Mutant Browser

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Protein name Generic number Position Segment Mutation FoldChange or Qual Exp Type Ligand Reference Review
Protein name Generic number Segment Position Mutation FoldChange or Qual Exp Type Ligand Reference Review
ccr5_rat 316 C-term K => A N/A N/A Labrosse B et al (2001)


Residue

Diagrams

ICL1 K K L K ICL1ECL1 E W V F ECL1ICL2 A V F A I K A R ICL2ECL2 R S Q K E G S H Y T C S P H F L H I ECL2ICL3 R N E ICL3ECL3 L N ECL3N-term M D F Q G S I P T Y I Y D I D Y S M S A P C Q N-termC-term K H I V K R F C K H C S I F Q Q V N P D R V S S V Y T R S T G E Q E V S T G L C-term K V N V K Q I A A Q L L P P L Y S L V F I F G F V G N M M V F L I L I S C S M T D I Y L F N L A I S D L L F L L T L P F W A H Y A A N G N I M C K L F T G I Y H I G Y F G G I F F I I L L T I D R Y L A I V H T V N F G V I T S V V T W V V A V F V S L P E I I F M Q Y R F W K H F Q T L K M V I L S L I L P L L V M V I C Y S G I L N T L F R C K K R H R A V R L I F A I M I V Y F L F W T P Y N I V L L L T T F Q E Y F G N C S S S N R L D Q A M Q V T E T L G M T H C C L N P V I Y A F V G E K L S V F R N Y F F R
Download: PNG | SVG Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A
M N G V F G F I F V L S Y L P P L L Q A 1 F N L A I S D L L F L L T L P F W A H Y 2 L I I F F I G G F Y G I H Y I G T F L K 3 G V I T S V V T W V V A V F V S L P E 4 Y C I V M V L L P L I L S L I V M K L T Q 5 F A I M I V Y F L F W T P Y N I V L L L 6 V P N L C C H T M G L T E T V Q M A Q 7
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Residue Table


GPCRdb(A)
GPCRdb(A)
CCR5