | - | 80 | - | - | - | 40.7 | - | 3 | ||
| GPCRdb | Mean | A | Acetylcholine (muscarinic) | ACM3 | M3 | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | 4 | ||
| GPCRdb | Mean | A | Acetylcholine (muscarinic) | ACM4 | M4 | - | - | 1' | - | - | 5.2 | 7.9 | 5.8 | 5.3 | 5.8 | 8.1 | 6.2 | 5.8 | 29 | 70 | 47 | 28 | 3.3 | 19.6 | 19.8 | 2.8 | 1 | ||
| Bouvier | GEMTA | A | Acetylcholine (muscarinic) | ACM4 | M4 | acetylcholine | Physiological | - | 1' | - | - | - | 8.4 | 5.5 | - | - | 8.6 | 6.1 | - | - | 70 | 36 | - | - | 31.7 | 36.3 | - | Bouvier | |
| Inoue | TGF | A | Acetylcholine (muscarinic) | ACM4 | M4 | acetylcholine | Physiological | - | 1' | - | - | 5.2 | 7.4 | 6.2 | 5.3 | 5.8 | 7.6 | 6.4 | 5.8 | 29 | 71 | 58 | 28 | 3.3 | 7.5 | 3.3 | 2.8 | Inoue | |
| GPCRdb | Mean | A | Acetylcholine (muscarinic) | ACM4 | M4 | - | - | 1' | - | - | - | 7.9 | 5.8 | - | - | 8.1 | 6.2 | - | - | 70 | 47 | - | - | 19.6 | 19.8 | - | 2 | ||
| GPCRdb | Mean | A | Acetylcholine (muscarinic) | ACM4 | M4 | - | - | 1' | - | - | - | 7.9 | - | - | - | 8.1 | - | - | - | 70 | - | - | - | 19.6 | - | - | 3 | ||
| GPCRdb | Mean | A | Acetylcholine (muscarinic) | ACM4 | M4 | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | 4 | ||
| GPCRdb | Mean | A | Acetylcholine (muscarinic) | ACM5 | M5 | - | - | - | 1' | - | 7.5 | 8.1 | 8.3 | 7.0 | 7.5 | 8.2 | 8.5 | 7.1 | 92 | 77 | 64 | 90 | 15.1 | 10.2 | 7.0 | 10.6 | 1 | ||
| Inoue | TGF | A | Acetylcholine (muscarinic) | ACM5 | M5 | acetylcholine | Physiological | - | - | 1' | - | 7.5 | 8.1 | 8.3 | 7.0 | 7.5 | 8.2 | 8.5 | 7.1 | 92 | 77 | 64 | 90 | 15.1 | 10.2 | 7.0 | 10.6 | Inoue | |
| GPCRdb | Mean | A | Acetylcholine (muscarinic) | ACM5 | M5 | - | - | - | 1' | - | - | - | 8.3 | - | - | - | 8.5 | - | - | - | 64 | - | - | - | 7.0 | - | 2 | ||
| GPCRdb | Mean | A | Acetylcholine (muscarinic) | ACM5 | M5 | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | 3 | ||
| GPCRdb | Mean | A | Acetylcholine (muscarinic) | ACM5 | M5 | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | 4 | ||
| GPCRdb | Mean | A | Adrenoceptors | ADA1A | α1A-adrenoceptor | - | - | - | 1' | 2' | 7.5 | 6.5 | 7.7 | 7.0 | 7.7 | 7.2 | 7.8 | 7.1 | 63 | 44 | 82 | 78 | 5.4 | 6.1 | 24.4 | 8.2 | 1 | ||
| Bouvier | GEMTA | A | Adrenoceptors | ADA1A | α1A-adrenoceptor | noradrenaline | Physiological | - | - | 1' | 2' | 6.6 | 6.2 | 7.5 | - | 6.8 | 7.3 | 7.5 | - | 57 | 8 | 92 | - | 2.8 | 1.7 | 42.7 | - | Bouvier | |
| Inoue | TGF | A | Adrenoceptors | ADA1A | α1A-adrenoceptor | (-)-noradrenaline | Physiological | - | - | 1' | 2' | 8.4 | 6.8 | 7.9 | 7.0 | 8.5 | 7.0 | 8.1 | 7.1 | 69 | 81 | 73 | 78 | 8.1 | 10.6 | 6.0 | 8.2 | Inoue | |
| GPCRdb | Mean | A | Adrenoceptors | ADA1A | α1A-adrenoceptor | - | - | - | 1' | 2' | 7.5 | 6.5 | 7.7 | 7.0 | 7.7 | 7.2 | 7.8 | 7.1 | 63 | 44 | 82 | 78 | 5.4 | 6.1 | 24.4 | 8.2 | 2 | ||
| GPCRdb | Mean | A | Adrenoceptors | ADA1A | α1A-adrenoceptor | - | - | - | 1' | 2' | - | - | 7.7 | 2' | - | - | 7.8 | 2' | - | - | 82 | 2' | - | - | 24.4 | 2' | 3 | ||
| GPCRdb | Mean | A | Adrenoceptors | ADA1A | α1A-adrenoceptor | - | - | - | 1' | 2' | - | - | 1' | 2' | - | - | 1' | 2' | - | - | 1' | 2' | - | - | 1' | 2' | 4 | ||
| GPCRdb | Mean | A | Adrenoceptors | ADA1B | α1B-adrenoceptor | - | - | - | 1' | - | 7.6 | 5.6 | 7.0 | 5.6 | 7.7 | 6.0 | 7.2 | 6.1 | 85 | 41 | 76 | 35 | 11.5 | 3.5 | 4.5 | 2.4 | 1 | ||
| Inoue | TGF | A | Adrenoceptors | ADA1B | α1B-adrenoceptor | (-)-noradrenaline | Physiological | - | - | 1' | - | 7.6 | 5.6 | 7.0 | 5.6 | 7.7 | 6.0 | 7.2 | 6.1 | 85 | 41 | 76 | 35 | 11.5 | 3.5 | 4.5 | 2.4 | Inoue | |
| GPCRdb | Mean | A | Adrenoceptors | ADA1B | α1B-adrenoceptor | - | - | - | 1' | - | - | - | 7.0 | - | - | - | 7.2 | - | - | - | 76 | - | - | - | 4.5 | - | 2 | ||
| GPCRdb | Mean | A | Adrenoceptors | ADA1B | α1B-adrenoceptor | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | 3 | ||
| GPCRdb | Mean | A | Adrenoceptors | ADA1B | α1B-adrenoceptor | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | 4 | ||
| GPCRdb | Mean | A | Adrenoceptors | ADA1D | α1D-adrenoceptor | - | - | - | 1' | - | 6.3 | - | 6.4 | - | 6.8 | - | 6.9 | - | 34 | - | 36 | - | 7.1 | - | 3.3 | - | 1 | ||
| Inoue | TGF | A | Adrenoceptors | ADA1D | α1D-adrenoceptor | (-)-noradrenaline | Physiological | - | - | 1' | - | 6.3 | - | 6.4 | - | 6.8 | - | 6.9 | - | 34 | - | 36 | - | 7.1 | - | 3.3 | - | Inoue | |
| GPCRdb | Mean | A | Adrenoceptors | ADA1D | α1D-adrenoceptor | - | - | - | 1' | - | - | - | 6.4 | - | - | - | 6.9 | - | - | - | 36 | - | - | - | 3.3 | - | 2 | ||
| GPCRdb | Mean | A | Adrenoceptors | ADA1D | α1D-adrenoceptor | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | 3 | ||
| GPCRdb | Mean | A | Adrenoceptors | ADA1D | α1D-adrenoceptor | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | 4 | ||
| GPCRdb | Mean | A | Adrenoceptors | ADA2A | α2A-adrenoceptor | - | 2' | 1' | - | - | 5.2 | 8.4 | 5.5 | 6.0 | 5.8 | 8.6 | 6.1 | 6.2 | 32 | 74 | 48 | 68 | 2.8 | 10.7 | 9.2 | 42.7 | 1 | ||
| Bouvier | GEMTA | A | Adrenoceptors | ADA2A | α2A-adrenoceptor | noradrenaline | Physiological | 2' | 1' | - | - | 5.3 | 8.8 | 5.0 | 5.7 | 5.9 | 9.0 | 5.9 | 6.0 | 28 | 68 | 25 | 60 | 3.1 | 14.7 | 13.4 | 79.0 | Bouvier | |
| Inoue | TGF | A | Adrenoceptors | ADA2A | α2A-adrenoceptor | (-)-noradrenaline | Physiological | 2' | 1' | - | - | 5.2 | 8.0 | 6.0 | 6.3 | 5.7 | 8.1 | 6.2 | 6.4 | 37 | 81 | 70 | 76 | 2.4 | 6.7 | 5.0 | 6.4 | Inoue | |
| GPCRdb | Mean | A | Adrenoceptors | ADA2A | α2A-adrenoceptor | - | 2' | 1' | - | - | 5.2 | 8.4 | 5.5 | 6.0 | 5.8 | 8.6 | 6.1 | 6.2 | 32 | 74 | 48 | 68 | 2.8 | 10.7 | 9.2 | 42.7 | 2 | ||
| GPCRdb | Mean | A | Adrenoceptors | ADA2A | α2A-adrenoceptor | - | 2' | 1' | - | - | 5.2 | 8.4 | - | - | 5.8 | 8.6 | - | - | 32 | 74 | - | - | 2.8 | 10.7 | - | - | 3 | ||
| GPCRdb | Mean | A | Adrenoceptors | ADA2A | α2A-adrenoceptor | - | 2' | 1' | - | - | 2' | 1' | - | - | 2' | 1' | - | - | 2' | 1' | - | - | 2' | 1' | - | - | 4 | ||
| GPCRdb | Mean | A | Adrenoceptors | ADA2B | α2B-adrenoceptor | - | 2' | 1' | - | - | 6.2 | 8.0 | 6.2 | 7.3 | 6.5 | 8.1 | 6.7 | 7.5 | 44 | 64 | 40 | 70 | 3.4 | 14.8 | 27.0 | 4.5 | 1 | ||
| Bouvier | GEMTA | A | Adrenoceptors | ADA2B | α2B-adrenoceptor | noradrenaline | Physiological | 2' | 1' | - | - | - | 8.0 | 5.9 | - | - | 8.2 | 6.5 | - | - | 56 | 25 | - | - | 23.0 | 50.2 | - | Bouvier | |
| Inoue | TGF | A | Adrenoceptors | ADA2B | α2B-adrenoceptor | (-)-noradrenaline | Physiological | 2' | 1' | - | - | 6.2 | 8.0 | 6.6 | 7.3 | 6.5 | 8.1 | 6.9 | 7.5 | 44 | 72 | 55 | 70 | 3.4 | 6.7 | 3.7 | 4.5 | Inoue | |
| GPCRdb | Mean | A | Adrenoceptors | ADA2B | α2B-adrenoceptor | - | 2' | 1' | - | - | 6.2 | 8.0 | 6.2 | - | 6.5 | 8.1 | 6.7 | - | 44 | 64 | 40 | - | 3.4 | 14.8 | 27.0 | - | 2 | ||
| GPCRdb | Mean | A | Adrenoceptors | ADA2B | α2B-adrenoceptor | - | 2' | 1' | - | - | 2' | 8.0 | - | - | 2' | 8.1 | - | - | 2' | 64 | - | - | 2' | 14.8 | - | - | 3 | ||
| GPCRdb | Mean | A | Adrenoceptors | ADA2B | α2B-adrenoceptor | - | 2' | 1' | - | - | 2' | 1' | - | - | 2' | 1' | - | - | 2' | 1' | - | - | 2' | 1' | - | - | 4 | ||
| GPCRdb | Mean | A | Adrenoceptors | ADA2C | α2C-adrenoceptor | - | 2' | 1' | - | - | - | 8.0 | 5.3 | 5.3 | - | 8.2 | 6.3 | 6.6 | - | 60 | 14 | 5 | - | 16.5 | 4.0 | 4.4 | 1 | ||
| Bouvier | GEMTA | A | Adrenoceptors | ADA2C | α2C-adrenoceptor | noradrenaline | Physiological | 2' | 1' | - | - | - | 9.2 | 5.2 | 5.3 | - | 9.4 | 6.2 | 6.6 | - | 65 | 12 | 5 | - | 26.5 | 6.8 | 4.4 | Bouvier | |
| Inoue | TGF | A | Adrenoceptors | ADA2C | α2C-adrenoceptor | (-)-noradrenaline | Physiological | 2' | 1' | - | - | - | 6.8 | 5.5 | - | - | 7.1 | 6.4 | - | - | 55 | 15 | - | - | 6.5 | 1.1 | - | Inoue | |
| GPCRdb | Mean | A | Adrenoceptors | ADA2C | α2C-adrenoceptor | - | 2' | 1' | - | - | 2' | 8.0 | 5.3 | - | 2' | 8.2 | 6.3 | - | 2' | 60 | 14 | - | 2' | 16.5 | 4.0 | - | 2 | ||
| GPCRdb | Mean | A | Adrenoceptors | ADA2C | α2C-adrenoceptor | - | 2' | 1' | - | - | 2' | 8.0 | - | - | 2' | 8.2 | - | - | 2' | 60 | - | - | 2' | 16.5 | - | - | 3 | ||
| GPCRdb | Mean | A | Adrenoceptors | ADA2C | α2C-adrenoceptor | - | 2' | 1' | - | - | 2' | 1' | - | - | 2' | 1' | - | - | 2' | 1' | - | - | 2' | 1' | - | - | 4 | ||
| GPCRdb | Mean | A | Adrenoceptors | ADRB1 | β1-adrenoceptor | - | 1' | 2' | - | - | 8.7 | 6.3 | 6.8 | 6.0 | 8.8 | 7.0 | 7.3 | 6.7 | 76 | 27 | 44 | 29 | 8.0 | 4.5 | 15.8 | 6.6 | 1 | ||
| Bouvier | GEMTA | A | Adrenoceptors | ADRB1 | β1-adrenoceptor | noradrenaline | Physiological | 1' | 2' | - | - | 9.6 | 6.1 | 6.1 | 5.8 | 9.7 | 6.7 | 6.9 | 6.2 | 84 | 30 | 31 | 46 | 7.5 | 4.7 | 23.0 | 11.8 | Bouvier | |
| Inoue | TGF | A | Adrenoceptors | ADRB1 | β1-adrenoceptor | isoprenaline | Surrogate | 1' | 2' | - | - | 7.8 | 6.5 | 7.5 | 6.3 | 8.0 | 7.2 | 7.7 | 7.2 | 67 | 24 | 58 | 12 | 8.4 | 4.3 | 8.7 | 1.4 | Inoue | |
| GPCRdb | Mean | A | Adrenoceptors | ADRB1 | β1-adrenoceptor | - | 1' | 2' | - | - | 8.7 | 6.3 | 6.8 | 6.0 | 8.8 | 7.0 | 7.3 | 6.7 | 76 | 27 | 44 | 29 | 8.0 | 4.5 | 15.8 | 6.6 | 2 | ||
| GPCRdb | Mean | A | Adrenoceptors | ADRB1 | β1-adrenoceptor | - | 1' | 2' | - | - | 8.7 | 6.3 | - | - | 8.8 | 7.0 | - | - | 76 | 27 | - | - | 8.0 | 4.5 | - | - | 3 | ||
| GPCRdb | Mean | A | Adrenoceptors | ADRB1 | β1-adrenoceptor | - | 1' | 2' | - | - | 1' | 2' | - | - | 1' | 2' | - | - | 1' | 2' | - | - | 1' | 2' | - | - | 4 | ||
| GPCRdb | Mean | A | Adrenoceptors | ADRB2 | β2-adrenoceptor | - | 1' | 2' | - | - | 7.2 | 5.8 | 7.1 | - | 7.4 | 6.4 | 7.5 | - | 70 | 29 | 49 | - | 4.8 | - | 28.6 | - | 1 | ||
| Bouvier | GEMTA | A | Adrenoceptors | ADRB2 | β2-adrenoceptor | noradrenaline | Physiological | 1' | 2' | - | - | 8.2 | - | 6.3 | - | 8.3 | - | 6.5 | - | 83 | - | 72 | - | 3.3 | - | 55.8 | - | Bouvier | |
| Inoue | TGF | A | Adrenoceptors | ADRB2 | β2-adrenoceptor | isoprenaline | Surrogate | 1' | 2' | - | - | 6.8 | - | 6.6 | - | 7.3 | - | 7.2 | - | 30 | - | 24 | - | 6.4 | - | 1.5 | - | Inoue | |
| Roth | TGF | A | Adrenoceptors | ADRB2 | β2-adrenoceptor | (-)-adrenaline | Physiological | 1' | 2' | - | - | 6.6 | 5.8 | 8.5 | - | 6.6 | 6.4 | 8.8 | - | 97 | 29 | 52 | - | - | - | - | - | Roth | |
| GPCRdb | Mean | A | Adrenoceptors | ADRB2 | β2-adrenoceptor | - | 1' | 2' | - | - | 7.2 | 5.8 | 7.1 | - | 7.4 | 6.4 | 7.5 | - | 70 | 29 | 49 | - | 4.8 | 2' | 28.6 | - | 2 | ||
| GPCRdb | Mean | A | Adrenoceptors | ADRB2 | β2-adrenoceptor | - | 1' | 2' | - | - | 7.2 | 2' | 7.1 | - | 7.4 | 2' | 7.5 | - | 70 | 2' | 49 | - | 4.8 | 2' | - | - | 3 | ||
| GPCRdb | Mean | A | Adrenoceptors | ADRB2 | β2-adrenoceptor | - | 1' | 2' | - | - | 7.2 | 2' | - | - | 7.4 | 2' | - | - | 70 | 2' | - | - | 1' | 2' | - | - | 4 | ||
| GPCRdb | Mean | A | Adrenoceptors | ADRB3 | β3-adrenoceptor | - | 1' | 2' | - | - | 4.9 | - | - | - | 5.3 | - | - | - | 44 | - | - | - | 7.7 | - | - | - | 1 | ||
| Inoue | TGF | A | Adrenoceptors | ADRB3 | β3-adrenoceptor | isoprenaline | Surrogate | 1' | 2' | - | - | 4.9 | - | - | - | 5.3 | - | - | - | 44 | - | - | - | 7.7 | - | - | - | Inoue | |
| GPCRdb | Mean | A | Adrenoceptors | ADRB3 | β3-adrenoceptor | - | 1' | 2' | - | - | 4.9 | 2' | - | - | 5.3 | 2' | - | - | 44 | 2' | - | - | 7.7 | 2' | - | - | 2 | ||
| GPCRdb | Mean | A | Adrenoceptors | ADRB3 | β3-adrenoceptor | - | 1' | 2' | - | - | 1' | 2' | - | - | 1' | 2' | - | - | 1' | 2' | - | - | 1' | 2' | - | - | 3 | ||
| GPCRdb | Mean | A | Adrenoceptors | ADRB3 | β3-adrenoceptor | - | 1' | 2' | - | - | 1' | 2' | - | - | 1' | 2' | - | - | 1' | 2' | - | - | 1' | 2' | - | - | 4 | ||
| GPCRdb | Mean | A | Dopamine | DRD1 | D1 | - | 1' | - | - | - | 6.9 | 5.2 | 6.2 | - | 7.2 | 5.7 | 6.6 | - | 56 | 36 | 52 | - | 5.7 | 5.5 | 28.6 | - | 1 | ||
| Bouvier | GEMTA | A | Dopamine | DRD1 | D1 | dopamine | Physiological | 1' | - | - | - | 8.6 | 5.4 | 7.4 | - | 8.8 | 5.8 | 7.7 | - | 65 | 42 | 60 | - | 3.2 | 8.2 | 52.9 | - | Bouvier | |
| Inoue | TGF | A | Dopamine | DRD1 | D1 | dopamine | Physiological | 1' | - | - | - | 5.2 | 5.0 | 5.1 | - | 5.5 | 5.6 | 5.5 | - | 48 | 29 | 43 | - | 8.1 | 2.8 | 4.3 | - | Inoue | |
| GPCRdb | Mean | A | Dopamine | DRD1 | D1 | - | 1' | - | - | - | 6.9 | 5.2 | 6.2 | - | 7.2 | 5.7 | 6.6 | - | 56 | 36 | 52 | - | 5.7 | 5.5 | 28.6 | - | 2 | ||
| GPCRdb | Mean | A | Dopamine | DRD1 | D1 | - | 1' | - | - | - | 6.9 | - | - | - | 7.2 | - | - | - | 56 | - | - | - | 5.7 | - | - | - | 3 | ||
| GPCRdb | Mean | A | Dopamine | DRD1 | D1 | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 4 | ||
| GPCRdb | Mean | A | Dopamine | DRD3 | D3 | - | - | 1' | - | - | - | 7.2 | - | - | - | 7.8 | - | - | - | 25 | - | - | - | 3.2 | - | - | 1 | ||
| Inoue | TGF | A | Dopamine | DRD3 | D3 | dopamine | Physiological | - | 1' | - | - | - | 7.2 | - | - | - | 7.8 | - | - | - | 25 | - | - | - | 3.2 | - | - | Inoue | |
| GPCRdb | Mean | A | Dopamine | DRD3 | D3 | - | - | 1' | - | - | - | 7.2 | - | - | - | 7.8 | - | - | - | 25 | - | - | - | 3.2 | - | - | 2 | ||
| GPCRdb | Mean | A | Dopamine | DRD3 | D3 | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | 3 | ||
| GPCRdb | Mean | A | Dopamine | DRD3 | D3 | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | 4 | ||
| GPCRdb | Mean | A | Dopamine | DRD4 | D4 | - | - | 1' | - | - | - | 7.3 | - | - | - | 7.5 | - | - | - | 66 | - | - | - | 279.5 | - | - | 1 | ||
| Inoue | TGF | A | Dopamine | DRD4 | D4 | dopamine | Physiological | - | 1' | - | - | - | 7.3 | - | - | - | 7.5 | - | - | - | 66 | - | - | - | 279.5 | - | - | Inoue | |
| GPCRdb | Mean | A | Dopamine | DRD4 | D4 | - | - | 1' | - | - | - | 7.3 | - | - | - | 7.5 | - | - | - | 66 | - | - | - | 279.5 | - | - | 2 | ||
| GPCRdb | Mean | A | Dopamine | DRD4 | D4 | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | 3 | ||
| GPCRdb | Mean | A | Dopamine | DRD4 | D4 | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | 4 | ||
| GPCRdb | Mean | A | Dopamine | DRD5 | D5 | - | 1' | - | - | - | 7.3 | 5.5 | 6.9 | 5.6 | 7.7 | 6.5 | 7.3 | 6.6 | 53 | 15 | 50 | 10 | 6.0 | 4.5 | 20.2 | 1.2 | 1 | ||
| Bouvier | GEMTA | A | Dopamine | DRD5 | D5 | dopamine | Physiological | 1' | - | - | - | 8.4 | 5.3 | 7.7 | - | 8.6 | 6.6 | 7.9 | - | 76 | 8 | 72 | - | 7.8 | 6.2 | 36.9 | - | Bouvier | |
| Inoue | TGF | A | Dopamine | DRD5 | D5 | dopamine | Physiological | 1' | - | - | - | 6.2 | 5.7 | 6.1 | 5.6 | 6.7 | 6.4 | 6.7 | 6.6 | 30 | 22 | 27 | 10 | 4.3 | 2.7 | 3.6 | 1.2 | Inoue | |
| GPCRdb | Mean | A | Dopamine | DRD5 | D5 | - | 1' | - | - | - | 7.3 | 5.5 | 6.9 | - | 7.7 | 6.5 | 7.3 | - | 53 | 15 | 50 | - | 6.0 | 4.5 | 20.2 | - | 2 | ||
| GPCRdb | Mean | A | Dopamine | DRD5 | D5 | - | 1' | - | - | - | 7.3 | - | - | - | 7.7 | - | - | - | 53 | - | - | - | 6.0 | - | - | - | 3 | ||
| GPCRdb | Mean | A | Dopamine | DRD5 | D5 | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 4 | ||
| GPCRdb | Mean | A | Histamine | HRH1 | H1 | - | - | - | 1' | - | 6.3 | 7.0 | 7.5 | 6.0 | 6.5 | 7.2 | 8.0 | 6.2 | 58 | 72 | 44 | 52 | 4.5 | 20.6 | 19.2 | 7.7 | 1 | ||
| Bouvier | GEMTA | A | Histamine | HRH1 | H1 | histamine | Physiological | - | - | 1' | - | 5.5 | 6.5 | 7.8 | 6.0 | 5.8 | 6.6 | 8.2 | 6.2 | 49 | 91 | 52 | 56 | 2.9 | 37.9 | 35.7 | 11.2 | Bouvier | |
| Inoue | TGF | A | Histamine | HRH1 | H1 | histamine | Physiological | - | - | 1' | - | 7.1 | 7.4 | 7.3 | 5.9 | 7.3 | 7.7 | 7.8 | 6.2 | 66 | 52 | 37 | 48 | 6.0 | 3.4 | 2.6 | 4.2 | Inoue | |
| GPCRdb | Mean | A | Histamine | HRH1 | H1 | - | - | - | 1' | - | 6.3 | 7.0 | 7.5 | 6.0 | 6.5 | 7.2 | 8.0 | 6.2 | 58 | 72 | 44 | 52 | 4.5 | 20.6 | 19.2 | 7.7 | 2 | ||
| GPCRdb | Mean | A | Histamine | HRH1 | H1 | - | - | - | 1' | - | - | - | 7.5 | - | - | - | 8.0 | - | - | - | 44 | - | - | - | 19.2 | - | 3 | ||
| GPCRdb | Mean | A | Histamine | HRH1 | H1 | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | 4 | ||
| GPCRdb | Mean | A | Histamine | HRH2 | H2 | - | 2' | - | 1' | - | 6.3 | 4.5 | 5.7 | 4.8 | 6.5 | 5.4 | 6.2 | 5.4 | 62 | 20 | 41 | 29 | 3.5 | 8.9 | 25.1 | 5.3 | 1 | ||
| Bouvier | GEMTA | A | Histamine | HRH2 | H2 | histamine | Physiological | 2' | - | 1' | - | 7.0 | 4.1 | 6.5 | 4.6 | 7.1 | 5.1 | 6.7 | 5.0 | 79 | 12 | 65 | 46 | 3.5 | 15.7 | 49.3 | 9.9 | Bouvier | |
| Inoue | TGF | A | Histamine | HRH2 | H2 | histamine | Physiological | 2' | - | 1' | - | 5.7 | 5.0 | 4.9 | 4.9 | 6.0 | 5.7 | 5.7 | 5.8 | 44 | 28 | 17 | 12 | 3.4 | 2.1 | 0.9 | 0.7 | Inoue | |
| GPCRdb | Mean | A | Histamine | HRH2 | H2 | - | 2' | - | 1' | - | 6.3 | 4.5 | 5.7 | 4.8 | 6.5 | 5.4 | 6.2 | 5.4 | 62 | 20 | 41 | 29 | 3.5 | 8.9 | 25.1 | 5.3 | 2 | ||
| GPCRdb | Mean | A | Histamine | HRH2 | H2 | - | 2' | - | 1' | - | 6.3 | - | 5.7 | - | 6.5 | - | 6.2 | - | 62 | - | 41 | - | 3.5 | - | 25.1 | - | 3 | ||
| GPCRdb | Mean | A | Histamine | HRH2 | H2 | - | 2' | - | 1' | - | 2' | - | 1' | - | 2' | - | 1' | - | 2' | - | 1' | - | 2' | - | 1' | - | 4 | ||
| GPCRdb | Mean | A | Histamine | HRH3 | H3 | - | - | 1' | - | - | - | 6.3 | 5.6 | 4.9 | - | 6.6 | 6.1 | 5.8 | - | 62 | 30 | 13 | - | 10.8 | 5.0 | 2.4 | 1 | ||
| Inoue | TGF | A | Histamine | HRH3 | H3 | histamine | Physiological | - | 1' | - | - | - | 6.3 | 5.6 | 4.9 | - | 6.6 | 6.1 | 5.8 | - | 62 | 30 | 13 | - | 10.8 | 5.0 | 2.4 | Inoue | |
| GPCRdb | Mean | A | Histamine | HRH3 | H3 | - | - | 1' | - | - | - | 6.3 | - | - | - | 6.6 | - | - | - | 62 | - | - | - | 10.8 | - | - | 2 | ||
| GPCRdb | Mean | A | Histamine | HRH3 | H3 | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | 3 | ||
| GPCRdb | Mean | A | Histamine | HRH3 | H3 | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | 4 | ||
| GPCRdb | Mean | A | Histamine | HRH4 | H4 | - | - | 1' | - | - | 5.3 | 6.4 | 5.8 | 5.6 | 6.6 | 7.1 | 6.8 | 6.7 | 6 | 26 | 9 | 8 | 0.9 | 3.2 | 1.1 | 1.3 | 1 | ||
| Inoue | TGF | A | Histamine | HRH4 | H4 | histamine | Physiological | - | 1' | - | - | 5.3 | 6.4 | 5.8 | 5.6 | 6.6 | 7.1 | 6.8 | 6.7 | 6 | 26 | 9 | 8 | 0.9 | 3.2 | 1.1 | 1.3 | Inoue | |
| GPCRdb | Mean | A | Histamine | HRH4 | H4 | - | - | 1' | - | - | - | 6.4 | - | - | - | 7.1 | - | - | - | 26 | - | - | - | 3.2 | - | - | 2 | ||
| GPCRdb | Mean | A | Histamine | HRH4 | H4 | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | 3 | ||
| GPCRdb | Mean | A | Histamine | HRH4 | H4 | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | 4 | ||
| GPCRdb | Mean | A | Trace amine | TAAR1 | TA1 | - | 1' | - | 2' | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 1 | ||
| GPCRdb | Mean | A | Trace amine | TAAR1 | TA1 | - | 1' | - | 2' | - | 1' | - | 2' | - | 1' | - | 2' | - | 1' | - | 2' | - | 1' | - | 2' | - | 2 | ||
| GPCRdb | Mean | A | Trace amine | TAAR1 | TA1 | - | 1' | - | 2' | - | 1' | - | 2' | - | 1' | - | 2' | - | 1' | - | 2' | - | 1' | - | 2' | - | 3 | ||
| GPCRdb | Mean | A | Trace amine | TAAR1 | TA1 | - | 1' | - | 2' | - | 1' | - | 2' | - | 1' | - | 2' | - | 1' | - | 2' | - | 1' | - | 2' | - | 4 | ||
| GPCRdb | Mean | A | Angiotensin | AGTR1 | AT1 | - | - | 1' | 1' | - | 8.9 | 8.2 | 9.4 | 9.0 | 9.1 | 8.8 | 9.8 | 9.2 | 50 | 33 | 52 | 78 | 9.8 | 9.2 | 21.4 | 27.8 | 1 | ||
| Bouvier | GEMTA | A | Angiotensin | AGTR1 | AT1 | angiotensin II | Physiological | - | 1' | 1' | - | - | 7.1 | 8.6 | 8.8 | - | 8.2 | 9.1 | 8.9 | - | 8 | 33 | 91 | - | 2.8 | 29.5 | 29.2 | Bouvier | |
| Inoue | TGF | A | Angiotensin | AGTR1 | AT1 | angiotensin II | Physiological | - | 1' | 1' | - | 8.9 | 9.3 | 10.3 | 9.2 | 9.1 | 9.5 | 10.4 | 9.4 | 50 | 58 | 71 | 64 | 9.8 | 15.6 | 13.3 | 26.4 | Inoue | |
| GPCRdb | Mean | A | Angiotensin | AGTR1 | AT1 | - | - | 1' | 1' | - | - | 8.2 | 9.4 | 9.0 | - | 8.8 | 9.8 | 9.2 | - | 33 | 52 | 78 | - | 9.2 | 21.4 | 27.8 | 2 | ||
| GPCRdb | Mean | A | Angiotensin | AGTR1 | AT1 | - | - | 1' | 1' | - | - | 8.2 | 9.4 | - | - | 8.8 | 9.8 | - | - | 33 | 52 | - | - | 9.2 | 21.4 | - | 3 | ||
| GPCRdb | Mean | A | Angiotensin | AGTR1 | AT1 | - | - | 1' | 1' | - | - | 1' | 1' | - | - | 1' | 1' | - | - | 1' | 1' | - | - | 1' | 1' | - | 4 | ||
| GPCRdb | Mean | A | Angiotensin | AGTR2 | AT2 | - | - | 1' | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 1 | ||
| GPCRdb | Mean | A | Angiotensin | AGTR2 | AT2 | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | 2 | ||
| GPCRdb | Mean | A | Angiotensin | AGTR2 | AT2 | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | 3 | ||
| GPCRdb | Mean | A | Angiotensin | AGTR2 | AT2 | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | 4 | ||
| GPCRdb | Mean | A | Apelin | APJ | apelin | - | - | 1' | - | - | - | 8.1 | 6.2 | 6.2 | - | 8.4 | 7.4 | 7.2 | - | 46 | 10 | 12 | - | 16.7 | 1.9 | 6.2 | 1 | ||
| Bouvier | GEMTA | A | Apelin | APJ | apelin | [Pyr1]apelin-13 | Physiological | - | 1' | - | - | - | 9.1 | 5.8 | 6.7 | - | 9.3 | 7.3 | 7.7 | - | 48 | 4 | 12 | - | 20.1 | 2.2 | 7.4 | Bouvier | |
| Inoue | TGF | A | Apelin | APJ | apelin | apelin-13 | Physiological | - | 1' | - | - | - | 7.0 | 6.6 | 5.7 | - | 7.4 | 7.5 | 6.6 | - | 45 | 15 | 12 | - | 13.3 | 1.6 | 5.0 | Inoue | |
| GPCRdb | Mean | A | Apelin | APJ | apelin | - | - | 1' | - | - | - | 8.1 | 6.2 | 6.2 | - | 8.4 | 7.4 | 7.2 | - | 46 | 10 | 12 | - | 16.7 | 1.9 | 6.2 | 2 | ||
| GPCRdb | Mean | A | Apelin | APJ | apelin | - | - | 1' | - | - | - | 8.1 | - | - | - | 8.4 | - | - | - | 46 | - | - | - | 16.7 | - | - | 3 | ||
| GPCRdb | Mean | A | Apelin | APJ | apelin | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | 4 | ||
| GPCRdb | Mean | A | Bombesin | NMBR | BB1 | - | - | - | 1' | - | 9.8 | 10.1 | 10.0 | 10.1 | 10.0 | 10.2 | 10.3 | 10.2 | 63 | 66 | 62 | 62 | 9.4 | 8.5 | 5.0 | 7.5 | 1 | ||
| Inoue | TGF | A | Bombesin | NMBR | BB1 | neuromedin B | Physiological | - | - | 1' | - | 9.8 | 10.1 | 10.0 | 10.1 | 10.0 | 10.2 | 10.3 | 10.2 | 63 | 66 | 62 | 62 | 9.4 | 8.5 | 5.0 | 7.5 | Inoue | |
| GPCRdb | Mean | A | Bombesin | NMBR | BB1 | - | - | - | 1' | - | - | - | 10.0 | - | - | - | 10.3 | - | - | - | 62 | - | - | - | 5.0 | - | 2 | ||
| GPCRdb | Mean | A | Bombesin | NMBR | BB1 | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | 3 | ||
| GPCRdb | Mean | A | Bombesin | NMBR | BB1 | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | 4 | ||
| GPCRdb | Mean | A | Bombesin | GRPR | BB2 | - | - | - | 1' | - | 9.6 | 9.6 | 9.8 | 9.9 | 9.7 | 9.7 | 10.0 | 10.1 | 78 | 74 | 69 | 82 | 6.5 | 4.3 | 2.9 | 6.5 | 1 | ||
| Inoue | TGF | A | Bombesin | GRPR | BB2 | bombesin | Physiological | - | - | 1' | - | 9.6 | 9.6 | 9.8 | 9.9 | 9.7 | 9.7 | 10.0 | 10.1 | 78 | 74 | 69 | 82 | 6.5 | 4.3 | 2.9 | 6.5 | Inoue | |
| GPCRdb | Mean | A | Bombesin | GRPR | BB2 | - | - | - | 1' | - | - | - | 9.8 | - | - | - | 10.0 | - | - | - | 69 | - | - | - | 2.9 | - | 2 | ||
| GPCRdb | Mean | A | Bombesin | GRPR | BB2 | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | 3 | ||
| GPCRdb | Mean | A | Bombesin | GRPR | BB2 | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | 4 | ||
| GPCRdb | Mean | A | Bombesin | BRS3 | BB3 | - | - | - | 1' | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 1 | ||
| GPCRdb | Mean | A | Bombesin | BRS3 | BB3 | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | 2 | ||
| GPCRdb | Mean | A | Bombesin | BRS3 | BB3 | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | 3 | ||
| GPCRdb | Mean | A | Bombesin | BRS3 | BB3 | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | 4 | ||
| GPCRdb | Mean | A | Bradykinin | BKRB1 | B1 | - | - | 1' | 1' | - | 7.3 | 6.8 | 7.0 | 7.4 | 7.8 | 7.4 | 7.8 | 7.8 | 38 | 28 | 20 | 40 | 3.4 | 3.3 | 10.8 | 3.3 | 1 | ||
| Bouvier | GEMTA | A | Bradykinin | BKRB1 | B1 | kallidin | Physiological | - | 1' | 1' | - | - | 5.9 | 6.2 | - | - | 6.8 | 7.0 | - | - | 17 | 18 | - | - | 3.8 | 19.5 | - | Bouvier | |
| Inoue | TGF | A | Bradykinin | BKRB1 | B1 | bradykinin | Physiological | - | 1' | 1' | - | 7.3 | 7.7 | 7.8 | 7.4 | 7.8 | 8.1 | 8.5 | 7.8 | 38 | 38 | 23 | 40 | 3.4 | 2.9 | 2.2 | 3.3 | Inoue | |
| GPCRdb | Mean | A | Bradykinin | BKRB1 | B1 | - | - | 1' | 1' | - | - | 6.8 | 7.0 | - | - | 7.4 | 7.8 | - | - | 28 | 20 | - | - | 3.3 | 10.8 | - | 2 | ||
| GPCRdb | Mean | A | Bradykinin | BKRB1 | B1 | - | - | 1' | 1' | - | - | 6.8 | 7.0 | - | - | 7.4 | 7.8 | - | - | 28 | 20 | - | - | 3.3 | 10.8 | - | 3 | ||
| GPCRdb | Mean | A | Bradykinin | BKRB1 | B1 | - | - | 1' | 1' | - | - | 1' | 1' | - | - | 1' | 1' | - | - | 1' | 1' | - | - | 1' | 1' | - | 4 | ||
| GPCRdb | Mean | A | Bradykinin | BKRB2 | B2 | - | 1' | 1' | 1' | - | 8.1 | 8.7 | 9.7 | 9.4 | 8.3 | 8.9 | 9.8 | 9.6 | 52 | 63 | 80 | 72 | 6.5 | 9.4 | 44.4 | 21.0 | 1 | ||
| Bouvier | GEMTA | A | Bradykinin | BKRB2 | B2 | kallidin | Physiological | 1' | 1' | 1' | - | - | 7.8 | 9.3 | 9.5 | - | 8.1 | 9.4 | 9.7 | - | 52 | 91 | 68 | - | 10.8 | 80.3 | 27.5 | Bouvier | |
| Inoue | TGF | A | Bradykinin | BKRB2 | B2 | kallidin | Physiological | 1' | 1' | 1' | - | 8.1 | 9.5 | 10.1 | 9.3 | 8.3 | 9.7 | 10.2 | 9.4 | 52 | 74 | 69 | 76 | 6.5 | 7.9 | 8.4 | 14.5 | Inoue | |
| GPCRdb | Mean | A | Bradykinin | BKRB2 | B2 | - | 1' | 1' | 1' | - | 8.1 | 8.7 | 9.7 | 9.4 | 8.3 | 8.9 | 9.8 | 9.6 | 52 | 63 | 80 | 72 | 6.5 | 9.4 | 44.4 | 21.0 | 2 | ||
| GPCRdb | Mean | A | Bradykinin | BKRB2 | B2 | - | 1' | 1' | 1' | - | 1' | 8.7 | 9.7 | - | 1' | 8.9 | 9.8 | - | 1' | 63 | 80 | - | 1' | 9.4 | 44.4 | - | 3 | ||
| GPCRdb | Mean | A | Bradykinin | BKRB2 | B2 | - | 1' | 1' | 1' | - | 1' | 1' | 1' | - | 1' | 1' | 1' | - | 1' | 1' | 1' | - | 1' | 1' | 1' | - | 4 | ||
| GPCRdb | Mean | A | Cholecystokinin | CCKAR | CCK1 | - | 2' | - | 1' | - | 9.2 | 9.5 | 10.1 | 10.0 | 9.4 | 9.7 | 10.2 | 10.1 | 70 | 74 | 83 | 93 | 8.7 | 31.8 | 98.3 | 15.3 | 1 | ||
| Bouvier | GEMTA | A | Cholecystokinin | CCKAR | CCK1 | CCK-8 | Physiological | 2' | - | 1' | - | 8.1 | 8.5 | 9.4 | 9.8 | 8.5 | 8.8 | 9.6 | 9.9 | 40 | 49 | 68 | 88 | 4.3 | 48.3 | 186.6 | 25.6 | Bouvier | |
| Inoue | TGF | A | Cholecystokinin | CCKAR | CCK1 | CCK-8 | Physiological | 2' | - | 1' | - | 10.4 | 10.5 | 10.8 | 10.2 | 10.4 | 10.5 | 10.8 | 10.2 | 100 | 99 | 98 | 98 | 13.1 | 15.4 | 10.1 | 5.0 | Inoue | |
| GPCRdb | Mean | A | Cholecystokinin | CCKAR | CCK1 | - | 2' | - | 1' | - | 9.2 | 9.5 | 10.1 | 10.0 | 9.4 | 9.7 | 10.2 | 10.1 | 70 | 74 | 83 | 93 | 8.7 | 31.8 | 98.3 | 15.3 | 2 | ||
| GPCRdb | Mean | A | Cholecystokinin | CCKAR | CCK1 | - | 2' | - | 1' | - | 9.2 | - | 10.1 | - | 9.4 | - | 10.2 | - | 70 | - | 83 | - | 8.7 | - | 98.3 | - | 3 | ||
| GPCRdb | Mean | A | Cholecystokinin | CCKAR | CCK1 | - | 2' | - | 1' | - | 2' | - | 1' | - | 2' | - | 1' | - | 2' | - | 1' | - | 2' | - | 1' | - | 4 | ||
| GPCRdb | Mean | A | Cholecystokinin | GASR | CCK2 | - | - | - | 1' | - | 9.8 | 9.7 | 10.1 | 9.6 | 9.9 | 9.9 | 10.3 | 9.7 | 72 | 70 | 67 | 72 | 12.6 | 11.2 | 7.0 | 29.0 | 1 | ||
| Inoue | TGF | A | Cholecystokinin | GASR | CCK2 | CCK-8 | Physiological | - | - | 1' | - | 9.8 | 9.7 | 10.1 | 9.6 | 9.9 | 9.9 | 10.3 | 9.7 | 72 | 70 | 67 | 72 | 12.6 | 11.2 | 7.0 | 29.0 | Inoue | |
| GPCRdb | Mean | A | Cholecystokinin | GASR | CCK2 | - | - | - | 1' | - | - | - | 10.1 | - | - | - | 10.3 | - | - | - | 67 | - | - | - | 7.0 | - | 2 | ||
| GPCRdb | Mean | A | Cholecystokinin | GASR | CCK2 | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | 3 | ||
| GPCRdb | Mean | A | Cholecystokinin | GASR | CCK2 | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | 4 | ||
| GPCRdb | Mean | A | Complement peptide | C5AR1 | C5a1 | - | - | 1' | 2' | - | - | 9.0 | 9.3 | - | - | 9.2 | 9.4 | - | - | 67 | 66 | - | - | 21.5 | 112.9 | - | 1 | ||
| Bouvier | GEMTA | A | Complement peptide | C5AR1 | C5a1 | C5a | Physiological | - | 1' | 2' | - | - | 9.0 | 9.3 | - | - | 9.2 | 9.4 | - | - | 67 | 66 | - | - | 21.5 | 112.9 | - | Bouvier | |
| GPCRdb | Mean | A | Complement peptide | C5AR1 | C5a1 | - | - | 1' | 2' | - | - | 9.0 | 9.3 | - | - | 9.2 | 9.4 | - | - | 67 | 66 | - | - | 21.5 | 112.9 | - | 2 | ||
| GPCRdb | Mean | A | Complement peptide | C5AR1 | C5a1 | - | - | 1' | 2' | - | - | 1' | 2' | - | - | 1' | 2' | - | - | 1' | 2' | - | - | 1' | 2' | - | 3 | ||
| GPCRdb | Mean | A | Complement peptide | C5AR1 | C5a1 | - | - | 1' | 2' | - | - | 1' | 2' | - | - | 1' | 2' | - | - | 1' | 2' | - | - | 1' | 2' | - | 4 | ||
| GPCRdb | Mean | A | Endothelin | EDNRA | ETA | - | - | - | 1' | - | 8.9 | 10.0 | 9.8 | 10.2 | 9.2 | 10.1 | 9.9 | 10.4 | 61 | 90 | 78 | 76 | 6.9 | 20.2 | 52.8 | 18.1 | 1 | ||
| Bouvier | GEMTA | A | Endothelin | EDNRA | ETA | endothelin-1 | Physiological | - | - | 1' | - | 8.1 | 9.8 | 9.3 | 10.3 | 8.6 | 9.9 | 9.5 | 10.6 | 35 | 85 | 65 | 58 | 2.4 | 28.5 | 97.3 | 22.4 | Bouvier | |
| Inoue | TGF | A | Endothelin | EDNRA | ETA | endothelin-1 | Physiological | - | - | 1' | - | 9.7 | 10.2 | 10.2 | 10.2 | 9.8 | 10.2 | 10.3 | 10.2 | 87 | 95 | 90 | 95 | 11.3 | 11.9 | 8.2 | 13.8 | Inoue | |
| GPCRdb | Mean | A | Endothelin | EDNRA | ETA | - | - | - | 1' | - | 8.9 | 10.0 | 9.8 | 10.2 | 9.2 | 10.1 | 9.9 | 10.4 | 61 | 90 | 78 | 76 | 6.9 | 20.2 | 52.8 | 18.1 | 2 | ||
| GPCRdb | Mean | A | Endothelin | EDNRA | ETA | - | - | - | 1' | - | - | - | 9.8 | - | - | - | 9.9 | - | - | - | 78 | - | - | - | 52.8 | - | 3 | ||
| GPCRdb | Mean | A | Endothelin | EDNRA | ETA | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | 4 | ||
| GPCRdb | Mean | A | Endothelin | EDNRB | ETB | - | 1' | 1' | 1' | - | 9.6 | 10.2 | 9.9 | 10.2 | 9.7 | 10.3 | 10.1 | 10.3 | 64 | 82 | 68 | 81 | 4.9 | 4.7 | 5.7 | 6.8 | 1 | ||
| Inoue | TGF | A | Endothelin | EDNRB | ETB | endothelin-1 | Physiological | 1' | 1' | 1' | - | 9.6 | 10.2 | 9.9 | 10.2 | 9.7 | 10.3 | 10.1 | 10.3 | 64 | 82 | 68 | 81 | 4.9 | 4.7 | 5.7 | 6.8 | Inoue | |
| GPCRdb | Mean | A | Endothelin | EDNRB | ETB | - | 1' | 1' | 1' | - | 9.6 | 10.2 | 9.9 | - | 9.7 | 10.3 | 10.1 | - | 64 | 82 | 68 | - | 4.9 | 4.7 | 5.7 | - | 2 | ||
| GPCRdb | Mean | A | Endothelin | EDNRB | ETB | - | 1' | 1' | 1' | - | 1' | 1' | 1' | - | 1' | 1' | 1' | - | 1' | 1' | 1' | - | 1' | 1' | 1' | - | 3 | ||
| GPCRdb | Mean | A | Endothelin | EDNRB | ETB | - | 1' | 1' | 1' | - | 1' | 1' | 1' | - | 1' | 1' | 1' | - | 1' | 1' | 1' | - | 1' | 1' | 1' | - | 4 | ||
| GPCRdb | Mean | A | Formylpeptide | FPR1 | FPR1 | - | - | 1' | - | - | - | 6.6 | 6.5 | - | - | 7.4 | 7.2 | - | - | 20 | 19 | - | - | 1.7 | 1.5 | - | 1 | ||
| Inoue | TGF | A | Formylpeptide | FPR1 | FPR1 | fMet-Leu-Phe | Physiological | - | 1' | - | - | - | 6.6 | 6.5 | - | - | 7.4 | 7.2 | - | - | 20 | 19 | - | - | 1.7 | 1.5 | - | Inoue | |
| GPCRdb | Mean | A | Formylpeptide | FPR1 | FPR1 | - | - | 1' | - | - | - | 6.6 | - | - | - | 7.4 | - | - | - | 20 | - | - | - | 1.7 | - | - | 2 | ||
| GPCRdb | Mean | A | Formylpeptide | FPR1 | FPR1 | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | 3 | ||
| GPCRdb | Mean | A | Formylpeptide | FPR1 | FPR1 | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | 4 | ||
| GPCRdb | Mean | A | Formylpeptide | FPR2 | FPR2/ALX | - | - | 1' | 2' | - | 5.1 | 6.3 | 6.1 | 5.7 | 6.2 | 6.7 | 6.7 | 6.6 | 6 | 46 | 33 | 12 | 1.1 | 7.7 | 3.1 | 6.5 | 1 | ||
| Inoue | TGF | A | Formylpeptide | FPR2 | FPR2/ALX | WKYMVM | Surrogate | - | 1' | 2' | - | 5.1 | 6.3 | 6.1 | 5.7 | 6.2 | 6.7 | 6.7 | 6.6 | 6 | 46 | 33 | 12 | 1.1 | 7.7 | 3.1 | 6.5 | Inoue | |
| GPCRdb | Mean | A | Formylpeptide | FPR2 | FPR2/ALX | - | - | 1' | 2' | - | - | 6.3 | 6.1 | - | - | 6.7 | 6.7 | - | - | 46 | 33 | - | - | 7.7 | 3.1 | - | 2 | ||
| GPCRdb | Mean | A | Formylpeptide | FPR2 | FPR2/ALX | - | - | 1' | 2' | - | - | 1' | 2' | - | - | 1' | 2' | - | - | 1' | 2' | - | - | 1' | 2' | - | 3 | ||
| GPCRdb | Mean | A | Formylpeptide | FPR2 | FPR2/ALX | - | - | 1' | 2' | - | - | 1' | 2' | - | - | 1' | 2' | - | - | 1' | 2' | - | - | 1' | 2' | - | 4 | ||
| GPCRdb | Mean | A | Formylpeptide | FPR3 | FPR3 | - | - | 1' | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 1 | ||
| GPCRdb | Mean | A | Formylpeptide | FPR3 | FPR3 | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | 2 | ||
| GPCRdb | Mean | A | Formylpeptide | FPR3 | FPR3 | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | 3 | ||
| GPCRdb | Mean | A | Formylpeptide | FPR3 | FPR3 | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | 4 | ||
| GPCRdb | Mean | A | Galanin | GALR1 | GAL1 | - | - | 1' | - | - | 6.2 | 7.7 | 6.7 | 6.6 | 7.0 | 7.9 | 7.2 | 7.2 | 15 | 63 | 36 | 23 | 10.4 | 31.3 | 9.6 | 15.5 | 1 | ||
| Inoue | TGF | A | Galanin | GALR1 | GAL1 | galanin | Physiological | - | 1' | - | - | 6.2 | 7.7 | 6.7 | 6.6 | 7.0 | 7.9 | 7.2 | 7.2 | 15 | 63 | 36 | 23 | 10.4 | 31.3 | 9.6 | 15.5 | Inoue | |
| GPCRdb | Mean | A | Galanin | GALR1 | GAL1 | - | - | 1' | - | - | - | 7.7 | - | - | - | 7.9 | - | - | - | 63 | - | - | - | 31.3 | - | - | 2 | ||
| GPCRdb | Mean | A | Galanin | GALR1 | GAL1 | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | 3 | ||
| GPCRdb | Mean | A | Galanin | GALR1 | GAL1 | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | 4 | ||
| GPCRdb | Mean | A | Galanin | GALR2 | GAL2 | - | - | 2' | 1' | 2' | - | 7.5 | 8.2 | 7.8 | - | 7.9 | 8.4 | 8.2 | - | 36 | 49 | 44 | - | 4.3 | 5.2 | 6.8 | 1 | ||
| Inoue | TGF | A | Galanin | GALR2 | GAL2 | galanin | Physiological | - | 2' | 1' | 2' | - | 7.5 | 8.2 | 7.8 | - | 7.9 | 8.4 | 8.2 | - | 36 | 49 | 44 | - | 4.3 | 5.2 | 6.8 | Inoue | |
| GPCRdb | Mean | A | Galanin | GALR2 | GAL2 | - | - | 2' | 1' | 2' | - | 7.5 | 8.2 | 7.8 | - | 7.9 | 8.4 | 8.2 | - | 36 | 49 | 44 | - | 4.3 | 5.2 | 6.8 | 2 | ||
| GPCRdb | Mean | A | Galanin | GALR2 | GAL2 | - | - | 2' | 1' | 2' | - | 2' | 1' | 2' | - | 2' | 1' | 2' | - | 2' | 1' | 2' | - | 2' | 1' | 2' | 3 | ||
| GPCRdb | Mean | A | Galanin | GALR2 | GAL2 | - | - | 2' | 1' | 2' | - | 2' | 1' | 2' | - | 2' | 1' | 2' | - | 2' | 1' | 2' | - | 2' | 1' | 2' | 4 | ||
| GPCRdb | Mean | A | Galanin | GALR3 | GAL3 | - | - | 1' | - | - | - | 5.7 | 5.3 | - | - | 6.3 | 6.2 | - | - | 21 | 11 | - | - | 2.4 | 0.7 | - | 1 | ||
| Inoue | TGF | A | Galanin | GALR3 | GAL3 | galanin | Physiological | - | 1' | - | - | - | 5.7 | 5.3 | - | - | 6.3 | 6.2 | - | - | 21 | 11 | - | - | 2.4 | 0.7 | - | Inoue | |
| GPCRdb | Mean | A | Galanin | GALR3 | GAL3 | - | - | 1' | - | - | - | 5.7 | - | - | - | 6.3 | - | - | - | 21 | - | - | - | 2.4 | - | - | 2 | ||
| GPCRdb | Mean | A | Galanin | GALR3 | GAL3 | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | 3 | ||
| GPCRdb | Mean | A | Galanin | GALR3 | GAL3 | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | 4 | ||
| GPCRdb | Mean | A | Ghrelin | GHSR | ghrelin | - | - | 2' | 1' | 2' | 9.4 | 8.8 | 9.1 | 9.4 | 9.8 | 9.4 | 9.8 | 9.9 | 39 | 32 | 24 | 40 | 7.5 | 6.0 | 7.5 | 7.4 | 1 | ||
| Bouvier | GEMTA | A | Ghrelin | GHSR | ghrelin | ghrelin | Physiological | - | 2' | 1' | 2' | - | 8.2 | 8.4 | 9.2 | - | 8.8 | 9.2 | 9.7 | - | 30 | 16 | 37 | - | 7.3 | 9.5 | 5.5 | Bouvier | |
| Inoue | TGF | A | Ghrelin | GHSR | ghrelin | ibutamoren | Surrogate | - | 2' | 1' | 2' | 9.4 | 9.5 | 9.7 | 9.7 | 9.8 | 10.0 | 10.3 | 10.1 | 39 | 34 | 32 | 44 | 7.5 | 4.7 | 5.5 | 9.3 | Inoue | |
| GPCRdb | Mean | A | Ghrelin | GHSR | ghrelin | - | - | 2' | 1' | 2' | - | 8.8 | 9.1 | 9.4 | - | 9.4 | 9.8 | 9.9 | - | 32 | 24 | 40 | - | 6.0 | 7.5 | 7.4 | 2 | ||
| GPCRdb | Mean | A | Ghrelin | GHSR | ghrelin | - | - | 2' | 1' | 2' | - | 8.8 | 9.1 | 9.4 | - | 9.4 | 9.8 | 9.9 | - | 32 | 24 | 40 | - | 6.0 | 7.5 | 7.4 | 3 | ||
| GPCRdb | Mean | A | Ghrelin | GHSR | ghrelin | - | - | 2' | 1' | 2' | - | 2' | 1' | 2' | - | 2' | 1' | 2' | - | 2' | 1' | 2' | - | 2' | 1' | 2' | 4 | ||
| GPCRdb | Mean | A | Gonadotrophin-releasing hormone | GNRHR | GnRH1 | - | - | 2' | 1' | - | 9.2 | 8.4 | 9.1 | - | 9.5 | 8.9 | 9.4 | - | 56 | 34 | 45 | - | 9.3 | 3.5 | 12.3 | - | 1 | ||
| Bouvier | GEMTA | A | Gonadotrophin-releasing hormone | GNRHR | GnRH1 | GnRH I | Physiological | - | 2' | 1' | - | - | - | 8.7 | - | - | - | 9.2 | - | - | - | 32 | - | - | - | 20.9 | - | Bouvier | |
| Inoue | TGF | A | Gonadotrophin-releasing hormone | GNRHR | GnRH1 | leuprolide | Surrogate | - | 2' | 1' | - | 9.2 | 8.4 | 9.4 | - | 9.5 | 8.9 | 9.6 | - | 56 | 34 | 58 | - | 9.3 | 3.5 | 3.8 | - | Inoue | |
| GPCRdb | Mean | A | Gonadotrophin-releasing hormone | GNRHR | GnRH1 | - | - | 2' | 1' | - | - | 8.4 | 9.1 | - | - | 8.9 | 9.4 | - | - | 34 | 45 | - | - | 3.5 | 12.3 | - | 2 | ||
| GPCRdb | Mean | A | Gonadotrophin-releasing hormone | GNRHR | GnRH1 | - | - | 2' | 1' | - | - | 2' | 9.1 | - | - | 2' | 9.4 | - | - | 2' | 45 | - | - | 2' | 12.3 | - | 3 | ||
| GPCRdb | Mean | A | Gonadotrophin-releasing hormone | GNRHR | GnRH1 | - | - | 2' | 1' | - | - | 2' | 1' | - | - | 2' | 1' | - | - | 2' | 1' | - | - | 2' | 1' | - | 4 | ||
| GPCRdb | Mean | A | Kisspeptin | KISSR | kisspeptin | - | - | - | 1' | - | 7.5 | 7.5 | 8.5 | 7.1 | 7.5 | 7.7 | 8.7 | 7.3 | 70 | 66 | 61 | 63 | 5.7 | 5.1 | 4.1 | 6.7 | 1 | ||
| Inoue | TGF | A | Kisspeptin | KISSR | kisspeptin | kisspeptin-10 | Physiological | - | - | 1' | - | 7.5 | 7.5 | 8.5 | 7.1 | 7.5 | 7.7 | 8.7 | 7.3 | 70 | 66 | 61 | 63 | 5.7 | 5.1 | 4.1 | 6.7 | Inoue | |
| GPCRdb | Mean | A | Kisspeptin | KISSR | kisspeptin | - | - | - | 1' | - | - | - | 8.5 | - | - | - | 8.7 | - | - | - | 61 | - | - | - | 4.1 | - | 2 | ||
| GPCRdb | Mean | A | Kisspeptin | KISSR | kisspeptin | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | 3 | ||
| GPCRdb | Mean | A | Kisspeptin | KISSR | kisspeptin | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | 4 | ||
| GPCRdb | Mean | A | Melanin-concentrating hormone | MCHR1 | MCH1 | - | 1' | 1' | 1' | - | 7.6 | 7.9 | 7.5 | 7.1 | 7.7 | 7.9 | 7.7 | 7.3 | 82 | 84 | 73 | 60 | 9.2 | 6.5 | 4.6 | 5.4 | 1 | ||
| Inoue | TGF | A | Melanin-concentrating hormone | MCHR1 | MCH1 | melanin-concentrating hormone | Physiological | 1' | 1' | 1' | - | 7.6 | 7.9 | 7.5 | 7.1 | 7.7 | 7.9 | 7.7 | 7.3 | 82 | 84 | 73 | 60 | 9.2 | 6.5 | 4.6 | 5.4 | Inoue | |
| GPCRdb | Mean | A | Melanin-concentrating hormone | MCHR1 | MCH1 | - | 1' | 1' | 1' | - | 7.6 | 7.9 | 7.5 | - | 7.7 | 7.9 | 7.7 | - | 82 | 84 | 73 | - | 9.2 | 6.5 | 4.6 | - | 2 | ||
| GPCRdb | Mean | A | Melanin-concentrating hormone | MCHR1 | MCH1 | - | 1' | 1' | 1' | - | 1' | 1' | 1' | - | 1' | 1' | 1' | - | 1' | 1' | 1' | - | 1' | 1' | 1' | - | 3 | ||
| GPCRdb | Mean | A | Melanin-concentrating hormone | MCHR1 | MCH1 | - | 1' | 1' | 1' | - | 1' | 1' | 1' | - | 1' | 1' | 1' | - | 1' | 1' | 1' | - | 1' | 1' | 1' | - | 4 | ||
| GPCRdb | Mean | A | Melanin-concentrating hormone | MCHR2 | MCH2 | - | - | - | 1' | - | 7.8 | 7.8 | 8.3 | 7.7 | 8.0 | 7.9 | 8.4 | 7.8 | 74 | 70 | 72 | 70 | 18.0 | 12.9 | 14.2 | 18.6 | 1 | ||
| Inoue | TGF | A | Melanin-concentrating hormone | MCHR2 | MCH2 | melanin-concentrating hormone | Physiological | - | - | 1' | - | 7.8 | 7.8 | 8.3 | 7.7 | 8.0 | 7.9 | 8.4 | 7.8 | 74 | 70 | 72 | 70 | 18.0 | 12.9 | 14.2 | 18.6 | Inoue | |
| GPCRdb | Mean | A | Melanin-concentrating hormone | MCHR2 | MCH2 | - | - | - | 1' | - | - | - | 8.3 | - | - | - | 8.4 | - | - | - | 72 | - | - | - | 14.2 | - | 2 | ||
| GPCRdb | Mean | A | Melanin-concentrating hormone | MCHR2 | MCH2 | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | 3 | ||
| GPCRdb | Mean | A | Melanin-concentrating hormone | MCHR2 | MCH2 | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | 4 | ||
| GPCRdb | Mean | A | Melanocortin | MSHR | MC1 | - | 1' | - | - | - | - | - | 7.3 | - | - | - | 8.0 | - | - | - | 17 | - | - | - | 1.2 | - | 1 | ||
| Inoue | TGF | A | Melanocortin | MSHR | MC1 | α-MSH | Physiological | 1' | - | - | - | - | - | 7.3 | - | - | - | 8.0 | - | - | - | 17 | - | - | - | 1.2 | - | Inoue | |
| GPCRdb | Mean | A | Melanocortin | MSHR | MC1 | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 2 | ||
| GPCRdb | Mean | A | Melanocortin | MSHR | MC1 | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 3 | ||
| GPCRdb | Mean | A | Melanocortin | MSHR | MC1 | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 4 | ||
| GPCRdb | Mean | A | Melanocortin | ACTHR | MC2 | - | 1' | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 1 | ||
| GPCRdb | Mean | A | Melanocortin | ACTHR | MC2 | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 2 | ||
| GPCRdb | Mean | A | Melanocortin | ACTHR | MC2 | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 3 | ||
| GPCRdb | Mean | A | Melanocortin | ACTHR | MC2 | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 4 | ||
| GPCRdb | Mean | A | Melanocortin | MC3R | MC3 | - | 1' | - | - | - | 8.4 | 7.7 | 9.2 | 7.4 | 9.1 | 8.6 | 9.8 | 8.2 | 48 | 16 | 34 | 20 | 3.7 | 5.6 | 51.2 | 8.0 | 1 | ||
| Bouvier | GEMTA | A | Melanocortin | MC3R | MC3 | γ-MSH | Physiological | 1' | - | - | - | 9.5 | 7.7 | 10.3 | 6.7 | 9.6 | 8.4 | 10.6 | 7.1 | 89 | 22 | 55 | 34 | 6.3 | 10.1 | 101.4 | 15.2 | Bouvier | |
| Inoue | TGF | A | Melanocortin | MC3R | MC3 | α-MSH | Physiological | 1' | - | - | - | 7.3 | 7.6 | 8.0 | 8.1 | 8.5 | 8.7 | 9.0 | 9.3 | 7 | 9 | 12 | 6 | 1.1 | 1.1 | 1.0 | 0.8 | Inoue | |
| GPCRdb | Mean | A | Melanocortin | MC3R | MC3 | - | 1' | - | - | - | 8.4 | 7.7 | 9.2 | 7.4 | 9.1 | 8.6 | 9.8 | 8.2 | 48 | 16 | 34 | 20 | 3.7 | 5.6 | 51.2 | 8.0 | 2 | ||
| GPCRdb | Mean | A | Melanocortin | MC3R | MC3 | - | 1' | - | - | - | 8.4 | - | - | - | 9.1 | - | - | - | 48 | - | - | - | 3.7 | - | - | - | 3 | ||
| GPCRdb | Mean | A | Melanocortin | MC3R | MC3 | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 1' | - | - | - | 4 | ||
| GPCRdb | Mean | A | Melanocortin | MC4R | MC4 | - | 1' | - | - | - | 7.3 | 6.3 | 7.6 | 4.7 | 7.8 | 7.3 | 8.0 | 5.7 | 44 | 15 | 48 | 10 | 4.2 | 2.8 | 39.8 | 9.0 | 1 | ||
| Bouvier | GEMTA | A | Melanocortin | MC4R | MC4 | α-MSH | Physiological | 1' | - | - | - | 7.9 | 6.1 | 8.1 | 4.7 | 8.2 | 7.5 | 8.3 | 5.7 | 55 | 4 | 64 | 10 | 4.5 | 1.6 | 76.8 | 9.0 | Bouvier | |
| Inoue | TGF | A | Melanocortin | MC4R | MC4 | α-MSH | Physiological | 1' | - | - | - | 6.8 | 6.5 | 7.1 | - | 7.3 | 7.1 | 7.6 | - | 34 | 26 | 31 | - | 3.8 | 4.0 | 2.7 | - | Inoue | |
| GPCRdb | Mean | A | Melanocortin | MC4R | MC4 | - | 1' | - | - | - | 7.3 | 6.3 | 7.6 | - | 7.8 | 7.3 | 8.0 | - | 44 | 15 | 48 | - | 4.2 | 2.8 | 39.8 | - | 2 | ||
| GPCRdb | Mean | A | Melanocortin | MC4R | MC4 | - | 1' | ||||||||||||||||||||||