Mutant Browser

Download
Protein name Generic number Position Segment Mutation FoldChange or Qual Exp Type Ligand Reference Review
Protein name Generic number Segment Position Mutation FoldChange or Qual Exp Type Ligand Reference Review
gpr17_human 3.24x24 131 TM3 A => T N/A N/A Jiao X et al (2012)


Residue

Diagrams

ICL1 H K S G ICL1ECL1 N H W P F ECL1ICL2 P V K S L K L R ICL2ECL2 P Q T V Q T N H T V V C L Q L ECL2ICL3 G L R V ICL3ECL3 H G A ECL3N-term M S K R S W W A G S R K P P R E M L K L S G S D S S Q S M N G L E V A P P G L I T N F S L A T A E Q C N-termC-term K R L K G P P P S F E G K T N E S S L S A K S E L C-term G Q E T P L E N M L F A S F Y L L D F I L A L V G N T L A L W L F I R D T P A N V F L M H L A V A D L S C V L V L P T R L V Y H F S G G E I A C R L T G F L F Y L N M Y A S I Y F L T C I S A D R F L A I V H R P L Y A H L A C A F L W V V V A V A M A P L L V S Y R E K A S H H A L V S L A V A F T F P F I T T V T C Y L L I I R S L R Q E K R L K T K A V R M I A I V L A I F L V C F V P Y H V N R S V Y V L H Y R S S C A T Q R I L A L A N R I T S C L T S L N G A L D P I M Y F F V A E K L C N F R H A L L C G
Download: PNG | SVG Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A
T N G V L A L I F D L L Y F S A F L M N 1 M H L A V A D L S C V L V L P T R L V Y 2 C T L F Y I S A Y M N L Y F L F G T L R 3 A H L A C A F L W V V V A V A M A P L 4 Y C T V T T I F P F T F A V A L S V L A H 5 A I V L A I F L V C F V P Y H V N R S V 6 I P D L A G N L S T L C S T I R N A L 7
Download: PNG | SVG




Residue Table


GPCRdb(A)
GPCRdb(A)
GPR17
TM3
3x24 3.24x24 A131