Mutant Browser

Download
Protein name Generic number Position Segment Mutation FoldChange or Qual Exp Type Ligand Reference Review
Protein name Generic number Segment Position Mutation FoldChange or Qual Exp Type Ligand Reference Review
cltr1_human 3.35x35 106 TM3 N => A N/A N/A Dupre DJ et al (2004)
cltr1_human 6.34x35 232 TM6 I => R N/A N/A Dupre DJ et al (2004)


Residue

Diagrams

ICL1 Y H K K ICL1ECL1 G I W L F ECL1ICL2 P V Q N I N L V ICL2ECL2 K P Q K D E K N N T K C F E P P Q ECL2ICL3 K S M K K ICL3ECL3 E T K ECL3N-term M D E T G N L T V S N-termC-term H S L S S V T Y V P R K K A S L P E K G E E I C K V C-term S A T C H D T I D D F R N Q V Y S T L Y S M I S V V G F F G N G F V L Y V L I K T S A F Q V Y M I N L A V A D L L C V C T L P L R V V Y Y V H K G D F L C R L S T Y A L Y V N L Y C S I F F M T A M S F F R C I A I V F T Q K K A R F V C V G I W I F V I L T S S P F L M A D N Q T K N H V L V L H Y V S L F V G F I I P F V I I I V C Y T M I I L T L L K N L S S H K K A I G M I M V V T A A F L V S F M P Y H I Q R T I H L H F L H N P C D S V L R M Q K S V V I T L S L A A S N C C F D P L L Y F F S G G N L S T F R K R F R K
Download: PNG | SVG Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A
G N G F F G V V S I M S Y L T S Y V Q N 1 I N L A V A D L L C V C T L P L R V V Y 2 A T M F F I S C Y L N V Y L A Y T S L R 3 A R F V C V G I W I F V I L T S S P F 4 Y C V I I I V F P I I F G V F L S V Y H L 5 I M V V T A A F V L S F M P Y H I Q R T I 6 L P D F C C N S A A L S L T I V V S K 7
Download: PNG | SVG




Residue Table


GPCRdb(A)
GPCRdb(A)
CysLT1 receptor
TM3
3x35 3.35x35 N106
TM6
6x35 6.34x35 I232